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Select item 107825601.

AgRP neurons coordinate the mitigation of activity-based anorexia

Ames K. Sutton Hickey, Sean C. Duane, Laura E. Mickelsen, Eva O. Karolczak, Ahmed M. Shamma, Anna Skillings, Chia Li, Michael J. Krashes

Mol Psychiatry. Author manuscript; available in PMC 2024 Jan 11.

Published in final edited form as: Mol Psychiatry. 2023 Apr; 28(4): 1622–1635. Published online 2022 Dec 28. doi: 10.1038/s41380-022-01932-w

PMCID:: PMC10782560

Abstract Article PDF–1.6M

Select item 104127312.

Nuclear receptor 5A2 regulation of Agrp underlies olanzapine-induced hyperphagia

Rizaldy C. Zapata, Dinghong Zhang, Avraham Libster, Alessandra Porcu, Patricia Montilla-Perez, Aisha Nur, Baijie Xu, Zhi Zhang, Stephanie M. Correa, Chen Liu, Francesca Telese, Olivia Osborn

Mol Psychiatry. 2023; 28(5): 1857–1867. Published online 2023 Feb 10. doi: 10.1038/s41380-023-01981-9

PMCID:: PMC10412731

Abstract Article PDF–1.6M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79511374.

Discovery of Molecular Interactions of the Human Melanocortin-4 Receptor (hMC4R) Asp189 (D189) Amino Acid with the Endogenous G-Protein-Coupled Receptor (GPCR) Antagonist Agouti-Related Protein (AGRP) Provides Insights to AGRP’s Inverse Agonist Pharmacology at the hMC4R

Mark D. Ericson, Erica M. Haslach, Sathya M. Schnell, Katie T. Freeman, Zhimin M. Xiang, Frederico P. Portillo, Robert Speth, Sally A. Litherland, Carrie Haskell-Luevano

ACS Chem Neurosci. Author manuscript; available in PMC 2022 Feb 3.

Published in final edited form as: ACS Chem Neurosci. 2021 Feb 3; 12(3): 542–556. Published online 2021 Jan 20. doi: 10.1021/acschemneuro.0c00755

PMCID:: PMC7951137

Abstract Article PDF–3.1M

Select item 72793845.

Mitochondrial Dynamics and Microglia as New Targets in Metabolism Regulation

Martina Chiurazzi, Martina Di Maro, Mauro Cozzolino, Antonio Colantuoni

Int J Mol Sci. 2020 May; 21(10): 3450. Published online 2020 May 13. doi: 10.3390/ijms21103450

PMCID:: PMC7279384

Abstract Article PDF–1.1M

Select item 67776366.

Plasma Agouti-Related Protein Levels in Acromegaly and Effects of Surgical or Pegvisomant Therapy

Pamela U Freda, Carlos Reyes-Vidal, Zhezhen Jin, Mya Pugh, Sunil K Panigrahi, Jeffrey N Bruce, Sharon L Wardlaw

J Clin Endocrinol Metab. 2019 Nov; 104(11): 5453–5461. Published online 2019 Jul 30. doi: 10.1210/jc.2019-01079

PMCID:: PMC6777636

Abstract Article

Select item 63645087.

Plasma Agouti-Related Protein and Cortisol Levels in Cushing Disease: Evidence for the Regulation of Agouti-Related Protein by Glucocorticoids in Humans

Gabrielle Page-Wilson, Jane B Peters, Sunil K Panigrahi, Thomas P Jacobs, Judith Korner, Marc Otten, Jeffrey N Bruce, Sharon L Wardlaw

J Clin Endocrinol Metab. 2019 Mar; 104(3): 961–969. Published online 2018 Dec 28. doi: 10.1210/jc.2018-01909

PMCID:: PMC6364508

Abstract Article

Select item 55316118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 54180619.

Rafael Palomino, Hsiau-Wei Lee, Glenn L. Millhauser

J Biol Chem. 2017 May 5; 292(18): 7651–7661. Published online 2017 Mar 6. doi: 10.1074/jbc.M116.772822

PMCID:: PMC5418061

Abstract Article PDF–1.6M

Select item 455688310.

Proopiomelanocortin, agouti-related protein, and leptin in human cerebrospinal fluid: correlations with body weight and adiposity

Gabrielle Page-Wilson, Kana Meece, Anne White, Michael Rosenbaum, Rudolph L. Leibel, Richard Smiley, Sharon L. Wardlaw

Am J Physiol Endocrinol Metab. 2015 Sep 1; 309(5): E458–E465. Published online 2015 Jul 7. doi: 10.1152/ajpendo.00206.2015

PMCID:: PMC4556883

Abstract Article

Select item 418407311.

Clinical Utility of Plasma POMC and AgRP Measurements in the Differential Diagnosis of ACTH-Dependent Cushing's Syndrome

Gabrielle Page-Wilson, Pamela U. Freda, Thomas P. Jacobs, Alexander G. Khandji, Jeffrey N. Bruce, Sandra T. Foo, Kana Meece, Anne White, Sharon L. Wardlaw

J Clin Endocrinol Metab. 2014 Oct; 99(10): E1838–E1845. Published online 2014 Jul 11. doi: 10.1210/jc.2014-1448

PMCID:: PMC4184073

Abstract Article

Select item 390901812.

Genetic Association Analysis of 30 Genes Related to Obesity in a European American Population

Peng Li, Hemant K. Tiwari, Wan-Yu Lin, David B. Allison, Wendy K. Chung, Rudolph L. Leibel, Nengjun Yi, Nianjun Liu

Int J Obes (Lond) Author manuscript; available in PMC 2014 Nov 1.

Published in final edited form as: Int J Obes (Lond). 2014 May; 38(5): 724–729. Published online 2013 Jul 31. doi: 10.1038/ijo.2013.140

PMCID:: PMC3909018

Abstract Article PDF–195K

Select item 353710313.

Cerebrospinal Fluid Levels of Leptin, Proopiomelanocortin, and Agouti-Related Protein in Human Pregnancy: Evidence for Leptin Resistance

Gabrielle Page-Wilson, Elena Reitman-Ivashkov, Kana Meece, Anne White, Michael Rosenbaum, Richard M. Smiley, Sharon L. Wardlaw

J Clin Endocrinol Metab. 2013 Jan; 98(1): 264–271. Published online 2012 Nov 1. doi: 10.1210/jc.2012-2309

PMCID:: PMC3537103

Abstract Article

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 296315415.

Association Study of 182 Candidate Genes in Anorexia Nervosa

Andrea Poyastro Pinheiro, Cynthia M. Bulik, Laura M. Thornton, Patrick F. Sullivan, Tammy L. Root, Cinnamon S. Bloss, Wade H. Berrettini, Nicholas J. Schork, Walter H. Kaye, Andrew W. Bergen, Pierre Magistretti, Harry Brandt, Steve Crawford, Scott Crow, Manfred M. Fichter, David Goldman, Katherine A. Halmi, Craig Johnson, Allan S. Kaplan, Pamela K. Keel, Kelly L. Klump, Maria La Via, James E. Mitchell, Michael Strober, Alessandro Rotondo, Janet Treasure, D. Blake Woodside

Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2010 Oct 25.

Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2010 Jul; 153B(5): 1070–1080. doi: 10.1002/ajmg.b.31082

PMCID:: PMC2963154

Abstract Article PDF–315K

Select item 279386316.

Hormone and glucose signalling in POMC and AgRP neurons

Bengt F Belgardt, Tomoo Okamura, Jens C Brüning

J Physiol. 2009 Nov 15; 587(Pt 22): 5305–5314. Published online 2009 Sep 21. doi: 10.1113/jphysiol.2009.179192

PMCID:: PMC2793863

Abstract Article PDF–471K

Select item 271595017.

Analysis of 30 Genes (355 SNPS) Related to Energy Homeostasis for Association with Adiposity in European-American and Yup'ik Eskimo Populations

Wendy K. Chung, Amit Patki, Naoki Matsuoka, Bert B. Boyer, Nianjun Liu, Solomon K. Musani, Anna V. Goropashnaya, Perciliz L. Tan, Nicholas Katsanis, Stephen B. Johnson, Peter K. Gregersen, David B. Allison, Rudolph L. Leibel, Hemant K. Tiwari

Hum Hered. 2009 Feb; 67(3): 193–205. Published online 2008 Dec 15. doi: 10.1159/000181158

PMCID:: PMC2715950

Abstract Article PDF–636K

Select item 271484018.

Association between a rare SNP in the second intron of human Agouti related protein gene and increased BMI

Ineta Kalnina, Ivo Kapa, Valdis Pirags, Vita Ignatovica, Helgi B Schiöth, Janis Klovins

BMC Med Genet. 2009; 10: 63. Published online 2009 Jul 14. doi: 10.1186/1471-2350-10-63

PMCID:: PMC2714840

Abstract Article PDF–281K

Select item 267671119.

Control elements in the neighboring ATPase gene influence spatiotemporal expression of the human Agouti-related protein

Olha Ilnytska, Mehmet A. Sözen, Rachel Dauterive, George Argyropoulos

J Mol Biol. Author manuscript; available in PMC 2010 May 1.

Published in final edited form as: J Mol Biol. 2009 May 1; 388(2): 239–251. Published online 2009 Mar 13. doi: 10.1016/j.jmb.2009.03.017

PMCID:: PMC2676711

Abstract Article PDF–2.0M

Select item 173576620.

Functional dimorphism of two hAgRP promoter SNPs in linkage disequilibrium

F Bai, T Rankinen, C Charbonneau, D Belsham, D Rao, C Bouchard, G Argyropoulos

J Med Genet. 2004 May; 41(5): 350–353. doi: 10.1136/jmg.2003.014092

PMCID:: PMC1735766

Summary PDF–335K

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