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Select item 114259141.

CircHIPK2 Contributes Cell Growth in Intestinal Epithelial of Colitis and Colorectal Cancer through Promoting TAZ Translation

Xixi Zeng, Jielin Tang, Qian Zhang, Chenxing Wang, Ji Qi, Yusi Wei, Jiali Xu, Kaiyuan Yang, Zuolin Zhou, Hao Wu, Jiarong Luo, Yi Jiang, Zengqiang Song, Jinyu Wu, Jianmin Wu

Adv Sci (Weinh) 2024 Sep; 11(34): 2401588. Published online 2024 Jul 9. doi: 10.1002/advs.202401588

PMCID:: PMC11425914

Abstract Article PDF–5.0M

Select item 112632382.

YAP/TAZ-TEAD activity promotes the malignant transformation of cervical intraepithelial neoplasia through enhancing the characteristics and Warburg effect of cancer stem cells

Shu Li, Xing Li, Yong-bin Yang, Su-fang Wu

Apoptosis. 2024; 29(7-8): 1198–1210. Published online 2024 Mar 29. doi: 10.1007/s10495-023-01935-0

PMCID:: PMC11263238

Abstract Article PDF–7.2M

Select item 112370293.

The Hippo pathway transcription factors YAP and TAZ play HPV-type dependent roles in cervical cancer

Molly R. Patterson, Joseph A. Cogan, Rosa Cassidy, Daisy A. Theobald, Miao Wang, James A. Scarth, Chinedu A. Anene, Adrian Whitehouse, Ethan L. Morgan, Andrew Macdonald

Nat Commun. 2024; 15: 5809. Published online 2024 Jul 10. doi: 10.1038/s41467-024-49965-9

PMCID:: PMC11237029

Abstract Article PDF–4.9M

Select item 111138104.

FAT1 cadherin acts upstream of Hippo signalling through TAZ to regulate neuronal differentiation

Abdulrzag F. Ahmed, Charles E. de Bock, Lisa F. Lincz, Jay Pundavela, Ihssane Zouikr, Estelle Sontag, Hubert Hondermarck, Rick F. Thorne

Cell Mol Life Sci. 2015 Dec; 72(23): 4653–4669. Published online 2015 Jun 24. doi: 10.1007/s00018-015-1955-6

PMCID:: PMC11113810

Abstract Article PDF–2.2M

Select item 111077405.

Role of YAP/TAZ transcriptional regulators in resistance to anti-cancer therapies

Min Hwan Kim, Joon Kim

Cell Mol Life Sci. 2017 Apr; 74(8): 1457–1474. Published online 2016 Nov 8. doi: 10.1007/s00018-016-2412-x

PMCID:: PMC11107740

Abstract Article PDF–795K

Select item 110921006.

The Hippo pathway terminal effector TAZ/WWTR1 mediates oxaliplatin sensitivity in p53 proficient colon cancer cells

Věra Slaninová, Lisa Heron-Milhavet, Mathilde Robin, Laura Jeanson, Adam Aissanou, Diala Kantar, Diego Tosi, Laurent Bréhélin, Céline Gongora, Alexandre Djiane

BMC Cancer. 2024; 24: 587. Published online 2024 May 14. doi: 10.1186/s12885-024-12316-4

PMCID:: PMC11092100

Abstract Article PDF–7.8M

Select item 110719917.

An overview of signaling pathways regulating YAP/TAZ activity

Boon Chin Heng, Xuehui Zhang, Dominique Aubel, Yunyang Bai, Xiaochan Li, Yan Wei, Martin Fussenegger, Xuliang Deng

Cell Mol Life Sci. 2021 Jan; 78(2): 497–512. Published online 2020 Aug 3. doi: 10.1007/s00018-020-03579-8

PMCID:: PMC11071991

Abstract Article PDF–1.9M

Select item 110718068.

TAZ promotes PDX1-mediated insulinogenesis

Mi Gyeong Jeong, Hyo Kyeong Kim, Gibbeum Lee, Hee Yeon Won, Da Hye Yoon, Eun Sook Hwang

Cell Mol Life Sci. 2022 Mar; 79(3): 186. Published online 2022 Mar 13. doi: 10.1007/s00018-022-04216-2

PMCID:: PMC11071806

Abstract Article PDF–16M

Select item 110449109.

Phase separation of TAZ compartmentalizes the transcription machinery to promote gene expression

Yi Lu, Tiantian Wu, Orit Gutman, Huasong Lu, Qiang Zhou, Yoav I. Henis, Kunxin Luo

Nat Cell Biol. Author manuscript; available in PMC 2024 Apr 25.

Published in final edited form as: Nat Cell Biol. 2020 Apr; 22(4): 453–464. Published online 2020 Mar 23. doi: 10.1038/s41556-020-0485-0

PMCID:: PMC11044910

Abstract Article PDF–5.0M

Select item 1101487010.

Non‐canonical IKB kinases regulate YAP/TAZ and pathological vascular remodeling behaviors in pulmonary artery smooth muscle cells

Aja Aravamudhan, Paul B. Dieffenbach, Kyoung Moo Choi, Patrick A. Link, Jeffrey A. Meridew, Andrew J. Haak, Laura E. Fredenburgh, Daniel J. Tschumperlin

Physiol Rep. 2024 Apr; 12(7): e15999. Published online 2024 Apr 12. doi: 10.14814/phy2.15999

PMCID:: PMC11014870

Abstract Article PDF–2.4M

Select item 1098712011.

External Mechanical Stability Regulates Hematoma Vascularization in Bone Healing Rather than Endothelial YAP/TAZ Mechanotransduction

Julia Mehl, Saeed Khomeijani Farahani, Erik Brauer, Alexandra Klaus‐Bergmann, Tobias Thiele, Agnes Ellinghaus, Eireen Bartels‐Klein, Katharina Koch, Katharina Schmidt‐Bleek, Ansgar Petersen, Holger Gerhardt, Viola Vogel, Georg N. Duda

Adv Sci (Weinh) 2024 Apr; 11(13): 2307050. Published online 2024 Jan 25. doi: 10.1002/advs.202307050

PMCID:: PMC10987120

Abstract Article PDF–6.6M

Select item 1087587112.

Transcriptomics analysis revealed that TAZ regulates the proliferation of KIRC cells through mitophagy

Zhen He, Jianxi Shi, Bing Zhu, Zhentao Tian, Zhihong Zhang

BMC Cancer. 2024; 24: 229. Published online 2024 Feb 19. doi: 10.1186/s12885-024-11903-9

PMCID:: PMC10875871

Abstract Article PDF–4.0M

Select item 1086042813.

M2 macrophages promote subconjunctival fibrosis through YAP/TAZ signalling

Yiwei Wang, Xingchen Geng, Zhihua Guo, Dandan Chu, Ruixing Liu, Boyuan Cheng, Haohao Cui, Chengcheng Li, Jingguo Li, Zhanrong Li

Ann Med. 2024; 56(1): 2313680. Published online 2024 Feb 9. doi: 10.1080/07853890.2024.2313680

PMCID:: PMC10860428

Abstract Article PDF–12M

Select item 1085884514.

Tankyrase inhibition interferes with junction remodeling, induces leakiness, and disturbs YAP1/TAZ signaling in the endothelium

Nan Ma, Yohanes Cakrapradipta Wibowo, Phillip Wirtz, Doris Baltus, Thomas Wieland, Sepp Jansen

Naunyn Schmiedebergs Arch Pharmacol. 2024; 397(3): 1763–1789. Published online 2023 Sep 23. doi: 10.1007/s00210-023-02720-1

PMCID:: PMC10858845

Abstract Article PDF–9.4M

Select item 1082315215.

TAZ acting as a potential pathogenic biomarker to promote the development of lichen planus

Ning Wang, Ruimin Bai, Baochen Cheng, Ruiting Luo, Ke He, Wenqian Du, Tingyi Yin, Qiongwen Liang, Yan Zheng

Skin Res Technol. 2024 Feb; 30(2): e13597. Published online 2024 Jan 28. doi: 10.1111/srt.13597

PMCID:: PMC10823152

Abstract Article PDF–830K

Select item 1081395316.

TGFβ and Hippo Signaling Pathways Coordinate to Promote Acinar to Ductal Metaplasia in Human Pancreas

Michael Nipper, Yi Xu, Jun Liu, Xue Yin, Zhijie Liu, Zhengqing Ye, Jianmin Zhang, Yidong Chen, Pei Wang

Cells. 2024 Jan; 13(2): 186. Published online 2024 Jan 18. doi: 10.3390/cells13020186

PMCID:: PMC10813953

Abstract Article PDF–14M

Select item 1070176817.

TAZ facilitates breast tumor growth by promoting an immune‐suppressive tumor microenvironment

Anat Gershoni, Ori Hassin, Nishanth Belugali Nataraj, Sivan Baruch, Adi Avioz‐Seligman, Anna Chiara Pirona, Liat Fellus‐Alyagor, Tomer Meir Salame, Saptaparna Mukherjee, Giuseppe Mallel, Yosef Yarden, Yael Aylon, Moshe Oren

Mol Oncol. 2023 Dec; 17(12): 2675–2693. Published online 2023 Oct 16. doi: 10.1002/1878-0261.13525

PMCID:: PMC10701768

Abstract Article PDF–2.0M

Select item 1063025418.

The role of the FSGS disease gene product and nuclear pore protein NUP205 in regulating nuclear localization and activity of transcriptional regulators YAP and TAZ

Lioba Ester, Inês Cabrita, Michel Ventzke, Emilia Kieckhöfer, Marita Christodoulou, Amrei M Mandel, Paul Diefenhardt, Francesca Fabretti, Thomas Benzing, Sandra Habbig, Bernhard Schermer

Hum Mol Genet. 2023 Nov 15; 32(22): 3153–3165. Published online 2023 Aug 11. doi: 10.1093/hmg/ddad135

PMCID:: PMC10630254

Abstract Article PDF–1.9M

Select item 1062981519.

Epithelial Yap/Taz are required for functional alveolar regeneration following acute lung injury

Gianluca T. DiGiovanni, Wei Han, Taylor P. Sherrill, Chase J. Taylor, David S. Nichols, Natalie M. Geis, Ujjal K. Singha, Carla L. Calvi, A. Scott McCall, Molly M. Dixon, Yang Liu, Ji-Hoon Jang, Sergey S. Gutor, Vasiliy V. Polosukhin, Timothy S. Blackwell, Jonathan A. Kropski, Jason J. Gokey

JCI Insight. 2023 Oct 9; 8(19): e173374. Published online 2023 Sep 7. doi: 10.1172/jci.insight.173374