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Select item 111596441.

Role of ZNF143 in tumor growth through transcriptional regulation of DNA replication and cell‐cycle‐associated genes

Hiroto Izumi, Tetsuro Wakasugi, Shohei Shimajiri, Akihide Tanimoto, Yasuyuki Sasaguri, Eiji Kashiwagi, Yoshihiro Yasuniwa, Masaki Akiyama, Bin Han, Ying Wu, Takeshi Uchiumi, Tokuzo Arao, Kazuto Nishio, Ryuta Yamazaki, Kimitoshi Kohno

Cancer Sci. 2010 Dec; 101(12): 2538–2545. Published online 2010 Sep 23. doi: 10.1111/j.1349-7006.2010.01725.x

PMCID:: PMC11159644

Abstract Article PDF–746K

Select item 111481842.

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek

Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x

PMCID:: PMC11148184

Abstract Article PDF–8.1M

Select item 108508183.

Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7

Joseph S. Baxter, Rachel Brough, Dragomir B. Krastev, Feifei Song, Sandhya Sridhar, Aditi Gulati, John Alexander, Theodoros I. Roumeliotis, Zuza Kozik, Jyoti S. Choudhary, Syed Haider, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord

Mol Oncol. 2024 Feb; 18(2): 369–385. Published online 2023 Oct 22. doi: 10.1002/1878-0261.13537

PMCID:: PMC10850818

Abstract Article PDF–2.7M

Select item 103301854.

ZNF143 facilitates the growth and migration of glioma cells by regulating KPNA2-mediated Hippo signalling

Yan Chen, Jitao Li, Jiangchun Ma, Yizhong Bao

Sci Rep. 2023; 13: 11097. Published online 2023 Jul 9. doi: 10.1038/s41598-023-38158-x

PMCID:: PMC10330185

Abstract Article PDF–2.1M

Select item 102818845.

ATF1 promotes the malignancy of lung adenocarcinoma cells by transcriptionally regulating ZNF143 expression: ATF1 promotes the malignancy of lung adenocarcinoma cells

Jinhong Mei, Yu Liu, Yiyun Sheng, Ying Liu, Limin Chen, Hailong Wang, Minzhang Cheng, Zhenyu Zhai, Linlin Xu

Acta Biochim Biophys Sin (Shanghai) 2023 May; 55(5): 769–782. Published online 2023 May 8. doi: 10.3724/abbs.2023087

PMCID:: PMC10281884

Abstract Article PDF–4.9M

Select item 100729066.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 98430517.

ODF2L acts as a synthetic lethal partner with WEE1 inhibition in epithelial ovarian cancer models

Jie Li, Jingyi Lu, Manman Xu, Shiyu Yang, Tiantian Yu, Cuimiao Zheng, Xi Huang, Yuwen Pan, Yangyang Chen, Junming Long, Chunyu Zhang, Hua Huang, Qingyuan Dai, Bo Li, Wei Wang, Shuzhong Yao, Chaoyun Pan

J Clin Invest. 2023 Jan 17; 133(2): e161544. Published online 2023 Jan 17. doi: 10.1172/JCI161544

PMCID:: PMC9843051

Abstract Article PDF–2.9M

Select item 97936868.

Wee1 promotes cell proliferation and imatinib resistance in chronic myeloid leukemia via regulating DNA damage repair dependent on ATM-γH2AX-MDC1

Fanting Zeng, Yuhang Peng, Yuefeng Qin, Jianming Wang, Guoyun Jiang, Wenli Feng, Ying Yuan

Cell Commun Signal. 2022; 20: 199. Published online 2022 Dec 27. doi: 10.1186/s12964-022-01021-z

PMCID:: PMC9793686

Abstract Article PDF–17M

Select item 97080869.

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy

eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676

PMCID:: PMC9708086

Abstract Article PDF–8.5M

Select item 927928510.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 917759411.

Inhibiting WEE1 and IKK-RELA Crosstalk Overcomes TNFα Resistance in Head and Neck Cancers

Zhengbo Hu, Ramya Viswanathan, Hui Cheng, Jianghong Chen, Xinping Yang, Angel Huynh, Paul Clavijo, Yi An, Yvette Robbins, Christopher Silvin, Clint Allen, Pinar Ormanoglu, Scott Martin, Shaleeka Cornelius, Anthony Saleh, Zhong Chen, Carter Van Waes, Ethan L. Morgan

Mol Cancer Res. Author manuscript; available in PMC 2022 Dec 3.

Published in final edited form as: Mol Cancer Res. 2022 Jun 3; 20(6): 867–882. doi: 10.1158/1541-7786.MCR-21-0624

PMCID:: PMC9177594

Abstract Article PDF–1.4M

Select item 911973612.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 910523513.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 898621314.

ZNF143 Expression is Associated with COPD and Tumor Microenvironment in Non-Small Cell Lung Cancer

Zhenxing Feng, Yan Yin, Bin Liu, Lei Wang, Miaomiao Chen, Yue Zhu, Hong Zhang, Daqiang Sun, Jianwen Qin

Int J Chron Obstruct Pulmon Dis. 2022; 17: 685–700. Published online 2022 Apr 2. doi: 10.2147/COPD.S352392

PMCID:: PMC8986213

Abstract Article PDF–11M

Select item 898608715.

WEE1 kinase is a therapeutic vulnerability in CIC-DUX4 undifferentiated sarcoma

Rovingaile Kriska M. Ponce, Nicholas J. Thomas, Nam Q. Bui, Tadashi Kondo, Ross A. Okimoto

JCI Insight. 2022 Mar 22; 7(6): e152293. Published online 2022 Mar 22. doi: 10.1172/jci.insight.152293

PMCID:: PMC8986087

Abstract Article PDF–5.2M

Select item 897405616.

BUB1B (BUB1 Mitotic Checkpoint Serine/Threonine Kinase B) promotes lung adenocarcinoma by interacting with Zinc Finger Protein ZNF143 and regulating glycolysis

Xiaolei Zhou, Yanli Yuan, Hongping Kuang, Bingxiang Tang, Hui Zhang, Manlin Zhang

Bioengineered. 2022; 13(2): 2471–2485. Published online 2022 Jan 22. doi: 10.1080/21655979.2021.2013108

PMCID:: PMC8974056

Abstract Article PDF–3.7M

Select item 889702217.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 882889518.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 881658819.

miR-138-5p Inhibits the Growth and Invasion of Glioma Cells by Regulating WEE1

Jianwu Gong, Zhi Tang, Zhengtao Yu, Zhiyong Deng, Yan Liu, Nianjun Ren, Lei Wang, Zhengwen He

Anal Cell Pathol (Amst) 2022; 2022: 7809882. Published online 2022 Jan 28. doi: 10.1155/2022/7809882

PMCID:: PMC8816588

Abstract Article PDF–3.3M

Select item 876907220.

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584

PMCID:: PMC8769072

Abstract Article PDF–2.9M

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