PMC Links for GEO Profiles (Select 35941777) - PMC

Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 104541582.

Expression Levels of the Tnni3k Gene in the Heart Are Highly Associated with Cardiac and Glucose Metabolism-Related Phenotypes and Functional Pathways

Qingqing Gu, Buyan-Ochir Orgil, Akhilesh Kumar Bajpai, Yufeng Chen, David G. Ashbrook, Athena Starlard-Davenport, Jeffrey A. Towbin, Djamel Lebeche, Enkhsaikhan Purevjav, Hongzhuan Sheng, Lu Lu

Int J Mol Sci. 2023 Aug; 24(16): 12759. Published online 2023 Aug 14. doi: 10.3390/ijms241612759

PMCID:: PMC10454158

Abstract Article PDF–3.8M

Select item 101139573.

Cardiomyocyte ploidy is dynamic during postnatal development and varies across genetic backgrounds

Samantha K. Swift, Alexandra L. Purdy, Mary E. Kolell, Kaitlyn G. Andresen, Caitlin Lahue, Tyler Buddell, Kaelin A. Akins, Christoph D. Rau, Caitlin C. O'Meara, Michaela Patterson

Development. 2023 Apr 1; 150(7): dev201318. Published online 2023 Apr 13. doi: 10.1242/dev.201318

PMCID:: PMC10113957

Abstract Article

Select item 98396004.

Cardiac Troponin I-interacting Kinase impacts cardiomyocyte S-phase activity but not cardiomyocyte proliferation

Sean P. Reuter, Mark H. Soonpaa, Dorothy Field, Ed Simpson, Michael Rubart-von der Lohe, Han Kyu Lee, Arthi Sridhar, Stephanie M. Ware, Nick Green, Xiaochun Li, Susan Ofner, Douglas A. Marchuk, Kai C. Wollert, Loren J. Field

Circulation. Author manuscript; available in PMC 2024 Jan 10.

Published in final edited form as: Circulation. 2023 Jan 10; 147(2): 142–153. Published online 2022 Nov 16. doi: 10.1161/CIRCULATIONAHA.122.061130

PMCID:: PMC9839600

Abstract Article PDF–2.3M

Select item 77882945.

The prevalent I686T human variant and loss-of-function mutations in the cardiomyocyte-specific kinase gene TNNI3K cause adverse contractility and concentric remodeling in mice

Peiheng Gan, Catalin Baicu, Hirofumi Watanabe, Kristy Wang, Ge Tao, Daniel P Judge, Michael R Zile, Takako Makita, Rupak Mukherjee, Henry M Sucov

Hum Mol Genet. 2020 Nov 1; 29(21): 3504–3515. Published online 2020 Oct 21. doi: 10.1093/hmg/ddaa234

PMCID:: PMC7788294

Abstract Article PDF–1.3M

Select item 67972186.

Tnni3k alleles influence ventricular mononuclear diploid cardiomyocyte frequency

Peiheng Gan, Michaela Patterson, Alexa Velasquez, Kristy Wang, Di Tian, Jolene J. Windle, Ge Tao, Daniel P. Judge, Takako Makita, Thomas J. Park, Henry M. Sucov

PLoS Genet. 2019 Oct; 15(10): e1008354. Published online 2019 Oct 7. doi: 10.1371/journal.pgen.1008354

PMCID:: PMC6797218

Abstract Article PDF–1.7M

Select item 57361457.

Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration

Michaela Patterson, Lindsey Barske, Ben Van Handel, Christoph D Rau, Peiheng Gan, Avneesh Sharma, Shan Parikh, Matt Denholtz, Ying Huang, Yukiko Yamaguchi, Hua Shen, Hooman Allayee, J Gage Crump, Thomas I Force, Ching-Ling Lien, Takako Makita, Aldons J Lusis, S Ram Kumar, Henry M Sucov

Nat Genet. Author manuscript; available in PMC 2018 Sep 1.

Published in final edited form as: Nat Genet. 2017 Sep; 49(9): 1346–1353. Published online 2017 Aug 7. doi: 10.1038/ng.3929

PMCID:: PMC5736145

Abstract Article PDF–1.3M

Select item 43654988.

Inhibition of the Cardiomyocyte-Specific Kinase TNNI3K Limits Oxidative Stress, Injury, and Adverse Remodeling in the Ischemic Heart

Ronald J. Vagnozzi, Gregory J. Gatto, Jr., Lara S. Kallander, Nicholas E. Hoffman, Karthik Mallilankaraman, Victoria L. T. Ballard, Brian G. Lawhorn, Patrick Stoy, Joanne Philp, Alan P. Graves, Yoshiro Naito, John J. Lepore, Erhe Gao, Muniswamy Madesh, Thomas Force

Sci Transl Med. Author manuscript; available in PMC 2015 Mar 19.

Published in final edited form as: Sci Transl Med. 2013 Oct 16; 5(207): 207ra141. doi: 10.1126/scitranslmed.3006479

PMCID:: PMC4365498

Abstract Article PDF–2.4M

Select item 41513489.

TNNI3K, a novel cardiac-specific kinase, emerging as a molecular target for the treatment of cardiac disease

Hind Lal, Firdos Ahmad, Shan Parikh, Thomas Force

Circ J. Author manuscript; available in PMC 2014 Sep 2.

Published in final edited form as: Circ J. 2014; 78(7): 1514–1519. Published online 2014 Jun 5. doi: 10.1253/circj.cj-14-0543

PMCID:: PMC4151348

Abstract Article PDF–831K

Select item 357241010.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 353551611.

Overexpression of TNNI3K, a cardiac specific MAPKKK, promotes cardiac dysfunction

Hao Tang, Kunhong Xiao, Lan Mao, Howard A. Rockman, Douglas A. Marchuk

J Mol Cell Cardiol. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: J Mol Cell Cardiol. 2013 Jan; 54: 101–111. Published online 2012 Oct 16. doi: 10.1016/j.yjmcc.2012.10.004

PMCID:: PMC3535516

Abstract Article PDF–3.7M

Select item 351654612.

Dissection of a Quantitative Trait Locus for PR Interval Duration Identifies Tnni3k as a Novel Modulator of Cardiac Conduction

Elisabeth M. Lodder, Brendon P. Scicluna, Annalisa Milano, Albert Y. Sun, Hao Tang, Carol Ann Remme, Perry D. Moerland, Michael W. T. Tanck, Geoffrey S. Pitt, Douglas A. Marchuk, Connie R. Bezzina

PLoS Genet. 2012 Dec; 8(12): e1003113. Published online 2012 Dec 6. doi: 10.1371/journal.pgen.1003113

PMCID:: PMC3516546

Abstract Article PDF–432K

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 311015114.

A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58

Shigetoshi Yokoyama, Yoshiaki Ito, Hiroe Ueno-Kudoh, Hirohito Shimizu, Kenta Uchibe, Sonia Albini, Kazuhiko Mitsuoka, Shigeru Miyaki, Minako Kiso, Akane Nagai, Tomohiro Hikata, Tadahiro Osada, Noritsugu Fukuda, Satoshi Yamashita, Daisuke Harada, Valeria Mezzano, Masataka Kasai, Pier Lorenzo Puri, Yoshihide Hayashizaki, Haruo Okado, Megumi Hashimoto, Hiroshi Asahara

Dev Cell. Author manuscript; available in PMC 2011 Jun 7.

Published in final edited form as: Dev Cell. 2009 Dec; 17(6): 836–848. doi: 10.1016/j.devcel.2009.10.011

PMCID:: PMC3110151

Abstract Article PDF–2.0M

Select item 302253415.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 273117016.

Tnni3k Modifies Disease Progression in Murine Models of Cardiomyopathy

Ferrin C. Wheeler, Hao Tang, Odessa A. Marks, Tracy N. Hadnott, Pei-Lun Chu, Lan Mao, Howard A. Rockman, Douglas A. Marchuk

PLoS Genet. 2009 Sep; 5(9): e1000647. Published online 2009 Sep 18. doi: 10.1371/journal.pgen.1000647

PMCID:: PMC2731170

Abstract Article PDF–936K

Select item 31099217.

RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer

Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki

Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600

PMCID:: PMC310992

Abstract Article PDF–3.4M

Select item 31098018.

Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes

Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki

Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100

PMCID:: PMC310980

Abstract Article PDF–1.4M

Select item 13924119.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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