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Select item 111084441.

Stable intronic sequence RNAs (sisRNAs): a new layer of gene regulation

Ismail Osman, Mandy Li-Ian Tay, Jun Wei Pek

Cell Mol Life Sci. 2016 Sep; 73(18): 3507–3519. Published online 2016 May 4. doi: 10.1007/s00018-016-2256-4

PMCID:: PMC11108444

Abstract Article PDF–1.4M

Select item 107548192.

dTrmt10A impacts Hsp70 chaperone m⁶A levels and the stress response in the Drosophila brain

Alexandra E. Perlegos, Xiuming Quan, Kirby M. Donnelly, Hui Shen, Emily J. Shields, Heidi Elashal, Kathy Fange Liu, Nancy M. Bonini

Sci Rep. 2023; 13: 22999. Published online 2023 Dec 28. doi: 10.1038/s41598-023-50272-4

PMCID:: PMC10754819

Abstract Article PDF–2.6M

Select item 101645913.

RNA binding proteins Smaug and Cup induce CCR4–NOT-dependent deadenylation of the nanos mRNA in a reconstituted system

Filip Pekovic, Christiane Rammelt, Jana Kubíková, Jutta Metz, Mandy Jeske, Elmar Wahle

Nucleic Acids Res. 2023 May 8; 51(8): 3950–3970. Published online 2023 Mar 23. doi: 10.1093/nar/gkad159

PMCID:: PMC10164591

Abstract Article PDF–4.6M

Select item 94184434.

A conserved domain of Drosophila RNA-binding protein Pumilio interacts with multiple CCR4–NOT deadenylase complex subunits to repress target mRNAs

Rebecca J. Haugen, René M. Arvola, Robert P. Connacher, Richard T. Roden, Aaron C. Goldstrohm

J Biol Chem. 2022 Sep; 298(9): 102270. Published online 2022 Jul 16. doi: 10.1016/j.jbc.2022.102270

PMCID:: PMC9418443

Abstract Article PDF–2.6M

Select item 86644865.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 77920476.

Roles of piRNAs in transposon and pseudogene regulation of germline mRNAs and lncRNAs

Chen Wang, Haifan Lin

Genome Biol. 2021; 22: 27. Published online 2021 Jan 8. doi: 10.1186/s13059-020-02221-x

PMCID:: PMC7792047

Abstract Article PDF–1.8M

Select item 73906267.

Silencing of CCR4-NOT complex subunits affects heart structure and function

Lisa Elmén, Claudia B. Volpato, Anaïs Kervadec, Santiago Pineda, Sreehari Kalvakuri, Nakissa N. Alayari, Luisa Foco, Peter P. Pramstaller, Karen Ocorr, Alessandra Rossini, Anthony Cammarato, Alexandre R. Colas, Andrew A. Hicks, Rolf Bodmer

Dis Model Mech. 2020 Jul 1; 13(7): dmm044727. Published online 2020 Jul 20. doi: 10.1242/dmm.044727

PMCID:: PMC7390626

Abstract Article

Select item 70389328.

Unique repression domains of Pumilio utilize deadenylation and decapping factors to accelerate destruction of target mRNAs

René M Arvola, Chung-Te Chang, Joseph P Buytendorp, Yevgen Levdansky, Eugene Valkov, Peter L Freddolino, Aaron C Goldstrohm

Nucleic Acids Res. 2020 Feb 28; 48(4): 1843–1871. Published online 2019 Dec 21. doi: 10.1093/nar/gkz1187

PMCID:: PMC7038932

Abstract Article PDF–8.8M

Select item 69615789.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 689046510.

Drosophila PSI controls circadian period and the phase of circadian behavior under temperature cycle via tim splicing

Lauren E Foley, Jinli Ling, Radhika Joshi, Naveh Evantal, Sebastian Kadener, Patrick Emery

eLife. 2019; 8: e50063. Published online 2019 Nov 8. doi: 10.7554/eLife.50063

PMCID:: PMC6890465

Abstract Article PDF–3.0M

Select item 676925611.

HELZ directly interacts with CCR4–NOT and causes decay of bound mRNAs

Aoife Hanet, Felix Räsch, Ramona Weber, Vincenzo Ruscica, Maria Fauser, Tobias Raisch, Duygu Kuzuoğlu-Öztürk, Chung-Te Chang, Dipankar Bhandari, Cátia Igreja, Lara Wohlbold

Life Sci Alliance. 2019 Oct; 2(5): e201900405. Published online 2019 Sep 30. doi: 10.26508/lsa.201900405

PMCID:: PMC6769256

Abstract Article PDF–2.1M

Select item 664888612.

Direct role for the Drosophila GIGYF protein in 4EHP-mediated mRNA repression

Vincenzo Ruscica, Praveen Bawankar, Daniel Peter, Sigrun Helms, Cátia Igreja, Elisa Izaurralde

Nucleic Acids Res. 2019 Jul 26; 47(13): 7035–7048. Published online 2019 May 22. doi: 10.1093/nar/gkz429

PMCID:: PMC6648886

Abstract Article PDF–2.8M

Select item 650653913.

Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila

Hagar Meltzer, Efrat Marom, Idan Alyagor, Oded Mayseless, Victoria Berkun, Netta Segal-Gilboa, Tamar Unger, David Luginbuhl, Oren Schuldiner

Nat Commun. 2019; 10: 2113. Published online 2019 May 8. doi: 10.1038/s41467-019-10140-0

PMCID:: PMC6506539

Abstract Article PDF–6.5M

Select item 616849714.

LOTUS domain protein MARF1 binds CCR4-NOT deadenylase complex to post-transcriptionally regulate gene expression in oocytes

Li Zhu, Suresh K. Kandasamy, Susan E. Liao, Ryuya Fukunaga

Nat Commun. 2018; 9: 4031. Published online 2018 Oct 2. doi: 10.1038/s41467-018-06404-w

Correction in:: Nat Commun. 2019; 10: 1074.

PMCID:: PMC6168497

Abstract Article PDF–3.4M

Select item 614641715.

Generation of Drosophila sisRNAs by Independent Transcription from Cognate Introns

Sharon Si Jia Ng, Ruther Teo Zheng, Ismail Osman, Jun Wei Pek

iScience. 2018 Jun 29; 4: 68–75. Published online 2018 May 18. doi: 10.1016/j.isci.2018.05.010

PMCID:: PMC6146417

Abstract Article PDF–2.4M

Select item 610929416.

The CCR4-NOT complex is a tumor suppressor in Drosophila melanogaster eye cancer models

Carmen Vicente, Rocco Stirparo, Sofie Demeyer, Charles E. de Bock, Olga Gielen, Mardelle Atkins, Jiekun Yan, Georg Halder, Bassem A. Hassan, Jan Cools

J Hematol Oncol. 2018; 11: 108. Published online 2018 Aug 25. doi: 10.1186/s13045-018-0650-0