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Select item 109455081.

DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response to oxidative stress

Fabian Hersperger, Tim Meyring, Pia Weber, Chintan Chhatbar, Gianni Monaco, Marc S Dionne, Katrin Paeschke, Marco Prinz, Olaf Groß, Anne-Kathrin Classen, Katrin Kierdorf

eLife. 2024; 12: RP86700. Published online 2024 Jan 8. doi: 10.7554/eLife.86700

PMCID:: PMC10945508

Abstract Article PDF–5.7M

Select item 108867412.

Understanding Developmental Cell Death Using Drosophila as a Model System

Ruchi Umargamwala, Jantina Manning, Loretta Dorstyn, Donna Denton, Sharad Kumar

Cells. 2024 Feb; 13(4): 347. Published online 2024 Feb 16. doi: 10.3390/cells13040347

PMCID:: PMC10886741

Abstract Article PDF–1.6M

Select item 104588683.

Drosophila as a Robust Model System for Assessing Autophagy: A Review

Esref Demir, Sam Kacew

Toxics. 2023 Aug; 11(8): 682. Published online 2023 Aug 8. doi: 10.3390/toxics11080682

PMCID:: PMC10458868

Abstract Article PDF–1.0M

Select item 102270804.

LC3-associated phagocytosis promotes glial degradation of axon debris after injury in Drosophila models

Áron Szabó, Virág Vincze, Aishwarya Sanjay Chhatre, András Jipa, Sarolta Bognár, Katalin Eszter Varga, Poulami Banik, Adél Harmatos-Ürmösi, Lukas J. Neukomm, Gábor Juhász

Nat Commun. 2023; 14: 3077. Published online 2023 May 29. doi: 10.1038/s41467-023-38755-4

PMCID:: PMC10227080

Abstract Article PDF–9.4M

Select item 101057365.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 90374936.

Adaptation to hypoxia in Drosophila melanogaster requires autophagy

Ayelén Valko, Sebastián Perez-Pandolfo, Eleonora Sorianello, Andreas Brech, Pablo Wappner, Mariana Melani

Autophagy. 2022; 18(4): 909–920. Published online 2021 Nov 18. doi: 10.1080/15548627.2021.1991191

PMCID:: PMC9037493

Abstract Article PDF–15M

Select item 88010227.

The role of mitophagy during oocyte aging in human, mouse, and Drosophila: implications for oocyte quality and mitochondrial disease

Rachel T Cox, Joanna Poulton, Suzannah A Williams

Reprod Fertil. 2021 Dec; 2(4): R113–R129. Published online 2021 Oct 11. doi: 10.1530/RAF-21-0060

PMCID:: PMC8801022

Abstract Article PDF–2.3M

Select item 86644868.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 86104939.

Paths and pathways that generate cell-type heterogeneity and developmental progression in hematopoiesis

Juliet R Girard, Lauren M Goins, Dung M Vuu, Mark S Sharpley, Carrie M Spratford, Shreya R Mantri, Utpal Banerjee

eLife. 2021; 10: e67516. Published online 2021 Oct 29. doi: 10.7554/eLife.67516

PMCID:: PMC8610493

Abstract Article PDF–13M

Select item 857029210.

CHMP2B regulates TDP-43 phosphorylation and cytotoxicity independent of autophagy via CK1

Xue Deng, Xing Sun, Wenkai Yue, Yongjia Duan, Rirong Hu, Kai Zhang, Jiangxia Ni, Jihong Cui, Qiangqiang Wang, Yelin Chen, Ang Li, Yanshan Fang

J Cell Biol. 2022 Jan 3; 221(1): e202103033. Published online 2021 Nov 2. doi: 10.1083/jcb.202103033

PMCID:: PMC8570292

Abstract Article PDF–6.1M

Select item 852848911.

Multiscale analysis reveals that diet-dependent midgut plasticity emerges from alterations in both stem cell niche coupling and enterocyte size

Alessandro Bonfini, Adam J Dobson, David Duneau, Jonathan Revah, Xi Liu, Philip Houtz, Nicolas Buchon

eLife. 2021; 10: e64125. Published online 2021 Sep 23. doi: 10.7554/eLife.64125

PMCID:: PMC8528489

Abstract Article PDF–12M

Select item 852224912.

Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer’s disease

Suman Rimal, Yu Li, Rasika Vartak, Ji Geng, Ishaq Tantray, Shuangxi Li, Sungun Huh, Hannes Vogel, Charles Glabe, Lea T. Grinberg, Salvatore Spina, William W. Seeley, Su Guo, Bingwei Lu

Acta Neuropathol Commun. 2021; 9: 169. Published online 2021 Oct 18. doi: 10.1186/s40478-021-01268-6

PMCID:: PMC8522249

Abstract Article PDF–2.5M

Select item 804227013.

Comprehensive Identification and Alternative Splicing of Microexons in Drosophila

Ting-Lin Pang, Zhan Ding, Shao-Bo Liang, Liang Li, Bei Zhang, Yu Zhang, Yu-Jie Fan, Yong-Zhen Xu

Front Genet. 2021; 12: 642602. Published online 2021 Mar 30. doi: 10.3389/fgene.2021.642602

PMCID:: PMC8042270

Abstract Article PDF–3.6M

Select item 792367914.

Cell type-specific modulation of healthspan by Forkhead family transcription factors in the nervous system

Ekin Bolukbasi, Nathaniel S. Woodling, Dobril K. Ivanov, Jennifer Adcott, Andrea Foley, Arjunan Rajasingam, Lauren M. Gittings, Benjamin Aleyakpo, Teresa Niccoli, Janet M. Thornton, Linda Partridge

Proc Natl Acad Sci U S A. 2021 Feb 23; 118(8): e2011491118. Published online 2021 Feb 15. doi: 10.1073/pnas.2011491118

PMCID:: PMC7923679

Abstract Article PDF–1.2M

Select item 775807015.

TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS

Kathleen M Cunningham, Kirstin Maulding, Kai Ruan, Mumine Senturk, Jonathan C Grima, Hyun Sung, Zhongyuan Zuo, Helen Song, Junli Gao, Sandeep Dubey, Jeffrey D Rothstein, Ke Zhang, Hugo J Bellen, Thomas E Lloyd

eLife. 2020; 9: e59419. Published online 2020 Dec 10. doi: 10.7554/eLife.59419

PMCID:: PMC7758070

Abstract Article PDF–6.3M

Select item 767336216.

An autophagy-dependent tubular lysosomal network synchronizes degradative activity required for muscle remodeling

Tadayoshi Murakawa, Amy A. Kiger, Yuriko Sakamaki, Mitsunori Fukuda, Naonobu Fujita

J Cell Sci. 2020 Nov 1; 133(21): jcs248336. Published online 2020 Nov 9. doi: 10.1242/jcs.248336

PMCID:: PMC7673362

Abstract Article

Select item 729602917.

Human ZKSCAN3 and Drosophila M1BP are functionally homologous transcription factors in autophagy regulation

Marine Barthez, Mathilde Poplineau, Marwa Elrefaey, Nathalie Caruso, Yacine Graba, Andrew J. Saurin

Sci Rep. 2020; 10: 9653. Published online 2020 Jun 15. doi: 10.1038/s41598-020-66377-z

PMCID:: PMC7296029

Abstract Article PDF–5.8M

Select item 706803018.

Genetic and genomic studies of pathogenic EXOSC2 mutations in the newly described disease SHRF implicate the autophagy pathway in disease pathogenesis

Xue Yang, Vafa Bayat, Nataliya DiDonato, Yang Zhao, Brian Zarnegar, Zurab Siprashvili, Vanessa Lopez-Pajares, Tao Sun, Shiying Tao, Chenjian Li, Andreas Rump, Paul Khavari, Bingwei Lu

Hum Mol Genet. 2020 Mar 13; 29(4): 541–553. Published online 2019 Oct 19. doi: 10.1093/hmg/ddz251

PMCID:: PMC7068030

Abstract Article PDF–1.3M

Select item 680589819.

IRE1 promotes neurodegeneration through autophagy-dependent neuron death in the Drosophila model of Parkinson’s disease

Cheng Yan, Jingqi Liu, Jiamei Gao, Ying Sun, Lei Zhang, Haiyun Song, Lei Xue, Lixing Zhan, Guanjun Gao, Zunji Ke, Yong Liu, Jingnan Liu

Cell Death Dis. 2019 Nov; 10(11): 800. Published online 2019 Oct 22. doi: 10.1038/s41419-019-2039-6

Correction in:: Cell Death Dis. 2020 Feb; 11(2): 150.

PMCID:: PMC6805898

Abstract Article PDF–4.9M

Select item 673673420.

A tissue and temporal-specific autophagic switch controls Drosophila pre-metamorphic nutritional checkpoints

Xueyang Pan, Thomas P. Neufeld, Michael B. O’Connor

Curr Biol. Author manuscript; available in PMC 2020 Sep 9.

Published in final edited form as: Curr Biol. 2019 Sep 9; 29(17): 2840–2851.e4. Published online 2019 Aug 15. doi: 10.1016/j.cub.2019.07.027

PMCID:: PMC6736734

Abstract Article PDF–1.4M

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