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Select item 113624591.

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation

Lisa Kofler, Lorenz Grundmann, Magdalena Gerhalter, Michael Prattes, Juliane Merl-Pham, Gertrude Zisser, Irina Grishkovskaya, Victor-Valentin Hodirnau, Martin Vareka, Rolf Breinbauer, Stefanie M. Hauck, David Haselbach, Helmut Bergler

Nat Commun. 2024; 15: 7511. Published online 2024 Aug 29. doi: 10.1038/s41467-024-51754-3

PMCID:: PMC11362459

Abstract Article PDF–3.5M

Select item 109454732.

Gle1 is required for tRNA to stimulate Dbp5 ATPase activity in vitro and promote Dbp5-mediated tRNA export in vivo in Saccharomyces cerevisiae

Arvind Arul Nambi Rajan, Ryuta Asada, Ben Montpetit

eLife. 2024; 12: RP89835. Published online 2024 Jan 8. doi: 10.7554/eLife.89835

PMCID:: PMC10945473

Abstract Article PDF–4.3M

Select item 108724773.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 108418424.

Single-molecule quantitation of RNA-binding protein occupancy and stoichiometry defines a role for Yra1 (Aly/REF) in nuclear mRNP organization

Ryuta Asada, Andrew Dominguez, Ben Montpetit

Cell Rep. Author manuscript; available in PMC 2024 Feb 5.

Published in final edited form as: Cell Rep. 2023 Nov 28; 42(11): 113415. Published online 2023 Nov 14. doi: 10.1016/j.celrep.2023.113415

PMCID:: PMC10841842

Abstract Article PDF–3.9M

Select item 107988585.

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking

Lucas J. Marmorale, Huan Jin, Thomas G. Reidy, Brandon Palomino-Alonso, Christopher J. Zysnarski, Fatima Jordan-Javed, Sagar Lahiri, Mara C. Duncan

J Cell Biol. 2024 Mar 4; 223(3): e202309047. Published online 2024 Jan 19. doi: 10.1083/jcb.202309047

PMCID:: PMC10798858

Abstract Article PDF–6.4M

Select item 107001386.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 106390617.

Yeast ribosome biogenesis factors Puf6 and Nog2 and ribosomal proteins uL2 and eL43 act in concert to facilitate the release of nascent large ribosomal subunits from the nucleolus

Amber J LaPeruta, Stefanie Hedayati, Jelena Micic, Fiona Fitzgerald, David Kim, Grace Oualline, John L Woolford

Nucleic Acids Res. 2023 Nov 10; 51(20): 11277–11290. Published online 2023 Oct 9. doi: 10.1093/nar/gkad794

PMCID:: PMC10639061

Abstract Article PDF–3.7M

Select item 105166428.

ISW1a modulates cohesin distribution in centromeric and pericentromeric regions

Ireneusz Litwin, Małgorzata Nowicka, Katarzyna Markowska, Ewa Maciaszczyk-Dziubińska, Paulina Tomaszewska, Robert Wysocki, Karol Kramarz

Nucleic Acids Res. 2023 Sep 22; 51(17): 9101–9121. Published online 2023 Jul 24. doi: 10.1093/nar/gkad612

PMCID:: PMC10516642

Abstract Article PDF–2.8M

Select item 104847329.

Surveillance of 3′ mRNA cleavage during transcription termination requires CF IB/Hrp1

Jing Li, Luisa Querl, Ivo Coban, Gabriela Salinas, Heike Krebber

Nucleic Acids Res. 2023 Sep 8; 51(16): 8758–8773. Published online 2023 Jun 23. doi: 10.1093/nar/gkad530

PMCID:: PMC10484732

Abstract Article PDF–1.7M

Select item 1029770010.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 963893511.

A guard protein mediated quality control mechanism monitors 5’-capping of pre-mRNAs

Sandra Klama, Anna G Hirsch, Ulla M Schneider, Gesa Zander, Anika Seel, Heike Krebber

Nucleic Acids Res. 2022 Oct 28; 50(19): 11301–11314. Published online 2022 Oct 28. doi: 10.1093/nar/gkac952

PMCID:: PMC9638935

Abstract Article PDF–3.5M

Select item 950796912.

Visualizing maturation factor extraction from the nascent ribosome by the AAA-ATPase Drg1

Michael Prattes, Irina Grishkovskaya, Victor-Valentin Hodirnau, Christina Hetzmannseder, Gertrude Zisser, Carolin Sailer, Vasileios Kargas, Mathias Loibl, Magdalena Gerhalter, Lisa Kofler, Alan J. Warren, Florian Stengel, David Haselbach, Helmut Bergler

Nat Struct Mol Biol. 2022; 29(9): 942–953. Published online 2022 Sep 12. doi: 10.1038/s41594-022-00832-5

PMCID:: PMC9507969

Abstract Article PDF–9.4M

Select item 940223313.

An amphipathic helix in Brl1 is required for nuclear pore complex biogenesis in S. cerevisiae

Annemarie Kralt, Matthias Wojtynek, Jonas S Fischer, Arantxa Agote-Aran, Roberta Mancini, Elisa Dultz, Elad Noor, Federico Uliana, Marianna Tatarek-Nossol, Wolfram Antonin, Evgeny Onischenko, Ohad Medalia, Karsten Weis

eLife. 2022; 11: e78385. Published online 2022 Aug 24. doi: 10.7554/eLife.78385

PMCID:: PMC9402233

Abstract Article PDF–14M

Select item 934048014.

Nuclear pore complex acetylation regulates mRNA export and cell cycle commitment in budding yeast

Mercè Gomar‐Alba, Vasilisa Pozharskaia, Bogdan Cichocki, Celia Schaal, Arun Kumar, Basile Jacquel, Gilles Charvin, J Carlos Igual, Manuel Mendoza

EMBO J. 2022 Aug; 41(15): e110271. Published online 2022 Jun 23. doi: 10.15252/embj.2021110271

PMCID:: PMC9340480

Abstract Article PDF–10M

Select item 927130715.

Sus1 maintains a normal lifespan through regulation of TREX-2 complex-mediated mRNA export

Suji Lim, Yan Liu, Byung-Ho Rhie, Chun Kim, Hong-Yeoul Ryu, Seong Hoon Ahn

Aging (Albany NY) 2022 Jun 30; 14(12): 4990–5012. Published online 2022 Jun 29. doi: 10.18632/aging.204146

PMCID:: PMC9271307

Abstract Article PDF–2.2M

Select item 920981116.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 859001217.

Unraveling the stepwise maturation of the yeast telomerase including a Cse1 and Mtr10 mediated quality control checkpoint

Anna Greta Hirsch, Daniel Becker, Jan-Philipp Lamping, Heike Krebber

Sci Rep. 2021; 11: 22174. Published online 2021 Nov 12. doi: 10.1038/s41598-021-01599-3

PMCID:: PMC8590012

Abstract Article PDF–2.6M

Select item 841532018.

Three-layered control of mRNA poly(A) tail synthesis in Saccharomyces cerevisiae

Matti Turtola, M. Cemre Manav, Ananthanarayanan Kumar, Agnieszka Tudek, Seweryn Mroczek, Paweł S. Krawczyk, Andrzej Dziembowski, Manfred Schmid, Lori A. Passmore, Ana Casañal, Torben Heick Jensen

Genes Dev. 2021 Sep 1; 35(17-18): 1290–1303. doi: 10.1101/gad.348634.121