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Select item 108987401.

Comparative exploration of mammalian deafness gene homologues in the Drosophila auditory organ shows genetic correlation between insect and vertebrate hearing

Daniel C. Sutton, Jonathan C. Andrews, Dylan M. Dolezal, Ye Jin Park, Hongjie Li, Daniel F. Eberl, Shinya Yamamoto, Andrew K. Groves

PLoS One. 2024; 19(2): e0297846. Published online 2024 Feb 27. doi: 10.1371/journal.pone.0297846

PMCID:: PMC10898740

Abstract Article PDF–2.8M

Select item 101916202.

Neuronal identity defines α-synuclein and tau toxicity

Roman Praschberger, Sabine Kuenen, Nils Schoovaerts, Natalie Kaempf, Jeevanjot Singh, Jasper Janssens, Jef Swerts, Eliana Nachman, Carles Calatayud, Stein Aerts, Suresh Poovathingal, Patrik Verstreken

Neuron. 2023 May 17; 111(10): 1577–1590.e11. doi: 10.1016/j.neuron.2023.02.033

PMCID:: PMC10191620

Abstract Article

Select item 99975703.

NDR kinase tricornered genetically interacts with Ccm3 and metabolic enzymes in Drosophila melanogaster tracheal development

Joshua Hudson, Sayantanee Paul, Alexey Veraksa, Amin Ghabrial, Kieran F Harvey, Carole Poon

G3 (Bethesda) 2023 Mar; 13(3): jkad013. Published online 2023 Jan 19. doi: 10.1093/g3journal/jkad013

PMCID:: PMC9997570

Abstract Article PDF–798K

Select item 97134314.

Transcriptome analysis of FOXO-dependent hypoxia gene expression identifies Hipk as a regulator of low oxygen tolerance in Drosophila

Kate Ding, Elizabeth C Barretto, Michael Johnston, Byoungchun Lee, Marco Gallo, Savraj S Grewal

G3 (Bethesda) 2022 Dec; 12(12): jkac263. Published online 2022 Oct 6. doi: 10.1093/g3journal/jkac263

PMCID:: PMC9713431

Abstract Article PDF–1.0M

Select item 92046035.

In Depth Exploration of the Alternative Proteome of Drosophila melanogaster

Bertrand Fabre, Sebastien A. Choteau, Carine Duboé, Carole Pichereaux, Audrey Montigny, Dagmara Korona, Michael J. Deery, Mylène Camus, Christine Brun, Odile Burlet-Schiltz, Steven Russell, Jean-Philippe Combier, Kathryn S. Lilley, Serge Plaza

Front Cell Dev Biol. 2022; 10: 901351. Published online 2022 May 26. doi: 10.3389/fcell.2022.901351

PMCID:: PMC9204603

Abstract Article PDF–2.1M

Select item 85753136.

Predicting novel candidate human obesity genes and their site of action by systematic functional screening in Drosophila

Neha Agrawal, Katherine Lawler, Catherine M. Davidson, Julia M. Keogh, Robert Legg, INTERVAL, Inês Barroso, I. Sadaf Farooqi, Andrea H. Brand

PLoS Biol. 2021 Nov; 19(11): e3001255. Published online 2021 Nov 8. doi: 10.1371/journal.pbio.3001255

PMCID:: PMC8575313

Abstract Article PDF–2.3M

Select item 69615787.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 60824018.

High-throughput functional analysis distinguishes pathogenic, nonpathogenic, and compensatory transcriptional changes in a neurodegenerative disorder

Ismael Al-Ramahi, Boxun Lu, Simone Di Paola, Kaifang Pang, Maria de Haro, Ivana Peluso, Tatiana Gallego-Flores, Nazish T. Malik, Kelly Erikson, Benjamin A. Bleiberg, Matthew Avalos, George Fan, Laura Elizabeth Rivers, Andrew M. Laitman, Javier R. Diaz-García, Marc Hild, James Palacino, Zhandong Liu, Diego L. Medina, Juan Botas

Cell Syst. Author manuscript; available in PMC 2019 Jul 25.

Published in final edited form as: Cell Syst. 2018 Jul 25; 7(1): 28–40.e4. Published online 2018 Jun 20. doi: 10.1016/j.cels.2018.05.010

PMCID:: PMC6082401

Abstract Article PDF–2.3M

Select item 60786049.

Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson’s disease

Md Shariful Islam, Hendrik Nolte, Wright Jacob, Anna B. Ziegler, Stefanie Pütz, Yael Grosjean, Karolina Szczepanowska, Aleksandra Trifunovic, Thomas Braun, Hermann Heumann, Rolf Heumann, Bernhard Hovemann, Darren J. Moore, Marcus Krüger

Hum Mol Genet. 2016 Dec 15; 25(24): 5365–5382. Published online 2016 Oct 29. doi: 10.1093/hmg/ddw352

PMCID:: PMC6078604

Abstract Article PDF–1.9M

Select item 593136910.

A Whole Animal Platform to Advance A Clinical Kinase Inhibitor Into New Disease Space

Masahiro Sonoshita, Alex P. Scopton, Peter M-U. Ung, Matthew A. Murray, Lisa Silber, Andres Y. Maldonado, Alexander Real, Avner Schlessinger, Ross L. Cagan, Arvin C. Dar

Nat Chem Biol. Author manuscript; available in PMC 2018 Jul 22.

Published in final edited form as: Nat Chem Biol. 2018 Mar; 14(3): 291–298. Published online 2018 Jan 22. doi: 10.1038/nchembio.2556

PMCID:: PMC5931369

Abstract Article PDF–2.9M

Select item 582185011.

Basal condensation of Numb and Pon complex via phase transition during Drosophila neuroblast asymmetric division

Zelin Shan, Yuting Tu, Ying Yang, Ziheng Liu, Menglong Zeng, Huisha Xu, Jiafu Long, Mingjie Zhang, Yu Cai, Wenyu Wen

Nat Commun. 2018; 9: 737. Published online 2018 Feb 21. doi: 10.1038/s41467-018-03077-3

PMCID:: PMC5821850

Abstract Article PDF–6.9M

Select item 570780512.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900213.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 506892714.

A Drosophila LexA Enhancer-Trap Resource for Developmental Biology and Neuroendocrine Research

Lutz Kockel, Lutfi M. Huq, Anika Ayyar, Emma Herold, Elle MacAlpine, Madeline Logan, Christina Savvides, Grace E. S. Kim, Jiapei Chen, Theresa Clark, Trang Duong, Vahid Fazel-Rezai, Deanna Havey, Samuel Han, Ravi Jagadeesan, Eun Soo Jackie Kim, Diane Lee, Kaelina Lombardo, Ida Piyale, Hansen Shi, Lydia Stahr, Dana Tung, Uriel Tayvah, Flora Wang, Ja-Hon Wang, Sarah Xiao, Sydni M. Topper, Sangbin Park, Cheryl Rotondo, Anne E. Rankin, Townley W. Chisholm, Seung K. Kim

G3 (Bethesda) 2016 Oct; 6(10): 3017–3026. Published online 2016 Aug 15. doi: 10.1534/g3.116.031229

PMCID:: PMC5068927

Abstract Article PDF–2.0M

Select item 464270915.

Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi

Benjamin E. Housden, Alexander J. Valvezan, Colleen Kelley, Richelle Sopko, Yanhui Hu, Charles Roesel, Shuailiang Lin, Michael Buckner, Rong Tao, Bahar Yilmazel, Stephanie E. Mohr, Brendan D. Manning, Norbert Perrimon

Sci Signal. Author manuscript; available in PMC 2016 Mar 8.

Published in final edited form as: Sci Signal. 2015; 8(393): rs9. Published online 2015 Sep 8. doi: 10.1126/scisignal.aab3729

PMCID:: PMC4642709

Abstract Article PDF–959K

Select item 457069716.

Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach

Flavio Pazos Obregón, Cecilia Papalardo, Sebastián Castro, Gustavo Guerberoff, Rafael Cantera

BMC Genomics. 2015; 16(1): 694. Published online 2015 Sep 15. doi: 10.1186/s12864-015-1888-3

PMCID:: PMC4570697

Abstract Article PDF–2.0M

Select item 452833017.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832918.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

Select item 435288719.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114

PMCID:: PMC4352887

Abstract Article PDF–1022K

Select item 427152720.

Phylostratigraphic Bias Creates Spurious Patterns of Genome Evolution

Bryan A. Moyers, Jianzhi Zhang

Mol Biol Evol. 2015 Jan 1; 32(1): 258–267. Published online 2014 Oct 13. doi: 10.1093/molbev/msu286

Correction in:: Mol Biol Evol. 2016 Nov; 33(11): 3031.

PMCID:: PMC4271527

Abstract Article PDF–618K

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