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Select item 109177971.

A single-cell atlas of Drosophila trachea reveals glycosylation-mediated Notch signaling in cell fate specification

Yue Li, Tianfeng Lu, Pengzhen Dong, Jian Chen, Qiang Zhao, Yuying Wang, Tianheng Xiao, Honggang Wu, Quanyi Zhao, Hai Huang

Nat Commun. 2024; 15: 2019. Published online 2024 Mar 6. doi: 10.1038/s41467-024-46455-w

PMCID:: PMC10917797

Abstract Article PDF–5.3M

Select item 107633632.

Tissue-specific RNA Polymerase II promoter-proximal pause release and burst kinetics in a Drosophila embryonic patterning network

George Hunt, Roshan Vaid, Sergei Pirogov, Alexander Pfab, Christoph Ziegenhain, Rickard Sandberg, Johan Reimegård, Mattias Mannervik

Genome Biol. 2024; 25: 2. Published online 2024 Jan 2. doi: 10.1186/s13059-023-03135-0

PMCID:: PMC10763363

Abstract Article PDF–9.8M

Select item 105922033.

Chromatin accessibility in the Drosophila embryo is determined by transcription factor pioneering and enhancer activation

Kaelan J. Brennan, Melanie Weilert, Sabrina Krueger, Anusri Pampari, Hsiao-yun Liu, Ally W.H. Yang, Jason A. Morrison, Timothy R. Hughes, Christine A. Rushlow, Anshul Kundaje, Julia Zeitlinger

Dev Cell. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Dev Cell. 2023 Oct 9; 58(19): 1898–1916.e9. Published online 2023 Aug 8. doi: 10.1016/j.devcel.2023.07.007

PMCID:: PMC10592203

Abstract Article PDF–3.4M

Select item 105904264.

3D chromatin interactions involving Drosophila insulators are infrequent but preferential and arise before TADs and transcription

Olivier Messina, Flavien Raynal, Julian Gurgo, Jean-Bernard Fiche, Vera Pancaldi, Marcelo Nollmann

Nat Commun. 2023; 14: 6678. Published online 2023 Oct 21. doi: 10.1038/s41467-023-42485-y

PMCID:: PMC10590426

Abstract Article PDF–3.6M

Select item 104153025.

Stepwise modifications of transcriptional hubs link pioneer factor activity to a burst of transcription

Chun-Yi Cho, Patrick H. O’Farrell

Nat Commun. 2023; 14: 4848. Published online 2023 Aug 10. doi: 10.1038/s41467-023-40485-6

PMCID:: PMC10415302

Abstract Article PDF–9.8M

Select item 103681866.

Genome organization controls transcriptional dynamics during development

Philippe J. Batut, Xin Yang Bing, Zachary Sisco, João Raimundo, Michal Levo, Michael S. Levine

Science. Author manuscript; available in PMC 2023 Jul 25.

Published in final edited form as: Science. 2022 Feb 4; 375(6580): 566–570. Published online 2022 Feb 3. doi: 10.1126/science.abi7178

PMCID:: PMC10368186

Abstract Article PDF–1.4M

Select item 100254497.

Continuous transcriptome analysis reveals novel patterns of early gene expression in Drosophila embryos

J. Eduardo Pérez-Mojica, Lennart Enders, Joseph Walsh, Kin H. Lau, Adelheid Lempradl

Cell Genom. 2023 Mar 8; 3(3): 100265. Published online 2023 Feb 15. doi: 10.1016/j.xgen.2023.100265

PMCID:: PMC10025449

Abstract Article PDF–2.6M

Select item 99414998.

Dynamic interplay between non-coding enhancer transcription and gene activity in development

Kota Hamamoto, Yusuke Umemura, Shiho Makino, Takashi Fukaya

Nat Commun. 2023; 14: 826. Published online 2023 Feb 20. doi: 10.1038/s41467-023-36485-1

PMCID:: PMC9941499

Abstract Article PDF–3.8M

Select item 99178899.

Mechanisms of Interaction between Enhancers and Promoters in Three Drosophila Model Systems

Olga Kyrchanova, Vladimir Sokolov, Pavel Georgiev

Int J Mol Sci. 2023 Feb; 24(3): 2855. Published online 2023 Feb 2. doi: 10.3390/ijms24032855

PMCID:: PMC9917889

Abstract Article PDF–2.2M

Select item 981687510.

The Drosophila embryo as a tabula rasa for the epigenome

Kami Ahmad, Steven Henikoff

Fac Rev. 2022; 11: 40. Published online 2022 Dec 23. doi: 10.12703/r/11-40

PMCID:: PMC9816875

Abstract Article PDF–2.0M

Select item 981240711.

Germline/soma distinction in Drosophila embryos requires regulators of zygotic genome activation

Megan M Colonnetta, Paul Schedl, Girish Deshpande

eLife. 2023; 12: e78188. Published online 2023 Jan 4. doi: 10.7554/eLife.78188

PMCID:: PMC9812407

Abstract Article PDF–21M

Select item 943415612.

Premature translation of the Drosophila zygotic genome activator Zelda is not sufficient to precociously activate gene expression

Elizabeth D Larson, Hideyuki Komori, Zoe A Fitzpatrick, Samuel D Krabbenhoft, Cheng-Yu Lee, Melissa Harrison

G3 (Bethesda) 2022 Sep; 12(9): jkac159. Published online 2022 Jul 25. doi: 10.1093/g3journal/jkac159

PMCID:: PMC9434156

Abstract Article PDF–1.8M

Select item 933649513.

Chromatin and transcriptomic profiling uncover dysregulation of the Tip60 HAT/HDAC2 epigenomic landscape in the neurodegenerative brain

Mariah Beaver, Bhanu Chandra Karisetty, Haolin Zhang, Akanksha Bhatnagar, Ellen Armour, Visha Parmar, Reshma Brown, Merry Xiang, Felice Elefant

Epigenetics. 2022; 17(7): 786–807. Published online 2021 Aug 9. doi: 10.1080/15592294.2021.1959742

PMCID:: PMC9336495

Abstract Article PDF–3.5M

Select item 918323314.

Notch-dependent and -independent transcription are modulated by tissue movements at gastrulation

Julia Falo-Sanjuan, Sarah Bray

eLife. 2022; 11: e73656. Published online 2022 May 18. doi: 10.7554/eLife.73656

PMCID:: PMC9183233

Abstract Article PDF–7.1M

Select item 897555115.

Synthetic reconstruction of the hunchback promoter specifies the role of Bicoid, Zelda and Hunchback in the dynamics of its transcription

Gonçalo Fernandes, Huy Tran, Maxime Andrieu, Youssoupha Diaw, Carmina Perez Romero, Cécile Fradin, Mathieu Coppey, Aleksandra M Walczak, Nathalie Dostatni

eLife. 2022; 11: e74509. Published online 2022 Apr 1. doi: 10.7554/eLife.74509

PMCID:: PMC8975551

Abstract Article PDF–5.0M

Select item 889746516.

The control of transcriptional memory by stable mitotic bookmarking

Maëlle Bellec, Jérémy Dufourt, George Hunt, Hélène Lenden-Hasse, Antonio Trullo, Amal Zine El Aabidine, Marie Lamarque, Marissa M. Gaskill, Heloïse Faure-Gautron, Mattias Mannervik, Melissa M. Harrison, Jean-Christophe Andrau, Cyril Favard, Ovidiu Radulescu, Mounia Lagha

Nat Commun. 2022; 13: 1176. Published online 2022 Mar 4. doi: 10.1038/s41467-022-28855-y

PMCID:: PMC8897465

Abstract Article PDF–3.5M

Select item 888344317.

Single‐cell RNA sequencing of motoneurons identifies regulators of synaptic wiring in Drosophila embryos

Jessica Velten, Xuefan Gao, Patrick Van Nierop y Sanchez, Katrin Domsch, Rashi Agarwal, Lena Bognar, Malte Paulsen, Lars Velten, Ingrid Lohmann

Mol Syst Biol. 2022 Mar; 18(3): e10255. Published online 2022 Feb 28. doi: 10.15252/msb.202110255

PMCID:: PMC8883443

Abstract Article PDF–3.0M

Select item 881529718.

GAGA factor: a multifunctional pioneering chromatin protein

Darya Chetverina, Maksim Erokhin, Paul Schedl

Cell Mol Life Sci. 2021 May; 78(9): 4125–4141. Published online 2021 Feb 2. doi: 10.1007/s00018-021-03776-z

PMCID:: PMC8815297

Abstract Article PDF–3.5M

Select item 866448619.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349