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Select item 111926811.

SETDB1 deletion causes DNA demethylation and upregulation of multiple zinc-finger genes

Yong-Kook Kang, Jaemin Eom, Byungkuk Min, Jung Sun Park

Mol Biol Rep. 2024; 51(1): 778. Published online 2024 Jun 21. doi: 10.1007/s11033-024-09703-2

PMCID:: PMC11192681

Abstract Article PDF–3.1M

Select item 111481842.

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek

Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x

PMCID:: PMC11148184

Abstract Article PDF–8.1M

Select item 109143113.

Cytoplasmic localization of SETDB1-induced Warburg effect via c-MYC-LDHA axis enhances migration and invasion in breast carcinoma

Wenlin Yang, Yingze Wei, Ting Wang, Ying Xu, Xiaoxia Jin, Hongyan Qian, Shuyun Yang, Song He

Int J Mol Med. 2024 Apr; 53(4): 40. Published online 2024 Feb 28. doi: 10.3892/ijmm.2024.5364

PMCID:: PMC10914311

Abstract Article PDF–9.6M

Select item 108402444.

SETDB1 promotes progression through upregulation of SF3B4 expression and regulates the immunity in ovarian cancer

Hongjuan Yang, Lei Sui, Cuicui Cai, Huijun Chu, Yuchao Diao

J Ovarian Res. 2024; 17: 34. Published online 2024 Feb 5. doi: 10.1186/s13048-024-01358-8

PMCID:: PMC10840244

Abstract Article PDF–2.9M

Select item 106449625.

Evidence of a synthetic lethality interaction between SETDB1 histone methyltransferase and CHD4 chromatin remodeling protein in a triple negative breast cancer cell line

M.S. Moraes-Almeida, M.C. Sogayar, M.A.A. Demasi

Braz J Med Biol Res. 2023; 56: e12854. Published online 2023 Nov 13. doi: 10.1590/1414-431X2023e12854

PMCID:: PMC10644962

Abstract Article PDF–1.0M

Select item 105586706.

SETDB1 Methylates MCT1 Promoting Tumor Progression by Enhancing the Lactate Shuttle

Xiaowei She, Qi Wu, Zejun Rao, Da Song, Changsheng Huang, Shengjie Feng, Anyi Liu, Lang Liu, Kairui Wan, Xun Li, Chengxin Yu, Cheng Qiu, Xuelai Luo, Junbo Hu, Guihua Wang, Feng Xu, Li Sun

Adv Sci (Weinh) 2023 Oct; 10(28): 2301871. Published online 2023 Aug 4. doi: 10.1002/advs.202301871

PMCID:: PMC10558670

Abstract Article PDF–4.4M

Select item 104541457.

Children with Chronic Immune Thrombocytopenia Exhibit High Expression of Human Endogenous Retroviruses TRIM28 and SETDB1

Pier-Angelo Tovo, Ilaria Galliano, Emilia Parodi, Cristina Calvi, Stefano Gambarino, Francesco Licciardi, Maddalena Dini, Paola Montanari, Margherita Branca, Ugo Ramenghi, Massimiliano Bergallo

Genes (Basel) 2023 Aug; 14(8): 1569. Published online 2023 Aug 1. doi: 10.3390/genes14081569

PMCID:: PMC10454145

Abstract Article PDF–2.0M

Select item 104035758.

SETDB1 tumour suppressor roles in near-haploid mesothelioma involve TP53

Mengting Xu, Yuqing Tu, Wenhui Bi, Meijun Z. Lundberg, Isabella Klooster, Jonathan A. Fletcher, Wen-Bin Ou

Br J Cancer. 2023 Aug 24; 129(3): 531–540. Published online 2023 Jun 27. doi: 10.1038/s41416-023-02330-x

PMCID:: PMC10403575

Abstract Article PDF–1.5M

Select item 102374229.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1018265410.

The pattern of histone H3 epigenetic posttranslational modifications is regulated by the VRK1 chromatin kinase

Eva Monte-Serrano, Patricia Morejón-García, Ignacio Campillo-Marcos, Aurora Campos-Díaz, Elena Navarro-Carrasco, Pedro A. Lazo

Epigenetics Chromatin. 2023; 16: 18. Published online 2023 May 13. doi: 10.1186/s13072-023-00494-7

PMCID:: PMC10182654

Abstract Article PDF–3.1M

Select item 1012173911.

SETDB1: a perspective into immune cell function and cancer immunotherapy

Eleanor Johnson, Kiarash Salari, Shujie Yang

Immunology. Author manuscript; available in PMC 2024 May 1.

Published in final edited form as: Immunology. 2023 May; 169(1): 3–12. Published online 2022 Dec 21. doi: 10.1111/imm.13619

PMCID:: PMC10121739

Abstract Article PDF–1.1M

Select item 1005111612.

Pregnancy Is Associated with Impaired Transcription of Human Endogenous Retroviruses and of TRIM28 and SETDB1, Particularly in Mothers Affected by Multiple Sclerosis

Pier-Angelo Tovo, Luca Marozio, Giancarlo Abbona, Cristina Calvi, Federica Frezet, Stefano Gambarino, Maddalena Dini, Chiara Benedetto, Ilaria Galliano, Massimiliano Bergallo

Viruses. 2023 Mar; 15(3): 710. Published online 2023 Mar 9. doi: 10.3390/v15030710

PMCID:: PMC10051116

Abstract Article PDF–3.8M

Select item 1000589813.

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA

Ellis G. Jaffray, Michael H. Tatham, Barbara Mojsa, Magda Liczmanska, Alejandro Rojas-Fernandez, Yili Yin, Graeme Ball, Ronald T. Hay

J Cell Biol. 2023 Apr 3; 222(4): e202201027. Published online 2023 Feb 28. doi: 10.1083/jcb.202201027

PMCID:: PMC10005898

Abstract Article PDF–6.7M

Select item 980149414.

Histone H3K9 Methyltransferase SETDB1 Augments Invadopodia Formation to Promote Tumor Metastasis

Shuhei Ueshima, Jia Fang

Oncogene. Author manuscript; available in PMC 2022 Dec 30.

Published in final edited form as: Oncogene. 2022 Jun; 41(24): 3370–3380. Published online 2022 May 11. doi: 10.1038/s41388-022-02345-3

PMCID:: PMC9801494

Abstract Article PDF–5.5M

Select item 976969815.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 975346916.

Structure and functional mapping of the KRAB‐KAP1 repressor complex

Guido A Stoll, Ninoslav Pandiloski, Christopher H Douse, Yorgo Modis

EMBO J. 2022 Dec; 41(24): e111179. Published online 2022 Nov 7. doi: 10.15252/embj.2022111179

PMCID:: PMC9753469

Abstract Article PDF–17M

Select item 945636317.

TRAF4 Promotes the Proliferation of Glioblastoma by Stabilizing SETDB1 to Activate the AKT Pathway

Hongyu Gu, Shunqin Zhu, Cheng Peng, Zekun Wei, Yang Shen, Chaoyu Yuan, He Yang, Hongjuan Cui, Liqun Yang

Int J Mol Sci. 2022 Sep; 23(17): 10161. Published online 2022 Sep 5. doi: 10.3390/ijms231710161

PMCID:: PMC9456363

Abstract Article PDF–50M

Select item 935712718.

SETDB1 Restrains Endogenous Retrovirus Expression and Antitumor Immunity during Radiotherapy

Dong Pan, Xuhui Bao, Mengjie Hu, Meng Jiao, Fang Li, Chuan-Yuan Li

Cancer Res. 2022 Aug 3; 82(15): 2748–2760. Published online 2022 May 31. doi: 10.1158/0008-5472.CAN-21-3523

PMCID:: PMC9357127

Abstract Article PDF–1.5M

Select item 934857619.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 927928520.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

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