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Items: 1 to 20 of 115

1.
The ST2+ Treg/amphiregulin axis protects from immune-mediated hepatitis
Selina Wachtendorf, Fitriasari Jonin, Aaron Ochel, Fabian Heinrich, Astrid M. Westendorf, Gisa Tiegs, Katrin Neumann
Front Immunol. 2024; 15: 1351405. Published online 2024 Mar 20. doi: 10.3389/fimmu.2024.1351405
PMCID:
PMC10987816
ArticlePDF–5.7M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
ArticlePDF–4.8M
3.
Amphiregulin normalizes altered circuit connectivity for social dominance of the CRTC3 knockout mouse
Ji-Seon Park, Hwon Heo, Min-Seok Kim, Seung-Eun Lee, Sukyoung Park, Ki-Hyun Kim, Young-Ho Kang, Je Seong Kim, Young Hoon Sung, Woo Hyun Shim, Dong-Hou Kim, Youngsup Song, Seung-Yong Yoon
Mol Psychiatry. 2023; 28(11): 4655–4665. Published online 2023 Sep 20. doi: 10.1038/s41380-023-02258-x
PMCID:
PMC10914624
ArticlePDF–3.0M
4.
Keratinocytes-specific SOX2 overexpression suppressed pressure ulcer formation following cutaneous I/R injury via enhancement of amphiregulin production
Yuta Inoue, Akihiko Uchiyama, Syahla Nisaa Amalia, Mai Ishikawa, Keiji Kosaka, Akiko Sekiguchi, Sachiko Ogino, Yoko Yokoyama, Ryoko Torii, Mari Hosoi, Ryoko Akai, Takao Iwawaki, Maria I. Morasso, Sei-ichiro Motegi
J Invest Dermatol. Author manuscript; available in PMC 2025 Jan 1.
Published in final edited form as: J Invest Dermatol. 2024 Jan; 144(1): 142–151.e5. Published online 2023 Jul 28. doi: 10.1016/j.jid.2023.06.202
PMCID:
PMC10822028
ArticlePDF–1.8M
5.
The amphiregulin/EGFR axis has limited contribution in controlling autoimmune diabetes
Arielle Raugh, Yi Jing, Matthew L. Bettini, Maria Bettini
Sci Rep. 2023; 13: 18653. Published online 2023 Oct 30. doi: 10.1038/s41598-023-45738-4
PMCID:
PMC10616065
ArticlePDF–1.6M
6.
TRIM28 modulates nuclear receptor signaling to regulate uterine function
Rong Li, Tianyuan Wang, Ryan M. Marquardt, John P. Lydon, San-Pin Wu, Francesco J. DeMayo
Nat Commun. 2023; 14: 4605. Published online 2023 Aug 1. doi: 10.1038/s41467-023-40395-7
PMCID:
PMC10393996
ArticlePDF–11M
7.
Neuropeptide regulation of non-redundant ILC2 responses at barrier surfaces
Amy M. Tsou, Hiroshi Yano, Christopher N. Parkhurst, Tanel Mahlakõiv, Coco Chu, Wen Zhang, Zhengxiang He, Katja J. Jarick, Connie Zhong, Gregory G. Putzel, Mai Hatazaki, JRI IBD Live Cell Bank Consortium, Ivo C. Lorenz, David Andrew, Paul Balderes, Christoph S. N. Klose, Sergio A. Lira, David Artis
Nature. Author manuscript; available in PMC 2023 Nov 2.
Published in final edited form as: Nature. 2022 Nov; 611(7937): 787–793. Published online 2022 Nov 2. doi: 10.1038/s41586-022-05297-6
PMCID:
PMC10225046
ArticlePDF–5.5M
8.
Droplet-based forward genetic screening of astrocyte–microglia cross-talk
Michael A. Wheeler, Iain C. Clark, Hong-Gyun Lee, Zhaorong Li, Mathias Linnerbauer, Joseph M. Rone, Manon Blain, Camilo Faust Akl, Gavin Piester, Federico Giovannoni, Marc Charabati, Joon-Hyuk Lee, Yoon-Chul Kye, Joshua Choi, Liliana M. Sanmarco, Lena Srun, Elizabeth N. Chung, Lucas E. Flausino, Brian M. Andersen, Veit Rothhammer, Hiroshi Yano, Tomer Illouz, Stephanie E. J. Zandee, Carolin Daniel, David Artis, Marco Prinz, Adam R. Abate, Vijay K. Kuchroo, Jack P. Antel, Alexandre Prat, Francisco J. Quintana
Science. Author manuscript; available in PMC 2023 Apr 10.
Published in final edited form as: Science. 2023 Mar 10; 379(6636): 1023–1030. Published online 2023 Mar 9. doi: 10.1126/science.abq4822
PMCID:
PMC10066924
ArticlePDF–1.6M
9.
Bulk and mosaic deletions of Egfr reveal regionally defined gliogenesis in the developing mouse forebrain
Xuying Zhang, Guanxi Xiao, Caroline Johnson, Yuheng Cai, Zachary K. Horowitz, Christine Mennicke, Robert Coffey, Mansoor Haider, David Threadgill, Rebecca Eliscu, Michael C. Oldham, Alon Greenbaum, H. Troy Ghashghaei
iScience. 2023 Mar 17; 26(3): 106242. Published online 2023 Feb 20. doi: 10.1016/j.isci.2023.106242
PMCID:
PMC10006693
ArticlePDF–7.6M
10.
Role of MR1-driven signals and amphiregulin on the recruitment and repair function of MAIT cells during skin wound healing
Anastasia du Halgouet, Aurélie Darbois, Mansour Alkobtawi, Martin Mestdagh, Aurélia Alphonse, Virginie Premel, Thomas Yvorra, Ludovic Colombeau, Raphaël Rodriguez, Dietmar Zaiss, Yara El Morr, Hélène Bugaut, François Legoux, Laetitia Perrin, Selim Aractingi, Rachel Golub, Olivier Lantz, Marion Salou
Immunity. 2023 Jan 10; 56(1): 78–92.e6. doi: 10.1016/j.immuni.2022.12.004
PMCID:
PMC9839364
Article
11.
Regulation of the alveolar regenerative niche by amphiregulin-producing regulatory T cells
Katherine A. Kaiser, Lucas F. Loffredo, Kenia de los Santos-Alexis, Olivia R. Ringham, Nicholas Arpaia
J Exp Med. 2023 Mar 6; 220(3): e20221462. Published online 2022 Dec 19. doi: 10.1084/jem.20221462
PMCID:
PMC9767680
ArticlePDF–7.9M
12.
Downregulation of amphiregulin improves cardiac hypertrophy via attenuating oxidative stress and apoptosis
Mingyue Ji, Yun Liu, Zhi Zuo, Cheng Xu, Li Lin, Yong Li
Biol Direct. 2022; 17: 21. Published online 2022 Aug 22. doi: 10.1186/s13062-022-00334-w
PMCID:
PMC9394079
ArticlePDF–6.2M
13.
EGFR-mediated activation of adipose tissue macrophages promotes obesity and insulin resistance
Shirong Cao, Yu Pan, Jiaqi Tang, Andrew S. Terker, Juan Pablo Arroyo Ornelas, Guan-nan Jin, Yinqiu Wang, Aolei Niu, Xiaofeng Fan, Suwan Wang, Raymond C. Harris, Ming-Zhi Zhang
Nat Commun. 2022; 13: 4684. Published online 2022 Aug 10. doi: 10.1038/s41467-022-32348-3
PMCID:
PMC9365849
ArticlePDF–5.5M
14.
Group 3 innate lymphocytes make a distinct contribution to type 17 immunity in bladder defence
Alexandra M. Riding, Kevin W. Loudon, Andrew Guo, John R. Ferdinand, Laurence S.C. Lok, Nathan Richoz, Andrew Stewart, Tomas Castro-Dopico, Zewen Kelvin Tuong, Remi Fiancette, Georgina S. Bowyer, Aaron Fleming, Eleanor S. Gillman, Ondrej Suchanek, Krishnaa T. Mahbubani, Kourosh Saeb-Parsy, David Withers, Gordan Dougan, Simon Clare, Menna R. Clatworthy
iScience. 2022 Jul 15; 25(7): 104660. Published online 2022 Jun 22. doi: 10.1016/j.isci.2022.104660
PMCID:
PMC9283510
ArticlePDF–6.4M
15.
Loss of Amphiregulin drives inflammation and endothelial apoptosis in pulmonary hypertension
Jonathan Florentin, Jingsi Zhao, Yi-Yin Tai, Wei Sun, Lee L Ohayon, Scott P O’Neil, Anagha Arunkumar, Xinyi Zhang, Jianhui Zhu, Yassmin Al Aaraj, Annie Watson, John Sembrat, Mauricio Rojas, Stephen Y Chan, Partha Dutta
Life Sci Alliance. 2022 Nov; 5(11): e202101264. Published online 2022 Jun 22. doi: 10.26508/lsa.202101264
PMCID:
PMC9218345
ArticlePDF–2.4M
16.
Microglial-stimulation of glioma invasion involves the EGFR ligand amphiregulin
Salvatore J. Coniglio, Jeffrey E. Segall
PLoS One. 2021; 16(11): e0260252. Published online 2021 Nov 29. doi: 10.1371/journal.pone.0260252
PMCID:
PMC8629255
ArticlePDF–1.2M
17.
Signaling through retinoic acid receptors is essential for mammalian uterine receptivity and decidualization
Yan Yin, Meade E. Haller, Sangappa B. Chadchan, Ramakrishna Kommagani, Liang Ma
JCI Insight. 2021 Sep 8; 6(17): e150254. Published online 2021 Sep 8. doi: 10.1172/jci.insight.150254
PMCID:
PMC8492326
ArticlePDF–3.4M
18.
EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells
Suyasha Roy, Zaigham Abbas Rizvi, Alexander J. Clarke, Felicity Macdonald, Abhaydeep Pandey, Dietmar Martin Werner Zaiss, Anna Kathrina Simon, Amit Awasthi
Nat Commun. 2021; 12: 3182. Published online 2021 Jun 1. doi: 10.1038/s41467-021-23042-x
PMCID:
PMC8169867
ArticlePDF–4.8M
19.
Targeting autocrine amphiregulin robustly and reproducibly inhibits ovarian cancer in a syngeneic model: roles for wildtype p53
Moshit Lindzen, Soma Ghosh, Ashish Noronha, Diana Drago, Nishanth Belugali Nataraj, Orith Leitner, Silvia Carvalho, Einav Zmora, Stav Sapoznik, Keren Bahar Shany, Keren Levanon, Dan Aderka, Belinda Sánchez Ramírez, Maik Dahlhoff, Iain McNeish, Yosef Yarden
Oncogene. 2021; 40(21): 3665–3679. Published online 2021 Apr 30. doi: 10.1038/s41388-021-01784-8
PMCID:
PMC8154589
ArticlePDF–3.4M
20.
Dysregulation of Amphiregulin stimulates the pathogenesis of cystic lymphangioma
Naofumi Yoshida, Seiji Yamamoto, Takeru Hamashima, Noriko Okuno, Naruho Okita, Shinjiro Horikawa, Masao Hayashi, Thanh Chung Dang, Quang Linh Nguyen, Koichi Nishiyama, Teruhiko Makino, Yoko Ishii, Kei Tomihara, Tadamichi Shimizu, Masabumi Shibuya, Makoto Noguchi, Masakiyo Sasahara
Proc Natl Acad Sci U S A. 2021 May 11; 118(19): e2019580118. Published online 2021 May 3. doi: 10.1073/pnas.2019580118
PMCID:
PMC8126796
ArticlePDF–2.4M

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