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Select item 113836061.

Iron capture through CD71 drives perinatal and tumor-associated Treg expansion

Ilenia Pacella, Alessandra Pinzon Grimaldos, Alessandra Rossi, Gloria Tucci, Marta Zagaglioni, Elena Potenza, Valeria Pinna, Ivano Rotella, Ilenia Cammarata, Valeria Cancila, Beatrice Belmonte, Claudio Tripodo, Giuseppe Pietropaolo, Chiara Di Censo, Giuseppe Sciumè, Valerio Licursi, Giovanna Peruzzi, Ylenia Antonucci, Silvia Campello, Francesca Guerrieri, Valerio Iebba, Rita Prota, Maria Di Chiara, Gianluca Terrin, Valerio De Peppo, Gian Luca Grazi, Vincenzo Barnaba, Silvia Piconese

JCI Insight. 2024 Aug 8; 9(15): e167967. Published online 2024 Jul 2. doi: 10.1172/jci.insight.167967

PMCID:: PMC11383606

Abstract Article PDF–1.9M

Select item 113825152.

NAT10-mediated ac⁴C acetylation of TFRC promotes sepsis-induced pulmonary injury through regulating ferroptosis

Pengcheng Xing, Minjie Zhou, Jian Sun, Donglian Wang, Weipeng Huang, Peng An

Mol Med. 2024; 30: 140. Published online 2024 Sep 9. doi: 10.1186/s10020-024-00912-w

PMCID:: PMC11382515

Abstract Article PDF–3.2M

Select item 113735993.

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway

Elena Prosdocimi, Veronica Carpanese, Luca Matteo Todesca, Tatiana Varanita, Magdalena Bachmann, Margherita Festa, Daniele Bonesso, Mireia Perez-Verdaguer, Andrea Carrer, Angelo Velle, Roberta Peruzzo, Silvia Muccioli, Davide Doni, Luigi Leanza, Paola Costantini, Frank Stein, Mandy Rettel, Antonio Felipe, Michael J. Edwards, Erich Gulbins, Laura Cendron, Chiara Romualdi, Vanessa Checchetto, Ildiko Szabo

Sci Adv. 2024 Sep 6; 10(36): eadn9361. Published online 2024 Sep 4. doi: 10.1126/sciadv.adn9361

PMCID:: PMC11373599

Abstract Article PDF–11M

Select item 113159294.

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex

Marisa Bedir, Emily Outwin, Rita Colnaghi, Lydia Bassett, Iga Abramowicz, Mark O’Driscoll

EMBO Rep. 2024 Aug; 25(8): 3432–3455. Published online 2024 Jun 28. doi: 10.1038/s44319-024-00184-9

PMCID:: PMC11315929

Abstract Article PDF–3.4M

Select item 113134095.

Xiujuan Shang, Hongdong Wang, Jin Gu, Xiaohui Zhao, Jing Zhang, Bohao Sun, Xinming Zhu

PeerJ. 2024; 12: e17842. Published online 2024 Aug 6. doi: 10.7717/peerj.17842

PMCID:: PMC11313409

Abstract Article PDF–25M

Select item 112099356.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 111073697.

The Plasmodium vivax MSP1P-19 is involved in binding of reticulocytes through interactions with the membrane proteins band3 and CD71

Shenghuan Zuo, Jiachen Lu, Yifan Sun, Jing Song, Su Han, Xin Feng, Eun-Taek Han, Yang Cheng

J Biol Chem. 2024 May; 300(5): 107285. Published online 2024 Apr 16. doi: 10.1016/j.jbc.2024.107285

PMCID:: PMC11107369

Abstract Article PDF–3.4M

Select item 110936118.

The secreted micropeptide C4orf48 enhances renal fibrosis via an RNA-binding mechanism

Jiayi Yang, Hongjie Zhuang, Jinhua Li, Ana B. Nunez-Nescolarde, Ning Luo, Huiting Chen, Andy Li, Xinli Qu, Qing Wang, Jinjin Fan, Xiaoyan Bai, Zhiming Ye, Bing Gu, Yue Meng, Xingyuan Zhang, Di Wu, Youyang Sia, Xiaoyun Jiang, Wei Chen, Alexander N. Combes, David J. Nikolic-Paterson, Xueqing Yu

J Clin Invest. 2024 May 15; 134(10): e178392. Published online 2024 Apr 16. doi: 10.1172/JCI178392

PMCID:: PMC11093611

Abstract Article PDF–25M

Select item 110327939.

Down-regulation of HLA class II and costimulatory CD86/B7-2 on circulating monocytes from melanoma patients

Selma Ugurel, Dario Uhlig, Claudia Pföhler, Wolfgang Tilgen, Dirk Schadendorf, Uwe Reinhold

Cancer Immunol Immunother. 2004 Jun; 53(6): 551–559. Published online 2004 Jan 16. doi: 10.1007/s00262-003-0489-1

PMCID:: PMC11032793

Abstract Article PDF–391K

Select item 1099027710.

ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication

Guy J. Pearson, Harriet V. Mears, Malgorzata Broncel, Ambrosius P. Snijders, David L. V. Bauer, Jeremy G. Carlton

Sci Adv. 2024 Apr 5; 10(14): eadl5012. Published online 2024 Apr 3. doi: 10.1126/sciadv.adl5012

PMCID:: PMC10990277

Abstract Article PDF–3.9M

Select item 1094570711.

Comparative interactome analysis of α-arrestin families in human and Drosophila

Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam

eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328

PMCID:: PMC10945707

Abstract Article PDF–2.8M

Select item 1093326712.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 1092752513.

Human transferrin receptor can mediate SARS-CoV-2 infection

Zhiyi Liao, Chaoming Wang, Xiaopeng Tang, Mengli Yang, Zilei Duan, Lei Liu, Shuaiyao Lu, Lei Ma, Ruomei Cheng, Gan Wang, Hongqi Liu, Shuo Yang, Jingwen Xu, Dawit Adisu Tadese, James Mwangi, Peter Muiruri Kamau, Zhiye Zhang, Lian Yang, Guoyang Liao, Xudong Zhao, Xiaozhong Peng, Ren Lai

Proc Natl Acad Sci U S A. 2024 Mar 5; 121(10): e2317026121. Published online 2024 Feb 26. doi: 10.1073/pnas.2317026121

PMCID:: PMC10927525

Abstract Article PDF–2.9M

Select item 1091686614.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 1085081815.

Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7

Joseph S. Baxter, Rachel Brough, Dragomir B. Krastev, Feifei Song, Sandhya Sridhar, Aditi Gulati, John Alexander, Theodoros I. Roumeliotis, Zuza Kozik, Jyoti S. Choudhary, Syed Haider, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord

Mol Oncol. 2024 Feb; 18(2): 369–385. Published online 2023 Oct 22. doi: 10.1002/1878-0261.13537

PMCID:: PMC10850818

Abstract Article PDF–2.7M

Select item 1083461616.

METTL3 regulates TFRC ubiquitination and ferroptosis through stabilizing NEDD4L mRNA to impact stroke

Wenjie Su, Xiang Yu, Shan Wang, Xu Wang, Zheng Dai, Yi Li

Cell Biol Toxicol. 2024; 40(1): 8. Published online 2024 Feb 2. doi: 10.1007/s10565-024-09844-x

PMCID:: PMC10834616

Abstract Article PDF–7.0M

Select item 1080928817.

Transferrin receptor levels and its rare variant are associated with human obesity

Jin Qiu, Zhiyin Zhang, Yepeng Hu, Yuhan Guo, Caizhi Liu, Yanru Chen, Dongmei Wang, Junlei Su, Sainan Wang, Mengshan Ni, Sainan Xu, Jian Yu, Tianhui Hu, Gaojie Song, Xinran Ma, Xuejiang Gu, Jiqiu Wang, Lingyan Xu

J Diabetes. 2024 Jan; 16(1): e13467. Published online 2023 Aug 30. doi: 10.1111/1753-0407.13467

PMCID:: PMC10809288

Abstract Article PDF–7.6M

Select item 1068833718.

SARS-CoV-2 NSP12 associates with TRiC and the P323L substitution acts as a host adaption

Muhannad Alruwaili, Stuart Armstrong, Tessa Prince, Maximillian Erdmann, David A. Matthews, Lisa Luu, Andrew Davidson, Waleed Aljabr, Julian A. Hiscox

J Virol. 2023 Nov; 97(11): e00424-23. Published online 2023 Nov 6. doi: 10.1128/jvi.00424-23

PMCID:: PMC10688337

Abstract Article PDF–2.2M

Select item 1061767319.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 1054568620.

Dysregulation of iron homeostasis by TfR-1 renders EZH2 wild type diffuse large B-cell lymphoma resistance to EZH2 inhibition

Lei Yu, Ya-fang Wang, Jian Xiao, Qian-qian Shen, Shuai-shuai Chi, Ying-lei Gao, Dong-ze Lin, Jian Ding, Yan-fen Fang, Yi Chen

Acta Pharmacol Sin. 2023 Oct; 44(10): 2113–2124. Published online 2023 May 25. doi: 10.1038/s41401-023-01097-4

PMCID:: PMC10545686

Abstract Article PDF–5.7M

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