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Select item 109535651.

Cfp1 Controls Cardiomyocyte Maturation by Modifying Histone H3K4me3 of Structural, Metabolic, and Contractile Related Genes

Changzhu Li, Yang Zhang, Jingling Shen, Hairong Bao, Yue Zhao, Desheng Li, Sijia Li, Yining Liu, Jiming Yang, Zhiwen Zhou, Kangyi Gao, Lexin Zhao, Yao Pei, Yanjie Lu, Zhenwei Pan, Benzhi Cai

Adv Sci (Weinh) 2024 Mar; 11(11): 2305992. Published online 2024 Jan 9. doi: 10.1002/advs.202305992

PMCID:: PMC10953565

Abstract Article PDF–5.8M

Select item 108979192.

Coordinated metabolic responses to cyclophilin D deletion in the developing heart

Gisela Beutner, Jonathan Ryan Burris, Michael P. Collins, Chaitanya A. Kulkarni, Sergiy M. Nadtochiy, Karen L. de Mesy Bentley, Ethan D. Cohen, Paul S. Brookes, George A. Porter, Jr.

iScience. 2024 Mar 15; 27(3): 109157. Published online 2024 Feb 9. doi: 10.1016/j.isci.2024.109157

PMCID:: PMC10897919

Abstract Article PDF–5.5M

Select item 108545023.

Investigation into Cardiac Myhc-α 334–352-Specific TCR Transgenic Mice Reveals a Role for Cytotoxic CD4 T Cells in the Development of Cardiac Autoimmunity

Meghna Sur, Mahima T. Rasquinha, Kiruthiga Mone, Chandirasegaran Massilamany, Ninaad Lasrado, Channabasavaiah Gurumurthy, Raymond A. Sobel, Jay Reddy

Cells. 2024 Feb; 13(3): 234. Published online 2024 Jan 26. doi: 10.3390/cells13030234

PMCID:: PMC10854502

Abstract Article PDF–11M

Select item 105456734.

The CREG1-FBXO27-LAMP2 axis alleviates diabetic cardiomyopathy by promoting autophagy in cardiomyocytes

Dan Liu, Ruinan Xing, Quanyu Zhang, Xiaoxiang Tian, Yanping Qi, Haixu Song, Yanxia Liu, Haibo Yu, Xiaolin Zhang, Quanmin Jing, Chenghui Yan, Yaling Han

Exp Mol Med. 2023 Sep; 55(9): 2025–2038. Published online 2023 Sep 1. doi: 10.1038/s12276-023-01081-2

PMCID:: PMC10545673

Abstract Article PDF–5.6M

Select item 104981465.

FAM122A Is Required for Mesendodermal and Cardiac Differentiation of Embryonic Stem Cells

Yun-Sheng Yang, Man-Hua Liu, Zhao-Wen Yan, Guo-Qiang Chen, Ying Huang

Stem Cells. 2023 Apr; 41(4): 354–367. Published online 2023 Jan 30. doi: 10.1093/stmcls/sxad008

PMCID:: PMC10498146

Abstract Article PDF–29M

Select item 104787536.

Lem2 is essential for cardiac development by maintaining nuclear integrity

Jacob A Ross, Nathaly Arcos-Villacis, Edmund Battey, Cornelis Boogerd, Constanza Avalos Orellana, Emilie Marhuenda, Pamela Swiatlowska, Didier Hodzic, Fabrice Prin, Tim Mohun, Norman Catibog, Olga Tapia, Larry Gerace, Thomas Iskratsch, Ajay M Shah, Matthew J Stroud

Cardiovasc Res. 2023 Aug; 119(11): 2074–2088. Published online 2023 Apr 17. doi: 10.1093/cvr/cvad061

PMCID:: PMC10478753

Abstract Article PDF–33M

Select item 104742707.

α-myosin heavy chain lactylation maintains sarcomeric structure and function and alleviates the development of heart failure

Naijin Zhang, Ying Zhang, Jiaqi Xu, Pengbo Wang, Boquan Wu, Saien Lu, Xinxin Lu, Shilong You, Xinyue Huang, Mohan Li, Yuanming Zou, Mengke Liu, Yuanhui Zhao, Guozhe Sun, Wenbin Wang, Danxi Geng, Jingwei Liu, Liu Cao, Yingxian Sun

Cell Res. 2023 Sep; 33(9): 679–698. Published online 2023 Jul 13. doi: 10.1038/s41422-023-00844-w

PMCID:: PMC10474270

Abstract Article PDF–14M

Select item 103904928.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 103078529.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 1002316110.

The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart

Valeria Taliani, Giulia Buonaiuto, Fabio Desideri, Adriano Setti, Tiziana Santini, Silvia Galfrè, Leonardo Schirone, Davide Mariani, Giacomo Frati, Valentina Valenti, Sebastiano Sciarretta, Emerald Perlas, Carmine Nicoletti, Antonio Musarò, Monica Ballarino

eLife. 2023; 12: e81360. Published online 2023 Mar 6. doi: 10.7554/eLife.81360

PMCID:: PMC10023161

Abstract Article PDF–4.8M

Select item 991873611.

Intrafusal-fiber LRP4 for muscle spindle formation and maintenance in adult and aged animals

Rangjuan Cao, Peng Chen, Hongsheng Wang, Hongyang Jing, Hongsheng Zhang, Guanglin Xing, Bin Luo, Jinxiu Pan, Zheng Yu, Wen-Cheng Xiong, Lin Mei

Nat Commun. 2023; 14: 744. Published online 2023 Feb 10. doi: 10.1038/s41467-023-36454-8

PMCID:: PMC9918736

Abstract Article PDF–4.0M

Select item 967555612.

DIO3 protects against thyrotoxicosis-derived cranio-encephalic and cardiac congenital abnormalities

M. Elena Martinez, Ilka Pinz, Marilena Preda, Christine R. Norton, Thomas Gridley, Arturo Hernandez

JCI Insight. 2022 Nov 8; 7(21): e161214. Published online 2022 Nov 8. doi: 10.1172/jci.insight.161214

PMCID:: PMC9675556

Abstract Article PDF–3.9M

Select item 956419213.

PGC-1α4 Interacts with REST to Upregulate Neuronal Genes and Augment Energy Consumption in Developing Cardiomyocytes

Tomi Tuomainen, Nikolay Naumenko, Maija Mutikainen, Anastasia Shakirzyanova, Sarah Sczelecki, Jennifer L. Estall, Jorge L. Ruas, Pasi Tavi

Cells. 2022 Oct; 11(19): 2944. Published online 2022 Sep 20. doi: 10.3390/cells11192944

PMCID:: PMC9564192

Abstract Article PDF–3.2M

Select item 954690614.

Vascular smooth muscle RhoA counteracts abdominal aortic aneurysm formation by modulating MAP4K4 activity

Md Rasel Molla, Akio Shimizu, Masahiro Komeno, Nor Idayu A. Rahman, Joanne Ern Chi Soh, Le Kim Chi Nguyen, Mahbubur Rahman Khan, Wondwossen Wale Tesega, Si Chen, Xiaoling Pang, Miki Tanaka-Okamoto, Noriyuki Takashima, Akira Sato, Tomoaki Suzuki, Hisakazu Ogita

Commun Biol. 2022; 5: 1071. Published online 2022 Oct 7. doi: 10.1038/s42003-022-04042-z

PMCID:: PMC9546906

Abstract Article PDF–5.3M

Select item 938242515.

Cmarr/miR-540-3p axis promotes cardiomyocyte maturation transition by orchestrating Dtna expression

Yukang Wu, Xudong Guo, Tong Han, Ke Feng, Peng Zhang, Yanxin Xu, Yiwei Yang, Yuchen Xia, Yang Chen, Jiajie Xi, Huangtian Yang, Xiaoping Wan, Jiuhong Kang

Mol Ther Nucleic Acids. 2022 Sep 13; 29: 481–497. Published online 2022 Jul 31. doi: 10.1016/j.omtn.2022.07.022

PMCID:: PMC9382425

Abstract Article PDF–5.0M

Select item 928237816.

Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model

Anna Axelsson Raja, Hiroko Wakimoto, Daniel M. DeLaughter, Daniel Reichart, Joshua Gorham, David A. Conner, Mingyue Lun, Clemens K. Probst, Norihiko Sakai, Rachel S. Knipe, Sydney B. Montesi, Barry Shea, Leonard P. Adam, Leslie A. Leinwand, William Wan, Esther Sue Choi, Eric L. Lindberg, Giannino Patone, Michela Noseda, Norbert Hübner, Christine E. Seidman, Andrew M. Tager, J. G. Seidman, Carolyn Y. Ho

Proc Natl Acad Sci U S A. 2022 Jul 12; 119(28): e2204174119. Published online 2022 Jul 5. doi: 10.1073/pnas.2204174119

PMCID:: PMC9282378

Abstract Article PDF–2.2M

Select item 911817517.

Embryo-scale, single cell spatial transcriptomics

Sanjay R. Srivatsan, Mary C. Regier, Eliza Barkan, Jennifer M. Franks, Jonathan S. Packer, Parker Grosjean, Madeleine Duran, Sarah Saxton, Jon J Ladd, Malte Spielmann, Carlos Lois, Paul D. Lampe, Jay Shendure, Kelly R. Stevens, Cole Trapnell

Science. Author manuscript; available in PMC 2022 May 19.

Published in final edited form as: Science. 2021 Jul 2; 373(6550): 111–117. doi: 10.1126/science.abb9536

PMCID:: PMC9118175

Abstract Article PDF–1.1M

Select item 868921418.

The G4 resolvase RHAU regulates ventricular trabeculation and compaction through transcriptional and post-transcriptional mechanisms

Xinyi Huang, Ke Zhao, Mingyang Jiang, Dehui Qiu, Jun Zhou, Zhongzhou Yang

J Biol Chem. 2022 Jan; 298(1): 101449. Published online 2021 Nov 25. doi: 10.1016/j.jbc.2021.101449

PMCID:: PMC8689214

Abstract Article PDF–5.4M

Select item 858093819.

Generation and characterization of a Myh6-driven Cre knockin mouse line

Xinyan Huang, Lei Yan, Shan Kou, Jufeng Meng, Zhengkai Lu, Chao-Po Lin, Chen Liu, Hui Zhang

Transgenic Res. 2021; 30(6): 821–835. Published online 2021 Sep 20. doi: 10.1007/s11248-021-00285-4

PMCID:: PMC8580938

Abstract Article PDF–21M

Select item 845329220.

Fropofol prevents disease progression in mice with hypertrophic cardiomyopathy

Yiyuan Huang, Haisong Lu, Xianfeng Ren, Fazhao Li, Weiming Bu, Wenjie Liu, William P Dailey, Harumi Saeki, Kathleen Gabrielson, Roselle Abraham, Roderic Eckenhoff, Wei Dong Gao

Cardiovasc Res. 2020 May 1; 116(6): 1175–1185. Published online 2019 Aug 19. doi: 10.1093/cvr/cvz218

PMCID:: PMC8453292

Abstract Article PDF–1.0M

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