PMC Links for GEO Profiles (Select 37004265) - PMC

Pan Ma, Jing Liu, Juan Qin, Lulu Lai, Gyu Seong Heo, Hannah Luehmann, Deborah Sultan, Andrea Bredemeyer, Geetika Bajapa, Guoshuai Feng, Jesus Jimenez, Ruijun He, Antanisha Parks, Junedh Amrute, Ana Villanueva, Yongjian Liu, Chieh-Yu Lin, Matthias Mack, Kaushik Amancherla, Javid Moslehi, Kory J. Lavine

Circulation. Author manuscript; available in PMC 2024 Aug 14.

Published in final edited form as: Circulation. 2024 Jan 2; 149(1): 48–66. Published online 2023 Sep 25. doi: 10.1161/CIRCULATIONAHA.122.062551

PMCID:: PMC11323830

Abstract Article PDF–4.7M

Select item 112987884.

CTLA-4 expressing ILC3s restrain interleukin-23 mediated inflammation

Anees Ahmed, Ann M Joseph, Jordan Zhou, Veronika Horn, Jazib Uddin, Mengze Lyu, Jeremy Goc, JRI Live Cell Bank, Robbyn E. Sockolow, James B. Wing, Eric Vivier, Shimon Sakaguchi, Gregory F. Sonnenberg

Nature. Author manuscript; available in PMC 2024 Dec 12.

Published in final edited form as: Nature. 2024 Jun; 630(8018): 976–983. Published online 2024 Jun 12. doi: 10.1038/s41586-024-07537-3

PMCID:: PMC11298788

Abstract Article PDF–6.7M

Select item 110309395.

Regulation of arginase I activity and expression by both PD-1 and CTLA-4 on the myeloid-derived suppressor cells

Yu Liu, Yinyan Yu, Suguang Yang, Bin Zeng, Zhuohan Zhang, Guohui Jiao, Yuan Zhang, Limin Cai, Rongcun Yang

Cancer Immunol Immunother. 2009 May; 58(5): 687–697. Published online 2008 Oct 1. doi: 10.1007/s00262-008-0591-5

PMCID:: PMC11030939

Abstract Article PDF–581K

Select item 109400866.

PD-1 or CTLA-4 blockade promotes CD86-driven Treg responses upon radiotherapy of lymphocyte-depleted cancer in mice

Elselien Frijlink, Douwe M.T. Bosma, Julia Busselaar, Thomas W. Battaglia, Mo D. Staal, Inge Verbrugge, Jannie Borst

J Clin Invest. 2024 Mar 15; 134(6): e171154. Published online 2024 Feb 13. doi: 10.1172/JCI171154

PMCID:: PMC10940086

Abstract Article PDF–8.0M

Select item 108669337.

Innate and adaptive immune cell interaction drives inflammasome activation and hepatocyte apoptosis in murine liver injury from immune checkpoint inhibitors

Layla Shojaie, Jacob M. Bogdanov, Helia Alavifard, Mahmoud G. Mohamed, Aria Baktash, Myra Ali, Simeon Mahov, Sue Murray, Gary C. Kanel, Zhang-Xu Liu, Fumito Ito, Gino K. In, Akil Merchant, William Stohl, Lily Dara

Cell Death Dis. 2024 Feb; 15(2): 140. Published online 2024 Feb 14. doi: 10.1038/s41419-024-06535-7

PMCID:: PMC10866933

Abstract Article PDF–10M

Select item 106997728.

DECTIN-1: A modifier protein in CTLA-4 haploinsufficiency

Cynthia Turnbull, Josiah Bones, Maurice Stanley, Arti Medhavy, Hao Wang, Ayla May D. Lorenzo, Jean Cappello, Somasundhari Shanmuganandam, Abhimanu Pandey, Sandali Seneviratne, Grant J Brown, Xiangpeng Meng, David Fulcher, Gaetan Burgio, Si Ming Man, Carmen de Lucas Collantes, Mercedes Gasior, Eduardo López Granados, Pilar Martin, Simon H. Jiang, Matthew C. Cook, Julia I. Ellyard, Vicki Athanasopoulos, Ben Corry, Pablo F. Canete, Carola G. Vinuesa

Sci Adv. 2023 Dec 8; 9(49): eadi9566. Published online 2023 Dec 6. doi: 10.1126/sciadv.adi9566

PMCID:: PMC10699772

Abstract Article PDF–1.8M

Select item 106945969.

Genetic and pharmaceutical targeting of HIF1α allows combo-immunotherapy to boost graft vs. leukemia without exacerbation graft vs. host disease

Christopher Bailey, Yuanyi Wei, Jinsong Yan, Dan Huang, Peng Zhang, Chong Qi, Christopher Lazarski, JuanJuan Su, Fei Tang, Chun-shu Wong, Pan Zheng, Yan Liu, Yang Liu, Yin Wang

Cell Rep Med. 2023 Nov 21; 4(11): 101236. Published online 2023 Oct 11. doi: 10.1016/j.xcrm.2023.101236

PMCID:: PMC10694596

Abstract Article PDF–8.5M

Select item 1068708510.

The OX40-TRAF6 axis promotes CTLA-4 degradation to augment antitumor CD8⁺ T-cell immunity

Jizhang Yu, Jikai Cui, Xi Zhang, Heng Xu, Zhang Chen, Yuan Li, Yuqing Niu, Song Wang, Shuan Ran, Yanqiang Zou, Weicong Ye, Dan Zhang, Cheng Zhou, Jiahong Xia, Jie Wu

Cell Mol Immunol. 2023 Dec; 20(12): 1445–1456. Published online 2023 Nov 7. doi: 10.1038/s41423-023-01093-y

PMCID:: PMC10687085

Abstract Article PDF–4.8M

Select item 1066592111.

IFNγ and CTLA-4 Drive Hepatic CD4 T-Cell Tolerance and Protection From Autoimmunity in Mice

Daria Krzikalla, Alena Laschtowitz, Lisa Leypoldt, Cornelia Gottwick, Pia Averhoff, Sören Weidemann, Ansgar W. Lohse, Samuel Huber, Christoph Schramm, Dorothee Schwinge, Johannes Herkel, Antonella Carambia

Cell Mol Gastroenterol Hepatol. 2024; 17(1): 79–91. Published online 2023 Sep 19. doi: 10.1016/j.jcmgh.2023.09.006

PMCID:: PMC10665921

Abstract Article PDF–3.4M

Select item 1057814112.

Molecular, metabolic, and functional CD4 T cell paralysis in the lymph node impedes tumor control

Mengdi Guo, Diala Abd-Rabbo, Bruna C. Bertol, Madeleine Carew, Sabelo Lukhele, Laura M. Snell, Wenxi Xu, Giselle M. Boukhaled, Heidi Elsaesser, Marie Jo Halaby, Naoto Hirano, Tracy L. McGaha, David G. Brooks

Cell Rep. Author manuscript; available in PMC 2023 Oct 16.

Published in final edited form as: Cell Rep. 2023 Sep 26; 42(9): 113047. Published online 2023 Aug 30. doi: 10.1016/j.celrep.2023.113047

PMCID:: PMC10578141

Abstract Article PDF–3.5M

Select item 1018848413.

CTLA-4 suppresses hapten-induced contact hypersensitivity in atopic dermatitis model mice

Hiroe Tetsu, Kanako Nakayama, Taku Nishijo, Takuo Yuki, Masaaki Miyazawa

Sci Rep. 2023; 13: 7936. Published online 2023 May 16. doi: 10.1038/s41598-023-35139-y

Correction in:: Sci Rep. 2023; 13: 10552.

PMCID:: PMC10188484

Abstract Article PDF–3.0M

Select item 993017414.

T cells specific for α-myosin drive immunotherapy related myocarditis

Margaret L. Axelrod, Wouter C. Meijers, Elles M. Screever, Juan Qin, Mary Grace Carroll, Xiaopeng Sun, Elie Tannous, Yueli Zhang, Ayaka Sugiura, Brandie C. Taylor, Ann Hanna, Shaoyi Zhang, Kaushik Amancherla, Warren Tai, Jordan J. Wright, Spencer C. Wei, Susan R. Opalenik, Abigail L. Toren, Jeffrey C. Rathmell, P. Brent Ferrell, Elizabeth J. Phillips, Simon Mallal, Douglas B. Johnson, James P. Allison, Javid J. Moslehi, Justin M. Balko

Nature. Author manuscript; available in PMC 2023 Nov 16.

Published in final edited form as: Nature. 2022 Nov; 611(7937): 818–826. Published online 2022 Nov 16. doi: 10.1038/s41586-022-05432-3

PMCID:: PMC9930174

Abstract Article PDF–2.9M

Select item 986032115.

CTLA-4 on thymic epithelial cells complements Aire for T cell central tolerance

Daniel A. Michelson, Christophe Benoist, Diane Mathis

Proc Natl Acad Sci U S A. 2022 Nov 29; 119(48): e2215474119. Published online 2022 Nov 21. doi: 10.1073/pnas.2215474119

PMCID:: PMC9860321

Abstract Article PDF–2.9M

Select item 980913016.

Hormonal Therapies Upregulate MANF and Overcome Female Susceptibility to Immune Checkpoint Inhibitor-Myocarditis

Yaohua Zhang, Chengcao Sun, Yajuan Li, Juan Qin, Kaushik Amancherla, Ying Jing, Qingsong Hu, Ke Liang, Zhao Zhang, Youqiong Ye, Lisa A. Huang, Tina K. Nguyen, Sergey D. Egranov, Zilong Zhao, Andrew Wu, Yutao Xi, Jun Yao, Mien-Chie Hung, George A. Calin, Jie Cheng, Bora Lim, Lorenz H. Lehmann, Joe-Elie Salem, Douglas B. Johnson, Michael A. Curran, Dihua Yu, Leng Han, Radbod Darabi, Liuqing Yang, Javid J. Moslehi, Chunru Lin

Sci Transl Med. Author manuscript; available in PMC 2023 Jan 3.

Published in final edited form as: Sci Transl Med. 2022 Nov 2; 14(669): eabo1981. Published online 2022 Nov 2. doi: 10.1126/scitranslmed.abo1981

PMCID:: PMC9809130

Abstract Article PDF–4.8M

Select item 937835817.

A Mouse Model of the “LEAP” Study Reveals a Role for CTLA-4 in Preventing Peanut Allergy Induced by Environmental Peanut Exposure

James W. Krempski, Jyoti K. Lama, Koji Iijima, Takao Kobayashi, Mayumi Matsunaga, Hirohito Kita

J Allergy Clin Immunol. Author manuscript; available in PMC 2023 Aug 1.

Published in final edited form as: J Allergy Clin Immunol. 2022 Aug; 150(2): 425–439.e3. Published online 2022 Mar 12. doi: 10.1016/j.jaci.2022.02.024

PMCID:: PMC9378358

Abstract Article PDF–2.1M

Select item 866415818.

Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop

Francesco Marangoni, Ademi Zhakyp, Michela Corsini, Shannon N. Geels, Esteban Carrizosa, Martin Thelen, Vinidhra Mani, Jasper N. Prüßmann, Ross D. Warner, Aleksandra J. Ozga, Mauro Di Pilato, Shivashankar Othy, Thorsten R. Mempel

Cell. Author manuscript; available in PMC 2022 Jul 22.

Published in final edited form as: Cell. 2021 Jul 22; 184(15): 3998–4015.e19. Published online 2021 Jun 21. doi: 10.1016/j.cell.2021.05.027

PMCID:: PMC8664158

Abstract Article PDF–2.6M

Select item 840623019.

Absence of CD28-CTLA4-PD-L1 Costimulatory Molecules Reduces Herpes Simplex Virus 1 Reactivation

Harry H. Matundan, Ujjaldeep Jaggi, Jack Yu, Omid Akbari, Homayon Ghiasi

mBio. 2021 Jul-Aug; 12(4): e01176-21. Published online 2021 Jul 20. doi: 10.1128/mBio.01176-21

PMCID:: PMC8406230

Abstract Article PDF–3.5M

Select item 839095020.

A local regulatory T cell feedback circuit maintains immune homeostasis by pruning self-activated T cells

Harikesh S. Wong, Kyemyung Park, Anita Gola, Antonio P. Baptista, Christine H. Miller, Deeksha Deep, Meng Lou, Lisa F. Boyd, Alexander Y. Rudensky, Peter A. Savage, Grégoire Altan-Bonnet, John S. Tsang, Ronald N. Germain

Cell. Author manuscript; available in PMC 2022 Jul 22.

Published in final edited form as: Cell. 2021 Jul 22; 184(15): 3981–3997.e22. Published online 2021 Jun 21. doi: 10.1016/j.cell.2021.05.028

PMCID:: PMC8390950

Abstract Article PDF–5.0M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from GEO Profiles

Items: 1 to 20 of 166

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity