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Select item 110670141.

Class IIa HDAC4 and HDAC7 cooperatively regulate gene transcription in Th17 cell differentiation

Ka Lung Cheung, Li Zhao, Rajal Sharma, Anurupa Abhijit Ghosh, Michael Appiah, Yifei Sun, Anbalagan Jaganathan, Yuan Hu, Alannah LeJeune, Feihong Xu, Xinye Han, Xueting Wang, Fan Zhang, Chunyan Ren, Martin J. Walsh, Huabao Xiong, Alexander Tsankov, Ming-Ming Zhou

Proc Natl Acad Sci U S A. 2024 Apr 30; 121(18): e2312111121. Published online 2024 Apr 24. doi: 10.1073/pnas.2312111121

PMCID:: PMC11067014

Abstract Article PDF–1.9M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108424633.

SIKs regulate HDAC7 stabilization and cytokine recall in late-stage T cell effector differentiation

Rachel S. Helms, Alberto Marin-Gonzalez, Chirag H. Patel, Im-Hong Sun, Jiayu Wen, Robert D. Leone, Bridget Duvall, Run-Duo Gao, Taekjip Ha, Takashi Tsukamoto, Barbara S. Slusher, Joel L. Pomerantz, Jonathan D. Powell

J Immunol. Author manuscript; available in PMC 2024 Dec 15.

Published in final edited form as: J Immunol. 2023 Dec 15; 211(12): 1767–1782. doi: 10.4049/jimmunol.2300248

PMCID:: PMC10842463

Abstract Article PDF–3.1M

Select item 103859794.

Deacetylation of FOXP1 by HDAC7 potentiates self-renewal of mesenchymal stem cells

Shifeng Ling, Tienan Chen, Shaojiao Wang, Wei Zhang, Rujiang Zhou, Xuechun Xia, Zhengju Yao, Ying Fan, Song Ning, Jiayin Liu, Lianju Qin, Haley O. Tucker, Niansong Wang, Xizhi Guo

Stem Cell Res Ther. 2023; 14: 188. Published online 2023 Jul 28. doi: 10.1186/s13287-023-03376-7

PMCID:: PMC10385979

Abstract Article PDF–6.8M

Select item 93090935.

HDAC7 Activates IKK/NF-κB Signaling to Regulate Astrocyte-Mediated Inflammation

Jinwang Ye, Suyue Zhong, Yunsong Deng, Xuanbao Yao, Qiong Liu, Jian-Zhi Wang, Shifeng Xiao

Mol Neurobiol. 2022; 59(10): 6141–6157. Published online 2022 Jul 25. doi: 10.1007/s12035-022-02965-6

PMCID:: PMC9309093

Abstract Article PDF–11M

Select item 88536656.

A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair

Sergio Velasco-Aviles, Nikiben Patel, Angeles Casillas-Bajo, Laura Frutos-Rincón, Enrique Velasco, Juana Gallar, Peter Arthur-Farraj, Jose A Gomez-Sanchez, Hugo Cabedo

eLife. 2022; 11: e72917. Published online 2022 Jan 25. doi: 10.7554/eLife.72917

PMCID:: PMC8853665

Abstract Article PDF–42M

Select item 83132397.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 72599928.

Salt-inducible kinase 1 maintains HDAC7 stability to promote pathologic cardiac remodeling

Austin Hsu, Qiming Duan, Sarah McMahon, Yu Huang, Sarah A.B. Wood, Nathanael S. Gray, Biao Wang, Benoit G. Bruneau, Saptarsi M. Haldar

J Clin Invest. 2020 Jun 1; 130(6): 2966–2977. Published online 2020 May 4. doi: 10.1172/JCI133753

PMCID:: PMC7259992

Abstract Article PDF–8.8M

Select item 71872719.

A histone deacetylase 7‐derived peptide promotes vascular regeneration via facilitating 14‐3‐3γ phosphorylation

Junyao Yang, Ana Moraga, Jing Xu, Yue Zhao, Peiyi Luo, Ka Hou Lao, Andriana Margariti, Qiang Zhao, Wei Ding, Gang Wang, Min Zhang, Lei Zheng, Zhongyi Zhang, Yanhua Hu, Wen Wang, Lisong Shen, Alberto Smith, Ajay M Shah, Qian Wang, Lingfang Zeng

Stem Cells. 2020 Apr; 38(4): 556–573. Published online 2020 Jan 29. doi: 10.1002/stem.3122

PMCID:: PMC7187271

Abstract Article PDF–13M

Select item 713821810.

MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration

Qiong Feng, Yu Luo, Xiang-Nan Zhang, Xi-Fei Yang, Xiao-Yue Hong, Dong-Shen Sun, Xia-Chun Li, Yu Hu, Xiao-Guang Li, Jun-Fei Zhang, Xiao Li, Ying Yang, Qun Wang, Gong-Ping Liu, Jian-Zhi Wang

Autophagy. 2020; 16(4): 641–658. Published online 2019 Jun 28. doi: 10.1080/15548627.2019.1633862

PMCID:: PMC7138218

Abstract Article PDF–8.4M

Select item 659672011.

HDAC7 Ubiquitination by the E3 Ligase CBX4 Is Involved in Contextual Fear Conditioning Memory Formation

Xu Jing, Wen-Hai Sui, Shuai Wang, Xu-Feng Xu, Rong-rong Yuan, Xiao-Rong Chen, Hui-Xian Ma, Ying-Xiao Zhu, Jin-Kai Sun, Fan Yi, Zhe-Yu Chen, Yue Wang

J Neurosci. 2017 Apr 5; 37(14): 3848–3863. doi: 10.1523/JNEUROSCI.2773-16.2017

PMCID:: PMC6596720

Abstract Article PDF–3.5M

Select item 611389012.

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1

Gina E. Elsen, Francesco Bedogni, Rebecca D. Hodge, Theo K. Bammler, James W. MacDonald, Susan Lindtner, John L. R. Rubenstein, Robert F. Hevner

Front Neurosci. 2018; 12: 571. Published online 2018 Aug 22. doi: 10.3389/fnins.2018.00571

PMCID:: PMC6113890

Abstract Article PDF–4.8M

Select item 594303413.

Histone Deacetylase 7 mediates tissue-specific autoimmunity via control of innate effector function in invariant Natural Killer T Cells

Herbert G Kasler, Intelly S Lee, Hyung W Lim, Eric Verdin

eLife. 2018; 7: e32109. Published online 2018 Apr 17. doi: 10.7554/eLife.32109

PMCID:: PMC5943034

Abstract Article PDF–3.0M

Select item 558713714.

Tonic LAT-HDAC7 signals sustain Nur77 and Irf4 expression to tune naïve CD4 T cells

Darienne R. Myers, Tannia Lau, Evan Markegard, Hyung W. Lim, Herbert Kasler, Minghua Zhu, Andrea Barczak, John P. Huizar, Julie Zikherman, David J. Erle, Weiguo Zhang, Eric Verdin, Jeroen P. Roose

Cell Rep. Author manuscript; available in PMC 2017 Sep 6.

Published in final edited form as: Cell Rep. 2017 May 23; 19(8): 1558–1571. doi: 10.1016/j.celrep.2017.04.076

PMCID:: PMC5587137

Abstract Article PDF–979K

Select item 531311115.

Histone Deacetylase 1 Is Essential for Rod Photoreceptor Differentiation by Regulating Acetylation at Histone H3 Lysine 9 and Histone H4 Lysine 12 in the Mouse Retina

Renata C. Ferreira, Evgenya Y. Popova, Jessica James, Marcelo R. S. Briones, Samuel S. Zhang, Colin J. Barnstable

J Biol Chem. 2017 Feb 10; 292(6): 2422–2440. Published online 2016 Dec 27. doi: 10.1074/jbc.M116.756643

PMCID:: PMC5313111

Abstract Article PDF–6.2M

Select item 511001116.

In vivo conditional deletion of HDAC7 reveals its requirement to establish proper B lymphocyte identity and development

Alba Azagra, Lidia Román-González, Olga Collazo, Javier Rodríguez-Ubreva, Virginia G. de Yébenes, Bruna Barneda-Zahonero, Jairo Rodríguez, Manuel Castro de Moura, Joaquim Grego-Bessa, Irene Fernández-Duran, Abul B.M.M.K. Islam, Manel Esteller, Almudena R. Ramiro, Esteban Ballestar, Maribel Parra

J Exp Med. 2016 Nov 14; 213(12): 2591–2601. doi: 10.1084/jem.20150821