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Items: 1 to 20 of 110

1.
Telomeric DNA breaks in human induced pluripotent stem cells trigger ATR-mediated arrest and telomerase-independent telomere damage repair
Katrina N Estep, John W Tobias, Rafael J Fernandez, Brinley M Beveridge, F Brad Johnson
J Mol Cell Biol. 2024 Mar; 16(3): mjad058. Published online 2023 Sep 28. doi: 10.1093/jmcb/mjad058
PMCID:
PMC11429528
AbstractArticlePDF–2.6M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Chromatin Remodeling Enzyme Snf2h Is Essential for Retinal Cell Proliferation and Photoreceptor Maintenance
Andrea Kuzelova, Naoko Dupacova, Barbora Antosova, Sweetu Susan Sunny, Zbynek Kozmik, Jr., Jan Paces, Arthur I. Skoultchi, Tomas Stopka, Zbynek Kozmik
Cells. 2023 Apr; 12(7): 1035. Published online 2023 Mar 28. doi: 10.3390/cells12071035
PMCID:
PMC10093269
AbstractArticlePDF–21M
4.
Intrinsic neural stem cell properties define brain hypersensitivity to genotoxic stress
Argyro Kalogeropoulou, Maria Mougkogianni, Marianna Iliadou, Eleni Nikolopoulou, Stefanos Flordelis, Alexandra Kanellou, Marina Arbi, Sofia Nikou, Jadwiga Nieminuszczy, Wojciech Niedzwiedz, Dimitrios Kardamakis, Vasiliki Bravou, Zoi Lygerou, Stavros Taraviras
Stem Cell Reports. 2022 Jun 14; 17(6): 1395–1410. Published online 2022 May 26. doi: 10.1016/j.stemcr.2022.04.018
PMCID:
PMC9214316
AbstractArticlePDF–4.9M
5.
Ataxia-televangelist mutated (ATM)/ ATR serine/threonine kinase (ATR)-mediated RAD51 recombinase (RAD51) promotes osteogenic differentiation and inhibits osteoclastogenesis in osteoporosis
Minli Qiu, Liudan Tu, Minjing Zhao, Mingcan Yang, Jun Qi, Ya Xie, Jieruo Gu
Bioengineered. 2022; 13(2): 4201–4211. Published online 2022 Feb 17. doi: 10.1080/21655979.2022.2026729
PMCID:
PMC8974111
AbstractArticlePDF–2.6M
6.
Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells
Evan R. Abt, Thuc M. Le, Amanda M. Dann, Joseph R. Capri, Soumya Poddar, Vincent Lok, Luyi Li, Keke Liang, Amanda L. Creech, Khalid Rashid, Woosuk Kim, Nanping Wu, Jing Cui, Arthur Cho, Hailey Rose Lee, Ethan W. Rosser, Jason M. Link, Johannes Czernin, Ting-Ting Wu, Robert Damoiseaux, David W. Dawson, Timothy R. Donahue, Caius G. Radu
Cell Rep. Author manuscript; available in PMC 2022 Mar 3.
Published in final edited form as: Cell Rep. 2022 Jan 11; 38(2): 110236. doi: 10.1016/j.celrep.2021.110236
PMCID:
PMC8893345
AbstractArticlePDF–2.8M
7.
Differential roles of ATR and ATM in p53, Chk1, and histone H2AX phosphorylation in response to hyperoxia: ATR-dependent ATM activation
Amit Kulkarni, Kumuda C. Das
Am J Physiol Lung Cell Mol Physiol. Author manuscript; available in PMC 2022 Jan 24.
Published in final edited form as: Am J Physiol Lung Cell Mol Physiol. 2008 May; 294(5): L998–L1006. Published online 2008 Mar 14. doi: 10.1152/ajplung.00004.2008
PMCID:
PMC8786037
AbstractArticlePDF–1.8M
8.
Cell-fate transition and determination analysis of mouse male germ cells throughout development
Jiexiang Zhao, Ping Lu, Cong Wan, Yaping Huang, Manman Cui, Xinyan Yang, Yuqiong Hu, Yi Zheng, Ji Dong, Mei Wang, Shu Zhang, Zhaoting Liu, Shuhui Bian, Xiaoman Wang, Rui Wang, Shaofang Ren, Dazhuang Wang, Zhaokai Yao, Gang Chang, Fuchou Tang, Xiao-Yang Zhao
Nat Commun. 2021; 12: 6839. Published online 2021 Nov 25. doi: 10.1038/s41467-021-27172-0
PMCID:
PMC8617176
AbstractArticlePDF–14M
9.
Alternative Functions of Cell Cycle-Related and DNA Repair Proteins in Post-mitotic Neurons
Remi Akagawa, Yo-ichi Nabeshima, Takeshi Kawauchi
Front Cell Dev Biol. 2021; 9: 753175. Published online 2021 Oct 20. doi: 10.3389/fcell.2021.753175
PMCID:
PMC8564117
AbstractArticlePDF–2.2M
10.
ATR regulates neuronal activity by modulating presynaptic firing
Murat Kirtay, Josefine Sell, Christian Marx, Holger Haselmann, Mihai Ceanga, Zhong-Wei Zhou, Vahid Rahmati, Joanna Kirkpatrick, Katrin Buder, Paulius Grigaravicius, Alessandro Ori, Christian Geis, Zhao-Qi Wang
Nat Commun. 2021; 12: 4067. Published online 2021 Jul 1. doi: 10.1038/s41467-021-24217-2
PMCID:
PMC8249387
AbstractArticlePDF–11M
11.
The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation
Feng Li, Tsz Y. Lo, Leann Miles, Qin Wang, Harun N. Noristani, Dan Li, Jingwen Niu, Shannon Trombley, Jessica I. Goldshteyn, Chuxi Wang, Shuchao Wang, Jingyun Qiu, Katarzyna Pogoda, Kalpana Mandal, Megan Brewster, Panteleimon Rompolas, Ye He, Paul A. Janmey, Gareth M. Thomas, Shuxin Li, Yuanquan Song
Nat Commun. 2021; 12: 3845. Published online 2021 Jun 22. doi: 10.1038/s41467-021-24131-7
PMCID:
PMC8219705
AbstractArticlePDF–13M
12.
Post-transcriptional regulation by the exosome complex is required for cell survival and forebrain development via repression of P53 signaling
Pauline Antonie Ulmke, Yuanbin Xie, Godwin Sokpor, Linh Pham, Orr Shomroni, Tea Berulava, Joachim Rosenbusch, Uttiya Basu, Andre Fischer, Huu Phuc Nguyen, Jochen F. Staiger, Tran Tuoc
Development. 2021 Feb 1; 148(3): dev188276. Published online 2021 Feb 8. doi: 10.1242/dev.188276
PMCID:
PMC7888709
AbstractArticle
13.
Progenitor death drives retinal dysplasia and neuronal degeneration in a mouse model of ATRIP-Seckel syndrome
Gabriel E. Matos-Rodrigues, Pedro B. Tan, Maurício Rocha-Martins, Clara F. Charlier, Anielle L. Gomes, Felipe Cabral-Miranda, Paulius Grigaravicius, Thomas G. Hofmann, Pierre-Olivier Frappart, Rodrigo A. P. Martins
Dis Model Mech. 2020 Oct 1; 13(10): dmm045807. Published online 2020 Oct 30. doi: 10.1242/dmm.045807
PMCID:
PMC7648607
AbstractArticle
14.
ATRIP protects progenitor cells against DNA damage in vivo
Gabriel E. Matos-Rodrigues, Paulius Grigaravicius, Bernard S. Lopez, Thomas Hofmann, Pierre-Olivier Frappart, Rodrigo A. P. Martins
Cell Death Dis. 2020 Oct; 11(10): 923. Published online 2020 Oct 28. doi: 10.1038/s41419-020-03090-9
Correction in:
Cell Death Dis. 2020 Dec; 11(12): 1074.
PMCID:
PMC7591577
AbstractArticlePDF–3.4M
15.
ATR is essential for preservation of cell mechanics and nuclear integrity during interstitial migration
Gururaj Rao Kidiyoor, Qingsen Li, Giulia Bastianello, Christopher Bruhn, Irene Giovannetti, Adhil Mohamood, Galina V. Beznoussenko, Alexandre Mironov, Matthew Raab, Matthieu Piel, Umberto Restuccia, Vittoria Matafora, Angela Bachi, Sara Barozzi, Dario Parazzoli, Emanuela Frittoli, Andrea Palamidessi, Tito Panciera, Stefano Piccolo, Giorgio Scita, Paolo Maiuri, Kristina M. Havas, Zhong-Wei Zhou, Amit Kumar, Jiri Bartek, Zhao-Qi Wang, Marco Foiani
Nat Commun. 2020; 11: 4828. Published online 2020 Sep 24. doi: 10.1038/s41467-020-18580-9
PMCID:
PMC7518249
AbstractArticlePDF–4.3M
16.
A Survey of Essential Genome Stability Genes Reveals That Replication Stress Mitigation Is Critical for Peri-Implantation Embryogenesis
Georgia R. Kafer, Anthony J. Cesare
Front Cell Dev Biol. 2020; 8: 416. Published online 2020 May 29. doi: 10.3389/fcell.2020.00416
PMCID:
PMC7274024
AbstractArticlePDF–1.3M
17.
GCNA Interacts with Spartan and Topoisomerase II to Regulate Genome Stability
Gregoriy A. Dokshin, Gregory M. Davis, Ashley D. Sawle, Matthew D. Eldridge, Peter K. Nicholls, Taylin E. Gourley, Katherine A. Romer, Luke W. Molesworth, Hannah R. Tatnell, Ahmet R. Ozturk, Dirk G. de Rooij, Gregory J. Hannon, David C. Page, Craig C. Mello, Michelle A. Carmell
Dev Cell. Author manuscript; available in PMC 2021 Jan 6.
Published in final edited form as: Dev Cell. 2020 Jan 6; 52(1): 53–68.e6. Published online 2019 Dec 12. doi: 10.1016/j.devcel.2019.11.006
PMCID:
PMC7227305
AbstractArticlePDF–1.3M
18.
Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss
Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs
Cells. 2020 Apr; 9(4): 931. Published online 2020 Apr 10. doi: 10.3390/cells9040931
PMCID:
PMC7227028
AbstractArticlePDF–5.4M
19.
Proximal tubule ATR regulates DNA repair to prevent maladaptive renal injury responses
Seiji Kishi, Craig R. Brooks, Kensei Taguchi, Takaharu Ichimura, Yutaro Mori, Akinwande Akinfolarin, Navin Gupta, Pierre Galichon, Bertha C. Elias, Tomohisa Suzuki, Qian Wang, Leslie Gewin, Ryuji Morizane, Joseph V. Bonventre
J Clin Invest. 2019 Nov 1; 129(11): 4797–4816. Published online 2019 Oct 7. doi: 10.1172/JCI122313
PMCID:
PMC6819104
AbstractArticlePDF–41M
20.
New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules
Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer
J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252
PMCID:
PMC6602300
AbstractArticle

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