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Select item 108101451.

Idax and Rinf facilitate expression of Tet enzymes to promote neural and suppress trophectodermal programs during differentiation of embryonic stem cells

Antoine Abou-Jaoude, Cheng-Yen Huang, Julio C. Flores, Mirunalini Ravichandran, Run Lei, Stephanie Chrysanthou, Meelad M. Dawlaty

Stem Cell Res. Author manuscript; available in PMC 2024 Jan 25.

Published in final edited form as: Stem Cell Res. 2022 May; 61: 102770. Published online 2022 Mar 29. doi: 10.1016/j.scr.2022.102770

PMCID:: PMC10810145

Abstract Article PDF–1.8M

Select item 107631202.

CXXC5 mitigates P. gingivalis-inhibited cementogenesis by influencing mitochondrial biogenesis

Li Ma, Huiyi Wang, Xin Huang, Hantao Huang, Yan Peng, Heyu Liu, Xiaoxuan Wang, Zhengguo Cao

Cell Commun Signal. 2024; 22: 4. Published online 2024 Jan 2. doi: 10.1186/s12964-023-01283-1

PMCID:: PMC10763120

Abstract Article PDF–6.8M

Select item 105427493.

Tle4 controls both developmental acquisition and early post-natal maturation of corticothalamic projection neuron identity

Maria J. Galazo, David A. Sweetser, Jeffrey D. Macklis

Cell Rep. Author manuscript; available in PMC 2023 Oct 1.

Published in final edited form as: Cell Rep. 2023 Aug 29; 42(8): 112957. Published online 2023 Aug 9. doi: 10.1016/j.celrep.2023.112957

PMCID:: PMC10542749

Abstract Article PDF–3.6M

Select item 104741144.

Inhibiting the cytosolic function of CXXC5 accelerates diabetic wound healing by enhancing angiogenesis and skin repair

Eunhwan Kim, Seol Hwa Seo, Yumi Hwang, Yeong Chan Ryu, Heejene Kim, Kyoung-Mi Lee, Jin Woo Lee, Kwang Hwan Park, Kang-Yell Choi

Exp Mol Med. 2023 Aug; 55(8): 1770–1782. Published online 2023 Aug 1. doi: 10.1038/s12276-023-01064-3

PMCID:: PMC10474114

Abstract Article PDF–7.3M

Select item 99546855.

CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD₂

Yeong Chan Ryu, Jiyeon Park, You-Rin Kim, Sehee Choi, Geon-Uk Kim, Eunhwan Kim, Yumi Hwang, Heejene Kim, Gyoonhee Han, Soung-Hoon Lee, Kang-Yell Choi

Cells. 2023 Feb; 12(4): 555. Published online 2023 Feb 9. doi: 10.3390/cells12040555

PMCID:: PMC9954685

Abstract Article PDF–4.0M

Select item 95348556.

Metabolic improvement and liver regeneration by inhibiting CXXC5 function for non-alcoholic steatohepatitis treatment

Seol Hwa Seo, Eunhwan Kim, Minguen Yoon, Soung-Hoon Lee, Byung-Hyun Park, Kang-Yell Choi

Exp Mol Med. 2022 Sep; 54(9): 1511–1523. Published online 2022 Sep 16. doi: 10.1038/s12276-022-00851-8

PMCID:: PMC9534855

Abstract Article PDF–8.8M

Select item 89825077.

Inhibition of CXXC5 function reverses obesity‐related metabolic diseases

Seol Hwa Seo, Eunhwan Kim, Soung‐Hoon Lee, Yong‐ho Lee, Dai Hoon Han, Hyesun Go, Je Kyung Seong, Kang‐Yell Choi

Clin Transl Med. 2022 Apr; 12(4): e742. Published online 2022 Apr 5. doi: 10.1002/ctm2.742

PMCID:: PMC8982507

Abstract Article PDF–7.7M

Select item 71607258.

CXXC5 Attenuates Pulmonary Fibrosis in a Bleomycin-Induced Mouse Model and MLFs by Suppression of the CD40/CD40L Pathway

Wei Cheng, Fangfang Wang, Airan Feng, Xiaodan Li, Wencheng Yu

Biomed Res Int. 2020; 2020: 7840652. Published online 2020 Apr 4. doi: 10.1155/2020/7840652

PMCID:: PMC7160725

Abstract Article PDF–3.0M

Select item 67165229.

Rinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells

Mirunalini Ravichandran, Run Lei, Qin Tang, Yilin Zhao, Joun Lee, Liyang Ma, Stephanie Chrysanthou, Benjamin M. Lorton, Ales Cvekl, David Shechter, Deyou Zheng, Meelad M. Dawlaty

Cell Rep. Author manuscript; available in PMC 2019 Aug 30.

Published in final edited form as: Cell Rep. 2019 Aug 20; 28(8): 1993–2003.e5. doi: 10.1016/j.celrep.2019.07.080

PMCID:: PMC6716522

Abstract Article PDF–2.0M

Select item 645885010.

CXXC5 mediates growth plate senescence and is a target for enhancement of longitudinal bone growth

Sehee Choi, Hyun-Yi Kim, Pu-Hyeon Cha, Seol Hwa Seo, Chulho Lee, Yejoo Choi, Wookjin Shin, Yunseok Heo, Gyoonhee Han, Weontae Lee, Kang-Yell Choi

Life Sci Alliance. 2019 Apr; 2(2): e201800254. Published online 2019 Apr 10. doi: 10.26508/lsa.201800254

PMCID:: PMC6458850

Abstract Article PDF–2.9M

Select item 623163811.

Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each

Afzal M. Dogar, Ramona Pauchard-Batschulat, Barbara Grisoni-Neupert, Larry Richman, Alexandra Paillusson, Sylvain Pradervand, Otto Hagenbüchle, Giovanna Ambrosini, Christoph D. Schmid, Philipp Bucher, Lukas C. Kühn

PLoS One. 2018; 13(11): e0206823. Published online 2018 Nov 12. doi: 10.1371/journal.pone.0206823

PMCID:: PMC6231638

Abstract Article PDF–3.8M

Select item 541333212.

Epigenetic regulator CXXC5 recruits DNA demethylase Tet2 to regulate TLR7/9-elicited IFN response in pDCs

Shixin Ma, Xiaoling Wan, Zihou Deng, Lei Shi, Congfang Hao, Zhenyuan Zhou, Chun Zhou, Yiyuan Fang, Jinghua Liu, Jing Yang, Xia Chen, Tiantian Li, Aiping Zang, Shigang Yin, Bin Li, Joel Plumas, Laurence Chaperot, Xiaoming Zhang, Guoliang Xu, Lubin Jiang, Nan Shen, Sidong Xiong, Xiaoming Gao, Yan Zhang, Hui Xiao

J Exp Med. 2017 May 1; 214(5): 1471–1491. doi: 10.1084/jem.20161149

PMCID:: PMC5413332

Abstract Article PDF–3.0M

Select item 509445313.

Corticothalamic projection neuron development beyond subtype specification: Fog2 and intersectional controls regulate intra-class neuronal diversity

Maria J. Galazo, Jason G. Emsley, Jeffrey D. Macklis

Neuron. Author manuscript; available in PMC 2017 Jul 6.

Published in final edited form as: Neuron. 2016 Jul 6; 91(1): 90–106. Published online 2016 Jun 16. doi: 10.1016/j.neuron.2016.05.024

PMCID:: PMC5094453

Abstract Article PDF–1.6M

Select item 501393714.

Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms

Angela Stoddart, Zhijian Qian, Anthony A. Fernald, Rachel J. Bergerson, Jianghong Wang, Theodore Karrison, John Anastasi, Elizabeth T. Bartom, Aaron L. Sarver, Megan E. McNerney, David A. Largaespada, Michelle M. Le Beau

Haematologica. 2016 Jun; 101(6): e232–e236. doi: 10.3324/haematol.2015.139527

PMCID:: PMC5013937

Article PDF–980K

Select item 449341115.

The Dishevelled-binding protein CXXC5 negatively regulates cutaneous wound healing

Soung-Hoon Lee, Mi-Yeon Kim, Hyun-Yi Kim, Young-Mi Lee, Heesu Kim, Kyoung Ae Nam, Mi Ryung Roh, Do Sik Min, Kee Yang Chung, Kang-Yell Choi

J Exp Med. 2015 Jun 29; 212(7): 1061–1080. doi: 10.1084/jem.20141601

PMCID:: PMC4493411

Abstract Article PDF–6.7M

Select item 442318916.

CXXC5 is a negative-feedback regulator of the Wnt/β-catenin pathway involved in osteoblast differentiation

H-Y Kim, J-Y Yoon, J-H Yun, K-W Cho, S-H Lee, Y-M Rhee, H-S Jung, H J Lim, H Lee, J Choi, J-N Heo, W Lee, K T No, D Min, K-Y Choi

Cell Death Differ. 2015 Jun; 22(6): 912–920. Published online 2015 Jan 30. doi: 10.1038/cdd.2014.238

PMCID:: PMC4423189

Abstract Article PDF–3.3M

Select item 374619817.

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal

Alessia Gagliardi, Nicholas P Mullin, Zi Ying Tan, Douglas Colby, Anastasia I Kousa, Florian Halbritter, Jason T Weiss, Anastasia Felker, Karel Bezstarosti, Rebecca Favaro, Jeroen Demmers, Silvia K Nicolis, Simon R Tomlinson, Raymond A Poot, Ian Chambers

EMBO J. 2013 Aug 14; 32(16): 2231–2247. Published online 2013 Jul 26. doi: 10.1038/emboj.2013.161

PMCID:: PMC3746198

Abstract Article PDF–2.9M

Select item 357241018.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163