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Items: 1 to 20 of 38

1.
Mutations in linker-2 of KLF1 impair expression of membrane transporters and cytoskeletal proteins causing hemolysis
Stephen Huang, Casie Reed, Melissa Ilsley, Graham Magor, Michael Tallack, Michael Landsberg, Helen Mitchell, Kevin Gillinder, Andrew Perkins
Nat Commun. 2024; 15: 7019. Published online 2024 Aug 15. doi: 10.1038/s41467-024-50579-4
PMCID:
PMC11327367
AbstractArticlePDF–4.2M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
PRDM16 expression and function in mammalian cochlear development
Michael Ebeid, Kathy Barnas, Hongji Zhang, Amal Yaghmour, Gabriele Noreikaite, Bryan C. Bjork
Dev Dyn. 2022 Oct; 251(10): 1666–1683. Published online 2022 May 7. doi: 10.1002/dvdy.480
PMCID:
PMC9790675
AbstractArticlePDF–17M
4.
Regulator of Cell Cycle Protein (RGCC/RGC-32) Protects against Pulmonary Fibrosis
Irina G. Luzina, Violeta Rus, Virginia Lockatell, Jean-Paul Courneya, Brian S. Hampton, Rita Fishelevich, Alexander V. Misharin, Nevins W. Todd, Tudor C. Badea, Horea Rus, Sergei P. Atamas
Am J Respir Cell Mol Biol. 2022 Feb; 66(2): 146–157. Published online 2021 Oct 20. doi: 10.1165/rcmb.2021-0022OC
PMCID:
PMC8845131
AbstractArticlePDF–1.7M
5.
RGC-32 Acts as a Hub to Regulate the Transcriptomic Changes Associated With Astrocyte Development and Reactive Astrocytosis
Alexandru Tatomir, Austin Beltrand, Vinh Nguyen, Jean-Paul Courneya, Dallas Boodhoo, Cornelia Cudrici, Dafin F. Muresanu, Violeta Rus, Tudor C. Badea, Horea Rus
Front Immunol. 2021; 12: 705308. Published online 2021 Jul 29. doi: 10.3389/fimmu.2021.705308
PMCID:
PMC8358671
AbstractArticlePDF–15M
6.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
7.
RGC-32 Regulates Generation of Reactive Astrocytes in Experimental Autoimmune Encephalomyelitis
Alexandru Tatomir, Austin Beltrand, Vinh Nguyen, Dallas Boodhoo, Armugam Mekala, Cornelia Cudrici, Tudor C. Badea, Dafin F. Muresanu, Violeta Rus, Horea Rus
Front Immunol. 2020; 11: 608294. Published online 2021 Jan 25. doi: 10.3389/fimmu.2020.608294
PMCID:
PMC7868332
AbstractArticlePDF–8.1M
8.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
9.
An atlas of genetic influences on osteoporosis in humans and mice
John A. Morris, John P. Kemp, Scott E. Youlten, Laetitia Laurent, John G. Logan, Ryan C. Chai, Nicholas A. Vulpescu, Vincenzo Forgetta, Aaron Kleinman, Sindhu T. Mohanty, C. Marcelo Sergio, Julian Quinn, Loan Nguyen-Yamamoto, Aimee-Lee Luco, Jinchu Vijay, Marie-Michelle Simon, Albena Pramatarova, Carolina Medina-Gomez, Katerina Trajanoska, Elena J. Ghirardello, Natalie C. Butterfield, Katharine F. Curry, Victoria D. Leitch, Penny C. Sparkes, Anne-Tounsia Adoum, Naila S. Mannan, Davide S.K. Komla-Ebri, Andrea S. Pollard, Hannah F. Dewhurst, Thomas A.D. Hassall, Michael-John G. Beltejar, 23andMe Research Team, Douglas J. Adams, Suzanne M. Vaillancourt, Stephen Kaptoge, Paul Baldock, Cyrus Cooper, Jonathan Reeve, Evangelia E. Ntzani, Evangelos Evangelou, Claes Ohlsson, David Karasik, Fernando Rivadeneira, Douglas P. Kiel, Jonathan H. Tobias, Celia L. Gregson, Nicholas C. Harvey, Elin Grundberg, David Goltzman, David J. Adams, Christopher J. Lelliott, David A. Hinds, Cheryl L. Ackert-Bicknell, Yi-Hsiang Hsu, Matthew T. Maurano, Peter I. Croucher, Graham R. Williams, J. H. Duncan Bassett, David M. Evans, J. Brent Richards
Nat Genet. Author manuscript; available in PMC 2019 Jun 30.
Published in final edited form as: Nat Genet. 2019 Feb; 51(2): 258–266. Published online 2018 Dec 31. doi: 10.1038/s41588-018-0302-x
PMCID:
PMC6358485
AbstractArticlePDF–1.8M
10.
RGC-32 regulates reactive astrocytosis and extracellular matrix deposition in experimental autoimmune encephalomyelitis
Alexandru Tatomir, Cosmin A. Tegla, Alvaro Martin, Dallas Boodhoo, Vinh Nguyen, Adam J. Sugarman, Armugam Mekala, Freidrich Anselmo, Anamaria Talpos-Caia, Cornelia Cudrici, Tudor C. Badea, Violeta Rus, Horea Rus
Immunol Res. Author manuscript; available in PMC 2019 Aug 1.
Published in final edited form as: Immunol Res. 2018 Aug; 66(4): 445–461. doi: 10.1007/s12026-018-9011-x
PMCID:
PMC6330259
AbstractArticlePDF–4.7M
11.
Loss of Response Gene to Complement 32 (RGC-32) in Diabetic Mouse Retina Is Involved in Retinopathy Development
Wen-Ling Liao, Jane-Ming Lin, Shih-Ping Liu, Shih-Yin Chen, Hui-Ju Lin, Yeh-Han Wang, Yu-Jie Lei, Yu-Chuen Huang, Fuu-Jen Tsai
Int J Mol Sci. 2018 Nov; 19(11): 3629. Published online 2018 Nov 17. doi: 10.3390/ijms19113629
PMCID:
PMC6275084
AbstractArticlePDF–3.9M
12.
Response Gene to Complement 32 Maintains Blood Pressure Homeostasis by Regulating α-Adrenergic Receptor Expression
Jun-Ming Tang, Ning Shi, Kun Dong, Scott A. Brown, Amanda E. Coleman, Matthew A. Boegehold, Shi-You Chen
Circ Res. Author manuscript; available in PMC 2019 Oct 12.
Published in final edited form as: Circ Res. 2018 Oct 12; 123(9): 1080–1090. doi: 10.1161/CIRCRESAHA.118.313266
PMCID:
PMC6214659
AbstractArticlePDF–1.0M
13.
RGC-32 Promotes Th17 Cell Differentiation and Enhances Experimental Autoimmune Encephalomyelitis
Violeta Rus, Vinh Nguyen, Alexandru Tatomir, Jason R. Lees, Armugam P. Mekala, Dallas Boodhoo, Cosmin A. Tegla, Irina G. Luzina, Paul A. Antony, Cornelia D. Cudrici, Tudor C. Badea, Horea G. Rus
J Immunol. Author manuscript; available in PMC 2018 Oct 22.
Published in final edited form as: J Immunol. 2017 May 15; 198(10): 3869–3877. Published online 2017 Mar 29. doi: 10.4049/jimmunol.1602158
PMCID:
PMC6197070
AbstractArticlePDF–820K
14.
Response gene to complement 32 suppresses adipose tissue thermogenic genes through inhibiting β3-adrenergic receptor/mTORC1 signaling
Sisi Chen, Xiaohan Mei, Amelia Yin, Hang Yin, Xiao-Bing Cui, Shi-You Chen
FASEB J. 2018 Sep; 32(9): 4836–4847. Published online 2018 Mar 26. doi: 10.1096/fj.201701508R
PMCID:
PMC6103168
AbstractArticle
15.
Angiogenic factor imbalance precedes complement deposition in placentae of the BPH/5 model of preeclampsia
Jennifer L. Sones, Audrey A. Merriam, Angelina Seffens, Dex-Ann Brown-Grant, Scott D. Butler, Anna M. Zhao, Xinjing Xu, Carrie J. Shawber, Jennifer K. Grenier, Nataki C. Douglas
FASEB J. 2018 May; 32(5): 2574–2586. Published online 2018 Jan 8. doi: 10.1096/fj.201701008R
PMCID:
PMC5901389
AbstractArticle
16.
RGC32 promotes bleomycin-induced systemic sclerosis in a murine disease model by modulating classically activated macrophage function
Chenming Sun, Shi-You Chen
J Immunol. Author manuscript; available in PMC 2019 Apr 15.
Published in final edited form as: J Immunol. 2018 Apr 15; 200(8): 2777–2785. Published online 2018 Mar 5. doi: 10.4049/jimmunol.1701542
PMCID:
PMC5893351
AbstractArticlePDF–2.8M
17.
Renal proteomic analysis of RGC-32 knockout mice reveals the potential mechanism of RGC-32 in regulating cell cycle
Yu-Jie Hu, Qian Zhou, Zhu-Yin Li, Dan Feng, Lei Sun, Yun-Lin Shen, Wen-Yan Huang
Am J Transl Res. 2018; 10(3): 847–856. Published online 2018 Mar 15.
PMCID:
PMC5883125
AbstractArticlePDF–1.0M
18.
RGC-32 deficiency protects endothelial cell from inflammation and attenuates atherosclerosis
Xiao-Bing Cui, Jun-Na Luan, Kun Dong, Sisi Chen, Yongyi Wang, Wendy T. Watford, Shi-You Chen
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2019 Apr 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2018 Apr; 38(4): e36–e47. Published online 2018 Feb 15. doi: 10.1161/ATVBAHA.117.310656
PMCID:
PMC5864544
AbstractArticlePDF–1.0M
19.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
20.
RGC-32 is a novel regulator of the T-lymphocyte cell cycle
Cosmin A. Tegla, Cornelia D. Cudrici, Vinh Nguyen, Jacob Danoff, Adam M. Kruszewski, Dallas Boodhoo, Armugam P. Mekala, Sonia I. Vlaicu, Ching Chen, Violeta Rus, Tudor C. Badea, Horea Rus
Exp Mol Pathol. Author manuscript; available in PMC 2016 Oct 12.
Published in final edited form as: Exp Mol Pathol. 2015 Jun; 98(3): 328–337. Published online 2015 Mar 11. doi: 10.1016/j.yexmp.2015.03.011
PMCID:
PMC5061555
AbstractArticlePDF–1011K

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