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Items: 1 to 20 of 141

1.
Synthetical lethality of Werner helicase and mismatch repair deficiency is mediated by p53 and PUMA in colon cancer
Suisui Hao, Jingshan Tong, Anupma Jha, Denise Risnik, Darleny Lizardo, Xinyan Lu, Ajay Goel, Patricia L. Opresko, Jian Yu, Lin Zhang
Proc Natl Acad Sci U S A. 2022 Dec 20; 119(51): e2211775119. Published online 2022 Dec 12. doi: 10.1073/pnas.2211775119
PMCID:
PMC9907101
AbstractArticlePDF–5.9M
2.
Long non-coding RNA HOTAIRincreased mechanical stimulation-induced apoptosis by regulating microRNA-221/BBC3 axis in C28/I2 cells
Tiansheng Zheng, Jishang Huang, Jinliang Lai, Qingluo Zhou, Tong Liu, Qiang Xu, Guanglin Ji, Yongjun Ye
Bioengineered. 2021; 12(2): 10734–10744. Published online 2021 Dec 7. doi: 10.1080/21655979.2021.2003129
PMCID:
PMC8810135
AbstractArticlePDF–1.9M
3.
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context
Marcel Morgenstern, Christian D. Peikert, Philipp Lübbert, Ida Suppanz, Cinzia Klemm, Oliver Alka, Conny Steiert, Nataliia Naumenko, Alexander Schendzielorz, Laura Melchionda, Wignand W.D. Mühlhäuser, Bettina Knapp, Jakob D. Busch, Sebastian B. Stiller, Stefan Dannenmaier, Caroline Lindau, Mariya Licheva, Christopher Eickhorst, Riccardo Galbusera, Ralf M. Zerbes, Michael T. Ryan, Claudine Kraft, Vera Kozjak-Pavlovic, Friedel Drepper, Sven Dennerlein, Silke Oeljeklaus, Nikolaus Pfanner, Nils Wiedemann, Bettina Warscheid
Cell Metab. 2021 Dec 7; 33(12): 2464–2483.e18. doi: 10.1016/j.cmet.2021.11.001
PMCID:
PMC8664129
AbstractArticle
4.
Genome-wide mRNA profiling identifies X-box-binding protein 1 (XBP1) as an IRE1 and PUMA repressor
Magdalena Gebert, Aleksandra Sobolewska, Sylwia Bartoszewska, Aleksandra Cabaj, David K. Crossman, Jarosław Króliczewski, Piotr Madanecki, Michał Dąbrowski, James F. Collawn, Rafal Bartoszewski
Cell Mol Life Sci. 2021 Nov; 78(21-22): 7061–7080. Published online 2021 Oct 12. doi: 10.1007/s00018-021-03952-1
PMCID:
PMC8558229
AbstractArticlePDF–6.4M
5.
FBXL20 promotes breast cancer malignancy by inhibiting apoptosis through degradation of PUMA and BAX
Rajesh Kumar Manne, Yashika Agrawal, Sunil K. Malonia, Shahid Banday, Sarathkumar Edachery, Asha Patel, Avinash Kumar, Praveenkumar Shetty, Manas Kumar Santra
J Biol Chem. 2021 Oct; 297(4): 101253. Published online 2021 Sep 26. doi: 10.1016/j.jbc.2021.101253
PMCID:
PMC8507197
AbstractArticlePDF–4.0M
6.
Recombinant human bone morphogenetic protein 2 and 7 inhibit the degeneration of intervertebral discs by blocking the Puma-dependent apoptotic signaling
Shiwei Xie, Chenyang Zhao, Wei Chen, Gengwu Li, Zhiwei Xiong, Xiangjun Tang, Fan Zhang, Heng Xiao
Int J Biol Sci. 2021; 17(9): 2367–2379. Published online 2021 Jun 11. doi: 10.7150/ijbs.56823
PMCID:
PMC8241732
AbstractArticlePDF–2.0M
7.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
8.
PUMA facilitates EMI1-promoted cytoplasmic Rad51 ubiquitination and inhibits DNA repair in stem and progenitor cells
Jin Wook Kang, Zhiyan Zhan, Guangzhen Ji, Youzhou Sang, Daohong Zhou, Yanxin Li, Haizhong Feng, Tao Cheng
Signal Transduct Target Ther. 2021; 6: 129. Published online 2021 Mar 31. doi: 10.1038/s41392-021-00510-w
PMCID:
PMC8009889
AbstractArticlePDF–2.3M
9.
The long non-coding RNA TSLC8 inhibits colorectal cancer by stabilizing puma
Zhian Du, Tao Yu, Meina Sun, Yun Chu, Gang Liu
Cell Cycle. 2020; 19(23): 3317–3328. Published online 2020 Nov 20. doi: 10.1080/15384101.2020.1843773
PMCID:
PMC7751665
AbstractArticlePDF–9.3M
10.
Nipped-B-like Protein Sensitizes Esophageal Squamous Cell Carcinoma Cells to Cisplatin via Upregulation of PUMA
Shengjie Zhang, Yun Zhou, Qinchuan Wang, Kristine Donahue, Jianguo Feng, Yinli Yao, Aiping Chen, Xia Li, Lianlian Hong
Technol Cancer Res Treat. 2020; 19: 1533033820960726. Published online 2020 Oct 9. doi: 10.1177/1533033820960726
PMCID:
PMC7592177
AbstractArticlePDF–747K
11.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
AbstractArticlePDF–4.8M
12.
MiR-222-3p Promotes Cell Proliferation and Inhibits Apoptosis by Targeting PUMA (BBC3) in Non-Small Cell Lung Cancer
Weijun Chen, Xiaobo Li
Technol Cancer Res Treat. 2020; 19: 1533033820922558. Published online 2020 Jun 26. doi: 10.1177/1533033820922558
PMCID:
PMC7325542
AbstractArticlePDF–1.1M
13.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
14.
PUMA-mediated epithelial cell apoptosis promotes Helicobacter pylori infection-mediated gastritis
Yini Dang, Yifeng Zhang, Lingyan Xu, Xiaoying Zhou, Yanhong Gu, Jian Yu, Shidai Jin, Haoming Ji, Yongqian Shu, Guoxin Zhang, Shiyun Cui, Jing Sun
Cell Death Dis. 2020 Feb; 11(2): 139. Published online 2020 Feb 20. doi: 10.1038/s41419-020-2339-x
PMCID:
PMC7033162
AbstractArticlePDF–3.0M
15.
Gilteritinib induces PUMA‐dependent apoptotic cell death via AKT/GSK‐3β/NF‐κB pathway in colorectal cancer cells
Liangjun Li, Lin Lin, Ming Li, Weiling Li
J Cell Mol Med. 2020 Feb; 24(3): 2308–2318. Published online 2019 Dec 27. doi: 10.1111/jcmm.14913
PMCID:
PMC7011145
AbstractArticlePDF–1.2M
16.
Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets
Kristen Mengwasser, Richard Adeyemi, Yumei Leng, Mei Yuk Choi, Connor Clairmont, Alan D’Andrea, Stephen J. Elledge
Mol Cell. Author manuscript; available in PMC 2019 Dec 4.
Published in final edited form as: Mol Cell. 2019 Mar 7; 73(5): 885–899.e6. Published online 2019 Jan 24. doi: 10.1016/j.molcel.2018.12.008
PMCID:
PMC6892393
AbstractArticlePDF–1.7M
17.
Long intergenic noncoding RNA-p21 inhibits apoptosis by decreasing PUMA expression in non-small cell lung cancer
Tao Yang, Wenjun Zhang, Li Wang, Chunyan Xiao, Bingling Guo, Yi Gong, Xiping Liang, Dehong Huang, Qiying Li, Yingyu Nan, Ying Xiang, Jianghe Shao
J Int Med Res. 2019 Jan; 47(1): 481–493. Published online 2018 Dec 16. doi: 10.1177/0300060518816592
PMCID:
PMC6384454
AbstractArticlePDF–654K
18.
Puma, a critical mediator of cell death — one decade on from its discovery
Paweł Hikisz, Zofia M. Kiliańska
Cell Mol Biol Lett. 2012 Dec; 17(4): 646–669. Published online 2012 Sep 20. doi: 10.2478/s11658-012-0032-5
PMCID:
PMC6275950
SummaryPDF–601K
19.
Restoring PUMA induction overcomes KRAS-mediated resistance to anti-EGFR antibodies in colorectal cancer
Kyle Knickelbein, Jingshan Tong, Dongshi Chen, Yi-Jun Wang, Sandra Misale, Alberto Bardelli, Jian Yu, Lin Zhang
Oncogene. Author manuscript; available in PMC 2018 Nov 14.
Published in final edited form as: Oncogene. 2018 Aug; 37(33): 4599–4610. Published online 2018 May 14. doi: 10.1038/s41388-018-0289-x
Correction in:
Oncogene. 2023 May 16
PMCID:
PMC6195818
AbstractArticlePDF–750K
20.
Ipatasertib, a novel Akt inhibitor, induces transcription factor FoxO3a and NF-κB directly regulates PUMA-dependent apoptosis
Li Sun, Yuan Huang, Yeying Liu, Yujie Zhao, Xiaoxiao He, Lingling Zhang, Feng Wang, Yingjie Zhang
Cell Death Dis. 2018 Sep; 9(9): 911. Published online 2018 Sep 5. doi: 10.1038/s41419-018-0943-9
PMCID:
PMC6125489
AbstractArticlePDF–1.8M

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