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Select item 107988581.

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking

Lucas J. Marmorale, Huan Jin, Thomas G. Reidy, Brandon Palomino-Alonso, Christopher J. Zysnarski, Fatima Jordan-Javed, Sagar Lahiri, Mara C. Duncan

J Cell Biol. 2024 Mar 4; 223(3): e202309047. Published online 2024 Jan 19. doi: 10.1083/jcb.202309047

PMCID:: PMC10798858

Abstract Article PDF–6.4M

Select item 107001382.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 106812593.

eIF2A represses cell wall biogenesis gene expression in Saccharomyces cerevisiae

Laura Meyer, Baptiste Courtin, Maïté Gomard, Abdelkader Namane, Emmanuelle Permal, Gwenael Badis, Alain Jacquier, Micheline Fromont-Racine

PLoS One. 2023; 18(11): e0293228. Published online 2023 Nov 27. doi: 10.1371/journal.pone.0293228

PMCID:: PMC10681259

Abstract Article PDF–2.5M

Select item 106476994.

A Protein–Protein Interaction Analysis Suggests a Wide Range of New Functions for the p21-Activated Kinase (PAK) Ste20

Ifeoluwapo Matthew Joshua, Meng Lin, Ariestia Mardjuki, Alessandra Mazzola, Thomas Höfken

Int J Mol Sci. 2023 Nov; 24(21): 15916. Published online 2023 Nov 2. doi: 10.3390/ijms242115916

PMCID:: PMC10647699

Abstract Article PDF–5.4M

Select item 104846825.

Paralogous translation factors target distinct mRNAs to differentially regulate tolerance to oxidative stress in yeast

Joanne Cunningham, Aristeidis P Sfakianos, Paraskevi Kritsiligkou, Christopher J Kershaw, Alan J Whitmarsh, Simon J Hubbard, Mark P Ashe, Chris M Grant

Nucleic Acids Res. 2023 Sep 8; 51(16): 8820–8835. Published online 2023 Jul 14. doi: 10.1093/nar/gkad568

PMCID:: PMC10484682

Abstract Article PDF–1.8M

Select item 102977006.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 102333687.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 98643998.

DBP7 and YRF1-6 Are Involved in Cell Sensitivity to LiCl by Regulating the Translation of PGM2 mRNA

Sasi Kumar Jagadeesan, Mustafa Al-gafari, Jiashu Wang, Sarah Takallou, Danielle Allard, Maryam Hajikarimlou, Thomas David Daniel Kazmirchuk, Houman Moteshareie, Kamaledin B. Said, Reza Nokhbeh, Myron Smith, Bahram Samanfar, Ashkan Golshani

Int J Mol Sci. 2023 Jan; 24(2): 1785. Published online 2023 Jan 16. doi: 10.3390/ijms24021785

PMCID:: PMC9864399

Abstract Article PDF–3.4M

Select item 96380289.

Yeast Smy2 and its human homologs GIGYF1 and -2 regulate Cdc48/VCP function during transcription stress

Michelle Harreman Lehner, Jane Walker, Kotryna Temcinaite, Anna Herlihy, Michael Taschner, Adam C. Berger, Anita H. Corbett, A. Barbara Dirac Svejstrup, Jesper Q. Svejstrup

Cell Rep. 2022 Oct 25; 41(4): 111536. Published online 2022 Oct 25. doi: 10.1016/j.celrep.2022.111536

PMCID:: PMC9638028

Abstract Article

Select item 937189210.

mRNA- and factor-driven dynamic variability controls eIF4F-cap recognition for translation initiation

Burak Çetin, Seán E O’Leary

Nucleic Acids Res. 2022 Aug 12; 50(14): 8240–8261. Published online 2022 Jul 25. doi: 10.1093/nar/gkac631

PMCID:: PMC9371892

Abstract Article PDF–5.7M

Select item 924002011.

Lsm7 phase-separated condensates trigger stress granule formation

Michelle Lindström, Lihua Chen, Shan Jiang, Dan Zhang, Yuan Gao, Ju Zheng, Xinxin Hao, Xiaoxue Yang, Arpitha Kabbinale, Johannes Thoma, Lisa C. Metzger, Deyuan Y. Zhang, Xuefeng Zhu, Huisheng Liu, Claes M. Gustafsson, Björn M. Burmann, Joris Winderickx, Per Sunnerhagen, Beidong Liu

Nat Commun. 2022; 13: 3701. Published online 2022 Jun 28. doi: 10.1038/s41467-022-31282-8

PMCID:: PMC9240020

Abstract Article PDF–8.1M

Select item 922654112.

The domains of yeast eIF4G, eIF4E and the cap fine-tune eIF4A activities through an intricate network of stimulatory and inhibitory effects

Linda Krause, Florian Willing, Alexandra Zoi Andreou, Dagmar Klostermeier

Nucleic Acids Res. 2022 Jun 24; 50(11): 6497–6510. Published online 2022 Jun 11. doi: 10.1093/nar/gkac437

PMCID:: PMC9226541

Abstract Article PDF–3.0M

Select item 920981113.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 858383314.

A Multi-Perspective Proximity View on the Dynamic Head Region of the Ribosomal 40S Subunit

Kerstin Schmitt, Alina-Andrea Kraft, Oliver Valerius

Int J Mol Sci. 2021 Nov; 22(21): 11653. Published online 2021 Oct 28. doi: 10.3390/ijms222111653

PMCID:: PMC8583833

Abstract Article PDF–4.2M

Select item 857106315.

Systems-level effects of allosteric perturbations to a model molecular switch

Tina Perica, Christopher J. P. Mathy, Jiewei Xu, Gwendolyn M. Jang, Yang Zhang, Robyn Kaake, Noah Ollikainen, Hannes Braberg, Danielle L. Swaney, David G. Lambright, Mark J. S. Kelly, Nevan J. Krogan, Tanja Kortemme

Nature. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Nature. 2021 Nov; 599(7883): 152–157. Published online 2021 Oct 13. doi: 10.1038/s41586-021-03982-6

PMCID:: PMC8571063

Abstract Article PDF–2.7M

Select item 842121416.

eIF4G is retained on ribosomes elongating and terminating on short upstream ORFs to control reinitiation in yeast

Mahabub Pasha Mohammad, Anna Smirnova, Stanislava Gunišová, Leoš Shivaya Valášek

Nucleic Acids Res. 2021 Sep 7; 49(15): 8743–8756. Published online 2021 Aug 5. doi: 10.1093/nar/gkab652

PMCID:: PMC8421214

Abstract Article PDF–872K

Select item 778024017.

A structural inventory of native ribosomal ABCE1‐43S pre‐initiation complexes

Hanna Kratzat, Timur Mackens‐Kiani, Michael Ameismeier, Mia Potocnjak, Jingdong Cheng, Estelle Dacheux, Abdelkader Namane, Otto Berninghausen, Franz Herzog, Micheline Fromont‐Racine, Thomas Becker, Roland Beckmann

EMBO J. 2021 Jan 4; 40(1): e105179. Published online 2020 Dec 8. doi: 10.15252/embj.2020105179

PMCID:: PMC7780240

Abstract Article PDF–12M

Select item 767243318.

Altered rRNA processing disrupts nuclear RNA homeostasis via competition for the poly(A)-binding protein Nab2

Lisbeth-Carolina Aguilar, Biplab Paul, Taylor Reiter, Louis Gendron, Arvind Arul Nambi Rajan, Rachel Montpetit, Christian Trahan, Sebastian Pechmann, Marlene Oeffinger, Ben Montpetit

Nucleic Acids Res. 2020 Nov 18; 48(20): 11675–11694. Published online 2020 Nov 2. doi: 10.1093/nar/gkaa964