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Select item 103988941.

The E3 ligase Poe promotes Pericentrin degradation

Brian J. Galletta, Ramya Varadarajan, Carey J. Fagerstrom, Bing Yang, Karen Plevock Haase, Katherine McJunkin, Nasser M. Rusan

Mol Biol Cell. 2023 Aug 1; 34(9): br15. Published online 2023 Aug 1. doi: 10.1091/mbc.E22-11-0534

PMCID:: PMC10398894

Abstract Article PDF–4.7M

Select item 102620772.

Toxicity of C9orf72-associated dipeptide repeat peptides is modified by commonly used protein tags

Javier Morón-Oset, Lilly KS Fischer, Mireia Carcolé, Ashling Giblin, Pingze Zhang, Adrian M Isaacs, Sebastian Grönke, Linda Partridge

Life Sci Alliance. 2023 Sep; 6(9): e202201739. Published online 2023 Jun 12. doi: 10.26508/lsa.202201739

PMCID:: PMC10262077

Abstract Article PDF–2.2M

Select item 101057363.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 98457484.

The CRL4 E3 ligase Mahjong/DCAF1 controls cell competition through the transcription factor Xrp1, independently of polarity genes

Amit Kumar, Nicholas E. Baker

Development. 2022 Nov 15; 149(22): dev200795. Published online 2022 Nov 16. doi: 10.1242/dev.200795

PMCID:: PMC9845748

Abstract Article

Select item 95239975.

MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer

Natsumi Tsuboyama, Aileen Patricia Szczepanski, Zibo Zhao, Lu Wang

Genome Biol. 2022; 23: 206. Published online 2022 Sep 30. doi: 10.1186/s13059-022-02776-x

PMCID:: PMC9523997

Abstract Article PDF–6.9M

Select item 86644866.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 84688277.

Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders

Stefano Sechi, Angela Karimpour-Ghahnavieh, Anna Frappaolo, Laura Di Francesco, Roberto Piergentili, Eugenia Schininà, Pier Paolo D’Avino, Maria Grazia Giansanti

Cells. 2021 Sep; 10(9): 2336. Published online 2021 Sep 6. doi: 10.3390/cells10092336

PMCID:: PMC8468827

Abstract Article PDF–4.1M

Select item 81724688.

Proteasome Stress in Skeletal Muscle Mounts a Long-Range Protective Response that Delays Retinal and Brain Aging

Mamta Rai, Zane Coleman, Michelle Curley, Anjana Nityanandam, Anna Platt, Maricela Robles-Murguia, Jianqin Jiao, David Finkelstein, Yong-Dong Wang, Beisi Xu, Yiping Fan, Fabio Demontis

Cell Metab. Author manuscript; available in PMC 2022 Jun 1.

Published in final edited form as: Cell Metab. 2021 Jun 1; 33(6): 1137–1154.e9. Published online 2021 Mar 26. doi: 10.1016/j.cmet.2021.03.005

PMCID:: PMC8172468

Abstract Article PDF–4.2M

Select item 77872589.

Prolonged Exposure to Microgravity Reduces Cardiac Contractility and Initiates Remodeling in Drosophila

Stanley Walls, Soda Diop, Ryan Birse, Lisa Elmen, Zhuohui Gan, Sreehari Kalvakuri, Santiago Pineda, Curran Reddy, Erika Taylor, Bosco Trinh, Georg Vogler, Rachel Zarndt, Andrew McCulloch, Peter Lee, Sharmila Bhattacharya, Rolf Bodmer, Karen Ocorr

Cell Rep. Author manuscript; available in PMC 2021 Jan 6.

Published in final edited form as: Cell Rep. 2020 Dec 8; 33(10): 108445. Published online 2020 Nov 25. doi: 10.1016/j.celrep.2020.108445

PMCID:: PMC7787258

Abstract Article PDF–1.5M

Select item 738485610.

The E2 Marie Kondo and the CTLH E3 ligase clear deposited RNA binding proteins during the maternal-to-zygotic transition

Michael Zavortink, Lauren N Rutt, Svetlana Dzitoyeva, Jesslyn C Henriksen, Chloe Barrington, Danielle Y Bilodeau, Miranda Wang, Xiao Xiao Lily Chen, Olivia S Rissland

eLife. 2020; 9: e53889. Published online 2020 Jun 23. doi: 10.7554/eLife.53889

PMCID:: PMC7384856

Abstract Article PDF–4.5M

Select item 736935411.

Rpt2 proteasome subunit reduction causes Parkinson's disease like symptoms in Drosophila

Iván Fernández-Cruz, Iván Sánchez-Díaz, Verónica Narváez-Padilla, Enrique Reynaud

IBRO Rep. 2020 Dec; 9: 65–77. Published online 2020 Jul 11. doi: 10.1016/j.ibror.2020.07.001

PMCID:: PMC7369354

Abstract Article PDF–2.8M

Select item 709642512.

Proteomic mapping of Drosophila transgenic elav.L-GAL4/+ brain as a tool to illuminate neuropathology mechanisms

Athanassios D. Velentzas, Stamatia A. Katarachia, Niki E. Sagioglou, Maria M. Tsioka, Athanasios K. Anagnostopoulos, Vassiliki E. Mpakou, Eleni I. Theotoki, Aikaterini F. Giannopoulou, Konstantinos E. Keramaris, Issidora S. Papassideri, George Th. Tsangaris, Dimitrios J. Stravopodis

Sci Rep. 2020; 10: 5430. Published online 2020 Mar 25. doi: 10.1038/s41598-020-62510-0

PMCID:: PMC7096425

Abstract Article PDF–4.6M

Select item 696157813.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 683491114.

Differential toxicity of ataxin-3 isoforms in Drosophila models of Spinocerebellar Ataxia Type 3

Sean L. Johnson, Jessica R. Blount, Kozeta Libohova, Bedri Ranxhi, Henry L. Paulson, Wei-Ling Tsou, Sokol V. Todi

Neurobiol Dis. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Neurobiol Dis. 2019 Dec; 132: 104535. Published online 2019 Jul 13. doi: 10.1016/j.nbd.2019.104535

PMCID:: PMC6834911

Abstract Article PDF–3.3M

Select item 675092615.

Large-scale RNAi screen identified Dhpr as a regulator of mitochondrial morphology and tissue homeostasis

Jia Zhou, Lingna Xu, Xiuying Duan, Wei Liu, Xiaocui Zhao, Xi Wang, Weina Shang, Xuefei Fang, Huan Yang, Lijun Jia, Jian Bai, Jiayao Zhao, Liquan Wang, Chao Tong

Sci Adv. 2019 Sep; 5(9): eaax0365. Published online 2019 Sep 18. doi: 10.1126/sciadv.aax0365

PMCID:: PMC6750926

Abstract Article PDF–14M

Select item 639850116.

SOD1 activity threshold and TOR signalling modulate VAP(P58S) aggregation via reactive oxygen species-induced proteasomal degradation in a Drosophila model of amyotrophic lateral sclerosis

Kriti Chaplot, Lokesh Pimpale, Balaji Ramalingam, Senthilkumar Deivasigamani, Siddhesh S. Kamat, Girish S. Ratnaparkhi

Dis Model Mech. 2019 Feb 1; 12(2): dmm033803. Published online 2019 Feb 7. doi: 10.1242/dmm.033803

PMCID:: PMC6398501

Abstract Article

Select item 607860417.

Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson’s disease

Md Shariful Islam, Hendrik Nolte, Wright Jacob, Anna B. Ziegler, Stefanie Pütz, Yael Grosjean, Karolina Szczepanowska, Aleksandra Trifunovic, Thomas Braun, Hermann Heumann, Rolf Heumann, Bernhard Hovemann, Darren J. Moore, Marcus Krüger

Hum Mol Genet. 2016 Dec 15; 25(24): 5365–5382. Published online 2016 Oct 29. doi: 10.1093/hmg/ddw352

PMCID:: PMC6078604

Abstract Article PDF–1.9M

Select item 598915718.

An RNAi-mediated screen identifies novel targets for next-generation antiepileptic drugs based on increased expression of the homeostatic regulator pumilio

Wei-Hsiang Lin, Miaomiao He, Yuen Ngan Fan, Richard A. Baines

J Neurogenet. 2018; 32(2): 106–117. Published online 2018 May 2. doi: 10.1080/01677063.2018.1465570

PMCID:: PMC5989157

Abstract Article PDF–1.5M

Select item 598147019.

Expression and Regulation of Deubiquitinase-Resistant, Unanchored Ubiquitin Chains in Drosophila

Jessica R. Blount, Kozeta Libohova, Gregory B. Marsh, Joanna R. Sutton, Sokol V. Todi

Sci Rep. 2018; 8: 8513. Published online 2018 May 31. doi: 10.1038/s41598-018-26364-x

PMCID:: PMC5981470

Abstract Article PDF–4.1M

Select item 593605620.

The Drosophila TGF-beta/Activin-like ligands Dawdle and Myoglianin appear to modulate adult lifespan through regulation of 26S proteasome function in adult muscle

Shaughna Langerak, Myung-Jun Kim, Hannah Lamberg, Michael Godinez, Mackenzie Main, Lindsey Winslow, Michael B. O'Connor, Changqi C. Zhu

Biol Open. 2018 Apr 15; 7(4): bio029454. Published online 2018 Apr 3. doi: 10.1242/bio.029454

PMCID:: PMC5936056

Abstract Article PDF–3.3M

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