PMC Links for GEO Profiles (Select 37637382) - PMC

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 82218134.

Robustness of epithelial sealing is an emerging property of local ERK feedback driven by cell elimination

Léo Valon, Anđela Davidović, Florence Levillayer, Alexis Villars, Mathilde Chouly, Fabiana Cerqueira-Campos, Romain Levayer

Dev Cell. 2021 Jun 21; 56(12): 1700–1711.e8. doi: 10.1016/j.devcel.2021.05.006

PMCID:: PMC8221813

Abstract Article

Select item 80229465.

An RNAi screen of the kinome in epithelial follicle cells of the Drosophila melanogaster ovary reveals genes required for proper germline death and clearance

Diane P V Lebo, Alice Chirn, Jeffrey D Taylor, Andre Levan, Valentina Doerre Torres, Emily Agreda, Sandy B Serizier, Allison K Lord, Victoria K Jenkins, Kimberly McCall

G3 (Bethesda) 2021 Feb; 11(2): jkaa066. Published online 2021 Mar 6. doi: 10.1093/g3journal/jkaa066

PMCID:: PMC8022946

Abstract Article PDF–1.3M

Select item 79730986.

Kinome-Wide RNAi Screen Uncovers Role of Ballchen in Maintenance of Gene Activation by Trithorax Group in Drosophila

Muhammad Haider Farooq Khan, Jawad Akhtar, Zain Umer, Najma Shaheen, Ammad Shaukat, Muhammad Shahbaz Munir, Aziz Mithani, Saima Anwar, Muhammad Tariq

Front Cell Dev Biol. 2021; 9: 637873. Published online 2021 Mar 5. doi: 10.3389/fcell.2021.637873

PMCID:: PMC7973098

Abstract Article PDF–2.2M

Select item 78428937.

Epithelial cell-turnover ensures robust coordination of tissue growth in Drosophila ribosomal protein mutants

Nanami Akai, Shizue Ohsawa, Yukari Sando, Tatsushi Igaki

PLoS Genet. 2021 Jan; 17(1): e1009300. Published online 2021 Jan 28. doi: 10.1371/journal.pgen.1009300

PMCID:: PMC7842893

Abstract Article PDF–3.8M

Select item 66731378.

Neuronal Morphogenesis Is Regulated by the Interplay between Cyclin-Dependent Kinase 5 and the Ubiquitin Ligase Mind Bomb 1

Eun-Ah Choe, Lujian Liao, Jian-Ying Zhou, Dongmei Cheng, Duc M. Duong, Peng Jin, Li-Huei Tsai, Junmin Peng

J Neurosci. 2007 Aug 29; 27(35): 9503–9512. doi: 10.1523/JNEUROSCI.1408-07.2007

PMCID:: PMC6673137

Abstract Article PDF–24M

Select item 66160139.

Expression of a fragment of Ankyrin 2 disrupts the structure of the Axon Initial Segment and causes axonal degeneration in Drosophila

Joshua Spurrier, Arvind Kumar Shukla, Tyler Buckley, Svetlana Smith-Trunova, Irina Kuzina, Qun Gu, Edward Giniger

Mol Neurobiol. Author manuscript; available in PMC 2020 Aug 1.

Published in final edited form as: Mol Neurobiol. 2019 Aug; 56(8): 5689–5700. Published online 2019 Jan 21. doi: 10.1007/s12035-019-1477-6

PMCID:: PMC6616013

Abstract Article PDF–936K

Select item 654822710.

Cross-species genetic screens to identify kinase targets for APP reduction in Alzheimer's disease

Claudia H Huichalaf, Ismael Al-Ramahi, Kyung-Won Park, Stacy D Grunke, Nan Lu, Maria de Haro, Karla El-Zein, Tatiana Gallego-Flores, Alma M Perez, Sung Yun Jung, Juan Botas, Huda Y Zoghbi, Joanna L Jankowsky

Hum Mol Genet. 2019 Jun 15; 28(12): 2014–2029. Published online 2019 Feb 12. doi: 10.1093/hmg/ddz034

PMCID:: PMC6548227

Abstract Article PDF–24M

Select item 644247311.

Hyperactive Innate Immunity Causes Degeneration of Dopamine Neurons upon Altering Activity of Cdk5

Arvind Kumar Shukla, Joshua Spurrier, Irina Kuzina, Edward Giniger

Cell Rep. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: Cell Rep. 2019 Jan 2; 26(1): 131–144.e4. doi: 10.1016/j.celrep.2018.12.025

Correction in:: Cell Rep. 2021 Jun 8; 35(10): 109258.

PMCID:: PMC6442473

Abstract Article PDF–2.7M

Select item 608240112.

High-throughput functional analysis distinguishes pathogenic, nonpathogenic, and compensatory transcriptional changes in a neurodegenerative disorder

Ismael Al-Ramahi, Boxun Lu, Simone Di Paola, Kaifang Pang, Maria de Haro, Ivana Peluso, Tatiana Gallego-Flores, Nazish T. Malik, Kelly Erikson, Benjamin A. Bleiberg, Matthew Avalos, George Fan, Laura Elizabeth Rivers, Andrew M. Laitman, Javier R. Diaz-García, Marc Hild, James Palacino, Zhandong Liu, Diego L. Medina, Juan Botas

Cell Syst. Author manuscript; available in PMC 2019 Jul 25.

Published in final edited form as: Cell Syst. 2018 Jul 25; 7(1): 28–40.e4. Published online 2018 Jun 20. doi: 10.1016/j.cels.2018.05.010

PMCID:: PMC6082401

Abstract Article PDF–2.3M

Select item 598725413.

CDK5 Inhibition Resolves PKA/cAMP-Independent Activation of CREB1 Signaling in Glioma Stem Cells

Subhas Mukherjee, Carol Tucker-Burden, Emily Kaissi, Austin Newsam, Hithardhi Duggireddy, Monica Chau, Changming Zhang, Bhakti Diwedi, Manali Rupji, Sandra Seby, Jeanne Kowalski, Jun Kong, Renee Read, Daniel J. Brat

Cell Rep. Author manuscript; available in PMC 2018 Jun 5.

Published in final edited form as: Cell Rep. 2018 May 8; 23(6): 1651–1664. doi: 10.1016/j.celrep.2018.04.016

PMCID:: PMC5987254

Abstract Article PDF–2.0M

Select item 589772214.

Altered expression of the Cdk5 activator-like protein, Cdk5α, causes neurodegeneration, in part by accelerating the rate of aging

Joshua Spurrier, Arvind Kumar Shukla, Kristina McLinden, Kory Johnson, Edward Giniger

Dis Model Mech. 2018 Mar 1; 11(3): dmm031161. doi: 10.1242/dmm.031161

PMCID:: PMC5897722

Abstract Article

Select item 576020615.

Stress-induced Cdk5 activity enhances cytoprotective basal autophagy in Drosophila melanogaster by phosphorylating acinus at serine⁴³⁷

Nilay Nandi, Lauren K Tyra, Drew Stenesen, Helmut Krämer

eLife. 2017; 6: e30760. Published online 2017 Dec 11. doi: 10.7554/eLife.30760

PMCID:: PMC5760206

Abstract Article PDF–11M

Select item 570780516.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900217.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 471551118.

Cdk5 regulates developmental remodeling of mushroom body neurons in Drosophila

Svetlana Smith-Trunova, Ranjini Prithviraj, Joshua Spurrier, Irina Kuzina, Qun Gu, Edward Giniger

Dev Dyn. Author manuscript; available in PMC 2016 Dec 1.

Published in final edited form as: Dev Dyn. 2015 Dec; 244(12): 1550–1563. Published online 2015 Oct 14. doi: 10.1002/dvdy.24350

PMCID:: PMC4715511

Abstract Article PDF–1.1M

Select item 464270919.

Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi

Benjamin E. Housden, Alexander J. Valvezan, Colleen Kelley, Richelle Sopko, Yanhui Hu, Charles Roesel, Shuailiang Lin, Michael Buckner, Rong Tao, Bahar Yilmazel, Stephanie E. Mohr, Brendan D. Manning, Norbert Perrimon

Sci Signal. Author manuscript; available in PMC 2016 Mar 8.

Published in final edited form as: Sci Signal. 2015; 8(393): rs9. Published online 2015 Sep 8. doi: 10.1126/scisignal.aab3729

PMCID:: PMC4642709

Abstract Article PDF–959K

Select item 452833020.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

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