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Select item 110332421.

A novel mouse model for familial hypocalciuric hypercalcemia (FHH1) reveals PTH-dependent and independent CaSR defects

Catharina J. Küng, Arezoo Daryadel, Rocio Fuente, Betül Haykir, Martin Hrabĕ de Angelis, Nati Hernando, Isabel Rubio-Aliaga, Carsten A. Wagner

Pflugers Arch. 2024; 476(5): 833–845. Published online 2024 Feb 22. doi: 10.1007/s00424-024-02927-y

PMCID:: PMC11033242

Abstract Article PDF–6.5M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 101718603.

PTH regulates osteogenesis and suppresses adipogenesis through Zfp467 in a feed-forward, PTH1R-cyclic AMP-dependent manner

Hanghang Liu, Akane Wada, Isabella Le, Phuong T Le, Andrew WF Lee, Jun Zhou, Francesca Gori, Roland Baron, Clifford J Rosen

eLife. 2023; 12: e83345. Published online 2023 Apr 26. doi: 10.7554/eLife.83345

PMCID:: PMC10171860

Abstract Article PDF–11M

Select item 98256654.

Conditional Loss of Nmp4 in Mesenchymal Stem Progenitor Cells Enhances PTH-Induced Bone Formation

Emily G. Atkinson, Michele Adaway, Daniel J. Horan, Crystal Korff, Angela Klunk, Ashley L. Orr, Katherine Ratz, Teresita Bellido, Lilian I. Plotkin, Alexander G. Robling, Joseph P. Bidwell

J Bone Miner Res. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: J Bone Miner Res. 2023 Jan; 38(1): 70–85. Published online 2022 Nov 22. doi: 10.1002/jbmr.4732

PMCID:: PMC9825665

Abstract Article PDF–2.9M

Select item 90454605.

Gender-Specific Differences in the Skeletal Response to Continuous PTH in Mice Lacking the IGF1 Receptor in Mature Osteoblasts

Muriel Babey, Yongmei Wang, Takuo Kubota, Chak Fong, Alicia Menendez, Hashem Z ElAlieh, Daniel D Bikle

J Bone Miner Res. Author manuscript; available in PMC 2022 Apr 27.

Published in final edited form as: J Bone Miner Res. 2015 Jun; 30(6): 1064–1076. doi: 10.1002/jbmr.2433

PMCID:: PMC9045460

Abstract Article PDF–2.8M

Select item 87667966.

Exogenous PTH 1-34 Attenuates Impaired Fracture Healing in Endogenous PTH Deficiency Mice via Activating Indian Hedgehog Signaling Pathway and Accelerating Endochondral Ossification

Cheng Ma, Huan Liu, Yifan Wei, He Li, Dengshun Miao, Yongxin Ren

Front Cell Dev Biol. 2021; 9: 750878. Published online 2022 Jan 5. doi: 10.3389/fcell.2021.750878

PMCID:: PMC8766796

Abstract Article PDF–3.9M

Select item 85967987.

Anabolic actions of PTH in murine models: two decades of insights

Laura E. Zweifler, Amy J. Koh, Stephanie Daignault‐Newton, Laurie K. McCauley

J Bone Miner Res. 2021 Oct; 36(10): 1979–1998. Published online 2021 Jul 27. doi: 10.1002/jbmr.4389

PMCID:: PMC8596798

Abstract Article PDF–933K

Select item 78647488.

Purinergic Signaling Mediates PTH and Fluid Flow-Induced Osteoblast Proliferation

Yanghui Xing, Liang Song, Yingying Zhang, Tengyu Zhang, Jian Li, Chunjing Tao

Biomed Res Int. 2021; 2021: 6674570. Published online 2021 Jan 27. doi: 10.1155/2021/6674570

PMCID:: PMC7864748

Abstract Article PDF–1.0M

Select item 70144729.

The Rho GTPase RAC1 in Osteoblasts Controls Their Function

Katrin Huck, Carla Sens, Carina Wuerfel, Caren Zoeller, Inaam A. Nakchbandi

Int J Mol Sci. 2020 Jan; 21(2): 385. Published online 2020 Jan 8. doi: 10.3390/ijms21020385

PMCID:: PMC7014472

Abstract Article PDF–2.5M

Select item 654486710.

Deficiency in the secreted protein Semaphorin3d causes abnormal parathyroid development in mice

Anamika Singh, Masum M. Mia, Dasan Mary Cibi, Ashutosh Kumar Arya, Sanjay Kumar Bhadada, Manvendra K. Singh

J Biol Chem. 2019 May 24; 294(21): 8336–8347. Published online 2019 Apr 12. doi: 10.1074/jbc.RA118.007063

PMCID:: PMC6544867

Abstract Article PDF–4.4M

Select item 645951011.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Abstract Article PDF–5.1M

Select item 634546112.

Gcm2 regulates the maintenance of parathyroid cells in adult mice

Taku Yamada, Norifumi Tatsumi, Akane Anraku, Hideaki Suzuki, Sahoko Kamejima, Taketo Uchiyama, Ichiro Ohkido, Takashi Yokoo, Masataka Okabe

PLoS One. 2019; 14(1): e0210662. Published online 2019 Jan 24. doi: 10.1371/journal.pone.0210662

PMCID:: PMC6345461

Abstract Article PDF–2.2M

Select item 629329513.

In vivo evidence for an interplay of FGF23/Klotho/PTH axis on the phosphate handling in renal proximal tubules

Noriko Ide, Rui Ye, Marie Courbebaisse, Hannes Olauson, Michael J. Densmore, Tobias E. Larsson, Jun-ichi Hanai, Beate Lanske

Am J Physiol Renal Physiol. 2018 Nov 1; 315(5): F1261–F1270. Published online 2018 Jul 11. doi: 10.1152/ajprenal.00650.2017

PMCID:: PMC6293295

Abstract Article

Select item 597988714.

Lack of endogenous parathyroid hormone delays fracture healing by inhibiting vascular endothelial growth factor-mediated angiogenesis

Qingfeng Ding, Peng Sun, Hao Zhou, Bowen Wan, Jian Yin, Yao Huang, Qingqing Li, Guoyong Yin, Jin Fan

Int J Mol Med. 2018 Jul; 42(1): 171–181. Published online 2018 Apr 3. doi: 10.3892/ijmm.2018.3614

PMCID:: PMC5979887

Abstract Article PDF–1.0M

Select item 559385115.

The parathyroid hormone regulates skin tumour susceptibility in mice

Kazuhiro Okumura, Megumi Saito, Yasuhiro Yoshizawa, Haruka Munakata, Eriko Isogai, Ikuo Miura, Shigeharu Wakana, Midori Yamaguchi, Hiroshi Shitara, Choji Taya, Andrew C. Karaplis, Ryo Kominami, Yuichi Wakabayashi

Sci Rep. 2017; 7: 11208. Published online 2017 Sep 11. doi: 10.1038/s41598-017-11561-x

PMCID:: PMC5593851

Abstract Article PDF–9.5M

Select item 541307516.

FGF23 Is Not Required to Regulate Fetal Phosphorus Metabolism but Exerts Effects Within 12 Hours After Birth

Yue Ma, Beth J. Kirby, Nicholas A. Fairbridge, Andrew C. Karaplis, Beate Lanske, Christopher S. Kovacs

Endocrinology. 2017 Feb 1; 158(2): 252–263. Published online 2016 Dec 8. doi: 10.1210/en.2016-1369

PMCID:: PMC5413075

Abstract Article

Select item 486734917.

Pathogenic role of calcium-sensing receptors in the development and progression of pulmonary hypertension

Haiyang Tang, Aya Yamamura, Hisao Yamamura, Shanshan Song, Dustin R. Fraidenburg, Jiwang Chen, Yali Gu, Nicole M. Pohl, Tong Zhou, Laura Jiménez-Pérez, Ramon J. Ayon, Ankit A. Desai, David Goltzman, Franz Rischard, Zain Khalpey, Stephan M. Black, Joe G. N. Garcia, Ayako Makino, Jason X. J. Yuan

Am J Physiol Lung Cell Mol Physiol. 2016 May 1; 310(9): L846–L859. Published online 2016 Mar 11. doi: 10.1152/ajplung.00050.2016

PMCID:: PMC4867349

Abstract Article

Select item 485653718.

Calcium sensing receptor function supports osteoblast survival and acts as a co-factor in PTH anabolic actions in bone

Saja A. Al-Dujaili, Amy J. Koh, Ming Dang, Xue Mi, Wenhan Chang, Peter X. Ma, Laurie K. McCauley

J Cell Biochem. Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: J Cell Biochem. 2016 Jul; 117(7): 1556–1567. Published online 2016 Feb 19. doi: 10.1002/jcb.25447

PMCID:: PMC4856537

Abstract Article PDF–1.4M

Select item 483521719.

Deletion of the distal Tnfsf11 RL-D2 enhancer that contributes to PTH-mediated RANKL expression in osteoblast lineage cells results in a high bone mass phenotype in mice

M. Onal, H.C. St John, A.L. Danielson, J.W. Pike

J Bone Miner Res. Author manuscript; available in PMC 2017 Feb 1.

Published in final edited form as: J Bone Miner Res. 2016 Feb; 31(2): 416–429. doi: 10.1002/jbmr.2698

PMCID:: PMC4835217

Abstract Article PDF–1.5M

Select item 477942920.

Selective Regulation of Mmp13 by 1,25(OH)₂D₃, PTH, and Osterix through Distal Enhancers

Mark B. Meyer, Nancy A. Benkusky, Melda Onal, J. Wesley Pike

J Steroid Biochem Mol Biol. Author manuscript; available in PMC 2017 Nov 1.

Published in final edited form as: J Steroid Biochem Mol Biol. 2016 Nov; 164: 258–264. Published online 2015 Sep 5. doi: 10.1016/j.jsbmb.2015.09.001

PMCID:: PMC4779429

Abstract Article PDF–789K

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