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Select item 112258091.

DUSP6 deletion protects mice and reduces disease severity in autoimmune arthritis

Teresina Laragione, Carolyn Harris, Natasha Rice, Percio S. Gulko

iScience. 2024 Jun 21; 27(6): 110158. Published online 2024 May 31. doi: 10.1016/j.isci.2024.110158

PMCID:: PMC11225809

Abstract Article PDF–3.9M

Select item 109464402.

Sall4 regulates posterior trunk mesoderm development by promoting mesodermal gene expression and repressing neural genes in the mesoderm

Matthew P. Pappas, Hiroko Kawakami, Dylan Corcoran, Katherine Q. Chen, Earl Parker Scott, Julia Wong, Micah D. Gearhart, Ryuichi Nishinakamura, Yasushi Nakagawa, Yasuhiko Kawakami

Development. 2024 Mar 1; 151(5): dev202649. Published online 2024 Mar 4. doi: 10.1242/dev.202649

PMCID:: PMC10946440

Abstract Article

Select item 109379573.

Intestinal dual-specificity phosphatase 6 regulates the cold-induced gut microbiota remodeling to promote white adipose browning

Pei-Chen Chen, Tzu-Pei Tsai, Yi-Chu Liao, Yu-Chieh Liao, Hung-Wei Cheng, Yi-Hsiu Weng, Chiao-Mei Lin, Cheng-Yuan Kao, Chih-Cheng Tai, Jhen-Wei Ruan

NPJ Biofilms Microbiomes. 2024; 10: 22. Published online 2024 Mar 13. doi: 10.1038/s41522-024-00495-8

PMCID:: PMC10937957

Abstract Article PDF–3.4M

Select item 107424704.

Dual-Specificity Phosphatase 6 Deficiency Attenuates Arterial-Injury-Induced Intimal Hyperplasia in Mice

Candra D. Hamdin, Meng-Ling Wu, Chen-Mei Chen, Yen-Chun Ho, Wei-Cheng Jiang, Pei-Yu Gung, Hua-Hui Ho, Huai-Chia Chuang, Tse-Hua Tan, Shaw-Fang Yet

Int J Mol Sci. 2023 Dec; 24(24): 17136. Published online 2023 Dec 5. doi: 10.3390/ijms242417136

PMCID:: PMC10742470

Abstract Article PDF–4.8M

Select item 106473895.

Acute Endoplasmic Reticulum Stress Suppresses Hepatic Gluconeogenesis by Stimulating MAPK Phosphatase 3 Degradation

Xiaohua Huang, Heng Zhu, Wei Lu, Lei Cao, Zhengfeng Fang, Lianqiang Che, Yan Lin, Shengyu Xu, Yong Zhuo, Lun Hua, Xuemei Jiang, Mengmeng Sun, De Wu, Bin Feng

Int J Mol Sci. 2023 Nov; 24(21): 15561. Published online 2023 Oct 25. doi: 10.3390/ijms242115561

PMCID:: PMC10647389

Abstract Article PDF–8.4M

Select item 106368946.

Identification of DUSP4/6 overexpression as a potential rheostat to NRAS-induced hepatocarcinogenesis

Sophie Klemm, Katja Evert, Kirsten Utpatel, Alexandra Muggli, Maria M. Simile, Xin Chen, Matthias Evert, Diego F. Calvisi, Alexander Scheiter

BMC Cancer. 2023; 23: 1086. Published online 2023 Nov 9. doi: 10.1186/s12885-023-11577-9

PMCID:: PMC10636894

Abstract Article PDF–4.0M

Select item 104036407.

Feto-maternal cholesterol transport regulated by β-Klotho–FGF15 axis is essential for fetal growth

Kanako Kobayashi, Kazuko Iwasa, Rika Azuma-Suzuki, Takeshi Kawauchi, Yo-ichi Nabeshima

Life Sci Alliance. 2023 Oct; 6(10): e202301916. Published online 2023 Aug 4. doi: 10.26508/lsa.202301916

PMCID:: PMC10403640

Abstract Article PDF–2.1M

Select item 101779748.

DUSP6 Deficiency Attenuates Neurodegeneration after Global Cerebral Ischemia

Yi-Chinn Weng, Yu-Ting Huang, I-Chen Chiang, Huai-Chia Chuang, Tsong-Hai Lee, Tse-Hua Tan, Wen-Hai Chou

Int J Mol Sci. 2023 May; 24(9): 7690. Published online 2023 Apr 22. doi: 10.3390/ijms24097690

PMCID:: PMC10177974

Abstract Article PDF–3.5M

Select item 101087069.

A distinct transcriptome characterizes neural crest-derived cells at the migratory wavefront during enteric nervous system development

Rhian Stavely, Ryo Hotta, Richard A. Guyer, Nicole Picard, Ahmed A. Rahman, Meredith Omer, Adam Soos, Emoke Szocs, Jessica Mueller, Allan M. Goldstein, Nandor Nagy

Development. 2023 Mar 1; 150(5): dev201090. Published online 2023 Mar 6. doi: 10.1242/dev.201090

PMCID:: PMC10108706

Abstract Article

Select item 993700710.

LncTUG1 ameliorates renal tubular fibrosis in experimental diabetic nephropathy through the miR-145-5p/dual-specificity phosphatase 6 axis

Taoxia Wang, Shubei Cui, Xiaoli Liu, Li Han, Xiaoting Duan, Shuning Feng, Sen Zhang, Guiying Li

Ren Fail. 2023; 45(1): 2173950. Published online 2023 Feb 16. doi: 10.1080/0886022X.2023.2173950

PMCID:: PMC9937007

Abstract Article PDF–3.2M

Select item 963710311.

Dusp6 deficiency attenuates neutrophil-mediated cardiac damage in the acute inflammatory phase of myocardial infarction

Xiaohai Zhou, Chenyang Zhang, Xueying Wu, Xinli Hu, Yan Zhang, Xuelian Wang, Lixia Zheng, Peng Gao, Jianyong Du, Wen Zheng, Haibao Shang, Keping Hu, Zhengfan Jiang, Yu Nie, Shengshou Hu, Rui-Ping Xiao, Xiaojun Zhu, Jing-Wei Xiong

Nat Commun. 2022; 13: 6672. Published online 2022 Nov 5. doi: 10.1038/s41467-022-33631-z

PMCID:: PMC9637103

Abstract Article PDF–4.2M

Select item 930434112.

Etv2 regulates enhancer chromatin status to initiate Shh expression in the limb bud

Naoko Koyano-Nakagawa, Wuming Gong, Satyabrata Das, Joshua W. M. Theisen, Tran B. Swanholm, Daniel Van Ly, Nikita Dsouza, Bhairab N. Singh, Hiroko Kawakami, Samantha Young, Katherine Q. Chen, Yasuhiko Kawakami, Daniel J. Garry

Nat Commun. 2022; 13: 4221. Published online 2022 Jul 21. doi: 10.1038/s41467-022-31848-6

PMCID:: PMC9304341

Abstract Article PDF–5.7M

Select item 910658013.

Suppression of mutant Kirsten-RAS (KRAS^G12D)-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 6

Andrew M. Kidger, Mark K. Saville, Linda K. Rushworth, Jane Davidson, Julia Stellzig, Motoharu Ono, Ludwig A. Kuebelsbeck, Klaus-Peter Janssen, Bernhard Holzmann, Jennifer P. Morton, Owen J. Sansom, Christopher J. Caunt, Stephen M. Keyse

Oncogene. 2022; 41(20): 2811–2823. Published online 2022 Apr 13. doi: 10.1038/s41388-022-02302-0

PMCID:: PMC9106580

Abstract Article PDF–6.0M

Select item 893053714.

Candidate positive targets of LHX6 and LHX8 transcription factors in the developing upper jaw

Jeffry Cesario, Sara Ha, Julie Kim, Niam Kataria, Juhee Jeong

Gene Expr Patterns. Author manuscript; available in PMC 2023 Mar 1.

Published in final edited form as: Gene Expr Patterns. 2022 Mar; 43: 119227. Published online 2021 Nov 30. doi: 10.1016/j.gep.2021.119227

PMCID:: PMC8930537

Abstract Article PDF–1.8M

Select item 880001415.

Single-cell RNA sequencing uncovers the individual alteration of intestinal mucosal immunocytes in Dusp6 knockout mice

Cherng-Shyang Chang, Wen-Hsuan Yu, Chang-Chao Su, Jhen-Wei Ruan, Chiao-Mei Lin, Chih-Ting Huang, Yi-Ting Tsai, I-Jung Lin, Chao-Yang Lai, Tsung-Hsien Chuang, Wen-Jye Lin, Tse-Hua Tan, Hsuan-Cheng Huang, Hsueh-Fen Juan, Cheng-Yuan Kao

iScience. 2022 Feb 18; 25(2): 103738. Published online 2022 Jan 7. doi: 10.1016/j.isci.2022.103738