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Select item 110721451.

Mechanosensors control skeletal muscle mass, molecular clocks, and metabolism

Mathias Vanmunster, Ana Victoria Rojo Garcia, Alexander Pacolet, Sebastiaan Dalle, Katrien Koppo, Ilse Jonkers, Rik Lories, Frank Suhr

Cell Mol Life Sci. 2022 Jun; 79(6): 321. Published online 2022 May 27. doi: 10.1007/s00018-022-04346-7

PMCID:: PMC11072145

Abstract Article PDF–1.6M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108312593.

Kindlin-2 maintains liver homeostasis by regulating GSTP1–OPN-mediated oxidative stress and inflammation in mice

Yiming Zhong, Liang Zhou, Hui Wang, Sixiong Lin, Tiemin Liu, Xingxing Kong, Guozhi Xiao, Huanqing Gao

J Biol Chem. 2024 Feb; 300(2): 105601. Published online 2023 Dec 28. doi: 10.1016/j.jbc.2023.105601

Correction in:: J Biol Chem. 2024 Mar; 300(3): 105738.

PMCID:: PMC10831259

Abstract Article PDF–4.8M

Select item 105760464.

Kindlin-2 in myoepithelium controls luminal progenitor commitment to alveoli in mouse mammary gland

Zhenbin Wang, Lei Zhang, Bing Li, Jiagui Song, Miao Yu, Jing Zhang, Ceshi Chen, Jun Zhan, Hongquan Zhang

Cell Death Dis. 2023 Oct; 14(10): 675. Published online 2023 Oct 13. doi: 10.1038/s41419-023-06184-2

PMCID:: PMC10576046

Abstract Article PDF–8.9M

Select item 104652185.

Kindlin-2 enhances c-Myc translation through association with DDX3X to promote pancreatic ductal adenocarcinoma progression

Chengmin Liu, Ke Jiang, Yanyan Ding, Aihua Yang, Renwei Cai, Panzhu Bai, Minggang Xiong, Changying Fu, Meiling Quan, Zailin Xiong, Yi Deng, Ruijun Tian, Chuanyue Wu, Ying Sun

Theranostics. 2023; 13(13): 4333–4355. Published online 2023 Jul 31. doi: 10.7150/thno.85421

PMCID:: PMC10465218

Abstract Article PDF–10M

Select item 102449016.

Comparison of Kindlin-2 deficiency-stimulated osteoarthritis-like lesions induced by Prg4^CreERT2 versus Aggrecan^CreERT2 transgene in mice

Qing Yao, Weiyuan Gong, Xiaohao Wu, Donghao Gan, Chu Tao, Sixiong Lin, Minghao Qu, Zhongtian Ouyang, Mingjue Chen, Xinjia Hu, Guozhi Xiao

J Orthop Translat. 2023 Jul; 41: 12–19. Published online 2023 May 31. doi: 10.1016/j.jot.2023.05.005

PMCID:: PMC10244901

Abstract Article PDF–3.2M

Select item 98483887.

Kindlin-2 inhibits TNF/NF-κB-Caspase 8 pathway in hepatocytes to maintain liver development and function

Huanqing Gao, Yiming Zhong, Liang Zhou, Sixiong Lin, Xiaoting Hou, Zhen Ding, Yan Li, Qing Yao, Huiling Cao, Xuenong Zou, Di Chen, Xiaochun Bai, Guozhi Xiao

eLife. 2023; 12: e81792. Published online 2023 Jan 9. doi: 10.7554/eLife.81792

PMCID:: PMC9848388

Abstract Article PDF–11M

Select item 95683848.

Kindlin-2通过mTOR和Hippo信号通路调节小鼠子宫内膜发育

张京, 宋佳桂, 王振斌, 龚玉清, 王天卓, 周津羽, 战军, 张宏权

Beijing Da Xue Xue Bao Yi Xue Ban. 2022 Oct 18; 54(5): 846–852. Chinese. Published online 2022 Aug 30. doi: 10.19723/j.issn.1671-167X.2022.05.012

PMCID:: PMC9568384

Abstract Article PDF–5.0M

Select item 92533139.

Kindlin-2 loss in condylar chondrocytes causes spontaneous osteoarthritic lesions in the temporomandibular joint in mice

Yumei Lai, Wei Zheng, Minghao Qu, Christopher C. Xiao, Sheng Chen, Qing Yao, Weiyuan Gong, Chu Tao, Qinnan Yan, Peijun Zhang, Xiaohao Wu, Guozhi Xiao

Int J Oral Sci. 2022; 14: 33. Published online 2022 Jul 4. doi: 10.1038/s41368-022-00185-1

PMCID:: PMC9253313

Abstract Article PDF–7.7M

Select item 912295110.

Kindlin-2 promotes Src-mediated tyrosine phosphorylation of androgen receptor and contributes to breast cancer progression

Luyao Ma, Yeteng Tian, Tao Qian, Wenjun Li, Chengmin Liu, Bizhu Chu, Qian Kong, Renwei Cai, Panzhu Bai, Lisha Ma, Yi Deng, Ruijun Tian, Chuanyue Wu, Ying Sun

Cell Death Dis. 2022 May; 13(5): 482. Published online 2022 May 20. doi: 10.1038/s41419-022-04945-z

PMCID:: PMC9122951

Abstract Article PDF–6.2M

Select item 880662611.

Fermitin family homolog 2 (Kindlin-2) affects vascularization during the wound healing process by regulating the Wnt/β-catenin signaling pathway in vascular endothelial cells

Jianghui Ying, Qiang Wang, Lu Lu, Jiaqi Liu, Rong Guo, Hao Hu, Hua Jiang, Fazhi Qi

Bioengineered. 2021; 12(1): 4654–4665. Published online 2021 Aug 2. doi: 10.1080/21655979.2021.1957526

PMCID:: PMC8806626

Abstract Article PDF–3.2M

Select item 874879812.

Kindlin-2 inhibits Nlrp3 inflammasome activation in nucleus pulposus to maintain homeostasis of the intervertebral disc

Sheng Chen, Xiaohao Wu, Yumei Lai, Di Chen, Xiaochun Bai, Sheng Liu, Yongchao Wu, Mingjue Chen, Yuxiao Lai, Huiling Cao, Zengwu Shao, Guozhi Xiao

Bone Res. 2022; 10: 5. Published online 2022 Jan 10. doi: 10.1038/s41413-021-00179-5

PMCID:: PMC8748798

Abstract Article PDF–7.7M

Select item 831323913.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 819601414.

Kindlin-2 in Sertoli cells is essential for testis development and male fertility in mice

Xiaochun Chi, Weiwei Luo, Jiagui Song, Bing Li, Tiantian Su, Miao Yu, Tianzhuo Wang, Zhenbin Wang, Cheng Liu, Zhen Li, Huiying He, Jun Zhan, Hongquan Zhang

Cell Death Dis. 2021 Jun; 12(6): 604. Published online 2021 Jun 11. doi: 10.1038/s41419-021-03885-4

PMCID:: PMC8196014

Abstract Article PDF–11M

Select item 799467115.

Kindlin-2 mediates mechanotransduction in bone by regulating expression of Sclerostin in osteocytes

Lei Qin, Xuekun Fu, Jing Ma, Manxia Lin, Peijun Zhang, Yishu Wang, Qinnan Yan, Chu Tao, Wen Liu, Bin Tang, Di Chen, Xiaochun Bai, Huiling Cao, Guozhi Xiao

Commun Biol. 2021; 4: 402. Published online 2021 Mar 25. doi: 10.1038/s42003-021-01950-4

PMCID:: PMC7994671

Abstract Article PDF–7.5M

Select item 793877016.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 780895617.

Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis

Francisco Javier Ruiz-Ojeda, Jiefu Wang, Theresa Bäcker, Martin Krueger, Samira Zamani, Simon Rosowski, Tim Gruber, Yasuhiro Onogi, Annette Feuchtinger, Tim J. Schulz, Reinhard Fässler, Timo D. Müller, Cristina García-Cáceres, Matthias Meier, Matthias Blüher, Siegfried Ussar

Mol Metab. 2021 Mar; 45: 101147. Published online 2021 Jan 7. doi: 10.1016/j.molmet.2020.101147

PMCID:: PMC7808956

Abstract Article PDF–4.8M

Select item 776275318.

Kindlin-2 regulates skeletal homeostasis by modulating PTH1R in mice

Xuekun Fu, Bo Zhou, Qinnan Yan, Chu Tao, Lei Qin, Xiaohao Wu, Sixiong Lin, Sheng Chen, Yumei Lai, Xuenong Zou, Zengwu Shao, Meiqing Wang, Di Chen, Wenfei Jin, Youqiang Song, Huiling Cao, Ge Zhang, Guozhi Xiao

Signal Transduct Target Ther. 2020; 5: 297. Published online 2020 Dec 26. doi: 10.1038/s41392-020-00328-y

PMCID:: PMC7762753

Abstract Article PDF–7.1M

Select item 770150319.

Involvement of kindlin‐2 in irisin’s protection against ischaemia reperfusion‐induced liver injury in high‐fat diet‐fed mice

Jia Zhang, Yifan Ren, Jianbin Bi, Mengzhou Wang, Lin Zhang, Tao Wang, Shasha Wei, Xingyi Mou, Yi Lv, Rongqian Wu

J Cell Mol Med. 2020 Nov; 24(22): 13081–13092. Published online 2020 Sep 20. doi: 10.1111/jcmm.15910

PMCID:: PMC7701503

Abstract Article PDF–2.6M

Select item 732615420.

Effects of Kindlin-2 on proliferation and migration of VSMC and integrinβ1 andβ3 activity via FAK-PI3K signaling pathway

Xiaolin Wu, Fang Bian, He Hu, Tongjian Zhu, Chenyu Li, Qing Zhou

PLoS One. 2020; 15(6): e0225173. Published online 2020 Jun 30. doi: 10.1371/journal.pone.0225173

PMCID:: PMC7326154

Abstract Article PDF–2.6M

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