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Select item 103661641.

Cationic-nanogel nasal vaccine containing the ectodomain of RSV-small hydrophobic protein induces protective immunity in rodents

Shingo Umemoto, Rika Nakahashi-Ouchida, Yoshikazu Yuki, Shiho Kurokawa, Tomonori Machita, Yohei Uchida, Hiromi Mori, Tomoyuki Yamanoue, Takehiko Shibata, Shin-ichi Sawada, Kazuya Ishige, Takashi Hirano, Kohtaro Fujihashi, Kazunari Akiyoshi, Yosuke Kurashima, Daisuke Tokuhara, Peter B Ernst, Masashi Suzuki, Hiroshi Kiyono

NPJ Vaccines. 2023; 8: 106. Published online 2023 Jul 24. doi: 10.1038/s41541-023-00700-3

PMCID:: PMC10366164

Abstract Article PDF–2.7M

Select item 102626942.

M cell maturation and cDC activation determine the onset of adaptive immune priming in the neonatal Peyer’s patch

Natalia Torow, Ronghui Li, Thomas Charles Adrian Hitch, Clemens Mingels, Shahed Al Bounny, Niels van Best, Eva-Lena Stange, Britta Simons, Tiago Maié, Lennart Rüttger, Narasimha Murthy Keshava Prasad Gubbi, Darryl Adelaide Abbott, Adam Benabid, Michael Gadermayr, Solveig Runge, Nicole Treichel, Dorit Merhof, Stephan Patrick Rosshart, Nico Jehmlich, Timothy Wesley Hand, Martin von Bergen, Felix Heymann, Oliver Pabst, Thomas Clavel, Frank Tacke, Hugues Lelouard, Ivan Gesteira Costa, Mathias Walter Hornef

Immunity. 2023 Jun 13; 56(6): 1220–1238.e7. doi: 10.1016/j.immuni.2023.04.002

PMCID:: PMC10262694

Abstract Article

Select item 98842413.

Polymeric immunoglobulin receptor deficiency exacerbates autoimmune hepatitis by inducing intestinal dysbiosis and barrier dysfunction

Hongwei Lin, Jing Lin, Tongtong Pan, Ting Li, Huimian Jiang, Yan Fang, Yuxin Wang, Faling Wu, Jia Huang, Huadong Zhang, Dazhi Chen, Yongping Chen

Cell Death Dis. 2023 Jan; 14(1): 68. Published online 2023 Jan 28. doi: 10.1038/s41419-023-05589-3

Correction in:: Cell Death Dis. 2023 May; 14(5): 300.

PMCID:: PMC9884241

Abstract Article PDF–8.8M

Select item 90439584.

EpCAM Is Essential to Maintaining the Immune Homeostasis of Intestines via Keeping the Expression of pIgR in the Intestinal Epithelium of Mice

Zili Lei, Wanwan Liu, Ya Nie, Yanhong Yang, Guibin Chen, Li Huang, Huijuan Wu, Yuting Lei, Lei Chen, Qing Hu, Hedong Rong, Siping Yu, Qi Song, Fengxue Tong, Jiao Guo

Front Immunol. 2022; 13: 843378. Published online 2022 Apr 13. doi: 10.3389/fimmu.2022.843378

PMCID:: PMC9043958

Abstract Article PDF–8.1M

Select item 88812725.

Exogenous and Endogenous Triggers Differentially Stimulate Pigr Expression and Antibacterial Secretory Immunity in the Murine Respiratory Tract

Alexander Pausder, Jennifer Fricke, Klaus Schughart, Jens Schreiber, Till Strowig, Dunja Bruder, Julia D. Boehme

Lung. 2022; 200(1): 119–128. Published online 2021 Nov 26. doi: 10.1007/s00408-021-00498-8

PMCID:: PMC8881272

Abstract Article PDF–1.1M

Select item 73150456.

Respiratory Immunization With a Whole Cell Inactivated Vaccine Induces Functional Mucosal Immunoglobulins Against Tuberculosis in Mice and Non-human Primates

Nacho Aguilo, Santiago Uranga, Elena Mata, Raquel Tarancon, Ana Belén Gómez, Dessislava Marinova, Isabel Otal, Marta Monzón, Juan Badiola, Dolores Montenegro, Eugenia Puentes, Esteban Rodríguez, Richard A. W. Vervenne, Claudia C. Sombroek, Frank A. W. Verreck, Carlos Martín

Front Microbiol. 2020; 11: 1339. Published online 2020 Jun 18. doi: 10.3389/fmicb.2020.01339

PMCID:: PMC7315045

Abstract Article PDF–2.6M

Select item 66379677.

Epithelial endoplasmic reticulum stress orchestrates a protective IgA response

Joep Grootjans, Niklas Krupka, Shuhei Hosomi, Juan D. Matute, Thomas Hanley, Svetlana Saveljeva, Thomas Gensollen, Jarom Heijmans, Hai Li, Julien P. Limenitakis, Stephanie C. Ganal-Vonarburg, Shengbao Suo, Adrienne M. Luoma, Yosuke Shimodaira, Jinzhi Duan, David Q. Shih, Margaret E. Conner, Jonathan N. Glickman, Gwenny M. Fuhler, Noah W. Palm, Marcel R. de Zoete, C. Janneke van der Woude, Guo-Cheng Yuan, Kai W. Wucherpfennig, Stephan R. Targan, Philip Rosenstiel, Richard A. Flavell, Kathy D. McCoy, Andrew J. Macpherson, Arthur Kaser, Richard S. Blumberg

Science. Author manuscript; available in PMC 2019 Jul 18.

Published in final edited form as: Science. 2019 Mar 1; 363(6430): 993–998. doi: 10.1126/science.aat7186

PMCID:: PMC6637967

Abstract Article PDF–971K

Select item 63757408.

Maternal immunization confers protection to the offspring against an attaching and effacing pathogen through delivery of IgG in breast milk

Gustavo Caballero-Flores, Kei Sakamoto, Melody Zeng, Yaqiu Wang, Jill Hakim, Violeta Matus-Acuña, Naohiro Inohara, Gabriel Núñez

Cell Host Microbe. Author manuscript; available in PMC 2020 Feb 13.

Published in final edited form as: Cell Host Microbe. 2019 Feb 13; 25(2): 313–323.e4. Published online 2019 Jan 24. doi: 10.1016/j.chom.2018.12.015

PMCID:: PMC6375740

Abstract Article PDF–2.2M

Select item 62324729.

Natural Secretory Immunoglobulins Promote Enteric Viral Infections

Holly Turula, Juliana Bragazzi Cunha, Bernardo A. Mainou, Sadeesh K. Ramakrishnan, Carol A. Wilke, Mariam B. Gonzalez-Hernandez, Alexandra Pry, Julianne Fava, Christine M. Bassis, Jacob Edelman, Yatrik M. Shah, Blaise Corthesy, Bethany B. Moore, Christiane E. Wobus

J Virol. 2018 Dec 1; 92(23): e00826-18. Prepublished online 2018 Sep 19. Published online 2018 Nov 12. doi: 10.1128/JVI.00826-18

PMCID:: PMC6232472

Abstract Article PDF–3.4M

Select item 605096310.

Acinetobacter baumannii Gastrointestinal Colonization Is Facilitated by Secretory IgA Which Is Reductively Dissociated by Bacterial Thioredoxin A

Patrick M. Ketter, Jieh-Juen Yu, M. Neal Guentzel, Holly C. May, Rishein Gupta, Mark Eppinger, Karl E. Klose, J. Seshu, James P. Chambers, Andrew P. Cap, Bernard P. Arulanandam

mBio. 2018 Jul-Aug; 9(4): e01298-18. Published online 2018 Jul 10. doi: 10.1128/mBio.01298-18

PMCID:: PMC6050963

Abstract Article PDF–1.9M

Select item 600266211.

Bacterial-derived Neutrophilic Inflammation Drives Lung Remodeling in a Mouse Model of Chronic Obstructive Pulmonary Disease

Bradley W. Richmond, Rui-Hong Du, Wei Han, John T. Benjamin, Riet van der Meer, Linda Gleaves, Marshall Guo, Austin McKissack, Yongqin Zhang, Dong-Sheng Cheng, Vasiliy V. Polosukhin, Timothy S. Blackwell

Am J Respir Cell Mol Biol. 2018 Jun; 58(6): 736–744. doi: 10.1165/rcmb.2017-0329OC

PMCID:: PMC6002662

Abstract Article PDF–1.8M

Select item 598357012.

Enhanced survival following oral and systemic Salmonella enterica serovar Typhimurium infection in polymeric immunoglobulin receptor knockout mice

Kristina J. Betz, Elizabeth A. Maier, Surya Amarachintha, David Wu, Erik P. Karmele, Jeremy M. Kinder, Kris A. Steinbrecher, Monica M. McNeal, Deborah H. Luzader, Simon P. Hogan, Sean R. Moore

PLoS One. 2018; 13(6): e0198434. Published online 2018 Jun 1. doi: 10.1371/journal.pone.0198434

PMCID:: PMC5983570

Abstract Article PDF–1.8M

Select item 588444913.

Inflammation-induced IgA⁺ cells dismantle anti-liver cancer immunity

Shabnam Shalapour, Xue-Jia Lin, Ingmar N. Bastian, John Brain, Alastair D. Burt, Alexander A. Aksenov, Alison F. Vrbanac, Weihua Li, Andres Perkins, Takaji Matsutani, Zhenyu Zhong, Debanjan Dhar, Jose A. Navas-Molina, Jun Xu, Rohit Loomba, Michael Downes, Ruth T. Yu, Ronald M. Evans, Pieter C. Dorrestein, Rob Knight, Christopher Benner, Quentin M. Anstee, Michael Karin

Nature. Author manuscript; available in PMC 2018 May 16.

Published in final edited form as: Nature. 2017 Nov 16; 551(7680): 340–345. Published online 2017 Nov 8. doi: 10.1038/nature24302

Correction in:: Nature. 2017 Dec 21; 552(7685): 430.

Correction in:: Nature. 2018 Sep; 561(7721): E1.

PMCID:: PMC5884449

Abstract Article PDF–5.3M

Select item 546100214.

pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion

Federico Iovino, Joo-Yeon Engelen-Lee, Matthijs Brouwer, Diederik van de Beek, Arie van der Ende, Merche Valls Seron, Peter Mellroth, Sandra Muschiol, Jan Bergstrand, Jerker Widengren, Birgitta Henriques-Normark

J Exp Med. 2017 Jun 5; 214(6): 1619–1630. doi: 10.1084/jem.20161668

PMCID:: PMC5461002

Abstract Article PDF–1.4M

Select item 538122615.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 482207316.

Airway bacteria drive a progressive COPD-like phenotype in mice with polymeric immunoglobulin receptor deficiency

Bradley W. Richmond, Robert M. Brucker, Wei Han, Rui-Hong Du, Yongqin Zhang, Dong-Sheng Cheng, Linda Gleaves, Rasul Abdolrasulnia, Dina Polosukhina, Peter E. Clark, Seth R. Bordenstein, Timothy S. Blackwell, Vasiliy V. Polosukhin

Nat Commun. 2016; 7: 11240. Published online 2016 Apr 5. doi: 10.1038/ncomms11240

PMCID:: PMC4822073

Abstract Article PDF–2.1M

Select item 455250117.

Enhanced differentiation of intraepithelial lymphocytes in the intestine of polymeric immunoglobulin receptor-deficient mice

Noriko Kato-Nagaoka, Shin-Ichiro Shimada, Yoko Yamakawa, Satoshi Tsujibe, Tomoaki Naito, Hiromi Setoyama, Yohei Watanabe, Kan Shida, Satoshi Matsumoto, Masanobu Nanno

Immunology. 2015 Sep; 146(1): 59–69. Published online 2015 Jun 26. doi: 10.1111/imm.12480

PMCID:: PMC4552501

Abstract Article PDF–448K

Select item 450547818.

Exploitation of the Polymeric Immunoglobulin Receptor for Antibody Targeting to Renal Cyst Lumens in Polycystic Kidney Disease

Erin E. Olsan, Tamami Matsushita, Mina Rezaei, Thomas Weimbs

J Biol Chem. 2015 Jun 19; 290(25): 15679–15686. Published online 2015 Apr 28. doi: 10.1074/jbc.M114.607929

PMCID:: PMC4505478

Abstract Article PDF–1.6M

Select item 442564319.

Vertically transmitted fecal IgA levels distinguish extra-chromosomal phenotypic variation

Clara Moon, Megan T. Baldridge, Meghan A. Wallace, Carey-Ann D, Burnham, Herbert W. Virgin, Thaddeus S. Stappenbeck

Nature. Author manuscript; available in PMC 2015 Nov 7.

Published in final edited form as: Nature. 2015 May 7; 521(7550): 90–93. Published online 2015 Feb 16. doi: 10.1038/nature14139

PMCID:: PMC4425643

Abstract Article PDF–2.4M

Select item 440429720.

Phenotypic Analysis of a Population of IgA⁺ Cells in the Follicle-Associated Epithelium of Mouse Peyer's Patches

Maria Olga Hernandez, Nicholas J. Mantis

PLoS One. 2015; 10(4): e0124111. Published online 2015 Apr 20. doi: 10.1371/journal.pone.0124111

PMCID:: PMC4404297

Abstract Article PDF–2.0M

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