U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO Profiles

Items: 1 to 20 of 87

1.
Combined effects of prostaglandin E receptor subtype EP1 and subtype EP4 antagonists on intestinal tumorigenesis in adenomatous polyposis coli gene knockout mice
Tomohiro Kitamura, Masaki Itoh, Tetsuo Noda, Kousuke Tani, Michiyoshi Kobayashi, Takayuki Maruyama, Kaoru Kobayashi, Shuichi Ohuchida, Takashi Sugimura, Keiji Wakabayashi
Cancer Sci. 2003 Jul; 94(7): 618–621. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2003.tb01492.x
PMCID:
PMC11160211
AbstractArticlePDF–112K
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
PKN1 Exerts Neurodegenerative Effects in an In Vitro Model of Cerebellar Hypoxic–Ischemic Encephalopathy via Inhibition of AKT/GSK3β Signaling
Stephanie zur Nedden, Motahareh Solina Safari, Friedrich Fresser, Klaus Faserl, Herbert Lindner, Bettina Sarg, Gottfried Baier, Gabriele Baier-Bitterlich
Biomolecules. 2023 Nov; 13(11): 1599. Published online 2023 Oct 31. doi: 10.3390/biom13111599
PMCID:
PMC10669522
AbstractArticlePDF–3.5M
4.
EP1 activation inhibits doxorubicin-cardiomyocyte ferroptosis via Nrf2
Bei Wang, Yuxuan Jin, Jiao Liu, Qian Liu, Yujun Shen, Shengkai Zuo, Ying Yu
Redox Biol. 2023 Sep; 65: 102825. Published online 2023 Jul 24. doi: 10.1016/j.redox.2023.102825
PMCID:
PMC10400469
AbstractArticlePDF–12M
5.
Phosphorylation of KRT8 (keratin 8) by excessive mechanical load-activated PKN (protein kinase N) impairs autophagosome initiation and contributes to disc degeneration
Di Wang, Qiliang Shang, Jianxin Mao, Chu Gao, Jie Wang, Dong Wang, Han Wang, Haoruo Jia, Pandi Peng, Mu Du, Zhuojing Luo, Liu Yang
Autophagy. 2023; 19(9): 2485–2503. Published online 2023 Mar 10. doi: 10.1080/15548627.2023.2186099
PMCID:
PMC10392755
AbstractArticlePDF–9.5M
6.
PKN2 deficiency leads both to prenatal ‘congenital’ cardiomyopathy and defective angiotensin II stress responses
Jacqueline J.T. Marshall, Joshua J. Cull, Hajed O. Alharbi, May Zaw Thin, Susanna T.E. Cooper, Christopher Barrington, Hannah Vanyai, Thomas Snoeks, Bernard Siow, Alejandro Suáarez-Bonnet, Eleanor Herbert, Daniel J. Stuckey, Angus J.M. Cameron, Fabrice Prin, Andrew C. Cook, Simon L. Priestnall, Sonia Chotani, Owen J. L. Rackham, Daniel N. Meijles, Tim Mohun, Angela Clerk, Peter J. Parker
Biochem J. 2022 Jul 15; 479(13): 1467–1486. Prepublished online 2022 Jun 22. Published online 2022 Jul 12. doi: 10.1042/BCJ20220281
PMCID:
PMC9342899
AbstractArticlePDF–30M
7.
Protein kinase N2 mediates flow-induced endothelial NOS activation and vascular tone regulation
Young-June Jin, Ramesh Chennupati, Rui Li, Guozheng Liang, ShengPeng Wang, András Iring, Johannes Graumann, Nina Wettschureck, Stefan Offermanns
J Clin Invest. 2021 Nov 1; 131(21): e145734. Published online 2021 Nov 1. doi: 10.1172/JCI145734
PMCID:
PMC8553558
AbstractArticlePDF–7.7M
8.
Fever During Localized Inflammation in Mice Is Elicited by a Humoral Pathway and Depends on Brain Endothelial Interleukin-1 and Interleukin-6 Signaling and Central EP3 Receptors
Anna Eskilsson, Kiseko Shionoya, David Engblom, Anders Blomqvist
J Neurosci. 2021 Jun 16; 41(24): 5206–5218. doi: 10.1523/JNEUROSCI.0313-21.2021
PMCID:
PMC8211540
AbstractArticlePDF–5.4M
9.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
10.
PKN1 promotes synapse maturation by inhibiting mGluR-dependent silencing through neuronal glutamate transporter activation
Hiroki Yasuda, Hikaru Yamamoto, Kenji Hanamura, Mona Mehruba, Toshio Kawamata, Hiromi Morisaki, Masaaki Miyamoto, Shinji Takada, Tomoaki Shirao, Yoshitaka Ono, Hideyuki Mukai
Commun Biol. 2020; 3: 710. Published online 2020 Nov 26. doi: 10.1038/s42003-020-01435-w
PMCID:
PMC7691520
AbstractArticlePDF–3.4M
11.
Mechanistic definition of the cardiovascular mPGES-1/COX-2/ADMA axis
Nicholas S Kirkby, Joan Raouf, Blerina Ahmetaj-Shala, Bin Liu, Sarah I Mazi, Matthew L Edin, Mark Geoffrey Chambers, Marina Korotkova, Xiaomeng Wang, Walter Wahli, Darryl C Zeldin, Rolf Nüsing, Yingbi Zhou, Per-Johan Jakobsson, Jane A Mitchell
Cardiovasc Res. 2020 Oct 1; 116(12): 1972–1980. Published online 2019 Nov 5. doi: 10.1093/cvr/cvz290
PMCID:
PMC7519887
AbstractArticlePDF–928K
12.
Novel roles of PRK1 and PRK2 in cilia and cancer biology
Hitesh Patel, Jun Li, Ana Herrero, Jakob Kroboth, Adam Byron, Alex Von Kriegsheim, Valerie Brunton, Neil Carragher, Toby Hurd, Margaret Frame
Sci Rep. 2020; 10: 3902. Published online 2020 Mar 3. doi: 10.1038/s41598-020-60604-3
PMCID:
PMC7054267
AbstractArticlePDF–3.2M
13.
Inhibition of the Prostaglandin EP-1 Receptor in Periosteum Progenitor Cells Enhances Osteoblast Differentiation and Fracture Repair
Marina Feigenson, Jennifer H. Jonason, Jie Shen, Alayna E. Loiselle, Hani A. Awad, Regis J. O’Keefe
Ann Biomed Eng. Author manuscript; available in PMC 2020 Oct 12.
Published before final editing as: Ann Biomed Eng. 2019 Apr 12 : 10.1007/s10439-019-02264-7. doi: 10.1007/s10439-019-02264-7 [Epub ahead of print]
PMCID:
PMC6790162
AbstractArticlePDF–1.7M
14.
PKN1 kinase-negative knock-in mice develop splenomegaly and leukopenia at advanced age without obvious autoimmune-like phenotypes
Salman Mahmud Siddique, Koji Kubouchi, Yuka Shinmichi, Nana Sawada, Reiko Sugiura, Yasushi Itoh, Shunsuke Uehara, Kanae Nishimura, Shunsuke Okamura, Hiroyuki Ohsaki, Shingo Kamoshida, Yusuke Yamashita, Shinobu Tamura, Takashi Sonoki, Hiroshi Matsuoka, Tomoo Itoh, Hideyuki Mukai
Sci Rep. 2019; 9: 13977. Published online 2019 Sep 27. doi: 10.1038/s41598-019-50419-2
PMCID:
PMC6764976
AbstractArticlePDF–4.0M
15.
Plasticity in the Glucagon Interactome Reveals Novel Proteins That Regulate Glucagon Secretion in α-TC1-6 Cells
Farzad Asadi, Savita Dhanvantari
Front Endocrinol (Lausanne) 2018; 9: 792. Published online 2019 Jan 18. doi: 10.3389/fendo.2018.00792
PMCID:
PMC6346685
AbstractArticlePDF–3.6M
16.
Contribution of prostanoid FP receptor and prostaglandins in transient inflammatory ocular hypertension
Reiko Yamagishi-Kimura, Megumi Honjo, Makoto Aihara
Sci Rep. 2018; 8: 11098. Published online 2018 Jul 23. doi: 10.1038/s41598-018-29273-1
PMCID:
PMC6056481
AbstractArticlePDF–1.3M
17.
Protein kinase N1 critically regulates cerebellar development and long-term function
Stephanie zur Nedden, Rafaela Eith, Christoph Schwarzer, Lucia Zanetti, Hartwig Seitter, Friedrich Fresser, Alexandra Koschak, Angus J.M. Cameron, Peter J. Parker, Gottfried Baier, Gabriele Baier-Bitterlich
J Clin Invest. 2018 May 1; 128(5): 2076–2088. Published online 2018 Apr 16. doi: 10.1172/JCI96165
PMCID:
PMC5919825
AbstractArticlePDF–11M
18.
Loss of Protein Kinase Novel 1 (PKN1) is associated with mild systolic and diastolic contractile dysfunction, increased phospholamban Thr17 phosphorylation, and exacerbated ischaemia-reperfusion injury
Asvi A Francois, Kofo Obasanjo-Blackshire, James E Clark, Andrii Boguslavskyi, Mark R Holt, Peter J Parker, Michael S Marber, Richard J Heads
Cardiovasc Res. 2018 Jan 1; 114(1): 138–157. Published online 2017 Oct 16. doi: 10.1093/cvr/cvx206
PMCID:
PMC5815577
AbstractArticlePDF–1.7M
19.
PGE2 Receptor Subtype 1 (EP1) Regulates Mesenchymal Stromal Cell Osteogenic Differentiation by Modulating Cellular Energy Metabolism
M Feigenson, RA Eliseev, JH Jonason, BN Mills, RJ O’Keefe
J Cell Biochem. Author manuscript; available in PMC 2018 Dec 1.
Published in final edited form as: J Cell Biochem. 2017 Dec; 118(12): 4383–4393. Published online 2017 May 31. doi: 10.1002/jcb.26092
PMCID:
PMC5774856
AbstractArticlePDF–2.4M
20.
Reactive astrocyte COX2-PGE2 production inhibits oligodendrocyte maturation in neonatal white matter injury
Lawrence R Shiow, Geraldine Favrais, Lucas Schirmer, Anne-Laure Schang, Sara Cipriani, Christian Andres, Jaclyn N Wright, Hiroko Nobuta, Bobbi Fleiss, Pierre Gressens, David H Rowitch
Glia. Author manuscript; available in PMC 2018 Dec 1.
Published in final edited form as: Glia. 2017 Dec; 65(12): 2024–2037. Published online 2017 Aug 30. doi: 10.1002/glia.23212
PMCID:
PMC5753598
AbstractArticlePDF–904K

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Literature > PubMed Central (PMC)
Support Center