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Select item 113827101.

An unusual Toll/MyD88-mediated Drosophila host defence against Talaromyces marneffei

Xiaoyue Wang, Qinglin Qu, Zi Li, Sha Lu, Dominique Ferrandon, Liyan Xi

Fly (Austin) 2024; 18(1): 2398300. Published online 2024 Sep 6. doi: 10.1080/19336934.2024.2398300

PMCID:: PMC11382710

Abstract Article PDF–2.2M

Select item 111221212.

Transcriptomic Insights into Host Metabolism and Immunity Changes after Parasitization by Leptopilina myrica

Junwei Zhang, Jieyu Shan, Wenqi Shi, Ting Feng, Yifeng Sheng, Zixuan Xu, Zhi Dong, Jianhua Huang, Jiani Chen

Insects. 2024 May; 15(5): 352. Published online 2024 May 14. doi: 10.3390/insects15050352

PMCID:: PMC11122121

Abstract Article PDF–2.4M

Select item 108077683.

The evolution of constitutively active humoral immune defenses in Drosophila populations under high parasite pressure

Shuyu Olivia Zhou, Ramesh Arunkumar, Amina Irfan, Shuai Dominique Ding, Alexandre B. Leitão, Francis M. Jiggins

PLoS Pathog. 2024 Jan; 20(1): e1011729. Published online 2024 Jan 11. doi: 10.1371/journal.ppat.1011729

PMCID:: PMC10807768

Abstract Article PDF–1.9M

Select item 107338564.

Activation of immune defences against parasitoid wasps does not underlie the cost of infection

Alexandre B. Leitão, Emma M. Geldman, Francis M. Jiggins

Front Immunol. 2023; 14: 1275923. Published online 2023 Dec 7. doi: 10.3389/fimmu.2023.1275923

PMCID:: PMC10733856

Abstract Article PDF–1.3M

Select item 104348975.

The genetic basis of variation in immune defense against Lysinibacillus fusiformis infection in Drosophila melanogaster

Brittny R. Smith, Kistie B. Patch, Anjali Gupta, Emma M. Knoles, Robert L. Unckless

PLoS Pathog. 2023 Aug; 19(8): e1010934. Published online 2023 Aug 7. doi: 10.1371/journal.ppat.1010934

PMCID:: PMC10434897

Abstract Article PDF–2.5M

Select item 104340046.

Mycobacterium abscessus Opsonization Allows an Escape from the Defensin Bactericidal Action in Drosophila

Hamadoun Touré, Nicolas Durand, Isabelle Guénal, Jean-Louis Herrmann, Fabienne Girard-Misguich, Sébastien Szuplewski

Microbiol Spectr. 2023 Jul-Aug; 11(4): e00777-23. Published online 2023 Jun 1. doi: 10.1128/spectrum.00777-23

PMCID:: PMC10434004

Abstract Article PDF–1.7M

Select item 102703517.

Damage sensing mediated by serine proteases Hayan and Persephone for Toll pathway activation in apoptosis-deficient flies

Shotaro Nakano, Soshiro Kashio, Kei Nishimura, Asuka Takeishi, Hina Kosakamoto, Fumiaki Obata, Erina Kuranaga, Takahiro Chihara, Yoshio Yamauchi, Toshiaki Isobe, Masayuki Miura

PLoS Genet. 2023 Jun; 19(6): e1010761. Published online 2023 Jun 15. doi: 10.1371/journal.pgen.1010761

PMCID:: PMC10270351

Abstract Article PDF–2.8M

Select item 101633248.

Antimicrobial peptides do not directly contribute to aging in Drosophila, but improve lifespan by preventing dysbiosis

Mark A. Hanson, Bruno Lemaitre

Dis Model Mech. 2023 Apr 1; 16(4): dmm049965. Published online 2023 Apr 26. doi: 10.1242/dmm.049965

PMCID:: PMC10163324

Abstract Article

Select item 101057369.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 1007922710.

Mycobacterium abscessus resists the innate cellular response by surviving cell lysis of infected phagocytes

Hamadoun Touré, Lee Ann Galindo, Marion Lagune, Simon Glatigny, Robert M. Waterhouse, Isabelle Guénal, Jean-Louis Herrmann, Fabienne Girard-Misguich, Sébastien Szuplewski

PLoS Pathog. 2023 Mar; 19(3): e1011257. Published online 2023 Mar 27. doi: 10.1371/journal.ppat.1011257

PMCID:: PMC10079227

Abstract Article PDF–2.1M

Select item 1004112611.

A Toll pathway effector protects Drosophila specifically from distinct toxins secreted by a fungus or a bacterium

Jianqiong Huang, Yanyan Lou, Jiyong Liu, Philippe Bulet, Chuping Cai, Kaiyu Ma, Renjie Jiao, Jules A. Hoffmann, Samuel Liégeois, Zi Li, Dominique Ferrandon

Proc Natl Acad Sci U S A. 2023 Mar 21; 120(12): e2205140120. Published online 2023 Mar 14. doi: 10.1073/pnas.2205140120

PMCID:: PMC10041126

Abstract Article PDF–848K

Select item 982754812.

The Toll pathway mediates Drosophila resilience to Aspergillus mycotoxins through specific Bomanins

Rui Xu, Yanyan Lou, Antonin Tidu, Philippe Bulet, Thorsten Heinekamp, Franck Martin, Axel Brakhage, Zi Li, Samuel Liégeois, Dominique Ferrandon

EMBO Rep. 2023 Jan; 24(1): e56036. Published online 2022 Nov 2. doi: 10.15252/embr.202256036

PMCID:: PMC9827548

Abstract Article PDF–3.4M

Select item 967144313.

Trans-regulatory changes underpin the evolution of the Drosophila immune response

Shuai Dominique Ding, Alexandre B. Leitão, Jonathan P. Day, Ramesh Arunkumar, Morgan Phillips, Shuyu Olivia Zhou, Francis M. Jiggins

PLoS Genet. 2022 Nov; 18(11): e1010453. Published online 2022 Nov 7. doi: 10.1371/journal.pgen.1010453

PMCID:: PMC9671443

Abstract Article PDF–2.2M

Select item 963564414.

Enteric bacterial infection in Drosophila induces whole-body alterations in metabolic gene expression independently of the immune deficiency signaling pathway

Rujuta Deshpande, Byoungchun Lee, Savraj S Grewal

G3 (Bethesda) 2022 Nov; 12(11): jkac163. Published online 2022 Jul 4. doi: 10.1093/g3journal/jkac163

PMCID:: PMC9635644

Abstract Article PDF–2.2M

Select item 958355315.

HP1a-mediated heterochromatin formation promotes antimicrobial responses against Pseudomonas aeruginosa infection

Po-Jen Wu, Shian-Jang Yan

BMC Biol. 2022; 20: 234. Published online 2022 Oct 20. doi: 10.1186/s12915-022-01435-8

PMCID:: PMC9583553

Abstract Article PDF–7.6M

Select item 920864816.

microRNA-252 and FoxO repress inflammaging by a dual inhibitory mechanism on Dawdle-mediated TGF-β pathway in Drosophila

Xiaofen Wu, Kongyan Niu, Xiaofan Wang, Jing Zhao, Han Wang, Dean Li, Hui Wang, Ting Miao, Yun Yang, Huanhuan Ma, Yaoyang Zhang, Lei Pan, Rui Liu, Hua Bai, Nan Liu

Genetics. 2022 Mar; 220(3): iyab234. Published online 2021 Dec 21. doi: 10.1093/genetics/iyab234