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Items: 1 to 20 of 46

1.
A neuron–glia lipid metabolic cycle couples daily sleep to mitochondrial homeostasis
Paula R. Haynes, Elana S. Pyfrom, Yongjun Li, Carly Stein, Vishnu Anand Cuddapah, Jack A. Jacobs, Zhifeng Yue, Amita Sehgal
Nat Neurosci. 2024; 27(4): 666–678. Published online 2024 Feb 15. doi: 10.1038/s41593-023-01568-1
PMCID:
PMC11001586
AbstractArticlePDF–5.6M
2.
Apolipoprotein D in Oxidative Stress and Inflammation
Guillaume Fyfe-Desmarais, Fréderik Desmarais, Éric Rassart, Catherine Mounier
Antioxidants (Basel) 2023 May; 12(5): 1027. Published online 2023 Apr 28. doi: 10.3390/antiox12051027
PMCID:
PMC10215970
AbstractArticlePDF–1.3M
3.
Glycolytically impaired Drosophila glial cells fuel neural metabolism via β-oxidation
Ellen McMullen, Helen Hertenstein, Katrin Strassburger, Leon Deharde, Marko Brankatschk, Stefanie Schirmeier
Nat Commun. 2023; 14: 2996. Published online 2023 May 24. doi: 10.1038/s41467-023-38813-x
PMCID:
PMC10209077
AbstractArticlePDF–1.1M
4.
‘Fly’ing from rare to common neurodegenerative disease mechanisms
Mengqi Ma, Matthew J. Moulton, Shenzhao Lu, Hugo J. Bellen
Trends Genet. Author manuscript; available in PMC 2023 Sep 1.
Published in final edited form as: Trends Genet. 2022 Sep; 38(9): 972–984. Published online 2022 Apr 25. doi: 10.1016/j.tig.2022.03.018
PMCID:
PMC9378361
AbstractArticlePDF–1.0M
5.
Neuronal activity induces glucosylceramide that is secreted via exosomes for lysosomal degradation in glia
Liping Wang, Guang Lin, Zhongyuan Zuo, Yarong Li, Seul Kee Byeon, Akhilesh Pandey, Hugo J. Bellen
Sci Adv. 2022 Jul; 8(28): eabn3326. Published online 2022 Jul 13. doi: 10.1126/sciadv.abn3326
PMCID:
PMC9278864
AbstractArticlePDF–9.4M
6.
Targeting metabolic pathways for extension of lifespan and healthspan across multiple species
Andrey A. Parkhitko, Elizabeth Filine, Stephanie E. Mohr, Alexey Moskalev, Norbert Perrimon
Ageing Res Rev. Author manuscript; available in PMC 2022 Apr 25.
Published in final edited form as: Ageing Res Rev. 2020 Dec; 64: 101188. Published online 2020 Oct 5. doi: 10.1016/j.arr.2020.101188
PMCID:
PMC9038119
AbstractArticlePDF–2.0M
7.
Neuronal ROS-induced glial lipid droplet formation is altered by loss of Alzheimer’s disease–associated genes
Matthew J. Moulton, Scott Barish, Isha Ralhan, Jinlan Chang, Lindsey D. Goodman, Jake G. Harland, Paul C. Marcogliese, Jan O. Johansson, Maria S. Ioannou, Hugo J. Bellen
Proc Natl Acad Sci U S A. 2021 Dec 28; 118(52): e2112095118. Published online 2021 Dec 23. doi: 10.1073/pnas.2112095118
PMCID:
PMC8719885
AbstractArticlePDF–2.8M
8.
Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes
Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis
G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349
PMCID:
PMC8664486
AbstractArticlePDF–3.1M
9.
Brain-specific lipoprotein receptors interact with astrocyte derived apolipoprotein and mediate neuron-glia lipid shuttling
Jun Yin, Emma Spillman, Ethan S. Cheng, Jacob Short, Yang Chen, Jingce Lei, Mary Gibbs, Justin S. Rosenthal, Chengyu Sheng, Yuki X. Chen, Kelly Veerasammy, Tenzin Choetso, Rinat Abzalimov, Bei Wang, Chun Han, Ye He, Quan Yuan
Nat Commun. 2021; 12: 2408. Published online 2021 Apr 23. doi: 10.1038/s41467-021-22751-7
PMCID:
PMC8065144
AbstractArticlePDF–14M
10.
Altered lipid metabolism in a Drosophila model of Friedreich's ataxia
Juan A. Navarro, Elisabeth Ohmann, Diego Sanchez, José A. Botella, Gerhard Liebisch, María D. Moltó, María D. Ganfornina, Gerd Schmitz, Stephan Schneuwly
Hum Mol Genet. 2010 Jul 15; 19(14): 2828–2840. Published online 2010 May 10. doi: 10.1093/hmg/ddq183
PMCID:
PMC7108586
AbstractArticlePDF–718K
11.
CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans
Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang
Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119
PMCID:
PMC6961578
AbstractArticlePDF–3.6M
12.
The role of lipid metabolism in aging, lifespan regulation, and age‐related disease
Adiv A. Johnson, Alexandra Stolzing
Aging Cell. 2019 Dec; 18(6): e13048. Published online 2019 Sep 27. doi: 10.1111/acel.13048
PMCID:
PMC6826135
AbstractArticlePDF–1.2M
13.
Impact of Drosophila Models in the Study and Treatment of Friedreich’s Ataxia
Véronique Monnier, Jose Vicente Llorens, Juan Antonio Navarro
Int J Mol Sci. 2018 Jul; 19(7): 1989. Published online 2018 Jul 7. doi: 10.3390/ijms19071989
PMCID:
PMC6073496
AbstractArticlePDF–2.3M
14.
Drosophila melanogaster Models of Friedreich's Ataxia
P. Calap-Quintana, J. A. Navarro, J. González-Fernández, M. J. Martínez-Sebastián, M. D. Moltó, J. V. Llorens
Biomed Res Int. 2018; 2018: 5065190. Published online 2018 Apr 5. doi: 10.1155/2018/5065190
PMCID:
PMC5907503
AbstractArticlePDF–1.7M
15.
Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species
Piero Sanfilippo, Jiayu Wen, Eric C. Lai
Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0
PMCID:
PMC5707805
AbstractArticlePDF–3.2M
16.
Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster
Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira
RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117
PMCID:
PMC5689002
AbstractArticlePDF–4.0M
17.
The glia-neuron lactate shuttle and elevated ROS promote lipid synthesis in neurons and lipid droplet accumulation in glia via APOE/D
Lucy Liu, Kevin R. MacKenzie, Nagireddy Putluri, Mirjana Maletić-Savatić, Hugo J. Bellen
Cell Metab. Author manuscript; available in PMC 2018 Nov 7.
Published in final edited form as: Cell Metab. 2017 Nov 7; 26(5): 719–737.e6. Published online 2017 Sep 28. doi: 10.1016/j.cmet.2017.08.024
PMCID:
PMC5677551
AbstractArticlePDF–2.7M
18.
Protecting cells by protecting their vulnerable lysosomes: Identification of a new mechanism for preserving lysosomal functional integrity upon oxidative stress
Raquel Pascua-Maestro, Sergio Diez-Hermano, Concepción Lillo, Maria D. Ganfornina, Diego Sanchez
PLoS Genet. 2017 Feb; 13(2): e1006603. Published online 2017 Feb 9. doi: 10.1371/journal.pgen.1006603
PMCID:
PMC5325589
AbstractArticlePDF–3.9M
19.
A genetic interaction map of cell cycle regulators
Maximilian Billmann, Thomas Horn, Bernd Fischer, Thomas Sandmann, Wolfgang Huber, Michael Boutros
Mol Biol Cell. 2016 Apr 15; 27(8): 1397–1407. doi: 10.1091/mbc.E15-07-0467
PMCID:
PMC4831891
AbstractArticlePDF–4.0M
20.
Gene expression profiling of brakeless mutant Drosophila embryos
Filip Crona, Bhumica Singla, Mattias Mannervik
Data Brief. 2015 Dec; 5: 134–137. Published online 2015 Sep 5. doi: 10.1016/j.dib.2015.08.033
PMCID:
PMC4579289
AbstractArticlePDF–284K

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