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Items: 1 to 20 of 346

1.
Autophagy impairment and lifespan reduction caused by Atg1 RNAi or Atg18 RNAi expression in adult fruit flies (Drosophila melanogaster)
Mariah Bierlein, Joseph Charles, Trevor Polisuk-Balfour, Heidi Bretscher, Micaela Rice, Jacklyn Zvonar, Drake Pohl, Lindsey Winslow, Brennah Wasie, Sara Deurloo, Jordan Van Wert, Britney Williams, Gabrielle Ankney, Zachary Harmon, Erica Dann, Anna Azuz, Alex Guzman-Vargas, Elizabeth Kuhns, Thomas P Neufeld, Michael B O’Connor, Felix Amissah, Changqi C Zhu
Genetics. 2023 Oct; 225(2): iyad154. Published online 2023 Aug 18. doi: 10.1093/genetics/iyad154
PMCID:
PMC11491525
AbstractArticlePDF–1.6M
2.
Drosophila medulla neuroblast termination via apoptosis, differentiation, and gliogenic switch is scheduled by the depletion of the neuroepithelial stem cell pool
Phuong-Khanh Nguyen, Louise Y Cheng
eLife. 2024; 13: e96876. Published online 2024 Jun 21. doi: 10.7554/eLife.96876
PMCID:
PMC11262793
AbstractArticlePDF–6.6M
3.
Drosophila Nhe2 overexpression induces autophagic cell death
Jobelle Peralta, Blake DuPriest, Daniel Orozco, Juan Reyna Pacheco, Laura Martins, Rachel Ann Soriano, Alan Wong, Ramy Wong, Bree Grillo-Hill
Mol Biol Cell. 2024 Jul 1; 35(7): br13. Published online 2024 Jul 1. doi: 10.1091/mbc.E24-02-0058
PMCID:
PMC11244158
AbstractArticlePDF–2.1M
4.
Endosome mediated nucleocytoplasmic trafficking and endomembrane allocation is crucial to polyglutamine toxicity
Yuyu Nan, Wenfeng Chen, Fei Chen, Lili Wei, Aiyuan Zeng, Xiaohui Lin, Wenbin Zhou, Yufeng Yang, Qinghua Li
Cell Biol Toxicol. 2024; 40(1): 48. Published online 2024 Jun 20. doi: 10.1007/s10565-024-09891-4
PMCID:
PMC11189978
AbstractArticlePDF–14M
5.
ESCRT disruption provides evidence against trans-synaptic signaling via extracellular vesicles
Erica C. Dresselhaus, Kathryn P. Harris, Cassandra R. Blanchette, Kate Koles, Steven J. Del Signore, Matthew F. Pescosolido, Biljana Ermanoska, Mark Rozencwaig, Rebecca C. Soslowsky, Michael J. Parisi, Bryan A. Stewart, Timothy J. Mosca, Avital A. Rodal
J Cell Biol. 2024 Sep 2; 223(9): e202405025. Published online 2024 Jun 6. doi: 10.1083/jcb.202405025
PMCID:
PMC11157088
AbstractArticlePDF–6.9M
6.
O-GlcNAc modification is essential for the regulation of autophagy in Drosophila melanogaster
Sujin Park, Yangsin Lee, Jin Won Pak, Hanbyeol Kim, Hyeonjin Choi, Jae-woo Kim, Jürgen Roth, Jin Won Cho
Cell Mol Life Sci. 2015 Aug; 72(16): 3173–3183. Published online 2015 Apr 4. doi: 10.1007/s00018-015-1889-z
PMCID:
PMC11114044
AbstractArticlePDF–3.6M
7.
Dysregulation of innate immune signaling in animal models of spinal muscular atrophy
Eric L. Garcia, Rebecca E. Steiner, Amanda C. Raimer, Laura E. Herring, A. Gregory Matera, Ashlyn M. Spring
BMC Biol. 2024; 22: 94. Published online 2024 Apr 25. doi: 10.1186/s12915-024-01888-z
PMCID:
PMC11044505
AbstractArticlePDF–4.0M
8.
Identification of secretory autophagy as a mechanism modulating activity-induced synaptic remodeling
Yen-Ching Chang, Yuan Gao, Joo Yeun Lee, Yi-Jheng Peng, Jennifer Langen, Karen T. Chang
Proc Natl Acad Sci U S A. 2024 Apr 16; 121(16): e2315958121. Published online 2024 Apr 8. doi: 10.1073/pnas.2315958121
PMCID:
PMC11032469
AbstractArticlePDF–3.8M
9.
Mitochondrial fusion and altered beta-oxidation drive muscle wasting in a Drosophila cachexia model
Callum Dark, Nashia Ali, Sofya Golenkina, Vaibhav Dhyani, Ronnie Blazev, Benjamin L Parker, Kate T Murphy, Gordon S Lynch, Tarosi Senapati, S Sean Millard, Sarah M Judge, Andrew R Judge, Lopamudra Giri, Sarah M Russell, Louise Y Cheng
EMBO Rep. 2024 Apr; 25(4): 1835–1858. Published online 2024 Mar 1. doi: 10.1038/s44319-024-00102-z
PMCID:
PMC11014992
AbstractArticlePDF–6.2M
10.
Elevated α-synuclein levels inhibit mitophagic flux
Inge Kinnart, Liselot Manders, Thibaut Heyninck, Dorien Imberechts, Roman Praschberger, Nils Schoovaerts, Catherine Verfaillie, Patrik Verstreken, Wim Vandenberghe
NPJ Parkinsons Dis. 2024; 10: 80. Published online 2024 Apr 9. doi: 10.1038/s41531-024-00696-0
PMCID:
PMC11004019
AbstractArticlePDF–6.7M
11.
Expanding the Drosophila toolkit for dual control of gene expression
Jonathan Zirin, Barbara Jusiak, Raphael Lopes, Benjamin Ewen-Campen, Justin A Bosch, Alexandria Risbeck, Corey Forman, Christians Villalta, Yanhui Hu, Norbert Perrimon
eLife. 2024; 12: RP94073. Published online 2024 Apr 3. doi: 10.7554/eLife.94073
PMCID:
PMC10990484
AbstractArticlePDF–6.0M
12.
Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila
Laura Vesala, Yuliya Basikhina, Tea Tuomela, Anssi Nurminen, Emilia Siukola, Pedro F. Vale, Tiina S. Salminen
BMC Biol. 2024; 22: 60. Published online 2024 Mar 13. doi: 10.1186/s12915-024-01858-5
PMCID:
PMC10935954
AbstractArticlePDF–2.4M
13.
Interplay between autophagy and CncC regulates dendrite pruning in Drosophila
Jue Yu Kelly Tan, Liang Yuh Chew, Gábor Juhász, Fengwei Yu
Proc Natl Acad Sci U S A. 2024 Mar 5; 121(10): e2310740121. Published online 2024 Feb 26. doi: 10.1073/pnas.2310740121
PMCID:
PMC10927499
AbstractArticlePDF–3.5M
14.
Understanding Developmental Cell Death Using Drosophila as a Model System
Ruchi Umargamwala, Jantina Manning, Loretta Dorstyn, Donna Denton, Sharad Kumar
Cells. 2024 Feb; 13(4): 347. Published online 2024 Feb 16. doi: 10.3390/cells13040347
PMCID:
PMC10886741
AbstractArticlePDF–1.6M
15.
The Drosophila ZNRF1/2 homologue, detour, interacts with HOPS complex and regulates autophagy
Shannon Nicolson, Jantina A. Manning, Yoon Lim, Xin Jiang, Erica Kolze, Sonia Dayan, Ruchi Umargamwala, Tianqi Xu, Jarrod J. Sandow, Andrew I. Webb, Sharad Kumar, Donna Denton
Commun Biol. 2024; 7: 183. Published online 2024 Feb 15. doi: 10.1038/s42003-024-05834-1
PMCID:
PMC10869362
AbstractArticlePDF–6.1M
16.
TDP-43 impairs sleep in Drosophila through Ataxin-2–dependent metabolic disturbance
Alexandra E. Perlegos, Jaclyn Durkin, Samuel J. Belfer, Anyara Rodriguez, Oksana Shcherbakova, Kristen Park, Jenny Luong, Nancy M. Bonini, Matthew S. Kayser
Sci Adv. 2024 Jan 12; 10(2): eadj4457. Published online 2024 Jan 10. doi: 10.1126/sciadv.adj4457
PMCID:
PMC10780954
AbstractArticlePDF–2.1M
17.
Atl (atlastin) regulates mTor signaling and autophagy in Drosophila muscle through alteration of the lysosomal network
Saurabh Srivastav, Kevin van der Graaf, Pratibha Singh, Alloysius Budi Utama, Matthew D. Meyer, James A. McNew, Michael Stern
Autophagy. 2024; 20(1): 131–150. Published online 2023 Aug 30. doi: 10.1080/15548627.2023.2249794
PMCID:
PMC10761077
AbstractArticlePDF–7.0M
18.
The Drosophila NPY-like system protects against chronic stress–induced learning deficit by preventing the disruption of autophagic flux
Tianli Chen, Mengyu Zhang, Zhaowen Ding, Jiao Hu, Jie Yang, Lei He, Jia Jia, Jingjing Yang, Junfei Yang, Xiaoxu Song, Peng Chen, Zongzhao Zhai, Jing Huang, Yirong Wang, Hongtao Qin
Proc Natl Acad Sci U S A. 2023 Dec 19; 120(51): e2307632120. Published online 2023 Dec 11. doi: 10.1073/pnas.2307632120
PMCID:
PMC10743384
AbstractArticlePDF–1.3M
19.
Microbes control Drosophila germline stem cell increase and egg maturation through hormonal pathways
Ritsuko Suyama, Nicolas Cetraro, Joanne Y. Yew, Toshie Kai
Commun Biol. 2023; 6: 1287. Published online 2023 Dec 20. doi: 10.1038/s42003-023-05660-x
PMCID:
PMC10733356
AbstractArticlePDF–3.7M
20.
A multi‐layered network model identifies Akt1 as a common modulator of neurodegeneration
Dokyun Na, Do‐Hwan Lim, Jae‐Sang Hong, Hyang‐Mi Lee, Daeahn Cho, Myeong‐Sang Yu, Bilal Shaker, Jun Ren, Bomi Lee, Jae Gwang Song, Yuna Oh, Kyungeun Lee, Kwang‐Seok Oh, Mi Young Lee, Min‐Seok Choi, Han Saem Choi, Yang‐Hee Kim, Jennifer M Bui, Kangseok Lee, Hyung Wook Kim, Young Sik Lee, Jörg Gsponer
Mol Syst Biol. 2023 Dec; 19(12): e11801. Published online 2023 Nov 20. doi: 10.15252/msb.202311801
PMCID:
PMC10698508
AbstractArticlePDF–7.0M

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