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Select item 111010781.

Glucose and trehalose metabolism through the cyclic pentose phosphate pathway shapes pathogen resistance and host protection in Drosophila

Michalina Kazek, Lenka Chodáková, Katharina Lehr, Lukáš Strych, Pavla Nedbalová, Ellen McMullen, Adam Bajgar, Stanislav Opekar, Petr Šimek, Martin Moos, Tomáš Doležal

PLoS Biol. 2024 May; 22(5): e3002299. Published online 2024 May 7. doi: 10.1371/journal.pbio.3002299

PMCID:: PMC11101078

Abstract Article PDF–3.9M

Select item 108510222.

Oxidative Stress Contributes to Slit Diaphragm Defects Caused by Disruption of Endocytosis

Gang Xi, Sajan A. Lamba, Michael Mysh, John S. Poulton

Kidney Int Rep. 2024 Feb; 9(2): 451–463. Published online 2023 Nov 25. doi: 10.1016/j.ekir.2023.11.018

PMCID:: PMC10851022

Abstract Article PDF–3.2M

Select item 107306623.

How to eliminate pathogen without killing oneself? Immunometabolism of encapsulation and melanization in Drosophila

Tomas Dolezal

Front Immunol. 2023; 14: 1330312. Published online 2023 Dec 6. doi: 10.3389/fimmu.2023.1330312

PMCID:: PMC10730662

Abstract Article PDF–1.7M

Select item 107281504.

Functional-metabolic coupling in distinct renal cell types coordinates organ-wide physiology and delays premature ageing

Jack Holcombe, Helen Weavers

Nat Commun. 2023; 14: 8405. Published online 2023 Dec 18. doi: 10.1038/s41467-023-44098-x

PMCID:: PMC10728150

Abstract Article PDF–14M

Select item 97331305.

Discovery and Visualization of Age-Dependent Patterns in the Diurnal Transcriptome of Drosophila

Benjamin Sebastian, Rosalyn M. Fey, Patrick Morar, Brittany Lasher, Jadwiga M. Giebultowicz, David A. Hendrix

J Circadian Rhythms. 2022; 20: 1. Published online 2022 Dec 8. doi: 10.5334/jcr.218

PMCID:: PMC9733130

Abstract Article PDF–9.0M

Select item 96356446.

Enteric bacterial infection in Drosophila induces whole-body alterations in metabolic gene expression independently of the immune deficiency signaling pathway

Rujuta Deshpande, Byoungchun Lee, Savraj S Grewal

G3 (Bethesda) 2022 Nov; 12(11): jkac163. Published online 2022 Jul 4. doi: 10.1093/g3journal/jkac163

PMCID:: PMC9635644

Abstract Article PDF–2.2M

Select item 93573197.

dGLYAT modulates Gadd45-mediated JNK activation and cell invasion

Meng Xu, Pu Ren, Juhui Tian, Lisha Xiao, Ping Hu, Ping Chen, Wenzhe Li, Lei Xue

Cell Div. 2022; 17: 4. Published online 2022 Aug 6. doi: 10.1186/s13008-022-00080-5

PMCID:: PMC9357319

Abstract Article PDF–6.8M

Select item 92738688.

Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics – An AI-Enabled Biological Target Discovery Platform

Frank W. Pun, Bonnie Hei Man Liu, Xi Long, Hoi Wing Leung, Geoffrey Ho Duen Leung, Quinlan T. Mewborne, Junli Gao, Anastasia Shneyderman, Ivan V. Ozerov, Ju Wang, Feng Ren, Alexander Aliper, Evelyne Bischof, Evgeny Izumchenko, Xiaoming Guan, Ke Zhang, Bai Lu, Jeffrey D. Rothstein, Merit E. Cudkowicz, Alex Zhavoronkov

Front Aging Neurosci. 2022; 14: 914017. Published online 2022 Jun 28. doi: 10.3389/fnagi.2022.914017

PMCID:: PMC9273868

Abstract Article PDF–3.6M

Select item 90853639.

Dietary Sucrose Determines Stress Resistance, Oxidative Damages, and Antioxidant Defense System in Drosophila

Olha Strilbytska, Tetiana Strutynska, Uliana Semaniuk, Nadia Burdyliyk, Volodymyr Bubalo, Oleh Lushchak

Scientifica (Cairo) 2022; 2022: 7262342. Published online 2022 May 2. doi: 10.1155/2022/7262342

PMCID:: PMC9085363

Abstract Article PDF–775K

Select item 903811910.

Targeting metabolic pathways for extension of lifespan and healthspan across multiple species

Andrey A. Parkhitko, Elizabeth Filine, Stephanie E. Mohr, Alexey Moskalev, Norbert Perrimon

Ageing Res Rev. Author manuscript; available in PMC 2022 Apr 25.

Published in final edited form as: Ageing Res Rev. 2020 Dec; 64: 101188. Published online 2020 Oct 5. doi: 10.1016/j.arr.2020.101188

PMCID:: PMC9038119

Abstract Article PDF–2.0M

Select item 896152811.

Phenotyping of Drosophila Melanogaster—A Nutritional Perspective

Virginia Eickelberg, Kai Lüersen, Stefanie Staats, Gerald Rimbach

Biomolecules. 2022 Feb; 12(2): 221. Published online 2022 Jan 27. doi: 10.3390/biom12020221

PMCID:: PMC8961528

Abstract Article PDF–7.8M

Select item 877410612.

Sexual Dimorphism in Metabolic Responses to Western Diet in Drosophila melanogaster

Sofie De Groef, Tom Wilms, Séverine Balmand, Federica Calevro, Patrick Callaerts

Biomolecules. 2022 Jan; 12(1): 33. Published online 2021 Dec 27. doi: 10.3390/biom12010033

PMCID:: PMC8774106

Abstract Article PDF–1.9M

Select item 864520713.

In vivo proximity biotin ligation identifies the interactome of Egalitarian, a Dynein cargo adaptor

Frederick C. Baker, Hannah Neiswender, Rajalakshmi Veeranan-Karmegam, Graydon B. Gonsalvez

Development. 2021 Nov 15; 148(22): dev199935. Published online 2021 Nov 18. doi: 10.1242/dev.199935

PMCID:: PMC8645207

Abstract Article

Select item 861049314.

Paths and pathways that generate cell-type heterogeneity and developmental progression in hematopoiesis

Juliet R Girard, Lauren M Goins, Dung M Vuu, Mark S Sharpley, Carrie M Spratford, Shreya R Mantri, Utpal Banerjee

eLife. 2021; 10: e67516. Published online 2021 Oct 29. doi: 10.7554/eLife.67516

PMCID:: PMC8610493

Abstract Article PDF–13M

Select item 846206515.

Heritable shifts in redox metabolites during mitochondrial quiescence reprogram progeny metabolism

Helin Hocaoglu, Lei Wang, Mengye Yang, Sibiao Yue, Matthew Sieber

Nat Metab. Author manuscript; available in PMC 2022 Mar 20.

Published in final edited form as: Nat Metab. 2021 Sep; 3(9): 1259–1274. Published online 2021 Sep 20. doi: 10.1038/s42255-021-00450-3

PMCID:: PMC8462065

Abstract Article PDF–4.3M

Select item 843179216.

JNK Signaling in Drosophila Aging and Longevity

Tian Gan, Lixia Fan, Long Zhao, Mala Misra, Min Liu, Min Zhang, Ying Su

Int J Mol Sci. 2021 Sep; 22(17): 9649. Published online 2021 Sep 6. doi: 10.3390/ijms22179649

PMCID:: PMC8431792

Abstract Article PDF–2.1M

Select item 841111217.

Glial glucose fuels the neuronal pentose phosphate pathway for long-term memory

Eloïse de Tredern, Yasmine Rabah, Laure Pasquer, Julia Minatchy, Pierre-Yves Plaçais, Thomas Preat

Cell Rep. 2021 Aug 24; 36(8): 109620. Published online 2021 Aug 24. doi: 10.1016/j.celrep.2021.109620

PMCID:: PMC8411112

Abstract Article

Select item 807278118.

Study on the Sleep-Improvement Effects of Hemerocallis citrina Baroni in Drosophila melanogaster and Targeted Screening to Identify Its Active Components and Mechanism

Yuxuan Liang, Riming Huang, Yongchun Chen, Jing Zhong, Jie Deng, Ziyi Wang, Zhuojun Wu, Meiying Li, Hong Wang, Yuanming Sun

Foods. 2021 Apr; 10(4): 883. Published online 2021 Apr 17. doi: 10.3390/foods10040883

PMCID:: PMC8072781

Abstract Article PDF–2.9M

Select item 799284219.

TDP-43 proteinopathy alters the ribosome association of multiple mRNAs including the glypican Dally-like protein (Dlp)/GPC6

Erik M. Lehmkuhl, Suvithanandhini Loganathan, Eric Alsop, Alexander D. Blythe, Tina Kovalik, Nicholas P. Mortimore, Dianne Barrameda, Chuol Kueth, Randall J. Eck, Bhavani B. Siddegowda, Archi Joardar, Hannah Ball, Maria E. Macias, Robert Bowser, Kendall Van Keuren-Jensen, Daniela C. Zarnescu

Acta Neuropathol Commun. 2021; 9: 52. Published online 2021 Mar 24. doi: 10.1186/s40478-021-01148-z

PMCID:: PMC7992842

Abstract Article PDF–6.3M

Select item 766130320.

Mitochondrial-Y chromosome epistasis in Drosophila melanogaster

J. Arvid Ågren, Manisha Munasinghe, Andrew G. Clark

Proc Biol Sci. 2020 Oct 28; 287(1937): 20200469. Published online 2020 Oct 21. doi: 10.1098/rspb.2020.0469

PMCID:: PMC7661303

Abstract Article PDF–883K

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