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Select item 112969141.

DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples

Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang

J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.

Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832

PMCID:: PMC11296914

Abstract Article PDF–1.7M

Select item 86641292.

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context

Marcel Morgenstern, Christian D. Peikert, Philipp Lübbert, Ida Suppanz, Cinzia Klemm, Oliver Alka, Conny Steiert, Nataliia Naumenko, Alexander Schendzielorz, Laura Melchionda, Wignand W.D. Mühlhäuser, Bettina Knapp, Jakob D. Busch, Sebastian B. Stiller, Stefan Dannenmaier, Caroline Lindau, Mariya Licheva, Christopher Eickhorst, Riccardo Galbusera, Ralf M. Zerbes, Michael T. Ryan, Claudine Kraft, Vera Kozjak-Pavlovic, Friedel Drepper, Sven Dennerlein, Silke Oeljeklaus, Nikolaus Pfanner, Nils Wiedemann, Bettina Warscheid

Cell Metab. 2021 Dec 7; 33(12): 2464–2483.e18. doi: 10.1016/j.cmet.2021.11.001

PMCID:: PMC8664129

Abstract Article

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 72268124.

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex

Marissa M. Minor, F. Blaine Hollinger, Adrienne L. McNees, Sung Yun Jung, Antrix Jain, Joseph M. Hyser, Karl-Dimiter Bissig, Betty L. Slagle

Cells. 2020 Apr; 9(4): 834. Published online 2020 Mar 30. doi: 10.3390/cells9040834

PMCID:: PMC7226812

Abstract Article PDF–2.3M

Select item 61666825.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 50825706.

Structure and biochemical properties of recombinant human dimethylglycine dehydrogenase and comparison to the disease‐related H109R variant

Peter Augustin, Altijana Hromic, Tea Pavkov‐Keller, Karl Gruber, Peter Macheroux

FEBS J. 2016 Oct; 283(19): 3587–3603. Published online 2016 Oct 6. doi: 10.1111/febs.13828

PMCID:: PMC5082570

Abstract Article PDF–1.8M

Select item 50365277.

Panorama of ancient metazoan macromolecular complexes

Cuihong Wan, Blake Borgeson, Sadhna Phanse, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Berzginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, Brent Derry, Elisabeth Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Nature. Author manuscript; available in PMC 2016 Sep 26.

Published in final edited form as: Nature. 2015 Sep 17; 525(7569): 339–344. Published online 2015 Sep 7. doi: 10.1038/nature14877

PMCID:: PMC5036527

Abstract Article PDF–4.7M

Select item 46916678.

Genetic polymorphisms that affect selenium status and response to selenium supplementation in United Kingdom pregnant women

Jinyuan Mao, Jessica J Vanderlelie, Anthony V Perkins, Christopher WG Redman, Kourosh R Ahmadi, Margaret P Rayman

Am J Clin Nutr. 2016 Jan; 103(1): 100–106. Published online 2015 Dec 16. doi: 10.3945/ajcn.115.114231

PMCID:: PMC4691667

Abstract Article PDF–488K

Select item 45122199.

Dimethylglycine Deficiency and the Development of Diabetes

Martin Magnusson, Thomas J. Wang, Clary Clish, Gunnar Engström, Peter Nilsson, Robert E. Gerszten, Olle Melander

Diabetes. 2015 Aug; 64(8): 3010–3016. Published online 2015 Mar 20. doi: 10.2337/db14-1863

PMCID:: PMC4512219

Abstract Article PDF–699K

Select item 432144410.

Genome-wide association study of selenium concentrations

Marilyn C. Cornelis, Myriam Fornage, Millennia Foy, Pengcheng Xun, Vadim N. Gladyshev, Steve Morris, Daniel I. Chasman, Frank B. Hu, Eric B. Rimm, Peter Kraft, Joanne M. Jordan, Dariush Mozaffarian, Ka He

Hum Mol Genet. 2015 Mar 1; 24(5): 1469–1477. Published online 2014 Oct 24. doi: 10.1093/hmg/ddu546

PMCID:: PMC4321444

Abstract Article PDF–252K

Select item 406425411.

An atlas of genetic influences on human blood metabolites

So-Youn Shin, Eric B. Fauman, Ann-Kristin Petersen, Jan Krumsiek, Rita Santos, Jie Huang, Matthias Arnold, Idil Erte, Vincenzo Forgetta, Tsun-Po Yang, Klaudia Walter, Cristina Menni, Lu Chen, Louella Vasquez, Ana M. Valdes, Craig L. Hyde, Vicky Wang, Daniel Ziemek, Phoebe Roberts, Li Xi, Elin Grundberg, The Multiple Tissue Human Expression Resource (MuTHER) Consortium, Melanie Waldenberger, J. Brent Richards, Robert P. Mohney, Michael V. Milburn, Sally L. John, Jeff Trimmer, Fabian J. Theis, John P. Overington, Karsten Suhre, M. Julia Brosnan, Christian Gieger, Gabi Kastenmüller, Tim D Spector, Nicole Soranzo

Nat Genet. Author manuscript; available in PMC 2014 Dec 1.

Published in final edited form as: Nat Genet. 2014 Jun; 46(6): 543–550. Published online 2014 May 11. doi: 10.1038/ng.2982

PMCID:: PMC4064254

Abstract Article PDF–2.4M

Select item 376617812.

Genome-wide association study identifies loci affecting blood copper, selenium and zinc

David M. Evans, Gu Zhu, Veronica Dy, Andrew C. Heath, Pamela A. F. Madden, John P. Kemp, George McMahon, Beate St Pourcain, Nicholas J. Timpson, Jean Golding, Debbie A. Lawlor, Colin Steer, Grant W. Montgomery, Nicholas G. Martin, George Davey Smith, John B. Whitfield

Hum Mol Genet. 2013 Oct 1; 22(19): 3998–4006. Published online 2013 May 29. doi: 10.1093/hmg/ddt239

PMCID:: PMC3766178

Abstract Article PDF–714K

Select item 366165513.

Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes

Weijia Xie, Andrew R. Wood, Valeriya Lyssenko, Michael N. Weedon, Joshua W. Knowles, Sami Alkayyali, Themistocles L. Assimes, Thomas Quertermous, Fahim Abbasi, Jussi Paananen, Hans Häring, Torben Hansen, Oluf Pedersen, Ulf Smith, Markku Laakso, the MAGIC Investigators, the DIAGRAM Consortium, the GENESIS Consortium, the RISC Consortium, Jacqueline M. Dekker, John J. Nolan, Leif Groop, Ele Ferrannini, Klaus-Peter Adam, Walter E. Gall, Timothy M. Frayling, Mark Walker

Diabetes. 2013 Jun; 62(6): 2141–2150. Published online 2013 May 17. doi: 10.2337/db12-0876

PMCID:: PMC3661655

Abstract Article PDF–575K

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 294516815.

Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study

Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators

Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452

PMCID:: PMC2945168

Abstract Article PDF–153K

Select item 294347616.

Genetic Variants in Nuclear-Encoded Mitochondrial Genes Influence AIDS Progression

Sher L. Hendrickson, James A. Lautenberger, Leslie Wei Chinn, Michael Malasky, Efe Sezgin, Lawrence A. Kingsley, James J. Goedert, Gregory D. Kirk, Edward D. Gomperts, Susan P. Buchbinder, Jennifer L. Troyer, Stephen J. O'Brien

PLoS One. 2010; 5(9): e12862. Published online 2010 Sep 21. doi: 10.1371/journal.pone.0012862

PMCID:: PMC2943476

Abstract Article PDF–461K

Select item 290133617.

Maternal Genes and Facial Clefts in Offspring: A Comprehensive Search for Genetic Associations in Two Population-Based Cleft Studies from Scandinavia

Astanand Jugessur, Min Shi, Håkon Kristian Gjessing, Rolv Terje Lie, Allen James Wilcox, Clarice Ring Weinberg, Kaare Christensen, Abee Lowman Boyles, Sandra Daack-Hirsch, Truc Trung Nguyen, Lene Christiansen, Andrew Carl Lidral, Jeffrey Clark Murray

PLoS One. 2010; 5(7): e11493. Published online 2010 Jul 9. doi: 10.1371/journal.pone.0011493

PMCID:: PMC2901336

Abstract Article PDF–778K

Select item 282835318.

Molecular basis of dimethylglycine dehydrogenase deficiency associated with pathogenic variant H109R

R. P. McAndrew, J. Vockley, J.-J. P. Kim

J Inherit Metab Dis. Author manuscript; available in PMC 2010 Feb 24.

Published in final edited form as: J Inherit Metab Dis. 2008 Dec; 31(6): 761–768. Published online 2008 Oct 21. doi: 10.1007/s10545-008-0999-2

PMCID:: PMC2828353

Abstract Article PDF–990K

Select item 277884419.

A mitochondrial protein compendium elucidates complex I disease biology

David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha

Cell. Author manuscript; available in PMC 2009 Nov 18.

Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016

PMCID:: PMC2778844

Abstract Article PDF–1.2M

Select item 277583220.

Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip

Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, Claudio Verzilli, Tom R. Gaunt, Jacky Pallas, Ruth Lovering, Kawah Li, Juan Pablo Casas, Reecha Sofat, Meena Kumari, Santiago Rodriguez, Toby Johnson, Stephen J. Newhouse, Anna Dominiczak, Nilesh J. Samani, Mark Caulfield, Peter Sever, Alice Stanton, Denis C. Shields, on behalf of the ASCOT investigators, Sandosh Padmanabhan, Olle Melander, Claire Hastie, Christian Delles, on behalf of the NORDIL investigators, Shah Ebrahim, Michael G. Marmot, George Davey Smith, Debbie A. Lawlor, Patricia B. Munroe, for the BRIGHT Consortium, Ian N. Day, Mika Kivimaki, John Whittaker, Steve E. Humphries, Aroon D. Hingorani

Am J Hum Genet. 2009 Nov 13; 85(5): 628–642. doi: 10.1016/j.ajhg.2009.10.014

PMCID:: PMC2775832

Abstract Article PDF–2.8M

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