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Select item 106631571.

The glucose transporter 2 regulates CD8⁺ T cell function via environment sensing

Hongmei Fu, Juho Vuononvirta, Silvia Fanti, Fabrizia Bonacina, Antonio D’Amati, Guosu Wang, Thanushiyan Poobalasingam, Maria Fankhaenel, Davide Lucchesi, Rachel Coleby, David Tarussio, Bernard Thorens, Robert J. Hearnden, M. Paula Longhi, Paul Grevitt, Madeeha H. Sheikh, Egle Solito, Susana A. Godinho, Michele Bombardieri, David M. Smith, Dianne Cooper, Asif J. Iqbal, Jeffrey C. Rathmell, Samuel Schaefer, Valle Morales, Katiuscia Bianchi, Giuseppe Danilo Norata, Federica M. Marelli-Berg

Nat Metab. 2023; 5(11): 1969–1985. Published online 2023 Oct 26. doi: 10.1038/s42255-023-00913-9

PMCID:: PMC10663157

Abstract Article PDF–9.6M

Select item 97127532.

Decreased expression of Glucagon-like peptide-1 receptor and Sodium-glucose co-transporter 2 in patients with proliferative diabetic retinopathy

Hui Chen, Xiongze Zhang, Nanying Liao, Yuying Ji, Lan Mi, Yuhong Gan, Yongyue Su, Feng Wen

Front Endocrinol (Lausanne) 2022; 13: 1020252. Published online 2022 Nov 17. doi: 10.3389/fendo.2022.1020252

PMCID:: PMC9712753

Abstract Article PDF–5.6M

Select item 86220883.

Evidence for a Genotype–Phenotype Correlation in Patients with Pathogenic GLUT2 (SLC2A2) Variants

Sarah C. Grünert, Anke Schumann, Federico Baronio, Konstantinos Tsiakas, Simona Murko, Ute Spiekerkoetter, René Santer

Genes (Basel) 2021 Nov; 12(11): 1785. Published online 2021 Nov 10. doi: 10.3390/genes12111785

PMCID:: PMC8622088

Abstract Article PDF–378K

Select item 83071944.

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation

Sun-Ok Kim, Kyoung Sang Cho, Bo Yeon Kim, Kyung Ho Lee

Int J Mol Sci. 2021 Jul; 22(14): 7572. Published online 2021 Jul 15. doi: 10.3390/ijms22147572

PMCID:: PMC8307194

Abstract Article PDF–2.8M

Select item 82538455.

Identification of new GLUT2-selective inhibitors through in silico ligand screening and validation in eukaryotic expression systems

Sina Schmidl, Oleg Ursu, Cristina V. Iancu, Mislav Oreb, Tudor I. Oprea, Jun-yong Choe

Sci Rep. 2021; 11: 13751. Published online 2021 Jul 2. doi: 10.1038/s41598-021-93063-5

PMCID:: PMC8253845

Abstract Article PDF–4.3M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81498277.

Decreased GLUT2 and glucose uptake contribute to insulin secretion defects in MODY3/HNF1A hiPSC-derived mutant β cells

Blaise Su Jun Low, Chang Siang Lim, Shirley Suet Lee Ding, Yaw Sing Tan, Natasha Hui Jin Ng, Vidhya Gomathi Krishnan, Su Fen Ang, Claire Wen Ying Neo, Chandra S. Verma, Shawn Hoon, Su Chi Lim, E. Shyong Tai, Adrian Kee Keong Teo

Nat Commun. 2021; 12: 3133. Published online 2021 May 25. doi: 10.1038/s41467-021-22843-4

PMCID:: PMC8149827

Abstract Article PDF–7.2M

Select item 77204038.

O⁶-methylguanine DNA methyltransferase and glucose transporter 2 in foregut and hindgut gastrointestinal neuroendocrine neoplasms

Hirofumi Watanabe, Yuto Yamazaki, Fumiyoshi Fujishima, Komoto Izumi, Masayuki Imamura, Susumu Hijioka, Kazuhiro Toriyama, Yasushi Yatabe, Atsushi Kudo, Fuyuhiko Motoi, Michiaki Unno, Hironobu Sasano

BMC Cancer. 2020; 20: 1195. Published online 2020 Dec 7. doi: 10.1186/s12885-020-07579-6

PMCID:: PMC7720403

Abstract Article PDF–2.0M

Select item 73473879.

Estimating and interpreting nonlinear receptive field of sensory neural responses with deep neural network models

Menoua Keshishian, Hassan Akbari, Bahar Khalighinejad, Jose L Herrero, Ashesh D Mehta, Nima Mesgarani

eLife. 2020; 9: e53445. Published online 2020 Jun 26. doi: 10.7554/eLife.53445

PMCID:: PMC7347387

Abstract Article PDF–1.9M

Select item 724228310.

Expressions of Carbohydrate Response Element Binding Protein and Glucose Transporters in Liver Cancer and Clinical Significance

Yu Lei, Qiaoling Hu, Jiang Gu

Pathol Oncol Res. 2020; 26(2): 1331–1340. Published online 2019 Aug 12. doi: 10.1007/s12253-019-00708-y

PMCID:: PMC7242283

Abstract Article PDF–8.1M

Select item 713753611.

Functional and Structural Analysis of Rare SLC2A2 Variants Associated with Fanconi-Bickel Syndrome and Metabolic Traits

Osatohanmwen J. Enogieru, Peter M.U. Ung, Sook Wah Yee, Avner Schlessinger, Kathleen M. Giacomini

Hum Mutat. Author manuscript; available in PMC 2020 Jul 1.

Published in final edited form as: Hum Mutat. 2019 Jul; 40(7): 983–995. Published online 2019 Apr 25. doi: 10.1002/humu.23758

PMCID:: PMC7137536

Abstract Article PDF–1.3M

Select item 685379112.

Genetic Mutations Associated with Neonatal Diabetes Mellitus in Omani Patients

Aisha Al Senani, Nishath Hamza, Hanan AlAzkawi, Manal Al Kharusi, Nashat Al Sukaiti, Maryam Al Badi, Moza Al Yahyai, Matthew Johnson, Elisa De Franco, Sarah Flanagan, Andrew Hattersley, Sian Ellard, Waad-Allah Mula-Abed

J Pediatr Endocrinol Metab. Author manuscript; available in PMC 2019 Nov 13.

Published in final edited form as: J Pediatr Endocrinol Metab. 2018 Jan 26; 31(2): 195–204. doi: 10.1515/jpem-2017-0284

PMCID:: PMC6853791

Abstract Article PDF–626K

Select item 613316813.

Physiology of renal glucose handling via SGLT1, SGLT2 and GLUT2

Chiara Ghezzi, Donald D. F. Loo, Ernest M. Wright

Diabetologia. 2018; 61(10): 2087–2097. Published online 2018 Aug 22. doi: 10.1007/s00125-018-4656-5

PMCID:: PMC6133168

Abstract Article PDF–1.4M

Select item 607772214.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Abstract Article PDF–2.4M

Select item 590990815.

Sweat glucose and GLUT2 expression in atopic dermatitis: Implication for clinical manifestation and treatment

Emi Ono, Hiroyuki Murota, Yuki Mori, Yoshichika Yoshioka, Yuko Nomura, Takichi Munetsugu, Hiroo Yokozeki, Ichiro Katayama

PLoS One. 2018; 13(4): e0195960. Published online 2018 Apr 20. doi: 10.1371/journal.pone.0195960

PMCID:: PMC5909908

Abstract Article PDF–8.1M

Select item 553161116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 500715817.

Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin

Kaixin Zhou, Sook Wah Yee, Eric L Seiser, Nienke van Leeuwen, Roger Tavendale, Amanda J Bennett, Christopher J Groves, Ruth L Coleman, Amber A van der Heijden, Joline W Beulens, Catherine E de Keyser, Linda Zaharenko, Daniel M Rotroff, Mattijs Out, Kathleen A Jablonski, Ling Chen, Martin Javorský, Jozef Židzik, Albert M Levin, L Keoki Williams, Tanja Dujic, Sabina Semiz, Michiaki Kubo, Huan-Chieh Chien, Shiro Maeda, John S Witte, Longyang Wu, Ivan Tkáč, Adriaan Kooy, Ron H N van Schaik, Coen D A Stehouwer, Lisa Logie, MetGen Investigators, DPP Investigators, ACCORD Investigators, Calum Sutherland, Janis Klovins, Valdis Pirags, Albert Hofman, Bruno H Stricker, Alison A Motsinger-Reif, Michael J Wagner, Federico Innocenti, Leen M 't Hart, Rury R Holman, Mark I McCarthy, Monique M Hedderson, Colin N A Palmer, Jose C Florez, Kathleen M Giacomini, Ewan R Pearson

Nat Genet. Author manuscript; available in PMC 2016 Sep 1.

Published in final edited form as: Nat Genet. 2016 Sep; 48(9): 1055–1059. Published online 2016 Aug 8. doi: 10.1038/ng.3632

PMCID:: PMC5007158

Abstract Article PDF–1.6M

Select item 447821618.

Association of Facilitated Glucose Transporter 2 gene variants with the Myelomeningocele phenotype

Jaclyn E Ruggiero, Hope Northrup, Kit Sing Au

Birth Defects Res A Clin Mol Teratol. Author manuscript; available in PMC 2016 Jun 1.

Published in final edited form as: Birth Defects Res A Clin Mol Teratol. 2015 Jun; 103(6): 479–487. Published online 2015 Mar 17. doi: 10.1002/bdra.23358

PMCID:: PMC4478216

Abstract Article PDF–640K

Select item 439025319.

The Last Enzyme of the De Novo Purine Synthesis Pathway 5-aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) Plays a Central Role in Insulin Signaling and the Golgi/Endosomes Protein Network

Martial Boutchueng-Djidjou, Gabriel Collard-Simard, Suzanne Fortier, Sébastien S. Hébert, Isabelle Kelly, Christian R. Landry, Robert L. Faure

Mol Cell Proteomics. 2015 Apr; 14(4): 1079–1092. Published online 2015 Feb 16. doi: 10.1074/mcp.M114.047159

PMCID:: PMC4390253

Abstract Article PDF–2.9M

Select item 382942120.

Mutations in SLC2A2 Gene Reveal hGLUT2 Function in Pancreatic β Cell Development

Aurélien Michau, Ghislaine Guillemain, Alexandra Grosfeld, Sandrine Vuillaumier-Barrot, Teddy Grand, Mathilde Keck, Sébastien L'Hoste, Danielle Chateau, Patricia Serradas, Jacques Teulon, Pascale De Lonlay, Raphaël Scharfmann, Edith Brot-Laroche, Armelle Leturque, Maude Le Gall

J Biol Chem. 2013 Oct 25; 288(43): 31080–31092. Published online 2013 Aug 28. doi: 10.1074/jbc.M113.469189

PMCID:: PMC3829421

Abstract Article PDF–3.6M

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