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Select item 107652211.

Aldo-keto Reductase 1B10 Restrains Cell Migration, Invasion, and Adhesion of Gastric Cancer via Regulating Integrin Subunit Alpha 5

Haibo Yao, Junfeng Hu, Yanfei Shao, Qinshu Shao, Shusen Zheng

Turk J Gastroenterol. 2023 Dec; 34(12): 1197–1205. Published online 2023 Dec 1. doi: 10.5152/tjg.2023.22555

PMCID:: PMC10765221

Abstract Article PDF–3.6M

Select item 105455342.

AKR1B10 regulates M2 macrophage polarization to promote the malignant phenotype of gastric cancer

Yi Wu, Yanjie Hao, Qing'xin Zhuang, Xiaoli Ma, Chao Shi

Biosci Rep. 2023 Oct 31; 43(10): BSR20222007. Published online 2023 Sep 28. doi: 10.1042/BSR20222007

PMCID:: PMC10545534

Abstract Article PDF–11M

Select item 104285993.

Warburg effect enhanced by AKR1B10 promotes acquired resistance to pemetrexed in lung cancer-derived brain metastasis

Wenzhe Duan, Wenwen Liu, Shengkai Xia, Yang Zhou, Mengyi Tang, Mingxin Xu, Manqing Lin, Xinyu Li, Qi Wang

J Transl Med. 2023; 21: 547. Published online 2023 Aug 16. doi: 10.1186/s12967-023-04403-0

PMCID:: PMC10428599

Abstract Article PDF–6.2M

Select item 98578674.

Overexpression of AKR1B10 Predicts Poor Prognosis in Gastric Cancer Patients Undergoing Surgical Resection

Yu-Yin Liu, Yueh-Wei Liu, Gong-Kai Huang, Kuo-Chen Hung, Yu-Hung Lin, Cheng-Hsi Yeh, Shih-Min Yin, Ching-Hua Tsai, Yen-Hao Chen

Curr Oncol. 2023 Jan; 30(1): 85–99. Published online 2022 Dec 21. doi: 10.3390/curroncol30010007

PMCID:: PMC9857867

Abstract Article PDF–2.1M

Select item 98519735.

A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets

Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I. Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, Savaş Tay, Glenn Randall, Peihui Wang, John T. Lis, Cédric Feschotte, Serpil C. Erzurum, Feixiong Cheng, Haiyuan Yu

Nat Biotechnol. Author manuscript; available in PMC 2023 Jan 20.

Published in final edited form as: Nat Biotechnol. 2023 Jan; 41(1): 128–139. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01474-0

PMCID:: PMC9851973

Abstract Article PDF–4.0M

Select item 97725586.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 92792857.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 91197368.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 91027269.

VCP interaction with HMGB1 promotes hepatocellular carcinoma progression by activating the PI3K/AKT/mTOR pathway

Zhangya Pu, Dan G. Duda, Yuanyuan Zhu, Siya Pei, Xiaofang Wang, Yan Huang, Panpan Yi, Zebing Huang, Fang Peng, Xingwang Hu, Xuegong Fan

J Transl Med. 2022; 20: 212. Published online 2022 May 13. doi: 10.1186/s12967-022-03416-5

PMCID:: PMC9102726

Abstract Article PDF–15M

Select item 910125310.

Plasma Aldo-Keto Reductase Family 1 Member B10 as a Biomarker Performs Well in the Diagnosis of Nonalcoholic Steatohepatitis and Fibrosis

Aron Park, Seung Joon Choi, Sungjin Park, Seong Min Kim, Hye Eun Lee, Minjae Joo, Kyoung Kon Kim, Doojin Kim, Dong Hae Chung, Jae Been Im, Jaehun Jung, Seung Kak Shin, Byung-Chul Oh, Cheolsoo Choi, Seungyoon Nam, Dae Ho Lee

Int J Mol Sci. 2022 May; 23(9): 5035. Published online 2022 May 1. doi: 10.3390/ijms23095035

PMCID:: PMC9101253

Abstract Article PDF–3.6M

Select item 899080611.

E2F1‐mediated AUF1 upregulation promotes HCC development and enhances drug resistance via stabilization of AKR1B10

Ting Zhang, Guiwen Guan, Jing Zhang, Huiling Zheng, Deyao Li, Wengong Wang, Fengmin Lu, Xiangmei Chen

Cancer Sci. 2022 Apr; 113(4): 1154–1167. Published online 2022 Feb 17. doi: 10.1111/cas.15272

PMCID:: PMC8990806

Abstract Article PDF–2.8M

Select item 883681512.

AKR1B10, One of the Triggers of Cytokine Storm in SARS-CoV2 Severe Acute Respiratory Syndrome

Clovis Chabert, Anne-Laure Vitte, Domenico Iuso, Florent Chuffart, Candice Trocme, Marlyse Buisson, Pascal Poignard, Benjamin Lardinois, Régis Debois, Sophie Rousseaux, Jean-Louis Pepin, Jean-Benoit Martinot, Saadi Khochbin

Int J Mol Sci. 2022 Feb; 23(3): 1911. Published online 2022 Feb 8. doi: 10.3390/ijms23031911

PMCID:: PMC8836815

Abstract Article PDF–2.0M

Select item 880626413.

Homeobox A5 activates p53 pathway to inhibit proliferation and promote apoptosis of adrenocortical carcinoma cells by inducing Aldo-Keto reductase family 1 member B10 expression

Danyan Chen, Zhaonan Shen, Xi Cheng, Qi Wang, Junlin Zhou, Fang Ren, Yue Sun, Hongman Wang, Rongxi Huang

Bioengineered. 2021; 12(1): 1964–1975. Published online 2021 May 23. doi: 10.1080/21655979.2021.1924545

PMCID:: PMC8806264

Abstract Article PDF–4.4M

Select item 856647314.

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma

Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim

Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6

PMCID:: PMC8566473

Abstract Article PDF–2.7M

Select item 850729215.

AKR1B10 inhibits the proliferation and migration of gastric cancer via regulating epithelial-mesenchymal transition

Xinyu Shao, Jue Wu, Shunying Yu, Yuqing Zhou, Chunli Zhou

Aging (Albany NY) 2021 Sep 30; 13(18): 22298–22314. Published online 2021 Sep 22. doi: 10.18632/aging.203538

PMCID:: PMC8507292

Abstract Article PDF–2.6M

Select item 844055116.

The expression and significance of AKR1B10 in laryngeal squamous cell carcinoma

Jixuan Liu, Hongyan Ban, Yafang Liu, Jinsong Ni

Sci Rep. 2021; 11: 18228. Published online 2021 Sep 14. doi: 10.1038/s41598-021-97648-y

PMCID:: PMC8440551

Abstract Article PDF–4.8M

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 814984918.

CBX7 suppresses urinary bladder cancer progression via modulating AKR1B10–ERK signaling

Zhengnan Huang, Yilin Yan, Zhen Zhu, Jiakuan Liu, Xiao He, Sumiya Dalangood, Meiqian Li, Mingyue Tan, Jinming Cai, Pengfei Tang, Ruimin Huang, Bing Shen, Jun Yan

Cell Death Dis. 2021 Jun; 12(6): 537. Published online 2021 May 25. doi: 10.1038/s41419-021-03819-0

PMCID:: PMC8149849

Abstract Article PDF–10M

Select item 803604119.

Prognostic value of aldo-keto reductase family 1 member B10 (AKR1B10) in digestive system cancers: A meta-analysis

Rongqiang Liu, Shiyang Zheng, Cui yan Yang, Yajie Yu, Shengjia Peng, Qianmin Ge, Qi Lin, Qiuyu Li, Wenqing Shi, Yi Shao

Medicine (Baltimore) 2021 Apr 9; 100(14): e25454. Published online 2021 Apr 9. doi: 10.1097/MD.0000000000025454

PMCID:: PMC8036041

Abstract Article PDF–894K

Select item 797570320.

AKR1B10 confers resistance to radiotherapy via FFA/TLR4/NF-κB axis in nasopharyngeal carcinoma

Xiangting Liu, Zheng Hu, Jiayao Qu, Jia Li, Ke Gong, Li Wang, Jing Jiang, Xiangning Li, Rongzhang He, Lili Duan, Weihao Luo, Chenglai Xia, Dixian Luo

Int J Biol Sci. 2021; 17(3): 756–767. Published online 2021 Feb 3. doi: 10.7150/ijbs.52927

PMCID:: PMC7975703

Abstract Article PDF–2.4M

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