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Select item 108724771.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107115592.

Elevated MSH2 MSH3 expression interferes with DNA metabolism in vivo

Melisa Medina-Rivera, Samantha Phelps, Madhumita Sridharan, Jordan Becker, Natalie A Lamb, Charanya Kumar, Mark D Sutton, Anja Bielinsky, Lata Balakrishnan, Jennifer A Surtees

Nucleic Acids Res. 2023 Dec 11; 51(22): 12185–12206. Published online 2023 Nov 1. doi: 10.1093/nar/gkad934

PMCID:: PMC10711559

Abstract Article PDF–3.2M

Select item 107001383.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 102350864.

Rio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores

Ksenia Smurova, Michela Damizia, Carmela Irene, Stefania Stancari, Giovanna Berto, Giulia Perticari, Maria Giuseppina Iacovella, Ilaria D’Ambrosio, Maria Giubettini, Réginald Philippe, Chiara Baggio, Elisabetta Callegaro, Andrea Casagranda, Alessandro Corsini, Vincenzo Gentile Polese, Anna Ricci, Erik Dassi, Peter De Wulf

Nat Commun. 2023; 14: 3172. Published online 2023 Jun 1. doi: 10.1038/s41467-023-38920-9

PMCID:: PMC10235086

Abstract Article PDF–2.6M

Select item 102333685.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 102014246.

Biochemical characterisation of Mer3 helicase interactions and the protection of meiotic recombination intermediates

Veronika Altmannova, Magdalena Firlej, Franziska Müller, Petra Janning, Rahel Rauleder, Dorota Rousova, Andreas Schäffler, Tanja Bange, John R Weir

Nucleic Acids Res. 2023 May 22; 51(9): 4363–4384. Published online 2023 Mar 21. doi: 10.1093/nar/gkad175

PMCID:: PMC10201424

Abstract Article PDF–9.0M

Select item 95862837.

The unstructured linker of Mlh1 contains a motif required for endonuclease function which is mutated in cancers

Kendall A. Torres, Felipe A. Calil, Ann L. Zhou, Matthew L. DuPrie, Christopher D. Putnam, Richard D. Kolodner

Proc Natl Acad Sci U S A. 2022 Oct 18; 119(42): e2212870119. Published online 2022 Oct 10. doi: 10.1073/pnas.2212870119

PMCID:: PMC9586283

Abstract Article PDF–1.7M

Select item 93392938.

Complex mutation profiles in mismatch repair and ribonucleotide reductase mutants reveal novel repair substrate specificity of MutS homolog (MSH) complexes

Natalie A Lamb, Jonathan E Bard, Raphael Loll-Krippleber, Grant W Brown, Jennifer A Surtees

Genetics. 2022 Aug; 221(4): iyac092. Published online 2022 Jun 10. doi: 10.1093/genetics/iyac092

PMCID:: PMC9339293

Abstract Article PDF–7.9M

Select item 92860239.

Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion

Mark Mattingly, Chris Seidel, Sofía Muñoz, Yan Hao, Ying Zhang, Zhihui Wen, Laurence Florens, Frank Uhlmann, Jennifer L. Gerton

Curr Biol. 2022 Jul 11; 32(13): 2884–2896.e6. doi: 10.1016/j.cub.2022.05.019

PMCID:: PMC9286023

Abstract Article

Select item 924339610.

Rad5 and Its Human Homologs, HLTF and SHPRH, Are Novel Interactors of Mismatch Repair

Anna K. Miller, Guogen Mao, Breanna G. Knicely, Hannah G. Daniels, Christine Rahal, Christopher D. Putnam, Richard D. Kolodner, Eva M. Goellner

Front Cell Dev Biol. 2022; 10: 843121. Published online 2022 Jun 16. doi: 10.3389/fcell.2022.843121

PMCID:: PMC9243396

Abstract Article PDF–3.4M

Select item 920981111.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 845827612.

Rad27 and Exo1 function in different excision pathways for mismatch repair in Saccharomyces cerevisiae

Felipe A. Calil, Bin-Zhong Li, Kendall A. Torres, Katarina Nguyen, Nikki Bowen, Christopher D. Putnam, Richard D. Kolodner

Nat Commun. 2021; 12: 5568. Published online 2021 Sep 22. doi: 10.1038/s41467-021-25866-z

PMCID:: PMC8458276

Abstract Article PDF–1.0M

Select item 845009913.

Handcuffing intrinsically disordered regions in Mlh1–Pms1 disrupts mismatch repair

Christopher M Furman, Ting-Yi Wang, Qiuye Zhao, Kumar Yugandhar, Haiyuan Yu, Eric Alani

Nucleic Acids Res. 2021 Sep 20; 49(16): 9327–9341. Published online 2021 Aug 14. doi: 10.1093/nar/gkab694

PMCID:: PMC8450099

Abstract Article PDF–2.0M

Select item 828138714.

Ligation of newly replicated DNA controls the timing of DNA mismatch repair

Gloria X. Reyes, Anna Kolodziejczak, Lovely Jael Paul Solomon Devakumar, Takashi Kubota, Richard D. Kolodner, Christopher D. Putnam, Hans Hombauer

Curr Biol. Author manuscript; available in PMC 2021 Jul 15.

Published in final edited form as: Curr Biol. 2021 Mar 22; 31(6): 1268–1276.e6. Published online 2021 Jan 7. doi: 10.1016/j.cub.2020.12.018

PMCID:: PMC8281387

Abstract Article PDF–1.5M

Select item 820191115.

Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation

Jingqi Dai, Aurore Sanchez, Céline Adam, Lepakshi Ranjha, Giordano Reginato, Pierre Chervy, Carine Tellier-Lebegue, Jessica Andreani, Raphaël Guérois, Virginie Ropars, Marie-Hélène Le Du, Laurent Maloisel, Emmanuelle Martini, Pierre Legrand, Aurélien Thureau, Petr Cejka, Valérie Borde, Jean-Baptiste Charbonnier

Proc Natl Acad Sci U S A. 2021 Jun 8; 118(23): e2022704118. Published online 2021 Jun 4. doi: 10.1073/pnas.2022704118

PMCID:: PMC8201911

Abstract Article PDF–2.2M

Select item 809624416.

The Pif1 helicase is actively inhibited during meiotic recombination which restrains gene conversion tract length

Dipti Vinayak Vernekar, Giordano Reginato, Céline Adam, Lepakshi Ranjha, Florent Dingli, Marie-Claude Marsolier, Damarys Loew, Raphaël Guérois, Bertrand Llorente, Petr Cejka, Valérie Borde

Nucleic Acids Res. 2021 May 7; 49(8): 4522–4533. Published online 2021 Apr 6. doi: 10.1093/nar/gkab232

PMCID:: PMC8096244

Abstract Article PDF–4.1M

Select item 773038817.

Identification of MLH2/hPMS1 dominant mutations that prevent DNA mismatch repair function

Gloria X. Reyes, Boyu Zhao, Tobias T. Schmidt, Kerstin Gries, Matthias Kloor, Hans Hombauer

Commun Biol. 2020; 3: 751. Published online 2020 Dec 10. doi: 10.1038/s42003-020-01481-4

PMCID:: PMC7730388

Abstract Article PDF–2.1M

Select item 772018318.

Exo1 recruits Cdc5 polo kinase to MutLγ to ensure efficient meiotic crossover formation

Aurore Sanchez, Céline Adam, Felix Rauh, Yann Duroc, Lepakshi Ranjha, Bérangère Lombard, Xiaojing Mu, Mélody Wintrebert, Damarys Loew, Alba Guarné, Stefano Gnan, Chun-Long Chen, Scott Keeney, Petr Cejka, Raphaël Guérois, Franz Klein, Jean-Baptiste Charbonnier, Valérie Borde

Proc Natl Acad Sci U S A. 2020 Dec 1; 117(48): 30577–30588. Published online 2020 Nov 16. doi: 10.1073/pnas.2013012117