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Select item 112945831.

Multi-signal regulation of the GSK-3β homolog Rim11 controls meiosis entry in budding yeast

Johanna Kociemba, Andreas Christ Sølvsten Jørgensen, Nika Tadić, Anthony Harris, Theodora Sideri, Wei Yee Chan, Fairouz Ibrahim, Elçin Ünal, Mark Skehel, Vahid Shahrezaei, Orlando Argüello-Miranda, Folkert Jacobus van Werven

EMBO J. 2024 Aug; 43(15): 3256–3286. Published online 2024 Jun 17. doi: 10.1038/s44318-024-00149-7

PMCID:: PMC11294583

Abstract Article PDF–5.1M

Select item 109915532.

Dbf4-dependent kinase promotes cell cycle controlled resection of DNA double-strand breaks and repair by homologous recombination

Lorenzo Galanti, Martina Peritore, Robert Gnügge, Elda Cannavo, Johannes Heipke, Maria Dilia Palumbieri, Barbara Steigenberger, Lorraine S. Symington, Petr Cejka, Boris Pfander

Nat Commun. 2024; 15: 2890. Published online 2024 Apr 3. doi: 10.1038/s41467-024-46951-z

PMCID:: PMC10991553

Abstract Article PDF–4.7M

Select item 108724773.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107001384.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 105517005.

Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability

Prashant K. Mishra, Wei-Chun Au, Pedro G. Castineira, Nazrin Ali, John Stanton, Lars Boeckmann, Yoshimitsu Takahashi, Michael Costanzo, Charles Boone, Kerry S. Bloom, Peter H. Thorpe, Munira A. Basrai

Mol Biol Cell. 2023 Sep 1; 34(10): ar99. Published online 2023 Aug 17. doi: 10.1091/mbc.E23-03-0108

PMCID:: PMC10551700

Abstract Article PDF–3.7M

Select item 97782086.

Dbf4 Zn-Finger Motif Is Specifically Required for Stimulation of Ctf19-Activated Origins in Saccharomyces cerevisiae

Meghan V. Petrie, Haiyang Zhang, Emily M. Arnold, Yan Gan, Oscar M. Aparicio

Genes (Basel) 2022 Dec; 13(12): 2202. Published online 2022 Nov 24. doi: 10.3390/genes13122202

PMCID:: PMC9778208

Abstract Article PDF–4.4M

Select item 95465317.

Rpd3 regulates single-copy origins independently of the rDNA array by opposing Fkh1-mediated origin stimulation

Yiwei He, Meghan V. Petrie, Haiyang Zhang, Jared M. Peace, Oscar M. Aparicio

Proc Natl Acad Sci U S A. 2022 Oct 4; 119(40): e2212134119. Published online 2022 Sep 26. doi: 10.1073/pnas.2212134119

PMCID:: PMC9546531

Abstract Article PDF–1.9M

Select item 93392938.

Complex mutation profiles in mismatch repair and ribonucleotide reductase mutants reveal novel repair substrate specificity of MutS homolog (MSH) complexes

Natalie A Lamb, Jonathan E Bard, Raphael Loll-Krippleber, Grant W Brown, Jennifer A Surtees

Genetics. 2022 Aug; 221(4): iyac092. Published online 2022 Jun 10. doi: 10.1093/genetics/iyac092

PMCID:: PMC9339293

Abstract Article PDF–7.9M

Select item 92098119.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 913311210.

The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer

Almutasem Saleh, Yasunori Noguchi, Ricardo Aramayo, Marina E. Ivanova, Kathryn M. Stevens, Alex Montoya, S. Sunidhi, Nicolas Lopez Carranza, Marcin J. Skwark, Christian Speck

Nat Commun. 2022; 13: 2915. Published online 2022 May 25. doi: 10.1038/s41467-022-30576-1

PMCID:: PMC9133112

Abstract Article PDF–7.2M

Select item 897681411.

Yeast Stn1 promotes MCM to circumvent Rad53 control of the S phase checkpoint

Hovik Gasparayan, Chris Caridi, Jeff Julius, Wenyi Feng, Jeff Bachant, Constance I. Nugent

Curr Genet. 2022; 68(2): 165–179. Published online 2022 Feb 12. doi: 10.1007/s00294-022-01228-0

PMCID:: PMC8976814

Abstract Article PDF–6.1M

Select item 897680912.

The yeast Dbf4 Zn²⁺ finger domain suppresses single-stranded DNA at replication forks initiated from a subset of origins

Jeff Bachant, Elizabeth A. Hoffman, Chris Caridi, Constance I. Nugent, Wenyi Feng

Curr Genet. 2022; 68(2): 253–265. Published online 2022 Feb 11. doi: 10.1007/s00294-022-01230-6

PMCID:: PMC8976809

Abstract Article PDF–4.4M

Select item 892711713.

Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase

Jiaxuan Cheng, Ningning Li, Yunjing Huo, Shangyu Dang, Bik-Kwoon Tye, Ning Gao, Yuanliang Zhai

Nat Commun. 2022; 13: 1396. Published online 2022 Mar 16. doi: 10.1038/s41467-022-29070-5

Correction in:: Nat Commun. 2022; 13: 2411.

PMCID:: PMC8927117

Abstract Article PDF–6.6M

Select item 877013114.

Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase

Julia F. Greiwe, Thomas C. R. Miller, Julia Locke, Fabrizio Martino, Steven Howell, Anne Schreiber, Andrea Nans, John F. X. Diffley, Alessandro Costa

Nat Struct Mol Biol. 2022; 29(1): 10–20. Published online 2021 Dec 28. doi: 10.1038/s41594-021-00698-z

PMCID:: PMC8770131

Abstract Article PDF–12M

Select item 857069315.

Phosphorylation of luminal region of the SUN-domain protein Mps3 promotes nuclear envelope localization during meiosis

Hanumanthu BD Prasada Rao, Takeshi Sato, Kiran Challa, Yurika Fujita, Miki Shinohara, Akira Shinohara

eLife. 2021; 10: e63119. Published online 2021 Sep 29. doi: 10.7554/eLife.63119

PMCID:: PMC8570693

Abstract Article PDF–4.7M

Select item 838702316.

Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation

Allison W McClure, John FX Diffley

eLife. 2021; 10: e69726. Published online 2021 Aug 13. doi: 10.7554/eLife.69726

PMCID:: PMC8387023

Abstract Article PDF–4.9M

Select item 792480217.

A novel role for Dun1 in the regulation of origin firing upon hyper-acetylation of H3K56

Lihi Gershon, Martin Kupiec

PLoS Genet. 2021 Feb; 17(2): e1009391. Published online 2021 Feb 18. doi: 10.1371/journal.pgen.1009391

PMCID:: PMC7924802

Abstract Article PDF–2.3M

Select item 780626618.

Checkpoint inhibition of origin firing prevents inappropriate replication outside of S-phase

Mark C Johnson, Geylani Can, Miguel Monteiro Santos, Diana Alexander, Philip Zegerman

eLife. 2021; 10: e63589. Published online 2021 Jan 5. doi: 10.7554/eLife.63589

PMCID:: PMC7806266

Abstract Article PDF–1.5M

Select item 772018319.

Exo1 recruits Cdc5 polo kinase to MutLγ to ensure efficient meiotic crossover formation

Aurore Sanchez, Céline Adam, Felix Rauh, Yann Duroc, Lepakshi Ranjha, Bérangère Lombard, Xiaojing Mu, Mélody Wintrebert, Damarys Loew, Alba Guarné, Stefano Gnan, Chun-Long Chen, Scott Keeney, Petr Cejka, Raphaël Guérois, Franz Klein, Jean-Baptiste Charbonnier, Valérie Borde

Proc Natl Acad Sci U S A. 2020 Dec 1; 117(48): 30577–30588. Published online 2020 Nov 16. doi: 10.1073/pnas.2013012117