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Select item 109425761.

Delta-dependent Notch activation closes the early neuroblast temporal program to promote lineage progression and neurogenesis termination in Drosophila

Chhavi Sood, Md Ausrafuggaman Nahid, Kendall R Branham, Matt Pahl, Susan E Doyle, Sarah E Siegrist

eLife. 2024; 12: RP88565. Published online 2024 Feb 23. doi: 10.7554/eLife.88565

PMCID:: PMC10942576

Abstract Article PDF–7.0M

Select item 106634702.

A distinct Acyl-CoA binding protein (ACBP6) shapes tissue plasticity during nutrient adaptation in Drosophila

Xiaotong Li, Jason Karpac

Nat Commun. 2023; 14: 7599. Published online 2023 Nov 21. doi: 10.1038/s41467-023-43362-4

PMCID:: PMC10663470

Abstract Article PDF–6.8M

Select item 106511103.

KDM5-mediated activation of genes required for mitochondrial biology is necessary for viability in Drosophila

Michael F. Rogers, Owen J. Marshall, Julie Secombe

Development. 2023 Nov 1; 150(21): dev202024. Published online 2023 Nov 6. doi: 10.1242/dev.202024

PMCID:: PMC10651110

Abstract Article

Select item 106489264.

Octopamine Rescues Endurance and Climbing Speed in Drosophila Clk^out Mutants with Circadian Rhythm Disruption

Maryam Safdar, Robert J. Wessells

Cells. 2023 Nov; 12(21): 2515. Published online 2023 Oct 25. doi: 10.3390/cells12212515

PMCID:: PMC10648926

Abstract Article PDF–2.7M

Select item 105234515.

Iditarod, a Drosophila homolog of the Irisin precursor FNDC5, is critical for exercise performance and cardiac autophagy

Tyler Cobb, Irene Hwang, Michael Soukar, Sim Namkoong, Uhn-Soo Cho, Maryam Safdar, Myungjin Kim, Robert J. Wessells, Jun Hee Lee

Proc Natl Acad Sci U S A. 2023 Sep 26; 120(39): e2220556120. Published online 2023 Sep 18. doi: 10.1073/pnas.2220556120

PMCID:: PMC10523451

Abstract Article PDF–3.1M

Select item 104683126.

New mutant alleles for Spargel/dPGC-1 highlights the function of Spargel RRM domain in oogenesis and expands the role of Spargel in embryogenesis and intracellular transport

Swagota D Roy, Sabarish Nagarajan, Md Shah Jalal, Md Abul Basar, Atanu Duttaroy

G3 (Bethesda) 2023 Sep; 13(9): jkad142. Published online 2023 Jun 27. doi: 10.1093/g3journal/jkad142

PMCID:: PMC10468312

Abstract Article PDF–1.0M

Select item 102641577.

Downregulation of Hsp90 and the Antimicrobial Peptide Mtk Suppresses Poly(GR)-Induced Neurotoxicity in C9ORF72-ALS/FTD

Soojin Lee, Yong-Woo Jun, Gabriel R. Linares, Brandon Butler, Yeliz Yuva-Adyemir, Jill Moore, Gopinath Krishnan, Bryan Ruiz-Juarez, Manuel Santana, Marine Pons, Neal Silverman, Zhiping Weng, Justin Ichida, Fen-Biao Gao

Neuron. Author manuscript; available in PMC 2024 May 3.

Published in final edited form as: Neuron. 2023 May 3; 111(9): 1381–1390.e6. Published online 2023 Mar 16. doi: 10.1016/j.neuron.2023.02.029

PMCID:: PMC10264157

Abstract Article PDF–1.9M

Select item 100647438.

Role of muscle FOXO gene in exercise against the skeletal muscle and cardiac age-related defects and mortality caused by high-salt intake in Drosophila

Deng-tai Wen, Ying-hui Gao, Jingfeng Wang, Shijie Wang, Qi Zhong, Wen-qi Hou

Genes Nutr. 2023; 18: 6. Published online 2023 Mar 30. doi: 10.1186/s12263-023-00725-2

PMCID:: PMC10064743

Abstract Article PDF–11M

Select item 98600839.

Stress-induced reversible cell-cycle arrest requires PRC2/PRC1-mediated control of mitophagy in Drosophila germline stem cells and human iPSCs

Tommy H. Taslim, Abdiasis M. Hussein, Riya Keshri, Julien R. Ishibashi, Tung C. Chan, Bich N. Nguyen, Shuozhi Liu, Daniel Brewer, Stuart Harper, Scott Lyons, Ben Garver, Jimmy Dang, Nanditaa Balachandar, Samriddhi Jhajharia, Debra del Castillo, Julie Mathieu, Hannele Ruohola-Baker

Stem Cell Reports. 2023 Jan 10; 18(1): 269–288. Published online 2022 Dec 8. doi: 10.1016/j.stemcr.2022.11.004

PMCID:: PMC9860083

Abstract Article PDF–6.8M

Select item 955862610.

Stimulating the sir2–spargel axis rescues exercise capacity and mitochondrial respiration in a Drosophila model of Barth syndrome

Deena Damschroder, Rubén Zapata-Pérez, Kristin Richardson, Frédéric M. Vaz, Riekelt H. Houtkooper, Robert Wessells

Dis Model Mech. 2022 Oct 1; 15(10): dmm049279. Published online 2022 Oct 5. doi: 10.1242/dmm.049279

Correction in:: Dis Model Mech. 2024 Sep 1; 17(9): dmm052040.

PMCID:: PMC9558626

Abstract Article

Select item 950700011.

Drosophila exercise, an emerging model bridging the fields of exercise and aging in human

Meng Ding, Hongyu Li, Lan Zheng

Front Cell Dev Biol. 2022; 10: 966531. Published online 2022 Sep 9. doi: 10.3389/fcell.2022.966531

PMCID:: PMC9507000

Abstract Article PDF–1.2M

Select item 935055712.

Cell-cycle exit and stem cell differentiation are coupled through regulation of mitochondrial activity in the Drosophila testis

Diego Sainz de la Maza, Silvana Hof-Michel, Lee Phillimore, Christian Bökel, Marc Amoyel

Cell Rep. 2022 May 10; 39(6): 110774. Published online 2022 May 10. doi: 10.1016/j.celrep.2022.110774

PMCID:: PMC9350557

Abstract Article

Select item 928004413.

Zika Virus Induces Sex-Dependent Metabolic Changes in Drosophila melanogaster to Promote Viral Replication

Ghada Tafesh-Edwards, Ananda Kalukin, Ioannis Eleftherianos

Front Immunol. 2022; 13: 903860. Published online 2022 Jun 30. doi: 10.3389/fimmu.2022.903860

PMCID:: PMC9280044

Abstract Article PDF–3.6M

Select item 926130714.

Drosophila Lipase 3 Mediates the Metabolic Response to Starvation and Aging

Lea Hänschke, Christoph Heier, Santiago José Maya Palacios, Huseyin Erdem Özek, Christoph Thiele, Reinhard Bauer, Ronald P. Kühnlein, Margret H. Bülow

Front Aging. 2022; 3: 800153. Published online 2022 Feb 14. doi: 10.3389/fragi.2022.800153

PMCID:: PMC9261307

Abstract Article PDF–2.8M

Select item 923968015.

An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination

Oguz Kanca, Jonathan Zirin, Yanhui Hu, Burak Tepe, Debdeep Dutta, Wen-Wen Lin, Liwen Ma, Ming Ge, Zhongyuan Zuo, Lu-Ping Liu, Robert W Levis, Norbert Perrimon, Hugo J Bellen

eLife. 2022; 11: e76077. Published online 2022 Jun 20. doi: 10.7554/eLife.76077

PMCID:: PMC9239680

Abstract Article PDF–1.2M

Select item 906500116.

Pantothenate kinase 2 interacts with PINK1 to regulate mitochondrial quality control via acetyl-CoA metabolism

Yunpeng Huang, Zhihui Wan, Yinglu Tang, Junxuan Xu, Bretton Laboret, Sree Nallamothu, Chenyu Yang, Boxiang Liu, Rongze Olivia Lu, Bingwei Lu, Juan Feng, Jing Cao, Susan Hayflick, Zhihao Wu, Bing Zhou

Nat Commun. 2022; 13: 2412. Published online 2022 May 3. doi: 10.1038/s41467-022-30178-x

PMCID:: PMC9065001

Abstract Article PDF–5.6M

Select item 896152817.

Phenotyping of Drosophila Melanogaster—A Nutritional Perspective

Virginia Eickelberg, Kai Lüersen, Stefanie Staats, Gerald Rimbach

Biomolecules. 2022 Feb; 12(2): 221. Published online 2022 Jan 27. doi: 10.3390/biom12020221

PMCID:: PMC8961528

Abstract Article PDF–7.8M

Select item 894874018.

Transfer of Human Microbiome to Drosophila Gut Model

Dongxu Ji, Hao Sun, Weichao Yang, Mingfu Gao, Hui Xu

Microorganisms. 2022 Mar; 10(3): 553. Published online 2022 Mar 3. doi: 10.3390/microorganisms10030553

PMCID:: PMC8948740

Abstract Article PDF–12M

Select item 889485419.

Functional Genomic Analysis of Amphetamine Sensitivity in Drosophila

Caline S. Karam, Brenna L. Williams, Irina Morozova, Qiaoping Yuan, Rony Panarsky, Yuchao Zhang, Colin A. Hodgkinson, David Goldman, Sergey Kalachikov, Jonathan A. Javitch

Front Psychiatry. 2022; 13: 831597. Published online 2022 Feb 18. doi: 10.3389/fpsyt.2022.831597