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Select item 111094831.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 109416552.

Structure-based engineering of Tor complexes reveals that two types of yeast TORC1 produce distinct phenotypes

Yoshiaki Kamada, Chiharu Umeda, Yukio Mukai, Hokuto Ohtsuka, Yoko Otsubo, Akira Yamashita, Takahiro Kosugi

J Cell Sci. 2024 Feb 15; 137(4): jcs261625. Published online 2024 Feb 28. doi: 10.1242/jcs.261625

PMCID:: PMC10941655

Abstract Article

Select item 108724773.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107001384.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 102977005.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 102333686.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 99376567.

Snf1/AMPK fine-tunes TORC1 signaling in response to glucose starvation

Marco Caligaris, Raffaele Nicastro, Zehan Hu, Farida Tripodi, Johannes Erwin Hummel, Benjamin Pillet, Marie-Anne Deprez, Joris Winderickx, Sabine Rospert, Paola Coccetti, Jörn Dengjel, Claudio De Virgilio

eLife. 2023; 12: e84319. Published online 2023 Feb 7. doi: 10.7554/eLife.84319

PMCID:: PMC9937656

Abstract Article PDF–8.2M

Select item 96589998.

TORC1 and PKA activity towards ribosome biogenesis oscillates in synchrony with the budding yeast cell cycle

Paolo Guerra, Luc-Alban P. E. Vuillemenot, Yulan B. van Oppen, Marije Been, Andreas Milias-Argeitis

J Cell Sci. 2022 Sep 15; 135(18): jcs260378. Published online 2022 Sep 28. doi: 10.1242/jcs.260378

PMCID:: PMC9658999

Abstract Article

Select item 95745149.

Elucidation of the interaction proteome of mitochondrial chaperone Hsp78 highlights its role in protein aggregation during heat stress

Witold Jaworek, Marc Sylvester, Giovanna Cenini, Wolfgang Voos

J Biol Chem. 2022 Oct; 298(10): 102494. Published online 2022 Sep 15. doi: 10.1016/j.jbc.2022.102494

PMCID:: PMC9574514

Abstract Article PDF–1.9M

Select item 928602310.

Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion

Mark Mattingly, Chris Seidel, Sofía Muñoz, Yan Hao, Ying Zhang, Zhihui Wen, Laurence Florens, Frank Uhlmann, Jennifer L. Gerton

Curr Biol. 2022 Jul 11; 32(13): 2884–2896.e6. doi: 10.1016/j.cub.2022.05.019

PMCID:: PMC9286023

Abstract Article

Select item 920981111.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 804637612.

Kog1/Raptor mediates metabolic rewiring during nutrient limitation by controlling SNF1/AMPK activity

Zeenat Rashida, Rajalakshmi Srinivasan, Meghana Cyanam, Sunil Laxman

Sci Adv. 2021 Apr; 7(16): eabe5544. Published online 2021 Apr 14. doi: 10.1126/sciadv.abe5544

PMCID:: PMC8046376

Abstract Article PDF–1.1M

Select item 787948213.

Analysis of the TORC1 interactome reveals a spatially distinct function of TORC1 in mRNP complexes

Yeonji Chang, Gyubum Lim, Won-Ki Huh

J Cell Biol. 2021 Apr 5; 220(4): e201912060. Published online 2021 Feb 10. doi: 10.1083/jcb.201912060

PMCID:: PMC7879482

Abstract Article PDF–5.9M

Select item 771875114.

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1

Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman

G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709

PMCID:: PMC7718751

Abstract Article PDF–1.2M

Select item 770806315.

The catalytic activity of the translation termination factor methyltransferase Mtq2-Trm112 complex is required for large ribosomal subunit biogenesis

Caroline Lacoux, Ludivine Wacheul, Kritika Saraf, Nicolas Pythoud, Emmeline Huvelle, Sabine Figaro, Marc Graille, Christine Carapito, Denis L J Lafontaine, Valérie Heurgué-Hamard

Nucleic Acids Res. 2020 Dec 2; 48(21): 12310–12325. Published online 2020 Nov 9. doi: 10.1093/nar/gkaa972

PMCID:: PMC7708063

Abstract Article PDF–4.8M

Select item 766412216.

The Capture of a Disabled Proteasome Identifies Erg25 as a Substrate for Endoplasmic Reticulum Associated Degradation

Teresa M. Buck, Xuemei Zeng, Pamela S. Cantrell, Richard T. Cattley, Zikri Hasanbasri, Megan E. Yates, Diep Nguyen, Nathan A. Yates, Jeffrey L. Brodsky

Mol Cell Proteomics. 2020 Nov; 19(11): 1896–1909. Published online 2020 Aug 31. doi: 10.1074/mcp.RA120.002050

PMCID:: PMC7664122

Abstract Article PDF–1.2M

Select item 759291717.

The Ccr4-Not complex regulates TORC1 signaling and mitochondrial metabolism by promoting vacuole V-ATPase activity

Hongfeng Chen, P. Winston Miller, Daniel L. Johnson, R. Nicholas Laribee

PLoS Genet. 2020 Oct; 16(10): e1009046. Published online 2020 Oct 16. doi: 10.1371/journal.pgen.1009046

PMCID:: PMC7592917

Abstract Article PDF–3.2M

Select item 675205318.

Yeast ataxin-2 forms an intracellular condensate required for the inhibition of TORC1 signaling during respiratory growth

Yu-San Yang, Masato Kato, Xi Wu, Athanasios Litsios, Benjamin M. Sutter, Yun Wang, Chien-Hsiang Hsu, N. Ezgi Wood, Andrew Lemoff, Hamid Mirzaei, Matthias Heinemann, Benjamin P. Tu

Cell. Author manuscript; available in PMC 2020 Apr 18.

Published in final edited form as: Cell. 2019 Apr 18; 177(3): 697–710.e17. Published online 2019 Apr 11. doi: 10.1016/j.cell.2019.02.043

PMCID:: PMC6752053

Abstract Article PDF–1.3M

Select item 671577419.

Network Rewiring of Homologous Recombination Enzymes during Mitotic Proliferation and Meiosis

Philipp Wild, Aitor Susperregui, Ilaria Piazza, Christian Dörig, Ashwini Oke, Meret Arter, Miyuki Yamaguchi, Alexander T. Hilditch, Karla Vuina, Ki Choi Chan, Tatiana Gromova, James E. Haber, Jennifer C. Fung, Paola Picotti, Joao Matos

Mol Cell. 2019 Aug 22; 75(4): 859–874.e4. doi: 10.1016/j.molcel.2019.06.022