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Select item 105503211.

Mitochondrial superoxide dismutase Sod2 suppresses nuclear genome instability during oxidative stress

Sonia Vidushi Gupta, Lillian Campos, Kristina Hildegard Schmidt

Genetics. 2023 Oct; 225(2): iyad147. Published online 2023 Aug 29. doi: 10.1093/genetics/iyad147

PMCID:: PMC10550321

Abstract Article PDF–1.2M

Select item 104712002.

Genetic control of the error-prone repair of a chromosomal double-strand break with 5′ overhangs in yeast

Samantha Shaltz, Sue Jinks-Robertson

Genetics. 2023 Sep; 225(1): iyad122. Published online 2023 Jul 8. doi: 10.1093/genetics/iyad122

PMCID:: PMC10471200

Abstract Article PDF–725K

Select item 102333683.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 99570474.

A Role for the Interactions between Polδ and PCNA Revealed by Analysis of pol3-01 Yeast Mutants

Shaked Nir Heyman, Mika Golan, Batia Liefshitz, Martin Kupiec

Genes (Basel) 2023 Feb; 14(2): 391. Published online 2023 Feb 2. doi: 10.3390/genes14020391

PMCID:: PMC9957047

Abstract Article PDF–1.8M

Select item 99374895.

Rad51 filaments assembled in the absence of the complex formed by the Rad51 paralogs Rad55 and Rad57 are outcompeted by translesion DNA polymerases on UV-induced ssDNA gaps

Laurent Maloisel, Emilie Ma, Jamie Phipps, Alice Deshayes, Stefano Mattarocci, Stéphane Marcand, Karine Dubrana, Eric Coïc

PLoS Genet. 2023 Feb; 19(2): e1010639. Published online 2023 Feb 7. doi: 10.1371/journal.pgen.1010639

PMCID:: PMC9937489

Abstract Article PDF–2.6M

Select item 99261206.

Evolution of Rev7 interactions in eukaryotic TLS DNA polymerase Polζ

Kerry Silva McPherson, Alessandro A. Rizzo, Heidi Erlandsen, Nimrat Chatterjee, Graham C. Walker, Dmitry M. Korzhnev

J Biol Chem. 2023 Feb; 299(2): 102859. Published online 2022 Dec 31. doi: 10.1016/j.jbc.2022.102859

PMCID:: PMC9926120

Abstract Article PDF–3.3M

Select item 92098117.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 88871268.

Parental histone deposition on the replicated strands promotes error-free DNA damage tolerance and regulates drug resistance

Valeria Dolce, Sabrina Dusi, Michele Giannattasio, Chinnu Rose Joseph, Marco Fumasoni, Dana Branzei

Genes Dev. 2022 Feb 1; 36(3-4): 167–179. doi: 10.1101/gad.349207.121

PMCID:: PMC8887126

Abstract Article PDF–16M

Select item 83195319.

Cryo-EM reveals conformational flexibility in apo DNA polymerase ζ

Chloe Du Truong, Theodore A. Craig, Gaofeng Cui, Maria Victoria Botuyan, Rachel A. Serkasevich, Ka-Yi Chan, Georges Mer, Po-Lin Chiu, Rajiv Kumar

J Biol Chem. 2021 Aug; 297(2): 100912. Published online 2021 Jun 24. doi: 10.1016/j.jbc.2021.100912

PMCID:: PMC8319531

Abstract Article PDF–2.1M

Select item 822535210.

Compensation for the absence of the catalytically active half of DNA polymerase ε in yeast by positively selected mutations in CDC28

Elena I Stepchenkova, Anna S Zhuk, Jian Cui, Elena R Tarakhovskaya, Stephanie R Barbari, Polina V Shcherbakova, Dmitrii E Polev, Roman Fedorov, Eugenia Poliakov, Igor B Rogozin, Artem G Lada, Youri I Pavlov

Genetics. 2021 Jun; 218(2): iyab060. Published online 2021 Apr 12. doi: 10.1093/genetics/iyab060

PMCID:: PMC8225352

Abstract Article PDF–1.7M

Select item 789130211.

Regulation of UV damage repair in quiescent yeast cells

Lindsey J. Long, Po-Hsuen Lee, Eric M. Small, Cory Hillyer, Yan Guo, Mary Ann Osley

DNA Repair (Amst) Author manuscript; available in PMC 2021 Feb 18.

Published in final edited form as: DNA Repair (Amst). 2020 Jun; 90: 102861. Published online 2020 Apr 30. doi: 10.1016/j.dnarep.2020.102861

PMCID:: PMC7891302

Abstract Article PDF–1018K

Select item 786153112.

Limiting DNA polymerase delta alters replication dynamics and leads to a dependence on checkpoint activation and recombination-mediated DNA repair

Natasha C. Koussa, Duncan J. Smith

PLoS Genet. 2021 Jan; 17(1): e1009322. Published online 2021 Jan 25. doi: 10.1371/journal.pgen.1009322

PMCID:: PMC7861531

Abstract Article PDF–1.9M

Select item 776297413.

Recombination and Pol ζ Rescue Defective DNA Replication upon Impaired CMG Helicase—Pol ε Interaction

Milena Denkiewicz-Kruk, Malgorzata Jedrychowska, Shizuko Endo, Hiroyuki Araki, Piotr Jonczyk, Michal Dmowski, Iwona J. Fijalkowska

Int J Mol Sci. 2020 Dec; 21(24): 9484. Published online 2020 Dec 13. doi: 10.3390/ijms21249484

PMCID:: PMC7762974

Abstract Article PDF–2.8M

Select item 771875114.

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1

Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman

G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709

PMCID:: PMC7718751

Abstract Article PDF–1.2M

Select item 755408815.

Structure and Mechanism of B-family DNA Polymerase ζ Specialized for Translesion DNA Synthesis

Radhika Malik, Mykhailo Kopylov, Yacob Gomez-Llorente, Rinku Jain, Robert E. Johnson, Louise Prakash, Satya Prakash, Iban Ubarretxena-Belandia, Aneel K. Aggarwal

Nat Struct Mol Biol. Author manuscript; available in PMC 2021 Feb 17.

Published in final edited form as: Nat Struct Mol Biol. 2020 Oct; 27(10): 913–924. Published online 2020 Aug 17. doi: 10.1038/s41594-020-0476-7

PMCID:: PMC7554088

Abstract Article PDF–7.0M

Select item 754721116.

Trajectory and uniqueness of mutational signatures in yeast mutators

Sophie Loeillet, Mareike Herzog, Fabio Puddu, Patricia Legoix, Sylvain Baulande, Stephen P. Jackson, Alain G. Nicolas

Proc Natl Acad Sci U S A. 2020 Oct 6; 117(40): 24947–24956. Published online 2020 Sep 23. doi: 10.1073/pnas.2011332117

PMCID:: PMC7547211

Abstract Article PDF–1.8M

Select item 750254517.

Genetic characterization of three distinct mechanisms supporting RNA-driven DNA repair and modification reveals major role of DNA polymerase ζ

Chance Meers, Havva Keskin, Gabor Banyai, Olga Mazina, Taehwan Yang, Alli L. Gombolay, Kuntal Mukherjee, Efiyenia I. Kaparos, Gary Newnam, Alexander Mazin, Francesca Storici

Mol Cell. Author manuscript; available in PMC 2021 Sep 17.

Published in final edited form as: Mol Cell. 2020 Sep 17; 79(6): 1037–1050.e5. Published online 2020 Sep 2. doi: 10.1016/j.molcel.2020.08.011

PMCID:: PMC7502545

Abstract Article PDF–1.9M

Select item 747097818.

Bypass of DNA interstrand crosslinks by a Rev1–DNA polymerase ζ complex

Rachel Bezalel-Buch, Young K Cheun, Upasana Roy, Orlando D Schärer, Peter M Burgers

Nucleic Acids Res. 2020 Sep 4; 48(15): 8461–8473. Published online 2020 Jul 7. doi: 10.1093/nar/gkaa580

PMCID:: PMC7470978

Abstract Article PDF–5.0M

Select item 737474619.

Ethanol exposure increases mutation rate through error-prone polymerases

Karin Voordeckers, Camilla Colding, Lavinia Grasso, Benjamin Pardo, Lore Hoes, Jacek Kominek, Kim Gielens, Kaat Dekoster, Jonathan Gordon, Elisa Van der Zande, Peter Bircham, Toon Swings, Jan Michiels, Peter Van Loo, Sandra Nuyts, Philippe Pasero, Michael Lisby, Kevin J. Verstrepen

Nat Commun. 2020; 11: 3664. Published online 2020 Jul 21. doi: 10.1038/s41467-020-17447-3