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Select item 109578971.

An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway

Grace Y. Liu, Patrick Jouandin, Raymond E. Bahng, Norbert Perrimon, David M. Sabatini

Nat Commun. 2024; 15: 2517. Published online 2024 Mar 21. doi: 10.1038/s41467-024-46680-3

PMCID:: PMC10957897

Abstract Article PDF–2.0M

Select item 108574342.

Stem cell mTOR signaling directs region-specific cell fate decisions during intestinal nutrient adaptation

Jaakko Mattila, Arto Viitanen, Gaia Fabris, Tetiana Strutynska, Jerome Korzelius, Ville Hietakangas

Sci Adv. 2024 Feb 9; 10(6): eadi2671. Published online 2024 Feb 9. doi: 10.1126/sciadv.adi2671

PMCID:: PMC10857434

Abstract Article PDF–11M

Select item 102049573.

TORC1 regulation of dendrite regrowth after pruning is linked to actin and exocytosis

Neeraja Sanal, Lorena Keding, Ulrike Gigengack, Esther Michalke, Sebastian Rumpf

PLoS Genet. 2023 May; 19(5): e1010526. Published online 2023 May 11. doi: 10.1371/journal.pgen.1010526

PMCID:: PMC10204957

Abstract Article PDF–4.4M

Select item 99104874.

Wdr59 promotes or inhibits TORC1 activity depending on cellular context

Yingbiao Zhang, Chun-Yuan Ting, Shu Yang, John Reich, Karenne Fru, Mary A. Lilly

Proc Natl Acad Sci U S A. 2023 Jan 3; 120(1): e2212330120. Published online 2022 Dec 28. doi: 10.1073/pnas.2212330120

PMCID:: PMC9910487

Abstract Article PDF–7.5M

Select item 88330925.

An intestinal zinc sensor regulates food intake and developmental growth

Siamak Redhai, Clare Pilgrim, Pedro Gaspar, Lena van Giesen, Tatiana Lopes, Olena Riabinina, Théodore Grenier, Alexandra Milona, Bhavna Chanana, Jacob B. Swadling, Yi-Fang Wang, Farah Dahalan, Michaela Yuan, Michaela Wilsch-Brauninger, Wei-hsiang Lin, Nathan Dennison, Paolo Capriotti, Mara K.N. Lawniczak, Richard A. Baines, Tobias Warnecke, Nikolai Windbichler, Francois Leulier, Nicholas Bellono, Irene Miguel-Aliaga

Nature. Author manuscript; available in PMC 2022 Feb 11.

Published in final edited form as: Nature. 2020 Apr; 580(7802): 263–268. Published online 2020 Mar 18. doi: 10.1038/s41586-020-2111-5

PMCID:: PMC8833092

Abstract Article PDF–6.2M

Select item 85284896.

Multiscale analysis reveals that diet-dependent midgut plasticity emerges from alterations in both stem cell niche coupling and enterocyte size

Alessandro Bonfini, Adam J Dobson, David Duneau, Jonathan Revah, Xi Liu, Philip Houtz, Nicolas Buchon

eLife. 2021; 10: e64125. Published online 2021 Sep 23. doi: 10.7554/eLife.64125

PMCID:: PMC8528489

Abstract Article PDF–12M

Select item 82018547.

Genetic basis of variation in cocaine and methamphetamine consumption in outbred populations of Drosophila melanogaster

Brandon M. Baker, Mary Anna Carbone, Wen Huang, Robert R. H. Anholt, Trudy F. C. Mackay

Proc Natl Acad Sci U S A. 2021 Jun 8; 118(23): e2104131118. Published online 2021 May 31. doi: 10.1073/pnas.2104131118

PMCID:: PMC8201854

Abstract Article PDF–1.3M

Select item 76579778.

The Rag GTPase regulates the dynamic behavior of TSC downstream of both amino acid and growth factor restriction

Shu Yang, Yingbiao Zhang, Chun-Yuan Ting, Lucia Bettedi, Kuikwon Kim, Elena Ghaniam, Mary Lilly

Dev Cell. Author manuscript; available in PMC 2021 Nov 9.

Published in final edited form as: Dev Cell. 2020 Nov 9; 55(3): 272–288.e5. Published online 2020 Sep 7. doi: 10.1016/j.devcel.2020.08.006

PMCID:: PMC7657977

Abstract Article PDF–3.2M

Select item 75501929.

Topology-driven protein-protein interaction network analysis detects genetic sub-networks regulating reproductive capacity

Tarun Kumar, Leo Blondel, Cassandra G Extavour

eLife. 2020; 9: e54082. Published online 2020 Sep 9. doi: 10.7554/eLife.54082

PMCID:: PMC7550192

Abstract Article PDF–2.8M

Select item 753685410.

Regulation of Body Size and Growth Control

Michael J. Texada, Takashi Koyama, Kim Rewitz

Genetics. 2020 Oct; 216(2): 269–313. Published online 2020 Jul 6. doi: 10.1534/genetics.120.303095

PMCID:: PMC7536854

Abstract Article PDF–2.2M

Select item 746858311.

Mislocalization of TORC1 to Lysosomes Caused by KIF11 Inhibition Leads to Aberrant TORC1 Activity

Yoon-Gu Jang, Yujin Choi, Kyoungho Jun, Jongkyeong Chung

Mol Cells. 2020 Aug 31; 43(8): 705–717. Published online 2020 Aug 7. doi: 10.14348/molcells.2020.0089

PMCID:: PMC7468583

Abstract Article PDF–5.6M

Select item 696157812.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 614032413.

Rab6 promotes insulin receptor and cathepsin trafficking to regulate autophagy induction and activity in Drosophila

Carlos I. Ayala, Jung Kim, Thomas P. Neufeld

J Cell Sci. 2018 Sep 1; 131(17): jcs216127. Published online 2018 Sep 7. doi: 10.1242/jcs.216127

PMCID:: PMC6140324

Abstract Article

Select item 600332814.

Steroid signaling mediates nutritional regulation of juvenile body growth via IGF-binding protein in Drosophila

Gang Jun Lee, Gangsik Han, Hyun Myoung Yun, Jin Ju Lim, Sujin Noh, Jaegeun Lee, Seogang Hyun

Proc Natl Acad Sci U S A. 2018 Jun 5; 115(23): 5992–5997. Published online 2018 May 21. doi: 10.1073/pnas.1718834115

PMCID:: PMC6003328

Abstract Article PDF–981K

Select item 570780515.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900216.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 556048917.

Acute dietary restriction acts via TOR, PP2A, and Myc signaling to boost innate immunity in Drosophila

Jung-Eun Lee, Morsi Rayyan, Allison Liao, Isaac Edery, Scott D Pletcher

Cell Rep. Author manuscript; available in PMC 2017 Aug 17.

Published in final edited form as: Cell Rep. 2017 Jul 11; 20(2): 479–490. doi: 10.1016/j.celrep.2017.06.052

PMCID:: PMC5560489

Abstract Article PDF–1.0M

Select item 549917418.

Genetic Dissection of Nutrition-Induced Plasticity in Insulin/Insulin-Like Growth Factor Signaling and Median Life Span in a Drosophila Multiparent Population

Patrick D. Stanley, Enoch Ng’oma, Siri O’Day, Elizabeth G. King

Genetics. 2017 Jun; 206(2): 587–602. Published online 2017 Jun 6. doi: 10.1534/genetics.116.197780

PMCID:: PMC5499174

Abstract Article PDF–1.7M

Select item 529832419.

Nutrient-Dependent Endocycling in Steroidogenic Tissue Dictates Timing of Metamorphosis in Drosophila melanogaster

Yuya Ohhara, Satoru Kobayashi, Naoki Yamanaka

PLoS Genet. 2017 Jan; 13(1): e1006583. Published online 2017 Jan 25. doi: 10.1371/journal.pgen.1006583

PMCID:: PMC5298324

Abstract Article PDF–3.0M

Select item 512431120.

The Drosophila transcriptional network is structured by microbiota

Adam J. Dobson, John M. Chaston, Angela E. Douglas

BMC Genomics. 2016; 17: 975. Published online 2016 Nov 25. doi: 10.1186/s12864-016-3307-9

Correction in:: BMC Genomics. 2017; 18: 124.

PMCID:: PMC5124311

Abstract Article PDF–1.1M

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