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Select item 112684341.

RhoA-LIMK Signaling Axis Reveals Rostral-Caudal Plane and Spatial Dysregulation in the Brain of Alzheimer’s Disease Mouse Models

Shayan Nik Akhtar, Qun Lu

J Alzheimers Dis. Author manuscript; available in PMC 2024 Jul 24.

Published in final edited form as: J Alzheimers Dis. 2023; 95(4): 1643–1656. doi: 10.3233/JAD-230408

PMCID:: PMC11268434

Abstract Article PDF–3.3M

Select item 96125222.

Inka2, a novel Pak4 inhibitor, regulates actin dynamics in neuronal development

Seiya Yamada, Tomoya Mizukoshi, Akinori Tokunaga, Shin-ichi Sakakibara

PLoS Genet. 2022 Oct; 18(10): e1010438. Published online 2022 Oct 27. doi: 10.1371/journal.pgen.1010438

PMCID:: PMC9612522

Abstract Article PDF–4.8M

Select item 93485763.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 83145294.

Overexpression of LIMK1 in hippocampal excitatory neurons improves synaptic plasticity and social recognition memory in APP/PS1 mice

Haiwang Zhang, Youssif Ben Zablah, An Liu, Dongju Lee, Haorui Zhang, Yanghong Meng, Changxi Zhou, Xingde Liu, Yiming Wang, Zhengping Jia

Mol Brain. 2021; 14: 121. Published online 2021 Jul 27. doi: 10.1186/s13041-021-00833-3

PMCID:: PMC8314529

Abstract Article PDF–2.6M

Select item 80470195.

Spine impairment in mice high-expressing neuregulin 1 due to LIMK1 activation

Peng Chen, Hongyang Jing, Mingtao Xiong, Qian Zhang, Dong Lin, Dongyan Ren, Shunqi Wang, Dongmin Yin, Yongjun Chen, Tian Zhou, Baoming Li, Erkang Fei, Bing-Xing Pan

Cell Death Dis. 2021 Apr; 12(4): 403. Published online 2021 Apr 14. doi: 10.1038/s41419-021-03687-8

PMCID:: PMC8047019

Abstract Article PDF–4.8M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 68678217.

The Cofilin/Limk1 Pathway Controls the Growth Rate of Both Developing and Regenerating Motor Axons

Michele E. Frendo, Alexandra da Silva, Keith D. Phan, Soizic Riche, Samantha J. Butler

J Neurosci. 2019 Nov 20; 39(47): 9316–9327. doi: 10.1523/JNEUROSCI.0648-19.2019

PMCID:: PMC6867821

Abstract Article PDF–5.1M

Select item 66649108.

Reelin Stabilizes the Actin Cytoskeleton of Neuronal Processes by Inducing n-Cofilin Phosphorylation at Serine3

Xuejun Chai, Eckart Förster, Shanting Zhao, Hans H. Bock, Michael Frotscher

J Neurosci. 2009 Jan 7; 29(1): 288–299. doi: 10.1523/JNEUROSCI.2934-08.2009

PMCID:: PMC6664910

Abstract Article PDF–786K

Select item 66375589.

LIMK1 and LIMK2 regulate cortical development through affecting neural progenitor cell proliferation and migration

Rui Mao, Rui Deng, Yan Wei, Lifang Han, Yanghong Meng, Wei Xie, Zhengping Jia

Mol Brain. 2019; 12: 67. Published online 2019 Jul 18. doi: 10.1186/s13041-019-0487-7

PMCID:: PMC6637558

Abstract Article PDF–3.4M

Select item 663294410.

GluA2 (GluR2) Regulates Metabotropic Glutamate Receptor-Dependent Long-Term Depression through N-Cadherin-Dependent and Cofilin-Mediated Actin Reorganization

Zikai Zhou, Jim Hu, Maria Passafaro, Wei Xie, Zhengping Jia

J Neurosci. 2011 Jan 19; 31(3): 819–833. doi: 10.1523/JNEUROSCI.3869-10.2011

PMCID:: PMC6632944

Abstract Article PDF–3.0M

Select item 651441511.

Secretory pathway calcium ATPase 1 (SPCA1) controls mouse neural tube closure by regulating cytoskeletal dynamics

Joel M. Brown, María J. García-García

Development. 2018 Oct 1; 145(19): dev170019. Published online 2018 Oct 5. doi: 10.1242/dev.170019

PMCID:: PMC6514415

Abstract Article

Select item 639924912.

Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function

Qiaojun Fang, Yuhua Zhang, Peng Da, Buwei Shao, Haolai Pan, Zuhong He, Cheng Cheng, Dan Li, Jiaqi Guo, Xiaohan Wu, Ming Guan, Menghui Liao, Yuan Zhang, Suhua Sha, Zikai Zhou, Jian Wang, Tian Wang, Kaiming Su, Renjie Chai, Fangyi Chen

Sci Rep. 2019; 9: 3357. Published online 2019 Mar 4. doi: 10.1038/s41598-019-39769-z

PMCID:: PMC6399249

Abstract Article PDF–6.2M

Select item 634940713.

Correct setup of the substantia nigra requires Reelin-mediated fast, laterally-directed migration of dopaminergic neurons

Ankita Ravi Vaswani, Beatrice Weykopf, Cathleen Hagemann, Hans-Ulrich Fried, Oliver Brüstle, Sandra Blaess

eLife. 2019; 8: e41623. Published online 2019 Jan 28. doi: 10.7554/eLife.41623

PMCID:: PMC6349407

Abstract Article PDF–5.2M

Select item 617601014.

Loss of ARHGEF6 Causes Hair Cell Stereocilia Deficits and Hearing Loss in Mice

Chengwen Zhu, Cheng Cheng, Yanfei Wang, Waqas Muhammad, Shuang Liu, Weijie Zhu, Buwei Shao, Zhong Zhang, Xiaoqian Yan, Qingqing He, Zhengrong Xu, Chenjie Yu, Xiaoyun Qian, Ling Lu, Shasha Zhang, Yuan Zhang, Wei Xiong, Xia Gao, Zhigang Xu, Renjie Chai

Front Mol Neurosci. 2018; 11: 362. Published online 2018 Oct 2. doi: 10.3389/fnmol.2018.00362

PMCID:: PMC6176010

Abstract Article PDF–7.8M

Select item 611058315.

Involvement of LIMK1/2 in actin assembly during mouse embryo development

Xing Duan, Hao-Lin Zhang, Lan-Lan Wu, Meng-Yao Liu, Meng-Hao Pan, Xiang-Hong Ou, Shao-Chen Sun

Cell Cycle. 2018; 17(11): 1381–1389. Published online 2018 Jul 25. doi: 10.1080/15384101.2018.1482138

PMCID:: PMC6110583

Abstract Article PDF–1.6M

Select item 581800916.

The developmental and genetic basis of ‘clubfoot’ in the peroneal muscular atrophy mutant mouse

J. Martin Collinson, Nils O. Lindström, Carlos Neves, Karen Wallace, Caroline Meharg, Rebecca H. Charles, Zoe K. Ross, Amy M. Fraser, Ivan Mbogo, Kadri Oras, Masaru Nakamoto, Simon Barker, Suzanne Duce, Zosia Miedzybrodzka, Neil Vargesson

Development. 2018 Feb 1; 145(3): dev160093. doi: 10.1242/dev.160093

PMCID:: PMC5818009

Abstract Article

Select item 556184817.

A conserved region in the 3′ untranslated region of the human LIMK1 gene is critical for proper expression of LIMK1 at the post-transcriptional level

Guang-Fei Deng, Shu-Jing Liu, Xun-Sha Sun, Wei-Wen Sun, Qi-Hua Zhao, Wei-Ping Liao, Yong-Hong Yi, Yue-Sheng Long

Neurosci Bull. 2013 Jun; 29(3): 348–354. Published online 2013 May 23. doi: 10.1007/s12264-013-1341-z

PMCID:: PMC5561848

Abstract Article PDF–627K

Select item 555734418.

Hyperactive locomotion in a Drosophila model is a functional readout for the synaptic abnormalities underlying fragile X syndrome

Risa Kashima, Patrick L. Redmond, Prajakta Ghatpande, Sougata Roy, Thomas B. Kornberg, Thomas Hanke, Stefan Knapp, Giorgio Lagna, Akiko Hata

Sci Signal. Author manuscript; available in PMC 2017 Aug 15.

Published in final edited form as: Sci Signal. 2017 May 2; 10(477): eaai8133. Published online 2017 May 2. doi: 10.1126/scisignal.aai8133

PMCID:: PMC5557344

Abstract Article PDF–763K

Select item 527471919.

Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome

Risa Kashima, Sougata Roy, Manuel Ascano, Veronica Martinez-Cerdeno, Jeanelle Ariza-Torres, Sunghwan Kim, Justin Louie, Yao Lu, Patricio Leyton, Kenneth D. Bloch, Thomas B. Kornberg, Paul J. Hagerman, Randi Hagerman, Giorgio Lagna, Akiko Hata

Sci Signal. Author manuscript; available in PMC 2017 Jan 29.

Published in final edited form as: Sci Signal. 2016 Jun 7; 9(431): ra58. Published online 2016 Jun 7. doi: 10.1126/scisignal.aaf6060

PMCID:: PMC5274719

Abstract Article PDF–3.2M

Select item 501028420.

Coordination of Cellular Dynamics Contributes to Tooth Epithelium Deformations

Ritsuko Morita, Miho Kihira, Yousuke Nakatsu, Yohei Nomoto, Miho Ogawa, Kazumasa Ohashi, Kensaku Mizuno, Tetsuhiko Tachikawa, Yukitaka Ishimoto, Yoshihiro Morishita, Takashi Tsuji

PLoS One. 2016; 11(9): e0161336. Published online 2016 Sep 2. doi: 10.1371/journal.pone.0161336

PMCID:: PMC5010284

Abstract Article PDF–10M

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