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Select item 111637961.

Neutrophil-specific expression of JAK2-V617F or CALRmut induces distinct inflammatory profiles in myeloproliferative neoplasia

Tobias Ronny Haage, Emmanouil Charakopoulos, Vikas Bhuria, Conny K. Baldauf, Mark Korthals, Juliane Handschuh, Peter Müller, Juan Li, Kunjan Harit, Gopala Nishanth, Stephanie Frey, Martin Böttcher, Klaus-Dieter Fischer, Jan Dudeck, Anne Dudeck, Daniel B. Lipka, Burkhart Schraven, Anthony R. Green, Andreas J. Müller, Dimitrios Mougiakakos, Thomas Fischer

J Hematol Oncol. 2024; 17: 43. Published online 2024 Jun 9. doi: 10.1186/s13045-024-01562-5

PMCID:: PMC11163796

Abstract Article PDF–10M

Select item 110289862.

Involvement of damage-associated molecular patterns in tumor response to photodynamic therapy: surface expression of calreticulin and high-mobility group box-1 release

Mladen Korbelik, Wei Zhang, Soroush Merchant

Cancer Immunol Immunother. 2011 Oct; 60(10): 1431–1437. Published online 2011 Jun 5. doi: 10.1007/s00262-011-1047-x

PMCID:: PMC11028986

Abstract Article PDF–1.8M

Select item 108374583.

Calreticulin and JAK2V617F driver mutations induce distinct mitotic defects in myeloproliferative neoplasms

Kristin Holl, Nicolas Chatain, Susanne Krapp, Julian Baumeister, Tiago Maié, Sarah Schmitz, Anja Scheufen, Nathalie Brock, Steffen Koschmieder, Daniel Moreno-Andrés

Sci Rep. 2024; 14: 2810. Published online 2024 Feb 2. doi: 10.1038/s41598-024-53240-8

PMCID:: PMC10837458

Abstract Article PDF–3.9M

Select item 104472374.

Different niches for stem cells carrying the same oncogenic driver affect pathogenesis and therapy response in myeloproliferative neoplasms

Elodie Grockowiak, Claudia Korn, Justyna Rak, Veronika Lysenko, Adrien Hallou, Francesca M. Panvini, Matthew Williams, Claire Fielding, Zijian Fang, Eman Khatib-Massalha, Andrés García-García, Juan Li, Reema A. Khorshed, Sara González-Antón, E. Joanna Baxter, Anjali Kusumbe, Bridget S. Wilkins, Anna Green, Benjamin D. Simons, Claire N. Harrison, Anthony R. Green, Cristina Lo Celso, Alexandre P. A. Theocharides, Simón Méndez-Ferrer

Nat Cancer. 2023; 4(8): 1193–1209. Published online 2023 Aug 7. doi: 10.1038/s43018-023-00607-x

PMCID:: PMC10447237

Abstract Article PDF–18M

Select item 101658765.

The NK cell receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells

Sumit Sen Santara, Dian-Jang Lee, Ângela Crespo, Jun Jacob Hu, Caitlin Walker, Xiyu Ma, Ying Zhang, Sourav Chowdhury, Karla F. Meza-Sosa, Mercedes Lewandrowski, Haiwei Zhang, Marjorie Rowe, Arthur McClelland, Hao Wu, Caroline Junqueira, Judy Lieberman

Nature. Author manuscript; available in PMC 2023 May 8.

Published in final edited form as: Nature. 2023 Apr; 616(7956): 348–356. Published online 2023 Apr 5. doi: 10.1038/s41586-023-05912-0

Correction in:: Nature. 2023 May 17

PMCID:: PMC10165876

Abstract Article PDF–4.9M

Select item 96038606.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 95745157.

A STUB1 ubiquitin ligase/CHIC2 protein complex negatively regulates the IL-3, IL-5, and GM-CSF cytokine receptor common β chain (CSF2RB) protein stability

Sebastian H.J. Koochaki, Mikołaj Słabicki, Ryan Lumpkin, Charles Zou, Roger Belizaire, Eric S. Fischer, Benjamin L. Ebert

J Biol Chem. 2022 Oct; 298(10): 102484. Published online 2022 Sep 13. doi: 10.1016/j.jbc.2022.102484

PMCID:: PMC9574515

Abstract Article PDF–1.8M

Select item 94819338.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 93071689.

Social and maternal behavior in mesoderm specific transcript (Mest)-deficient mice

Rea P. Anunciado-Koza, J. Patrizia Stohn, Arturo Hernandez, Robert A. Koza

PLoS One. 2022; 17(7): e0271913. Published online 2022 Jul 22. doi: 10.1371/journal.pone.0271913

PMCID:: PMC9307168

Abstract Article PDF–1.8M

Select item 911781710.

Mannan-Binding Lectin via Interaction With Cell Surface Calreticulin Promotes Senescence of Activated Hepatic Stellate Cells to Limit Liver Fibrosis Progression

Jialiang Luo, Lei Li, Bo Chang, Zhengyumeng Zhu, Fan Deng, Mengyao Hu, Yu Yu, Xiao Lu, Zhengliang Chen, Daming Zuo, Jia Zhou

Cell Mol Gastroenterol Hepatol. 2022; 14(1): 75–99. Published online 2022 Apr 2. doi: 10.1016/j.jcmgh.2022.03.011

PMCID:: PMC9117817

Abstract Article PDF–13M

Select item 902551811.

Calreticulin Shortage Results in Disturbance of Calcium Storage, Mitochondrial Disease, and Kidney Injury

Asima Tayyeb, Gry H. Dihazi, Björn Tampe, Michael Zeisberg, Desiree Tampe, Samy Hakroush, Charlotte Bührig, Jenny Frese, Nazli Serin, Marwa Eltoweissy, Gerhard A. Müller, Hassan Dihazi

Cells. 2022 Apr; 11(8): 1329. Published online 2022 Apr 13. doi: 10.3390/cells11081329

PMCID:: PMC9025518

Abstract Article PDF–10M

Select item 899311912.

Mutation of SLC7A14 causes auditory neuropathy and retinitis pigmentosa mediated by lysosomal dysfunction

Kimberlee P. Giffen, Yi Li, Huizhan Liu, Xiao-Chang Zhao, Chang-Jun Zhang, Ren-Juan Shen, Tianying Wang, Amanda Janesick, Bo-Bei Chen, Shu-Sheng Gong, Bechara Kachar, Zi-Bing Jin, David Z. He

Sci Adv. 2022 Apr; 8(14): eabk0942. Published online 2022 Apr 8. doi: 10.1126/sciadv.abk0942

PMCID:: PMC8993119

Abstract Article PDF–6.6M

Select item 888237113.

Proteasomal degradation of the metabotropic glutamate receptor 1α is mediated by Homer-3 via the proteasomal S8 ATPase

Khosrow Rezvani, Kelli Baalman, Yanfen Teng, Maureen P. Mee, Simon P. Dawson, Hongmin Wang, Mariella De Biasi, R. John Mayer

J Neurochem. Author manuscript; available in PMC 2022 Feb 27.

Published in final edited form as: J Neurochem. 2012 Jul; 122(1): 24–37. Published online 2012 Apr 27. doi: 10.1111/j.1471-4159.2012.07752.x

PMCID:: PMC8882371

Abstract Article PDF–1.4M

Select item 821983514.

The ATF6β-calreticulin axis promotes neuronal survival under endoplasmic reticulum stress and excitotoxicity

Dinh Thi Nguyen, Thuong Manh Le, Tsuyoshi Hattori, Mika Takarada-Iemata, Hiroshi Ishii, Jureepon Roboon, Takashi Tamatani, Takayuki Kannon, Kazuyoshi Hosomichi, Atsushi Tajima, Shusuke Taniuchi, Masato Miyake, Seiichi Oyadomari, Takashi Tanaka, Nobuo Kato, Shunsuke Saito, Kazutoshi Mori, Osamu Hori

Sci Rep. 2021; 11: 13086. Published online 2021 Jun 22. doi: 10.1038/s41598-021-92529-w

PMCID:: PMC8219835

Abstract Article PDF–8.0M

Select item 819829115.

Calreticulin Deficiency Disturbs Ribosome Biogenesis and Results in Retardation in Embryonic Kidney Development

Nazli Serin, Gry H. Dihazi, Asima Tayyeb, Christof Lenz, Gerhard A. Müller, Michael Zeisberg, Hassan Dihazi

Int J Mol Sci. 2021 Jun; 22(11): 5858. Published online 2021 May 30. doi: 10.3390/ijms22115858

PMCID:: PMC8198291

Abstract Article PDF–6.8M

Select item 793877016.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 761431617.

STAT1 is essential for HSC function and maintains MHCII^hi stem cells that resist myeloablation and neoplastic expansion

Juan Li, Matthew J. Williams, Hyun Jung Park, Hugo P. Bastos, Xiaonan Wang, Daniel Prins, Nicola K. Wilson, Carys Johnson, Kendig Sham, Michelle Wantoch, Sam Watcham, Sarah J. Kinston, Dean C. Pask, Tina L. Hamilton, Rachel Sneade, Amie K. Waller, Cedric Ghevaert, George S. Vassiliou, Elisa Laurenti, David G. Kent, Berthold Göttgens, Anthony R. Green

Blood. 2022 Oct 6; 140(14): 1592–1606. Published online 2022 Jul 16. doi: 10.1182/blood.2021014009

PMCID:: PMC7614316

Abstract Article

Select item 752223318.

Calreticulin del52 and ins5 knock-in mice recapitulate different myeloproliferative phenotypes observed in patients with MPN

Camélia Benlabiod, Maira da Costa Cacemiro, Audrey Nédélec, Valérie Edmond, Delphine Muller, Philippe Rameau, Laure Touchard, Patrick Gonin, Stefan N. Constantinescu, Hana Raslova, Jean-Luc Villeval, William Vainchenker, Isabelle Plo, Caroline Marty

Nat Commun. 2020; 11: 4886. Published online 2020 Sep 28. doi: 10.1038/s41467-020-18691-3

PMCID:: PMC7522233

Abstract Article PDF–4.0M

Select item 741599119.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 734653920.

Endothelial calreticulin deletion impairs endothelial function in aged mice

Lauren A. Biwer, Henry R. Askew-Page, Kwangseok Hong, Jenna Milstein, Scott R. Johnstone, Edgar Macal, Miranda E. Good, Pooneh Bagher, Swapnil K. Sonkusare, Brant E. Isakson

Am J Physiol Heart Circ Physiol. 2020 May 1; 318(5): H1041–H1048. Published online 2020 Mar 20. doi: 10.1152/ajpheart.00586.2019

PMCID:: PMC7346539

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