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Select item 107212691.

A nerve-goblet cell association promotes allergic conjunctivitis through rapid antigen passage

Meiko Kimura, Tomoaki Ando, Yasuharu Kume, Saaya Fukase, Moe Matsuzawa, Kosuke Kashiwagi, Kumi Izawa, Ayako Kaitani, Nobuhiro Nakano, Keiko Maeda, Hideoki Ogawa, Ko Okumura, Shintaro Nakao, Akira Murakami, Nobuyuki Ebihara, Jiro Kitaura

JCI Insight. 2023 Nov 8; 8(21): e168596. Published online 2023 Nov 8. doi: 10.1172/jci.insight.168596

PMCID:: PMC10721269

Abstract Article PDF–2.5M

Select item 104322742.

Immune sensing of food allergens promotes avoidance behaviour

Esther B. Florsheim, Nathaniel D. Bachtel, Jaime L. Cullen, Bruna G. C. Lima, Mahdieh Godazgar, Fernando Carvalho, Carolina P. Chatain, Marcelo R. Zimmer, Cuiling Zhang, Gregory Gautier, Pierre Launay, Andrew Wang, Marcelo O. Dietrich, Ruslan Medzhitov

Nature. 2023; 620(7974): 643–650. Published online 2023 Jul 12. doi: 10.1038/s41586-023-06362-4

PMCID:: PMC10432274

Abstract Article PDF–7.0M

Select item 102696063.

A Co-Expressed Natural Antisense RNA FCER1A-AS Controls IgE-Dependent Immunity by Promoting Expression of FcεRIα

Ruo-yu Tang, Lan Yin, Liang Yao, Qing-Feng Zhang, Xiao-Ping Chen

Microbiol Spectr. 2023 May-Jun; 11(3): e00733-23. Published online 2023 May 8. doi: 10.1128/spectrum.00733-23

PMCID:: PMC10269606

Abstract Article PDF–2.1M

Select item 102523284.

IRF3 Activation in Mast Cells Promotes FcεRI-Mediated Allergic Inflammation

Young-Ae Choi, Hima Dhakal, Soyoung Lee, Namkyung Kim, Byungheon Lee, Taeg Kyu Kwon, Dongwoo Khang, Sang-Hyun Kim

Cells. 2023 Jun; 12(11): 1493. Published online 2023 May 28. doi: 10.3390/cells12111493

PMCID:: PMC10252328

Abstract Article PDF–2.9M

Select item 99934575.

Signals from the TAFA4-PTEN-PU.1 axis alleviate nasal allergy by modulating the expression of FcεRI in mast cells

Caijie Zhou, Meihua Li, Yu Liu, Xinxin Wang, Shuang Zhang, Li Guan, Jingyi Hong, Wei Zhou, Gaohui Wu, Weiliang Diao, Qinmiao Huang, Pingchang Yang

Clin Exp Immunol. 2023 Jan; 211(1): 15–22. Published online 2022 Nov 11. doi: 10.1093/cei/uxac097

PMCID:: PMC9993457

Abstract Article PDF–1.7M

Select item 82106116.

Elevated IgE promotes cardiac fibrosis by suppressing miR-486a-5p

Hongmei Zhao, Hongqin Yang, Chi Geng, Yang Chen, Yaqin Tang, Zhiwei Li, Junling Pang, Ting Shu, Yu Nie, Yongshuo Liu, Kegang Jia, Jing Wang

Theranostics. 2021; 11(15): 7600–7615. Published online 2021 Jun 5. doi: 10.7150/thno.47845

PMCID:: PMC8210611

Abstract Article PDF–3.9M

Select item 75728767.

IgE effector mechanisms, in concert with mast cells, contribute to acquired host defense against S. aureus

Philipp Starkl, Martin L. Watzenboeck, Lauren M. Popov, Sophie Zahalka, Anastasiya Hladik, Karin Lakovits, Mariem Radhouani, Arvand Haschemi, Thomas Marichal, Laurent L. Reber, Nicolas Gaudenzio, Riccardo Sibilano, Lukas Stulik, Frédéric Fontaine, André C. Mueller, Manuel R. Amieva, Stephen J. Galli, Sylvia Knapp

Immunity. Author manuscript; available in PMC 2021 Oct 13.

Published in final edited form as: Immunity. 2020 Oct 13; 53(4): 793–804.e9. Published online 2020 Sep 9. doi: 10.1016/j.immuni.2020.08.002

Correction in:: Immunity. 2020 Dec 15; 53(6): 1333.

PMCID:: PMC7572876

Abstract Article PDF–1.3M

Select item 75417228.

Mapping human monoclonal IgE epitopes on the major dust mite allergen Der p 2

Geoffrey A. Mueller, Jill Glesner, Jacob L. Daniel, Jian Zhang, Noah Hyduke, Crystal M. Richardson, Eugene F. DeRose, Martin D. Chapman, R. Stokes Peebles, Scott A. Smith, Anna Pomés

J Immunol. Author manuscript; available in PMC 2021 Oct 15.

Published in final edited form as: J Immunol. 2020 Oct 15; 205(8): 1999–2007. Published online 2020 Sep 9. doi: 10.4049/jimmunol.2000295

PMCID:: PMC7541722

Abstract Article PDF–2.3M

Select item 72071209.

Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection

Cedric Bosteels, Katrijn Neyt, Manon Vanheerswynghels, Mary J. van Helden, Dorine Sichien, Nincy Debeuf, Sofie De Prijck, Victor Bosteels, Niels Vandamme, Liesbet Martens, Yvan Saeys, Els Louagie, Manon Lesage, David L. Williams, Shiau-Choot Tang, Johannes U. Mayer, Franca Ronchese, Charlotte L. Scott, Hamida Hammad, Martin Guilliams, Bart N. Lambrecht

Immunity. 2020 Jun 16; 52(6): 1039–1056.e9. Published online 2020 May 8. doi: 10.1016/j.immuni.2020.04.005

PMCID:: PMC7207120

Abstract Article PDF–9.6M

Select item 695999510.

Inflammation-induced IgE promotes epithelial hyperplasia and tumour growth

Mark David Hayes, Sophie Ward, Greg Crawford, Rocio Castro Seoane, William David Jackson, David Kipling, David Voehringer, Deborah Dunn-Walters, Jessica Strid

eLife. 2020; 9: e51862. Published online 2020 Jan 14. doi: 10.7554/eLife.51862

PMCID:: PMC6959995

Abstract Article PDF–2.8M

Select item 694930311.

The mechanistic and functional profile of the therapeutic anti-IgE antibody ligelizumab differs from omalizumab

Pascal Gasser, Svetlana S. Tarchevskaya, Pascal Guntern, Daniel Brigger, Rahel Ruppli, Noemi Zbären, Silke Kleinboelting, Christoph Heusser, Theodore S. Jardetzky, Alexander Eggel

Nat Commun. 2020; 11: 165. Published online 2020 Jan 8. doi: 10.1038/s41467-019-13815-w

PMCID:: PMC6949303

Abstract Article PDF–4.4M

Select item 651683312.

IgE-mediated mast cell activation promotes inflammation and cartilage destruction in osteoarthritis

Qian Wang, Christin M Lepus, Harini Raghu, Laurent L Reber, Mindy M Tsai, Heidi H Wong, Ericka von Kaeppler, Nithya Lingampalli, Michelle S Bloom, Nick Hu, Eileen E Elliott, Francesca Oliviero, Leonardo Punzi, Nicholas J Giori, Stuart B Goodman, Constance R Chu, Jeremy Sokolove, Yoshihiro Fukuoka, Lawrence B Schwartz, Stephen J Galli, William H Robinson

eLife. 2019; 8: e39905. Published online 2019 May 14. doi: 10.7554/eLife.39905

PMCID:: PMC6516833

Abstract Article PDF–2.6M

Select item 640443313.

Role of ADTRP (Androgen‐Dependent Tissue Factor Pathway Inhibitor Regulating Protein) in Vascular Development and Function

Maulin M. Patel, Amanda R. Behar, Robert Silasi, Girija Regmi, Christopher L. Sansam, Ravi S. Keshari, Florea Lupu, Cristina Lupu

J Am Heart Assoc. 2018 Nov 20; 7(22): e010690. Published online 2018 Nov 14. doi: 10.1161/JAHA.118.010690

PMCID:: PMC6404433

Abstract Article PDF–6.5M

Select item 607186014.

Epithelial damage and tissue γδ T cells promote a unique tumor-protective IgE response

Greg Crawford, Mark David Hayes, Rocio Castro Seoane, Sophie Ward, Tim Dalessandri, Chester Lai, Eugene Healy, David Kipling, Charlotte Proby, Colin Moyes, Kile Green, Katie Best, Muzlifah Haniffa, Marina Botto, Deborah Dunn-Walters, Jessica Strid

Nat Immunol. Author manuscript; available in PMC 2019 Jan 16.

Published in final edited form as: Nat Immunol. 2018 Aug; 19(8): 859–870. Published online 2018 Jul 16. doi: 10.1038/s41590-018-0161-8

PMCID:: PMC6071860

Abstract Article PDF–2.7M

Select item 576541515.

House Dust Mite–Induced Allergic Airway Disease Is Independent of IgE and FcεRIα

Christopher G. McKnight, Joseph A. Jude, Zhenqi Zhu, Reynold A. Panettieri, Jr., Fred D. Finkelman

Am J Respir Cell Mol Biol. 2017 Dec; 57(6): 674–682. doi: 10.1165/rcmb.2016-0356OC

PMCID:: PMC5765415

Abstract Article PDF–854K

Select item 569817816.

Spontaneous food allergy in Was^−/− mice occurs independent of FcεRI-mediated mast cell activation

Willem S. Lexmond, Jeremy A. Goettel, Benjamin F. Sallis, Katelyn McCann, Edmond H. H. M. Rings, Erika Jensen-Jarolim, Samuel Nurko, Scott B. Snapper, Edda Fiebiger

Allergy. Author manuscript; available in PMC 2018 Dec 1.

Published in final edited form as: Allergy. 2017 Dec; 72(12): 1916–1924. Published online 2017 Jul 14. doi: 10.1111/all.13219

PMCID:: PMC5698178

Abstract Article PDF–533K

Select item 540084717.

Differences in the Importance of Mast Cells, Basophils, IgE, and IgG versus That of CD4⁺ T Cells and ILC2 Cells in Primary and Secondary Immunity to Strongyloides venezuelensis

Kaori Mukai, Hajime Karasuyama, Kenji Kabashima, Masato Kubo, Stephen J. Galli

Infect Immun. 2017 May; 85(5): e00053-17. Prepublished online 2017 Mar 6. Published online 2017 Apr 21. doi: 10.1128/IAI.00053-17

PMCID:: PMC5400847

Abstract Article PDF–2.6M

Select item 524126818.

Pathways of immediate hypothermia and leukocyte infiltration in an adjuvant-free mouse model of anaphylaxis

Bianca Balbino, Riccardo Sibilano, Philipp Starkl, Thomas Marichal, Nicolas Gaudenzio, Hajime Karasuyama, Pierre Bruhns, Mindy Tsai, Laurent L. Reber, Stephen J. Galli

J Allergy Clin Immunol. Author manuscript; available in PMC 2018 Feb 1.

Published in final edited form as: J Allergy Clin Immunol. 2017 Feb; 139(2): 584–596.e10. Published online 2016 Jul 17. doi: 10.1016/j.jaci.2016.05.047

PMCID:: PMC5241268

Abstract Article PDF–3.1M

Select item 488521919.

Murine allergic rhinitis and nasal T_h2 activation are mediated via TSLP- and IL-33-signaling pathways

Shoko Akasaki, Kazufumi Matsushita, Yukinori Kato, Ayumi Fukuoka, Naruhito Iwasaki, Masakiyo Nakahira, Shigeharu Fujieda, Koubun Yasuda, Tomohiro Yoshimoto

Int Immunol. 2016 Feb; 28(2): 65–76. Published online 2015 Oct 1. doi: 10.1093/intimm/dxv055

PMCID:: PMC4885219

Abstract Article

Select item 487125320.

Tetraspanin CD151 Is a Negative Regulator of FcεRI-Mediated Mast Cell Activation

Hiam Abdala-Valencia, Paul J. Bryce, Robert P. Schleimer, Joshua B. Wechsler, Lucas F. Loffredo, Joan M. Cook-Mills, Chia-Lin Hsu, Sergejs Berdnikovs

J Immunol. Author manuscript; available in PMC 2016 May 18.

Published in final edited form as: J Immunol. 2015 Aug 15; 195(4): 1377–1387. Published online 2015 Jul 1. doi: 10.4049/jimmunol.1302874

PMCID:: PMC4871253

Abstract Article PDF–808K

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