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Select item 111765771.

Trefoil factor 1 suppresses stemness and enhances chemosensitivity of pancreatic cancer

Junpei Yamaguchi, Toshio Kokuryo, Yukihiro Yokoyama, Shunsuke Oishi, Masaki Sunagawa, Takashi Mizuno, Shunsuke Onoe, Nobuyuki Watanabe, Atsushi Ogura, Tomoki Ebata

Cancer Med. 2024 Jun; 13(11): e7395. Published online 2024 Jun 13. doi: 10.1002/cam4.7395

PMCID:: PMC11176577

Abstract Article PDF–17M

Select item 111383792.

Trefoil factors: Pleiotropic effects of Trefoil Factor 1 deficiency

C. Tomasetto, M.-C. Rio

Cell Mol Life Sci. 2005 Dec; 62(24): 2916–2920. Published online 2005 Dec 5. doi: 10.1007/s00018-005-5479-3

PMCID:: PMC11138379

Abstract PDF–109K

Select item 109176603.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 104543314.

Expression Profiling along the Murine Intestine: Different Mucosal Protection Systems and Alterations in Tff1-Deficient Animals

Franz Salm, Eva B. Znalesniak, Aikaterini Laskou, Sönke Harder, Hartmut Schlüter, Werner Hoffmann

Int J Mol Sci. 2023 Aug; 24(16): 12684. Published online 2023 Aug 11. doi: 10.3390/ijms241612684

PMCID:: PMC10454331

Abstract Article PDF–3.4M

Select item 99251165.

TFF2 deficiency exacerbates weight loss and alters immune cell and cytokine profiles in DSS colitis, and this cannot be rescued by wild-type bone marrow

Louise M. Judd, Heather V. Chalinor, Anna Walduck, Daniel I. Pavlic, Jan Däbritz, Zinaida Dubeykovskaya, Timothy C. Wang, Trevelyan R. Menheniott, Andrew S. Giraud

Am J Physiol Gastrointest Liver Physiol. 2015 Jan 1; 308(1): G12–G24. Published online 2014 Oct 16. doi: 10.1152/ajpgi.00172.2014

PMCID:: PMC9925116

Abstract Article

Select item 96291356.

Induction of Fibroblast Growth Factor Receptor 4 by Helicobacter pylori via Signal Transducer and Activator of Transcription 3 With a Feedforward Activation Loop Involving Steroid Receptor Coactivator Signaling in Gastric Cancer

Xing Zhang, Mohammed Soutto, Zheng Chen, Nadeem Bhat, Shoumin Zhu, Moritz F. Eissmann, Matthias Ernst, Heng Lu, Dunfa Peng, Zekuan Xu, Wael El-Rifai

Gastroenterology. Author manuscript; available in PMC 2023 Sep 1.

Published in final edited form as: Gastroenterology. 2022 Sep; 163(3): 620–636.e9. Published online 2022 May 17. doi: 10.1053/j.gastro.2022.05.016

PMCID:: PMC9629135

Abstract Article PDF–3.3M

Select item 91592707.

IL-33 promotes gastric tumour growth in concert with activation and recruitment of inflammatory myeloid cells

Chau P. Tran, Michelle Scurr, Louise O’Connor, Jon N. Buzzelli, Garrett Z. Ng, Sharleen Chung Nien Chin, Lincon A. Stamp, Toshinari Minamoto, Andrew S. Giraud, Louise M. Judd, Philip Sutton, Trevelyan R. Menheniott

Oncotarget. 2022; 13: 785–799. Published online 2022 Jun 1. doi: 10.18632/oncotarget.28238

PMCID:: PMC9159270

Abstract Article PDF–7.5M

Select item 89485808.

Aorta Regulatory T Cells with a Tissue‐Specific Phenotype and Function Promote Tissue Repair through Tff1 in Abdominal Aortic Aneurysms

Jingyong Li, Ni Xia, Dan Li, Shuang Wen, Shirui Qian, Yuzhi Lu, Muyang Gu, Tingting Tang, Jiao Jiao, Bingjie Lv, Shaofang Nie, Desheng Hu, Yuhua Liao, Xiangping Yang, Guoping Shi, Xiang Cheng

Adv Sci (Weinh) 2022 Mar; 9(9): 2104338. Published online 2022 Jan 24. doi: 10.1002/advs.202104338

PMCID:: PMC8948580

Abstract Article PDF–5.8M

Select item 73590969.

Nuclear MYH9-induced CTNNB1 transcription, targeted by staurosporin, promotes gastric cancer cell anoikis resistance and metastasis

Gengtai Ye, Qingbin Yang, Xuetao Lei, Xianjun Zhu, Fengping Li, Jiayong He, Hao Chen, Ruoyu Ling, Haisheng Zhang, Tian Lin, Zhiping Liang, Yanrui Liang, Haipeng Huang, Weihong Guo, Haijun Deng, Hao Liu, Yanfeng Hu, Jiang Yu, Guoxin Li

Theranostics. 2020; 10(17): 7545–7560. Published online 2020 Jun 12. doi: 10.7150/thno.46001

PMCID:: PMC7359096

Abstract Article PDF–3.7M

Select item 701420310.

Molecular Alterations in the Stomach of Tff1-Deficient Mice: Early Steps in Antral Carcinogenesis

Eva B. Znalesniak, Franz Salm, Werner Hoffmann

Int J Mol Sci. 2020 Jan; 21(2): 644. Published online 2020 Jan 18. doi: 10.3390/ijms21020644

PMCID:: PMC7014203

Abstract Article PDF–1.9M

Select item 672876611.

Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production

Julie Piccand, Constance Vagne, Florence Blot, Aline Meunier, Anthony Beucher, Perrine Strasser, Mari L. Lund, Sabitri Ghimire, Laure Nivlet, Céline Lapp, Natalia Petersen, Maja S. Engelstoft, Christelle Thibault-Carpentier, Céline Keime, Sara Jimenez Correa, Valérie Schreiber, Nacho Molina, Thue W. Schwartz, Adèle De Arcangelis, Gérard Gradwohl

Mol Metab. 2019 Nov; 29: 24–39. Published online 2019 Aug 13. doi: 10.1016/j.molmet.2019.08.007

PMCID:: PMC6728766

Abstract Article PDF–3.3M

Select item 663915712.

Activation of IGF1R by DARPP-32 promotes STAT3 signaling in gastric cancer cells

Shoumin Zhu, Mohammed Soutto, Zheng Chen, M. Blanca Piazuelo, M. Kay Washington, Abbes Belkhiri, Alexander Zaika, Dunfa Peng, Wael El-Rifai

Oncogene. Author manuscript; available in PMC 2019 Dec 24.

Published in final edited form as: Oncogene. 2019 Jul; 38(29): 5805–5816. Published online 2019 Jun 24. doi: 10.1038/s41388-019-0843-1

Correction in:: Oncogene. 2023 Dec 11

PMCID:: PMC6639157

Abstract Article PDF–2.7M

Select item 662028213.

Activation of STAT3 signaling is mediated by TFF1 silencing in gastric neoplasia

Mohammed Soutto, Zheng Chen, Ajaz A. Bhat, Lihong Wang, Shoumin Zhu, Ahmed Gomaa, Andreia Bates, Nadeem S. Bhat, Dunfa Peng, Abbes Belkhiri, M. Blanca Piazuelo, M. Kay Washington, Xi Chen Steven, Richard Peek, Jr., Wael El-Rifai

Nat Commun. 2019; 10: 3039. Published online 2019 Jul 10. doi: 10.1038/s41467-019-11011-4

PMCID:: PMC6620282

Abstract Article PDF–4.1M

Select item 649623314.

Amplification and invasiveness of epithelial progenitors during gastric carcinogenesis in trefoil factor 1 knockout mice

S. M. Karam, C. Tomasetto, M.‐C. Rio

Cell Prolif. 2008 Dec; 41(6): 923–935. Published online 2008 Nov 18. doi: 10.1111/j.1365-2184.2008.00562.x

PMCID:: PMC6496233

Abstract Article PDF–3.1M

Select item 645951015.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Abstract Article PDF–5.1M

Select item 635505916.

Helicobacter pylori-induced miR-135b-5p promotes cisplatin resistance in gastric cancer

Linlin Shao, Zheng Chen, Mohammed Soutto, Shoumin Zhu, Heng Lu, Judith Romero-Gallo, Richard Peek, Shutian Zhang, Wael El-Rifai

FASEB J. 2019 Jan; 33(1): 264–274. Published online 2018 Jul 9. doi: 10.1096/fj.201701456RR

PMCID:: PMC6355059

Abstract Article

Select item 633360217.

Disruption of the Tff1 gene in mice using CRISPR/Cas9 promotes body weight reduction and gastric tumorigenesis

Hyejeong Kim, Haengdueng Jeong, Yejin Cho, Jaehoon Lee, Ki Taek Nam, Han-Woong Lee

Lab Anim Res. 2018 Dec; 34(4): 257–263. Published online 2018 Dec 31. doi: 10.5625/lar.2018.34.4.257

PMCID:: PMC6333602

Abstract Article PDF–7.0M

Select item 606350218.

Trefoil factor 1 inhibits epithelial-mesenchymal transition of pancreatic intraepithelial neoplasm

Junpei Yamaguchi, Yukihiro Yokoyama, Toshio Kokuryo, Tomoki Ebata, Atsushi Enomoto, Masato Nagino

J Clin Invest. 2018 Aug 1; 128(8): 3619–3629. Published online 2018 Jul 23. doi: 10.1172/JCI97755

PMCID:: PMC6063502

Abstract Article PDF–24M

Select item 588250119.

HOXA10 Promoter Methylation Directs miR-196b-5p-dependent Cell Proliferation and Invasion in Gastric Cancer

Linlin Shao, Zheng Chen, Dunfa Peng, Mohammed Soutto, Shoumin Zhu, Andreia Bates, Shutian Zhang, Wael El-Rifai

Mol Cancer Res. Author manuscript; available in PMC 2018 Oct 1.

Published in final edited form as: Mol Cancer Res. 2018 Apr; 16(4): 696–706. Published online 2018 Feb 16. doi: 10.1158/1541-7786.MCR-17-0655

PMCID:: PMC5882501

Abstract Article PDF–878K

Select item 564919020.

Gastric TFF1 Expression from Acute to Chronic Helicobacter Infection

Roberta Esposito, Silvana Morello, Megi Vllahu, Daniela Eletto, Amalia Porta, Alessandra Tosco

Front Cell Infect Microbiol. 2017; 7: 434. Published online 2017 Oct 9. doi: 10.3389/fcimb.2017.00434

PMCID:: PMC5649190

Abstract Article PDF–2.4M

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