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Items: 1 to 20 of 480

1.
Crosstalk of MAP3K1 and EGFR signaling mediates gene-environment interactions that block developmental tissue closure
Jingjing Wang, Bo Xiao, Eiki Kimura, Maureen Mongan, Wei-Wen Hsu, Mario Medvedovic, Alvaro Puga, Ying Xia
J Biol Chem. 2024 Jul; 300(7): 107486. Published online 2024 Jun 18. doi: 10.1016/j.jbc.2024.107486
PMCID:
PMC11294703
AbstractArticlePDF–3.6M
2.
A fibronectin gradient remodels mixed-phase mesoderm
Min Zhu, Bin Gu, Evan C. Thomas, Yunyun Huang, Yun-Kyo Kim, Hirotaka Tao, Theodora M. Yung, Xin Chen, Kaiwen Zhang, Elizabeth K. Woolaver, Mikaela R. Nevin, Xi Huang, Rudolph Winklbauer, Janet Rossant, Yu Sun, Sevan Hopyan
Sci Adv. 2024 Jul 19; 10(29): eadl6366. Published online 2024 Jul 19. doi: 10.1126/sciadv.adl6366
PMCID:
PMC11259159
AbstractArticlePDF–6.7M
3.
Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice
Yi Lv, Qian Wang, Chensheng Lin, Xi Zheng, Yanding Zhang, Xuefeng Hu
Front Cell Dev Biol. 2024; 12: 1376814. Published online 2024 Apr 17. doi: 10.3389/fcell.2024.1376814
PMCID:
PMC11061347
AbstractArticlePDF–11M
4.
A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis
Jingwen Yang, Lingxin Zhu, Haichun Pan, Hiroki Ueharu, Masako Toda, Qian Yang, Shawn A. Hallett, Lorin E. Olson, Yuji Mishina
J Clin Invest. 2024 Apr 15; 134(8): e165787. Published online 2024 Mar 11. doi: 10.1172/JCI165787
PMCID:
PMC11014657
AbstractArticlePDF–16M
5.
MAP3K1 regulates female reproductive tract development
Eiki Kimura, Maureen Mongan, Bo Xiao, Antonius Christianto, Jingjing Wang, Vinicius S. Carreira, Brad Bolon, Xiang Zhang, Katherine A. Burns, Jacek Biesiada, Mario Medvedovic, Alvaro Puga, Ying Xia
Dis Model Mech. 2024 Mar 1; 17(3): dmm050669. Published online 2024 Mar 28. doi: 10.1242/dmm.050669
PMCID:
PMC10985838
AbstractArticle
6.
Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy
Yan Guo, Pan Xiang, Xiaojiao Sun, Wei Liu, Jiafeng Zhou, Bin Yin, Lin Hou, Boqin Qiang, Huiliang Li, Pengcheng Shu, Xiaozhong Peng
Signal Transduct Target Ther. 2024; 9: 32. Published online 2024 Feb 14. doi: 10.1038/s41392-024-01742-2
PMCID:
PMC10864363
AbstractArticlePDF–9.9M
7.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
8.
Physical exercise elicits UPRmt in the skeletal muscle: The role of c-Jun N-terminal kinase
Rodrigo Stellzer Gaspar, Carlos Kiyoshi Katashima, Barbara Moreira Crisol, Fernanda Silva Carneiro, Igor Sampaio, Leonardo dos Reis Silveira, Adelino Sanchez Ramos da Silva, Dennys Esper Cintra, José Rodrigo Pauli, Eduardo Rochete Ropelle
Mol Metab. 2023 Dec; 78: 101816. Published online 2023 Oct 10. doi: 10.1016/j.molmet.2023.101816
PMCID:
PMC10590869
AbstractArticlePDF–3.3M
9.
A non-translational role of threonyl-tRNA synthetase in regulating JNK signaling during myogenic differentiation
Chong Dai, Adriana Reyes-Ordoñez, Jae-Sung You, Jie Chen
FASEB J. Author manuscript; available in PMC 2023 May 29.
Published in final edited form as: FASEB J. 2021 Oct; 35(10): e21948. doi: 10.1096/fj.202101094R
PMCID:
PMC10226677
AbstractArticlePDF–1.9M
10.
Hypothalamic JNK1-hepatic fatty acid synthase axis mediates a metabolic rewiring that prevents hepatic steatosis in male mice treated with olanzapine via intraperitoneal: Additional effects of PTP1B inhibition
Vitor Ferreira, Cintia Folgueira, María García-Altares, Maria Guillén, Mónica Ruíz-Rosario, Giada DiNunzio, Irma Garcia-Martinez, Rosa Alen, Christoph Bookmeyer, John G. Jones, Juan C. Cigudosa, Pilar López-Larrubia, Xavier Correig-Blanchar, Roger J. Davis, Guadalupe Sabio, Patricia Rada, Ángela M. Valverde
Redox Biol. 2023 Jul; 63: 102741. Published online 2023 May 15. doi: 10.1016/j.redox.2023.102741
PMCID:
PMC10225935
AbstractArticlePDF–18M
11.
Transmembrane p24 trafficking protein 10 (TMED10) inhibits mitochondrial damage and protects neurons in ischemic stroke via the c-Jun N-terminal kinase (JNK) signaling pathway
Qiushi Li, Xuying Liu, Ruixian Xing, Rubo Sui
Exp Anim. 2023; 72(2): 151–163. Published online 2022 Oct 14. doi: 10.1538/expanim.22-0060
PMCID:
PMC10202712
AbstractArticlePDF–4.5M
12.
Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise
Kenta Kuramoto, Huijia Liang, Jung-Hwa Hong, Congcong He
Cell Metab. Author manuscript; available in PMC 2024 Apr 4.
Published in final edited form as: Cell Metab. 2023 Apr 4; 35(4): 620–632.e5. Published online 2023 Feb 21. doi: 10.1016/j.cmet.2023.01.011
PMCID:
PMC10079584
AbstractArticlePDF–2.5M
13.
HER2-driven breast cancer suppression by the JNK signaling pathway
Zeynep Itah, Shanzah Chaudhry, Sithara Raju Ponny, Ozkan Aydemir, Alexandra Lee, Julie Cavanagh-Kyros, Cathy Tournier, William J. Muller, Roger J. Davis
Proc Natl Acad Sci U S A. 2023 Jan 24; 120(4): e2218373120. Published online 2023 Jan 19. doi: 10.1073/pnas.2218373120
PMCID:
PMC9942916
AbstractArticlePDF–5.9M
14.
Phosphorylation of RXRα mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome
Santiago Vernia, Alexandra Lee, Norman J. Kennedy, Myoung Sook Han, Marta Isasa, Julie Cavanagh-Kyros, Armanda Roy, Aafreen Syed, Shanzah Chaudhry, Yvonne J. K. Edwards, Steven P. Gygi, Guangping Gao, Roger J. Davis
Proc Natl Acad Sci U S A. 2022 Nov 1; 119(44): e2210434119. Published online 2022 Oct 25. doi: 10.1073/pnas.2210434119
PMCID:
PMC9636906
AbstractArticlePDF–1.7M
15.
Bmp7 drives proximal tubule expansion and determines nephron number in the developing kidney
Mary Taglienti, Daniel Graf, Valerie Schumacher, Jordan A. Kreidberg
Development. 2022 Jul 15; 149(14): dev200773. Published online 2022 Jul 25. doi: 10.1242/dev.200773
PMCID:
PMC9382899
AbstractArticle
16.
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) safeguards the developing mouse cortex
Tamar Sapir, Aditya Kshirsagar, Anna Gorelik, Tsviya Olender, Ziv Porat, Ingrid E. Scheffer, David B. Goldstein, Orrin Devinsky, Orly Reiner
Nat Commun. 2022; 13: 4209. Published online 2022 Jul 21. doi: 10.1038/s41467-022-31752-z
PMCID:
PMC9304408
AbstractArticlePDF–13M
17.
EpCAM Is Essential to Maintaining the Immune Homeostasis of Intestines via Keeping the Expression of pIgR in the Intestinal Epithelium of Mice
Zili Lei, Wanwan Liu, Ya Nie, Yanhong Yang, Guibin Chen, Li Huang, Huijuan Wu, Yuting Lei, Lei Chen, Qing Hu, Hedong Rong, Siping Yu, Qi Song, Fengxue Tong, Jiao Guo
Front Immunol. 2022; 13: 843378. Published online 2022 Apr 13. doi: 10.3389/fimmu.2022.843378
PMCID:
PMC9043958
AbstractArticlePDF–8.1M
18.
Inactivating Celsr2 promotes motor axon fasciculation and regeneration in mouse and human
Quan Wen, Huandi Weng, Tao Liu, Lingtai Yu, Tianyun Zhao, Jingwen Qin, Si Li, Qingfeng Wu, Fadel Tissir, Yibo Qu, Libing Zhou
Brain. 2022 Feb; 145(2): 670–683. Published online 2022 Jan 4. doi: 10.1093/brain/awab317
PMCID:
PMC9014747
AbstractArticlePDF–2.3M
19.
Early construction of the thalamocortical axon pathway requires c-Jun N-terminal kinase signaling within the ventral forebrain
Jessica G. Cunningham, James D. Scripter, Stephany A. Nti, Eric S. Tucker
Dev Dyn. Author manuscript; available in PMC 2023 Mar 1.
Published in final edited form as: Dev Dyn. 2022 Mar; 251(3): 459–480. Published online 2021 Sep 18. doi: 10.1002/dvdy.416
PMCID:
PMC8891049
AbstractArticlePDF–2.5M
20.
miR-221-5p-Mediated Downregulation of JNK2 Aggravates Acute Lung Injury
Jing Yang, Hanh Chi Do-Umehara, Qiao Zhang, Huashan Wang, Changchun Hou, Huali Dong, Edith A. Perez, Marc A. Sala, Kishore R. Anekalla, James M. Walter, Shuwen Liu, Richard G. Wunderink, G.R. Scott Budinger, Jing Liu
Front Immunol. 2021; 12: 700933. Published online 2021 Nov 25. doi: 10.3389/fimmu.2021.700933
PMCID:
PMC8656235
AbstractArticlePDF–5.8M

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