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Select item 107597191.

Identification and validation of voltage‐dependent anion channel 1‐related genes and immune cell infiltration in diabetic nephropathy

Jiaqun Lin, Mengjie Weng, Jing Zheng, Kun Nie, Siyi Rao, Yongjie Zhuo, Jianxin Wan

J Diabetes Investig. 2024 Jan; 15(1): 87–105. Published online 2023 Sep 22. doi: 10.1111/jdi.14087

PMCID:: PMC10759719

Abstract Article PDF–11M

Select item 106176732.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 105658763.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 105140814.

HSP90 C-terminal domain inhibition promotes VDAC1 oligomerization via decreasing K274 mono-ubiquitination in Hepatocellular Carcinoma

Jinxin Zhang, Lixia Liu, Yan Li, Yaling Huang, Senbo Xiao, Zihao Deng, Zhenming Zheng, Jieyou Li, Manfeng Liang, Guantai Xie, Xiao Chen, Yaotang Deng, Wenchong Tan, Hairou Su, Guibing Wu, Chunqing Cai, Xuemei Chen, Fei Zou

Neoplasia. 2023 Oct; 44: 100935. Published online 2023 Sep 15. doi: 10.1016/j.neo.2023.100935

PMCID:: PMC10514081

Abstract Article PDF–14M

Select item 103927325.

Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1

Ying Liu, Hanwen Zhang, Yiwei Liu, Siyue Zhang, Peng Su, Lijuan Wang, Yaming Li, Yiran Liang, Xiaolong Wang, Weijing Zhao, Bing Chen, Dan Luo, Ning Zhang, Qifeng Yang

Autophagy. 2023; 19(9): 2443–2463. Published online 2023 Mar 1. doi: 10.1080/15548627.2023.2182482

PMCID:: PMC10392732

Abstract Article PDF–10M

Select item 103083656.

A mitochondrial SCF‐FBXL4 ubiquitin E3 ligase complex degrades BNIP3 and NIX to restrain mitophagy and prevent mitochondrial disease

Yu Cao, Jing Zheng, Huayun Wan, Yuqiu Sun, Song Fu, Shanshan Liu, Baiyu He, Gaihong Cai, Yang Cao, Huanwei Huang, Qi Li, Yan Ma, She Chen, Fengchao Wang, Hui Jiang

EMBO J. 2023 Jul; 42(13): e113033. Published online 2023 Mar 10. doi: 10.15252/embj.2022113033

PMCID:: PMC10308365

Abstract Article PDF–5.2M

Select item 102841177.

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry

Fenglong Jiao, Leah J. Salituro, Clinton Yu, Craig B. Gutierrez, Scott D. Rychnovsky, Lan Huang

Anal Chem. Author manuscript; available in PMC 2023 Jun 21.

Published in final edited form as: Anal Chem. 2023 Jan 31; 95(4): 2532–2539. Published online 2023 Jan 18. doi: 10.1021/acs.analchem.2c04986

PMCID:: PMC10284117

Abstract Article PDF–2.5M

Select item 102567868.

HNF4A-BAP31-VDAC1 axis synchronously regulates cell proliferation and ferroptosis in gastric cancer

Qingqing Zhou, Tengfei Liu, Wenjing Qian, Jun Ji, Qu Cai, Yangbing Jin, Jinling Jiang, Jun Zhang

Cell Death Dis. 2023 Jun; 14(6): 356. Published online 2023 Jun 9. doi: 10.1038/s41419-023-05868-z

PMCID:: PMC10256786

Abstract Article PDF–7.6M

Select item 102433989.

Evolution of Mycobacterium abscessus in the human lung: Cumulative mutations and genomic rearrangement of porin genes in patient isolates

Shamira J. Shallom, Hervé Tettelin, Prabha Chandrasekaran, In Kwon Park, Sonia Agrawal, Kriti Arora, Lisa Sadzewicz, Aaron M. Milstone, Moira L. Aitken, Barbara A. Brown-Elliott, Richard J. Wallace, Jr, Elizabeth P. Sampaio, Michael Niederweis, Kenneth N. Olivier, Steven M. Holland, Adrian M. Zelazny

Virulence. 2023; 14(1): 2215602. Published online 2023 Jun 4. doi: 10.1080/21505594.2023.2215602

PMCID:: PMC10243398

Abstract Article PDF–1.8M

Select item 1023742210.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1013893111.

Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage

Sanna Abbasi, Laila Bayat, Caroline Schild-Poulter

Int J Mol Sci. 2023 Apr; 24(8): 7041. Published online 2023 Apr 11. doi: 10.3390/ijms24087041

PMCID:: PMC10138931

Abstract Article PDF–4.0M

Select item 1004641712.

Ablation of GPR56 Causes β-Cell Dysfunction by ATP Loss through Mistargeting of Mitochondrial VDAC1 to the Plasma Membrane

Israa Mohammad Al-Amily, Marie Sjögren, Pontus Duner, Mohammad Tariq, Claes B. Wollheim, Albert Salehi

Biomolecules. 2023 Mar; 13(3): 557. Published online 2023 Mar 18. doi: 10.3390/biom13030557

PMCID:: PMC10046417

Abstract Article PDF–2.9M

Select item 997294513.

Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2

Xinxin Wang, Zhiyuan Wen, Huizhen Cao, Jie Luo, Lei Shuai, Chong Wang, Jinying Ge, Xijun Wang, Zhigao Bu, Jinliang Wang

J Virol. 2023 Feb; 97(2): e01611-22. Published online 2023 Feb 13. doi: 10.1128/jvi.01611-22

PMCID:: PMC9972945

Abstract Article PDF–3.0M

Select item 997032014.

miRNA-874-3p inhibits the migration, invasion and proliferation of breast cancer cells by targeting VDAC1

Housheng Yang, Zhiwen Wang, Shuang Hu, Lu Chen, Wei Li, Zhongyi Yang

Aging (Albany NY) 2023 Feb 14; 15(3): 705–717. Published online 2023 Jan 10. doi: 10.18632/aging.204474

PMCID:: PMC9970320

Abstract Article PDF–1.9M

Select item 996341515.

VDAC1 Knockout Affects Mitochondrial Oxygen Consumption Triggering a Rearrangement of ETC by Impacting on Complex I Activity

Andrea Magrì, Salvatore Antonio Maria Cubisino, Giuseppe Battiato, Cristiana Lucia Rita Lipari, Stefano Conti Nibali, Miriam Wissam Saab, Alessandra Pittalà, Angela Maria Amorini, Vito De Pinto, Angela Messina

Int J Mol Sci. 2023 Feb; 24(4): 3687. Published online 2023 Feb 12. doi: 10.3390/ijms24043687

PMCID:: PMC9963415

Abstract Article PDF–2.6M

Select item 995044716.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 989825217.

Site-specific ubiquitination of VDAC1 restricts its oligomerization and mitochondrial DNA release in liver fibrosis

Ne N. Wu, Lifeng Wang, Lu Wang, Xihui Xu, Gary D. Lopaschuk, Yingmei Zhang, Jun Ren

Exp Mol Med. 2023 Jan; 55(1): 269–280. Published online 2023 Jan 19. doi: 10.1038/s12276-022-00923-9

PMCID:: PMC9898252

Abstract Article PDF–5.9M

Select item 986049618.

Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid–liquid phase separation–based method

Ryota Hayashida, Reika Kikuchi, Kenichiro Imai, Waka Kojima, Tatsuya Yamada, Miho Iijima, Hiromi Sesaki, Keiji Tanaka, Noriyuki Matsuda, Koji Yamano

J Biol Chem. 2023 Feb; 299(2): 102822. Published online 2022 Dec 21. doi: 10.1016/j.jbc.2022.102822

PMCID:: PMC9860496

Abstract Article PDF–6.6M

Select item 985197319.

A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets

Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I. Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, Savaş Tay, Glenn Randall, Peihui Wang, John T. Lis, Cédric Feschotte, Serpil C. Erzurum, Feixiong Cheng, Haiyuan Yu

Nat Biotechnol. Author manuscript; available in PMC 2023 Jan 20.

Published in final edited form as: Nat Biotechnol. 2023 Jan; 41(1): 128–139. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01474-0

PMCID:: PMC9851973

Abstract Article PDF–4.0M

Select item 981605920.

CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1

Dongbao Li, Yuhong Wang, Chao Dong, Tao Chen, Anqi Dong, Jiayu Ren, Weikang Li, Gege Shu, Jiaoyang Yang, Wenhao Shen, Lei Qin, Lin Hu, Jin Zhou

Oncogene. 2023; 42(2): 83–98. Published online 2022 Nov 12. doi: 10.1038/s41388-022-02537-x

PMCID:: PMC9816059

Abstract Article PDF–7.6M

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