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Items: 1 to 20 of 23

1.
Glycerol 3-phosphate dehydrogenases (1 and 2) in cancer and other diseases
Sehyun Oh, Xuan Linh Mai, Jiwoo Kim, Arvie Camille V. de Guzman, Ji Yun Lee, Sunghyouk Park
Exp Mol Med. 2024 May; 56(5): 1066–1079. Published online 2024 May 1. doi: 10.1038/s12276-024-01222-1
PMCID:
PMC11148179
AbstractArticlePDF–1.4M
2.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
3.
Non-bioenergetic roles of mitochondrial GPD2 promote tumor progression
Sehyun Oh, Sihyang Jo, Martina Bajzikova, Han Sun Kim, Thien T. P. Dao, Jakub Rohlena, Jin-Mo Kim, Jiri Neuzil, Sunghyouk Park
Theranostics. 2023; 13(2): 438–457. Published online 2023 Jan 1. doi: 10.7150/thno.75973
PMCID:
PMC9830446
AbstractArticlePDF–5.9M
4.
A HIF1α-GPD1 feedforward loop inhibits the progression of renal clear cell carcinoma via mitochondrial function and lipid metabolism
Ren Liu, Yuanfa Feng, Yulin Deng, Zhihao Zou, Jianheng Ye, Zhiduan Cai, Xuejin Zhu, Yingke Liang, Jianming Lu, Hui Zhang, Yong Luo, Zhaodong Han, Yangjia Zhuo, Qingling Xie, Chi Tin Hon, Yuxiang Liang, Chin-Lee Wu, Weide Zhong
J Exp Clin Cancer Res. 2021; 40: 188. Published online 2021 Jun 7. doi: 10.1186/s13046-021-01996-6
PMCID:
PMC8185942
AbstractArticlePDF–7.4M
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
The Organization of Active Site Side Chains of Glycerol-3-phosphate Dehydrogenase Promotes Efficient Enzyme Catalysis and Rescue of Variant Enzymes
Judith R. Cristobal, Archie C. Reyes, John P. Richard
Biochemistry. 2020 Apr 28; 59(16): 1582–1591. Published online 2020 Apr 6. doi: 10.1021/acs.biochem.0c00175
PMCID:
PMC7207223
AbstractArticlePDF–3.3M
7.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
8.
Comparative Proteome Analysis of Breast Cancer Tissues Highlights the Importance of Glycerol-3- phosphate Dehydrogenase 1 and Monoacylglycerol Lipase in Breast Cancer Metabolism
KUBRA KARAOSMANOGLU YONETEN, MURAT KASAP, GURLER AKPINAR, ABDULLAH GUNES, BORA GUREL, NIHAT ZAFER UTKAN
Cancer Genomics Proteomics. 2019 Sep-Oct; 16(5): 377–397. Published online 2019 Sep 3. doi: 10.21873/cgp.20143
PMCID:
PMC6727073
AbstractArticlePDF–1.0M
9.
Primary Deuterium Kinetic Isotope Effects: A Probe for the Origin of the Rate Acceleration for Hydride Transfer Catalyzed by Glycerol-3-Phosphate Dehydrogenase
Archie C. Reyes, Tina L. Amyes, John P. Richard
Biochemistry. 2018 Jul 24; 57(29): 4338–4348. Published online 2018 Jun 21. doi: 10.1021/acs.biochem.8b00536
PMCID:
PMC6091503
AbstractArticlePDF–1.7M
10.
High-throughput analysis of the RNA-induced silencing complex in myotonic dystrophy type 1 patients identifies the dysregulation of miR-29c and its target ASB2
Marisa Cappella, Alessandra Perfetti, Beatrice Cardinali, Jose Manuel Garcia-Manteiga, Matteo Carrara, Claudia Provenzano, Paola Fuschi, Rosanna Cardani, Laura Valentina Renna, Giovanni Meola, Germana Falcone, Fabio Martelli
Cell Death Dis. 2018 Jul; 9(7): 729. Published online 2018 Jun 28. doi: 10.1038/s41419-018-0769-5
PMCID:
PMC6023919
AbstractArticlePDF–1.2M
11.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
12.
Panorama of ancient metazoan macromolecular complexes
Cuihong Wan, Blake Borgeson, Sadhna Phanse, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Berzginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, Brent Derry, Elisabeth Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili
Nature. Author manuscript; available in PMC 2016 Sep 26.
Published in final edited form as: Nature. 2015 Sep 17; 525(7569): 339–344. Published online 2015 Sep 7. doi: 10.1038/nature14877
PMCID:
PMC5036527
AbstractArticlePDF–4.7M
13.
Enzyme Architecture: Optimization of Transition State Stabilization from a Cation–Phosphodianion Pair
Archie C. Reyes, Astrid P. Koudelka, Tina L. Amyes, John P. Richard
J Am Chem Soc. 2015 Apr 29; 137(16): 5312–5315. Published online 2015 Apr 17. doi: 10.1021/jacs.5b02202
PMCID:
PMC4416717
AbstractArticlePDF–819K
14.
A compound heterozygous mutation in GPD1 causes hepatomegaly, steatohepatitis, and hypertriglyceridemia
Mugdha Joshi, Jacqueline Eagan, Nirav K Desai, Stephanie A Newton, Meghan C Towne, Nicholas S Marinakis, Kristyn M Esteves, Sarah De Ferranti, Michael J Bennett, Adam McIntyre, Alan H Beggs, Gerard T Berry, Pankaj B Agrawal
Eur J Hum Genet. 2014 Oct; 22(10): 1229–1232. Published online 2014 Feb 19. doi: 10.1038/ejhg.2014.8
PMCID:
PMC4169545
AbstractArticlePDF–820K
15.
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome
Gaëlle Blandin, Sylvie Marchand, Karine Charton, Nathalie Danièle, Evelyne Gicquel, Jean-Baptiste Boucheteil, Azéddine Bentaib, Laetitia Barrault, Daniel Stockholm, Marc Bartoli, Isabelle Richard
Skelet Muscle. 2013; 3: 3. Published online 2013 Feb 15. doi: 10.1186/2044-5040-3-3
PMCID:
PMC3610214
AbstractArticlePDF–1.7M
16.
Toward an understanding of the protein interaction network of the human liver
Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang
Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67
Correction in:
Mol Syst Biol. 2017 Dec; 13(12): 965.
PMCID:
PMC3261708
AbstractArticlePDF–2.0M
17.
Transient Infantile Hypertriglyceridemia, Fatty Liver, and Hepatic Fibrosis Caused by Mutated GPD1, Encoding Glycerol-3-Phosphate Dehydrogenase 1
Lina Basel-Vanagaite, Noam Zevit, Adi Har Zahav, Liang Guo, Saj Parathath, Metsada Pasmanik-Chor, Adam D. McIntyre, Jian Wang, Adi Albin-Kaplanski, Corina Hartman, Daphna Marom, Avraham Zeharia, Abir Badir, Oded Shoerman, Amos J. Simon, Gideon Rechavi, Mordechai Shohat, Robert A. Hegele, Edward A. Fisher, Raanan Shamir
Am J Hum Genet. 2012 Jan 13; 90(1): 49–60. doi: 10.1016/j.ajhg.2011.11.028
PMCID:
PMC3257852
AbstractArticlePDF–1.3M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Decreased levels of metabolic enzymes in pancreatic islets of patients with type 2 diabetes
M. J. MacDonald, M. J. Longacre, E.-C. Langberg, A. Tibell, M. A. Kendrick, T. Fukao, C.-G. Ostenson
Diabetologia. Author manuscript; available in PMC 2010 Jul 13.
Published in final edited form as: Diabetologia. 2009 Jun; 52(6): 1087–1091. Published online 2009 Mar 19. doi: 10.1007/s00125-009-1319-6
PMCID:
PMC2903059
AbstractArticlePDF–442K
20.
Large-Scale Proteomics and Phosphoproteomics of Urinary Exosomes
Patricia A. Gonzales, Trairak Pisitkun, Jason D. Hoffert, Dmitry Tchapyjnikov, Robert A. Star, Robert Kleta, Nam Sun Wang, Mark A. Knepper
J Am Soc Nephrol. 2009 Feb; 20(2): 363–379. doi: 10.1681/ASN.2008040406
PMCID:
PMC2637050
AbstractArticle

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