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Select item 109593731.

Transcriptome analyses describe the consequences of persistent HIF-1 over-activation in Caenorhabditis elegans

Dingxia Feng, Long Qu, Jo Anne Powell-Coffman

PLoS One. 2024; 19(3): e0295093. Published online 2024 Mar 22. doi: 10.1371/journal.pone.0295093

PMCID:: PMC10959373

Abstract Article PDF–1.0M

Select item 109425452.

Hypoxia-inducible factor induces cysteine dioxygenase and promotes cysteine homeostasis in Caenorhabditis elegans

Kurt Warnhoff, Sushila Bhattacharya, Jennifer Snoozy, Peter C Breen, Gary Ruvkun

eLife. 2024; 12: RP89173. Published online 2024 Feb 13. doi: 10.7554/eLife.89173

PMCID:: PMC10942545

Abstract Article PDF–3.0M

Select item 106465543.

Thiol reductive stress activates the hypoxia response pathway

Ravi, Ajay Kumar, Shalmoli Bhattacharyya, Jogender Singh

EMBO J. 2023 Nov; 42(22): e114093. Published online 2023 Oct 2. doi: 10.15252/embj.2023114093

PMCID:: PMC10646554

Abstract Article PDF–2.5M

Select item 105538194.

ADAR-mediated regulation of PQM-1 expression in neurons impacts gene expression throughout C. elegans and regulates survival from hypoxia

Ananya Mahapatra, Alfa Dhakal, Aika Noguchi, Pranathi Vadlamani, Heather A. Hundley

PLoS Biol. 2023 Sep; 21(9): e3002150. Published online 2023 Sep 25. doi: 10.1371/journal.pbio.3002150

PMCID:: PMC10553819

Abstract Article PDF–1.7M

Select item 96915425.

Co-opted genes of algal origin protect C. elegans against cyanogenic toxins

Bingying Wang, Taruna Pandey, Yong Long, Sofia E. Delgado-Rodriguez, Matthew D. Daugherty, Dengke K. Ma

Curr Biol. Author manuscript; available in PMC 2023 Nov 21.

Published in final edited form as: Curr Biol. 2022 Nov 21; 32(22): 4941–4948.e3. Published online 2022 Oct 11. doi: 10.1016/j.cub.2022.09.041

PMCID:: PMC9691542

Abstract Article PDF–1.9M

Select item 95791516.

The hypoxia response pathway promotes PEP carboxykinase and gluconeogenesis in C. elegans

Mehul Vora, Stephanie M. Pyonteck, Tatiana Popovitchenko, Tarmie L. Matlack, Aparna Prashar, Nanci S. Kane, John Favate, Premal Shah, Christopher Rongo

Nat Commun. 2022; 13: 6168. Published online 2022 Oct 18. doi: 10.1038/s41467-022-33849-x

PMCID:: PMC9579151

Abstract Article PDF–2.9M

Select item 95481817.

Dietary-derived vitamin B12 protects Caenorhabditis elegans from thiol-reducing agents

Alan D. Winter, Elissa Tjahjono, Leonardo J. Beltrán, Iain L. Johnstone, Neil J. Bulleid, Antony P. Page

BMC Biol. 2022; 20: 228. Published online 2022 Oct 8. doi: 10.1186/s12915-022-01415-y

PMCID:: PMC9548181

Abstract Article PDF–2.5M

Select item 92492238.

ROS and cGMP signaling modulate persistent escape from hypoxia in Caenorhabditis elegans

Lina Zhao, Lorenz A. Fenk, Lars Nilsson, Niko Paresh Amin-Wetzel, Nelson Javier Ramirez-Suarez, Mario de Bono, Changchun Chen

PLoS Biol. 2022 Jun; 20(6): e3001684. Published online 2022 Jun 21. doi: 10.1371/journal.pbio.3001684

PMCID:: PMC9249223

Abstract Article PDF–3.5M

Select item 87531229.

Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes

Manusnan Suriyalaksh, Celia Raimondi, Abraham Mains, Anne Segonds-Pichon, Shahzabe Mukhtar, Sharlene Murdoch, Rebeca Aldunate, Felix Krueger, Roger Guimerà, Simon Andrews, Marta Sales-Pardo, Olivia Casanueva

iScience. 2022 Jan 21; 25(1): 103663. Published online 2021 Dec 20. doi: 10.1016/j.isci.2021.103663

PMCID:: PMC8753122

Abstract Article PDF–4.6M

Select item 827012610.

Crosstalk in oxygen homeostasis networks: SKN-1/NRF inhibits the HIF-1 hypoxia-inducible factor in Caenorhabditis elegans

Dingxia Feng, Zhiwei Zhai, Zhiyong Shao, Yi Zhang, Jo Anne Powell-Coffman

PLoS One. 2021; 16(7): e0249103. Published online 2021 Jul 9. doi: 10.1371/journal.pone.0249103

PMCID:: PMC8270126

Abstract Article PDF–1.6M

Select item 773292211.

Hypoxic response regulators RHY-1 and EGL-9/PHD promote longevity through a VHL-1-independent transcriptional response

Joseph C.P. Kruempel, Hillary A. Miller, Megan L. Schaller, Abrielle Fretz, Marshall Howington, Marjana Sarker, Shijiao Huang, Scott F. Leiser

GeroScience. 2020 Dec; 42(6): 1621–1633. Published online 2020 May 12. doi: 10.1007/s11357-020-00194-0

PMCID:: PMC7732922

Abstract Article PDF–1.2M

Select item 705249312.

HIF-1 Has a Central Role in Caenorhabditis elegans Organismal Response to Selenium

Laura Romanelli-Credrez, Maria Doitsidou, Mark J. Alkema, Gustavo Salinas

Front Genet. 2020; 11: 63. Published online 2020 Feb 25. doi: 10.3389/fgene.2020.00063

PMCID:: PMC7052493

Abstract Article PDF–1.8M

Select item 704167713.

The stress-responsive gene GDPGP1/mcp-1 regulates neuronal glycogen metabolism and survival

Alexander Schulz, Yuichi Sekine, Motunrayo J. Oyeyemi, Alexander J. Abrams, Manasa Basavaraju, Sung Min Han, Marco Groth, Helen Morrison, Stephen M. Strittmatter, Marc Hammarlund

J Cell Biol. 2020 Feb 3; 219(2): e201807127. Published online 2020 Jan 22. doi: 10.1083/jcb.201807127

PMCID:: PMC7041677

Abstract Article PDF–2.5M

Select item 692013214.

Ferritin is regulated by a neuro-intestinal axis in the nematode Caenorhabditis elegans

Leonor Romero-Afrima, Veronica Zelmanovich, Zohar Abergel, Binyamin Zuckerman, Maayan Shaked, Rachel Abergel, Leonid Livshits, Yoav Smith, Einav Gross

Redox Biol. 2020 Jan; 28: 101359. Published online 2019 Oct 25. doi: 10.1016/j.redox.2019.101359