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Items: 1 to 20 of 337

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer
Maria Zagorulya, Leon Yim, Duncan M. Morgan, Austin Edwards, Elen Torres-Mejia, Noor Momin, Chloe V. McCreery, Izabella L. Zamora, Brendan L. Horton, James G. Fox, K. Dane Wittrup, J. Christopher Love, Stefani Spranger
Immunity. Author manuscript; available in PMC 2024 Feb 21.
Published in final edited form as: Immunity. 2023 Feb 14; 56(2): 386–405.e10. Published online 2023 Feb 2. doi: 10.1016/j.immuni.2023.01.010
PMCID:
PMC10880816
AbstractArticlePDF–3.2M
3.
Elimination of Chlamydia muridarum from the female reproductive tract is IL-12p40 dependent, but independent of Th1 and Th2 cells
Jordan A. Rixon, Kevin D. Fong, Claire Morris, Alana T. Nguyen, Claire E. Depew, Stephen J. McSorley
PLoS Pathog. 2024 Jan; 20(1): e1011914. Published online 2024 Jan 2. doi: 10.1371/journal.ppat.1011914
PMCID:
PMC10786385
AbstractArticlePDF–2.5M
4.
TCR-independent CD137 (4–1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation
Andrea C. Pichler, Nadège Carrié, Marine Cuisinier, Samira Ghazali, Allison Voisin, Pierre-Paul Axisa, Marie Tosolini, Céline Mazzotti, Dominic P. Golec, Sabrina Maheo, Laura do Souto, Rüçhan Ekren, Eve Blanquart, Lea Lemaitre, Virginie Feliu, Marie-Véronique Joubert, Jennifer L. Cannons, Camille Guillerey, Hervé Avet-Loiseau, Tania H. Watts, Benoit L. Salomon, Olivier Joffre, Yenkel Grinberg-Bleyer, Pamela L. Schwartzberg, Liliana E. Lucca, Ludovic Martinet
Immunity. Author manuscript; available in PMC 2023 Nov 15.
Published in final edited form as: Immunity. 2023 Jul 11; 56(7): 1631–1648.e10. Published online 2023 Jun 30. doi: 10.1016/j.immuni.2023.06.007
PMCID:
PMC10649891
AbstractArticlePDF–3.7M
5.
Intravenous heterologous prime-boost vaccination activates innate and adaptive immunity to promote tumor regression
Ramiro A. Ramirez-Valdez, Faezzah Baharom, Ahad Khalilnezhad, Sloane C. Fussell, Dalton J. Hermans, Alexander M. Schrager, Kennedy K.S. Tobin, Geoffrey M. Lynn, Shabnam Khalilnezhad, Florent Ginhoux, Benoit J. Van den Eynde, Carol Sze Ki Leung, Andrew S. Ishizuka, Robert A. Seder
Cell Rep. Author manuscript; available in PMC 2023 Oct 23.
Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112599. Published online 2023 Jun 7. doi: 10.1016/j.celrep.2023.112599
PMCID:
PMC10592466
AbstractArticlePDF–2.5M
6.
Sterile liver injury induces a protective tissue-resident cDC1-ILC1 circuit through cDC1-intrinsic cGAS-STING-dependent IL-12 production
Andrew D. Hildreth, Eddie T. Padilla, Rana Yakhshi Tafti, Akshara R. Legala, Timothy E. O’Sullivan
Cell Rep. Author manuscript; available in PMC 2023 Oct 23.
Published in final edited form as: Cell Rep. 2023 Feb 28; 42(2): 112141. Published online 2023 Feb 18. doi: 10.1016/j.celrep.2023.112141
PMCID:
PMC10435668
AbstractArticlePDF–2.5M
7.
Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity
Leyuan Ma, Alexander Hostetler, Duncan M. Morgan, Laura Maiorino, Ina Sulkaj, Charles A. Whittaker, Alexandra Neeser, Ivan Susin Pires, Parisa Yousefpour, Justin Gregory, Kashif Qureshi, Jonathan Dye, Wuhbet Abraham, Heikyung Suh, Na Li, J. Christopher Love, Darrell J. Irvine
Cell. Author manuscript; available in PMC 2023 Jul 27.
Published in final edited form as: Cell. 2023 Jul 20; 186(15): 3148–3165.e20. Published online 2023 Jul 5. doi: 10.1016/j.cell.2023.06.002
PMCID:
PMC10372881
AbstractArticlePDF–3.0M
8.
A neutrophil response linked to tumor control in immunotherapy
Jeremy Gungabeesoon, Nicolas A. Gort-Freitas, Máté Kiss, Evangelia Bolli, Marius Messemaker, Marie Siwicki, Mehdi Hicham, Ruben Bill, Peter Koch, Chiara Cianciaruso, Florent Duval, Christina Pfirschke, Michael Mazzola, Solange Peters, Krisztian Homicsko, Christopher Garris, Ralph Weissleder, Allon M. Klein, Mikael J. Pittet
Cell. Author manuscript; available in PMC 2024 Mar 30.
Published in final edited form as: Cell. 2023 Mar 30; 186(7): 1448–1464.e20. doi: 10.1016/j.cell.2023.02.032
PMCID:
PMC10132778
AbstractArticlePDF–2.7M
9.
IL-12p40 is essential but not sufficient for Francisella tularensis LVS clearance in chronically infected mice
Lara R. Mittereder, Jonathan Swoboda, Roberto De Pascalis, Karen L. Elkins
PLoS One. 2023; 18(3): e0283161. Published online 2023 Mar 27. doi: 10.1371/journal.pone.0283161
PMCID:
PMC10042368
AbstractArticlePDF–1.1M
10.
Leukemia inhibitory factor protects against graft-versus-host disease while preserving graft-versus-leukemia activity
Jianming Wang, Chun-Yuan Chang, Xue Yang, Fan Zhou, Juan Liu, Sining Zhu, Xue-Zhong Yu, Chen Liu, Timothy E. O’Sullivan, Ping Xie, Zhaohui Feng, Wenwei Hu
Blood. 2022 Nov 10; 140(19): 2076–2090. Published online 2022 Aug 22. doi: 10.1182/blood.2022015677
PMCID:
PMC9837439
AbstractArticle
11.
cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory
David A. Christian, Thomas A. Adams, II, Lindsey A. Shallberg, Anthony T. Phan, Tony E. Smith, Mosana Abraha, Joseph Perry, Gordon Ruthel, Joseph T. Clark, Gretchen Harms Pritchard, Lillian R. Aronson, Selamawit Gossa, Dorian B. McGavern, Ross M. Kedl, Christopher A. Hunter
Sci Immunol. Author manuscript; available in PMC 2023 Mar 30.
Published in final edited form as: Sci Immunol. 2022 Sep 30; 7(75): eabq7432. Published online 2022 Sep 30. doi: 10.1126/sciimmunol.abq7432
PMCID:
PMC9835709
AbstractArticlePDF–2.7M
12.
Cytotoxic CD4+ T cells driven by T-cell intrinsic IL-18R/MyD88 signaling predominantly infiltrate Trypanosoma cruzi-infected hearts
Carlos-Henrique D Barbosa, Fábio B Canto, Ariel Gomes, Layza M Brandao, Jéssica R Lima, Guilherme A Melo, Alessandra Granato, Eula GA Neves, Walderez O Dutra, Ana-Carolina Oliveira, Alberto Nóbrega, Maria Bellio
eLife. 2022; 11: e74636. Published online 2022 Jun 7. doi: 10.7554/eLife.74636
PMCID:
PMC9236613
AbstractArticlePDF–12M
13.
ILC precursors differentiate into metabolically distinct ILC1-like cells during Mycobacterium tuberculosis infection
Dan Corral, Alison Charton, Maria Z. Krauss, Eve Blanquart, Florence Levillain, Emma Lefrançais, Tamara Sneperger, Zoï Vahlas, Jean-Philippe Girard, Gérard Eberl, Yannick Poquet, Jean-Charles Guéry, Rafael J. Argüello, Yasmine Belkaid, Katrin D. Mayer-Barber, Matthew R. Hepworth, Olivier Neyrolles, Denis Hudrisier
Cell Rep. 2022 Apr 19; 39(3): 110715. Published online 2022 Apr 19. doi: 10.1016/j.celrep.2022.110715
PMCID:
PMC9043616
AbstractArticlePDF–2.4M
14.
Transcriptional changes in dendritic cells underlying allergen specific induced tolerance in a mouse model
Rafael Nuñez, Maria Jose Rodriguez, Francisca Palomares, Francisca Gomez, Fernando M. Jabato, Jose Cordoba-Caballero, Pedro Seoane, Jorge Losada, Javier Rojo, Maria Jose Torres, James Richard Perkins, Cristobalina Mayorga
Sci Rep. 2022; 12: 2797. Published online 2022 Feb 18. doi: 10.1038/s41598-022-06186-8
PMCID:
PMC8857182
AbstractArticlePDF–3.7M
15.
CXCR6 Positions Cytotoxic T Cells to Receive Critical Survival Signals in the Tumor Microenvironment
Mauro Di Pilato, Raphael Kfuri-Rubens, Jasper N. Pruessmann, Aleksandra J. Ozga, Marius Messemaker, Bruno L. Cadilha, Ramya Sivakumar, Chiara Cianciaruso, Ross D. Warner, Francesco Marangoni, Esteban Carrizosa, Stefanie Lesch, James Billingsley, Daniel Perez-Ramos, Fidel Zavala, Esther Rheinbay, Andrew D. Luster, Michael Y. Gerner, Sebastian Kobold, Mikael J. Pittet, Thorsten R. Mempel
Cell. Author manuscript; available in PMC 2022 Aug 19.
Published in final edited form as: Cell. 2021 Aug 19; 184(17): 4512–4530.e22. Published online 2021 Aug 2. doi: 10.1016/j.cell.2021.07.015
PMCID:
PMC8719451
AbstractArticlePDF–4.3M
16.
Commensal Cryptosporidium colonization elicits a cDC1-dependent Th1 response that promotes intestinal homeostasis and restricts other infections
Emilie V. Russler-Germain, Jisun Jung, Aidan T. Miller, Shannon Young, Jaeu Yi, Alec Wehmeier, Lindsey E. Fox, Kristen J. Monte, Jiani N. Chai, Devesha H. Kulkarni, Lisa J. Funkhouser-Jones, Georgia Wilke, Vivek Durai, Bernd H. Zinselmeyer, Rafael S. Czepielewski, Suellen Greco, Kenneth M. Murphy, Rodney D. Newberry, L. David Sibley, Chyi-Song Hsieh
Immunity. Author manuscript; available in PMC 2022 Nov 9.
Published in final edited form as: Immunity. 2021 Nov 9; 54(11): 2547–2564.e7. Published online 2021 Oct 28. doi: 10.1016/j.immuni.2021.10.002
PMCID:
PMC8716016
AbstractArticlePDF–3.4M
17.
Tryptophan (W) at position 37 of murine IL-12/IL-23 p40 is mandatory for binding to IL-12Rβ1 and subsequent signal transduction
Jacqueline Georgy, Yvonne Arlt, Jens M. Moll, Meryem Ouzin, Hendrik T. Weitz, Lothar Gremer, Dieter Willbold, Joachim Grötzinger, Felix Thives-Kurenbach, Jürgen Scheller, Doreen M. Floss
J Biol Chem. 2021 Nov; 297(5): 101295. Published online 2021 Oct 9. doi: 10.1016/j.jbc.2021.101295
PMCID:
PMC8571081
AbstractArticlePDF–3.2M
18.
The subunits of IL-12, originating from two distinct cells, can functionally synergize to protect against pathogen dissemination in vivo
Allison N. Gerber, Kaveh Abdi, Nevil J. Singh
Cell Rep. Author manuscript; available in PMC 2021 Nov 5.
Published in final edited form as: Cell Rep. 2021 Oct 12; 37(2): 109816. doi: 10.1016/j.celrep.2021.109816
PMCID:
PMC8569637
AbstractArticlePDF–1.6M
19.
Inhibition of a BTK-IDO-mTOR axis promotes differentiation of monocyte-lineage inflammatory dendritic cells and enhances anti-tumor T cell immunity
Madhav D. Sharma, Rafal Pacholczyk, Huidong Shi, Zuzana J. Berrong, Yousef Zakharia, Austin Greco, Chang-Sheng S. Chang, Sudharshan Eathiraj, Eugene Kennedy, Thomas Cash, Roni J. Bollag, Ravindra Kolhe, Ramses Sadek, Tracy L. McGaha, Paulo Rodriguez, Jessica Mandula, Bruce R. Blazar, Theodore S. Johnson, David H. Munn
Immunity. Author manuscript; available in PMC 2022 Oct 12.
Published in final edited form as: Immunity. 2021 Oct 12; 54(10): 2354–2371.e8. Published online 2021 Oct 5. doi: 10.1016/j.immuni.2021.09.005
PMCID:
PMC8516719
AbstractArticlePDF–1.6M
20.
Induction of IL-12p40 and type 1 immunity by Toxoplasma gondii in the absence of the TLR-MyD88 signaling cascade
Lindsay M. Snyder, Claire M. Doherty, Heather L. Mercer, Eric Y. Denkers
PLoS Pathog. 2021 Oct; 17(10): e1009970. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009970
PMCID:
PMC8513874
AbstractArticlePDF–3.5M

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