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Select item 112293351.

The translocation activity of Rad54 reduces crossover outcomes during homologous recombination

Krishay Sridalla, Mitchell V Woodhouse, Jingyi Hu, Jessica Scheer, Bryan Ferlez, J Brooks Crickard

Nucleic Acids Res. 2024 Jul 8; 52(12): 7031–7048. Published online 2024 Jun 3. doi: 10.1093/nar/gkae474

PMCID:: PMC11229335

Abstract Article PDF–2.2M

Select item 111547082.

Identification of a chaperone-code responsible for Rad51-mediated genome repair

Khushboo Rani, Akanksha Gotmare, Andreas Maier, Ruchira Menghal, Nashat Akhtar, Nupur Fangaria, Johannes Buchner, Sunanda Bhattacharyya

J Biol Chem. 2024 Jun; 300(6): 107342. Published online 2024 May 3. doi: 10.1016/j.jbc.2024.107342

PMCID:: PMC11154708

Abstract Article PDF–3.4M

Select item 111094833.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 109909314.

Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site

Takuro Shioi, Suguru Hatazawa, Eriko Oya, Noriko Hosoya, Wataru Kobayashi, Mitsuo Ogasawara, Takehiko Kobayashi, Yoshimasa Takizawa, Hitoshi Kurumizaka

Nature. 2024; 628(8006): 212–220. Published online 2024 Mar 20. doi: 10.1038/s41586-024-07196-4

PMCID:: PMC10990931

Abstract Article PDF–20M

Select item 108724775.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107143966.

Potency of CRISPR-Cas Antifungals Is Enhanced by Cotargeting DNA Repair and Growth Regulatory Machinery at the Genetic Level

Brian J. Mendoza, Xianliang Zheng, Jared C. Clements, Christopher Cotter, Cong T. Trinh

ACS Infect Dis. 2023 Dec 8; 9(12): 2494–2503. Published online 2023 Nov 13. doi: 10.1021/acsinfecdis.3c00342

PMCID:: PMC10714396

Abstract Article PDF–4.4M

Select item 107001387.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 106225118.

Double-strand breaks induce inverted duplication chromosome rearrangements by a DNA polymerase δ-dependent mechanism

Amr M. Al-Zain, Mattie R. Nester, Iffat Ahmed, Lorraine S. Symington

Nat Commun. 2023; 14: 7020. Published online 2023 Nov 2. doi: 10.1038/s41467-023-42640-5

PMCID:: PMC10622511

Abstract Article PDF–5.4M

Select item 105561419.

Yeast Rad52 is a homodecamer and possesses BRCA2-like bipartite Rad51 binding modes

Jaigeeth Deveryshetty, Rahul Chadda, Jenna R. Mattice, Simrithaa Karunakaran, Michael J. Rau, Katherine Basore, Nilisha Pokhrel, Noah Englander, James A. J. Fitzpatrick, Brian Bothner, Edwin Antony

Nat Commun. 2023; 14: 6215. Published online 2023 Oct 5. doi: 10.1038/s41467-023-41993-1

PMCID:: PMC10556141

Abstract Article PDF–3.2M

Select item 1055032110.

Mitochondrial superoxide dismutase Sod2 suppresses nuclear genome instability during oxidative stress

Sonia Vidushi Gupta, Lillian Campos, Kristina Hildegard Schmidt

Genetics. 2023 Oct; 225(2): iyad147. Published online 2023 Aug 29. doi: 10.1093/genetics/iyad147

PMCID:: PMC10550321

Abstract Article PDF–1.2M

Select item 1040007811.

Long-range DNA end resection supports homologous recombination by checkpoint activation rather than extensive homology generation

Michael T Kimble, Matthew J Johnson, Mattie R Nester, Lorraine S Symington

eLife. 2023; 12: e84322. Published online 2023 Jun 30. doi: 10.7554/eLife.84322

PMCID:: PMC10400078

Abstract Article PDF–3.7M

Select item 1039960912.

Helicase activities of Rad5 and Rrm3 genetically interact in the prevention of recombinogenic DNA lesions in Saccharomyces cerevisiae

Julius Muellner, Kristina Hildegard Schmidt

DNA Repair (Amst) Author manuscript; available in PMC 2024 Jun 1.

Published in final edited form as: DNA Repair (Amst). 2023 Jun; 126: 103488. Published online 2023 Mar 30. doi: 10.1016/j.dnarep.2023.103488

PMCID:: PMC10399609

Abstract Article PDF–1.0M

Select item 1029770013.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 1028792114.

Saccharomyces cerevisiae DNA polymerase IV overcomes Rad51 inhibition of DNA polymerase δ in Rad52-mediated direct-repeat recombination

Paula G Cerqueira, Damon Meyer, Lilin Zhang, Benjamin Mallory, Jie Liu, Becky Xu Hua Fu, Xiaoping Zhang, Wolf-Dietrich Heyer

Nucleic Acids Res. 2023 Jun 23; 51(11): 5547–5564. Published online 2023 Apr 18. doi: 10.1093/nar/gkad281

PMCID:: PMC10287921

Abstract Article PDF–1.8M

Select item 1028790515.

Proper RPA acetylation promotes accurate DNA replication and repair

Xiaoli Gan, Yueyue Zhang, Donghao Jiang, Jingyao Shi, Han Zhao, Chengyu Xie, Yanyan Wang, Jingyan Xu, Xinghua Zhang, Gang Cai, Hailong Wang, Jun Huang, Xuefeng Chen

Nucleic Acids Res. 2023 Jun 23; 51(11): 5565–5583. Published online 2023 May 4. doi: 10.1093/nar/gkad291

PMCID:: PMC10287905

Abstract Article PDF–3.3M

Select item 1021305016.

Bre1/RNF20 promotes Rad51-mediated strand exchange and antagonizes the Srs2/FBH1 helicases

Guangxue Liu, Jimin Li, Boxue He, Jiaqi Yan, Jingyu Zhao, Xuejie Wang, Xiaocong Zhao, Jingyan Xu, Yeyao Wu, Simin Zhang, Xiaoli Gan, Chun Zhou, Xiangpan Li, Xinghua Zhang, Xuefeng Chen

Nat Commun. 2023; 14: 3024. Published online 2023 May 25. doi: 10.1038/s41467-023-38617-z

PMCID:: PMC10213050

Abstract Article PDF–1.3M

Select item 1019502517.

Saccharomyces cerevisiae RAD53 (CHK2) but not CHK1 is required for double-strand break-initiated SCE and DNA damage-associated SCE after exposure to X rays and chemical agents

Michael Fasullo, Zheng Dong, Mingzeng Sun, Li Zeng

DNA Repair (Amst) Author manuscript; available in PMC 2023 May 18.

Published in final edited form as: DNA Repair (Amst). 2005 Nov 21; 4(11): 1240–1251. Published online 2005 Jul 21. doi: 10.1016/j.dnarep.2005.06.006

PMCID:: PMC10195025

Abstract Article PDF–714K

Select item 998453218.

Genetic requirements for repair of lesions caused by single genomic ribonucleotides in S phase

Natalie Schindler, Matthias Tonn, Vanessa Kellner, Jia Jun Fung, Arianna Lockhart, Olga Vydzhak, Thomas Juretschke, Stefanie Möckel, Petra Beli, Anton Khmelinskii, Brian Luke

Nat Commun. 2023; 14: 1227. Published online 2023 Mar 3. doi: 10.1038/s41467-023-36866-6